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Cimetidine H2 Antagonists Histamine receptors Histamine Anatomy Physiology Pharmacology Biochemistry Synthesis Formulation Side effects Practice Pharmacokinetics Stomach cells Ulcers Helicobacta Pathology Acid secretion Metabolism removal Development Chemistry Pharmaceutics NSAID Aspirin Interactions Therapeutic index Cautions Liver Kidney Doses Proton pump inhibitors Imidazole Gastrin Neural effects Antacids Clinical trials Misoprostol Dyspepsia QSAR Cholinerigic Zollinger Ellison Cytochrome P450

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Page 1: Cimetidine H2 Antagonists Histamine receptors Histamine AnatomyPhysiology Pharmacology Biochemistry Synthesis Formulation Side effects Practice Pharmacokinetics

CimetidineH2 Antagonists

Histamine receptors

Histamine

Anatomy Physiology Pharmacology

Biochemistry

Synthesis

Formulation

Side effectsPractice

Pharmacokinetics

Stomach cells

Ulcers

Helicobacta

Pathology

Acidsecretion

Metabolism removal

Development

Chemistry

Pharmaceutics

NSAID Aspirin

InteractionsTherapeutic index

Cautions

Liver

Kidney

Doses

Proton pump inhibitors

Imidazole

Gastrin

Neural effects

Antacids

Clinical trials

Misoprostol

Dyspepsia

QSAR

Cholinerigic

ZollingerEllison

Cytochrome P450

Page 2: Cimetidine H2 Antagonists Histamine receptors Histamine AnatomyPhysiology Pharmacology Biochemistry Synthesis Formulation Side effects Practice Pharmacokinetics

Ranitidine

H2 Antagonists

Histamine receptors

Histamine

Stomach cells

Gastric ulcersHelicobacta

Acidsecretion

NSAID

Proton pump inhibitors

Gastrin

Neural effects

Antacids

Misoprostol

Dyspepsia

Cholinerigic

Duodenal ulcers

Gastritis

Acid refluxGORD

Calciumantagonists

Gastric cancer

Famotidine

Cimetidine

Nizatidine

Hernia

Antibiotics

ZollingerEllison

Endoscopy

Aspirin

NausiaAngina

Duodenitis

Corticosteroids Vomiting

Page 3: Cimetidine H2 Antagonists Histamine receptors Histamine AnatomyPhysiology Pharmacology Biochemistry Synthesis Formulation Side effects Practice Pharmacokinetics

Cimetidine

H2 Antagonists

Histamine receptors

Histamine

Parietal cells

UlcersHelicobacta

Acid secretionNSAID Aspirin

Proton pump inhibitors

Gastrin

Parasympathetic NS

Antacids

Misoprostol

Dyspepsia

Cholinerigic receptors

ZollingerEllison

Vagus nerve

G cells

D cells

ECL cells

Ranitidine

Omeprazole

H+/K+ ATPase,

Somatostatin.

Cholecystokinin

Pepsin

Gastric mucosa.

Hydrochloric acid

pH

Bicarbonate

Achlorhydria

Famotidine

Hypercalcaemia

Page 4: Cimetidine H2 Antagonists Histamine receptors Histamine AnatomyPhysiology Pharmacology Biochemistry Synthesis Formulation Side effects Practice Pharmacokinetics

Cimetidine

H2 Antagonists

Histamine receptors

Histamine

Synthesis

FormulationPharmacokinetics

Metabolism removal

Development

Cytochrome P450

Imidazole

QSAR

BurimamideCompetitive antagonist

Antihistamines Metiamide

NephrotoxicityAgranulocytosis

pKa

Adverse effects

Furan

Peptic ulcer

Dyspepsia

GORD

Inverse agonist

Thiourea

Guanidine Famotidine

Guanidinothiazole

Bioavailability

Thiazole

Nizatidine

Ranitidine


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