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Chronic inflammationand

Heart diseaseDr. Fathi Neana, MD

Chief of OrthopaedicsDr. Fakhry & Alrajhy Hospital

Saudi ArabiaDecember, 2 – 2016

How to Lower the Risk of Heart Disease Without Drugs

Many concepts are changed as we are in the era of evidence based medicine

In the way to understand Heart disease risk factors we face many questions

1- A diet low in saturated fat 'will not prevent heart disease or prolong life‘ and cholesterol is not the culprit

2- Cholesterol-lowering medications are not a magic bullets to lower the risk of dying from heart disease and its side effects

are well studied & known

3- Our body needs Cholesterol for optimal functioning

How to Lower the Risk of Heart Disease Without Drugs

1- A diet low in saturated fat 'will not prevent heart disease or prolong life‘ and

cholesterol is not the culprit

LOW FAT MESSAGE ABANDONED No link between heart disease and Total fat, Saturated fat and Dietary cholesterol A.C.C - A.H.A 2015 USDGAG JAMA 2 – 2016

PROCESSED FOODS IS THE CULPRIT

Sugars, Non fiber carb and Transfats

Effect is worse by Smoking , Alcohol,

Addiction

Cardiovascular Disease (CVD) risk

Why There is Essential fatty and amino

acidsBut No essential carb or sugar

World Health Organization MONICA study(MONICA : multinational MONITORING trends and determinants

in CADIOVASCULAR disease)14 European countries + urban Australian Aborigines

10 years7 million people

40 studies collected The ten year data collection was completed in the late 1990s,

Dr. Malcolm Kendrick MD . "The Great Cholesterol Myth". July 2011.

As any person (no medical experience needed) with eyes can see, the Aborigines had the lowest cholesterol and the highest death rate from heart disease.

The U.S. Preventive Services Task Force (USPSTF) has issued a new recommendation statement regarding the use of statins for primary prevention of cardiovascular disease (CVD) in adults

It is recommending a low- to moderate-dose statin in adults ages 40-75 years without a history of CVD who have 1 or more CVD risk factors and a calculated 10-year CVD event risk of 10 per cent or greater

Where the calculated 10-year CVD event risk is in the range of 7.5 to 10 per cent, the task force recommends selective use of low- to moderate-dose therapy.

USPSTF concludes that current evidence is insufficient to assess the balance of benefits and harms of initiating statin use in adults aged 76 years and older without a history of heart attack or stroke.

New recommendations on the use of statins for primary CVD preventionUnivadis - Nov 16, 2016

The task force evidence report estimates

An absolute benefit for use of statins of

0.40 per cent for all-cause mortality

0.43 per cent for cardiovascular mortality

The absolute benefit was greater for patients at greater baseline risk

New recommendations on the use of statins for primary CVD preventionUnivadis - Nov 16, 2016

Hyperglycaemia

HyperinsulinemiaInsuin resistance

Metabolic syndrome Diabetus ii

DyslipidaemiaObesity

Atherosclerotic plaque CHD

9The typical atherosclerotic plaque comprises of the lipid core and the fibrous cap The most commonly classified histologically by the American Heart Association

Plaque formation

1- Small dense LDL type B particles

2- Vessel wall inflammation – increased endothelial permeability

3- Foam cell apoptosis

Prevention of Plaque formationA- Pre vessel wall

Treat the cause (small dense LDL particles) 1- Anti-inflammatory lifestyle

2- Control of Insulin - Leptin resistance(Diet too high in sugars + Obesity)

B- At vessel wallTreat the inflamed vessel wall

STATIN : Nuclear factor KAPPA B-> anti-inflammatory – vessel wall permeability

C- Post vessel wallPrevent Autophagy of Foam cells

(Foam cell apoptosis ) Japanese research

November 2016 Nobel Prize

Yoshinori Ohsumi

Now that you’ve seen cholesterol medication’s side effects, you might be wondering how to reduce cholesterol naturally

without using these harmful drugs.

But this may be the wrong question.

The real question that begs to be answered is …

“Does high cholesterol really cause heart disease?”You may be surprised to learn the answer to this.

We’ve Been Asking the Wrong Question

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HEALTH: Cholesterol: The big fat lie, plus how to prevent heart disease By SARAH STACEY FOR THE MAIL ON SUNDAY

PUBLISHED: 00:02 GMT, 12 July 2015 | UPDATED: 00:04 GMT, 12 July 2015

How to Lower the Risk of Heart Disease Without Drugs

2- Cholesterol-lowering medications are not a magic bullets to lower the risk of dying from heart disease and its side

effects are well studied & known

16

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Statins are not selective for SMALL DENSE LDL type B or even all Cholesterol types.

It is a broad spectrum anti Acetyl CoASide effects are numerous, benefits are

debatable. If you are taking statins for any reason it is imperative to take Coenzyme Q10.

Statins act by inhibiting HMG-CoA reductase.

as indicated in this figure.

All metabolic functions further down the Mevalonic acid pathway are

consequently affected. 

 

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Registered as a hepatoprotector) in relation to neurodegenerative diseases (including Alzheimer's

disease

Biosynthesis of biologically important N-linked glycoproteins.

A major part of glycoproteins are those for our  emotions, our neuropeptides.

Aggression, hostility, sensitivity, paranoia, road rage type feelings, depression, suicidal ideation, homocidal ideation and a number of both suicides and homocide attempts all associated with statin

drug use.

Dolichol, cholesterol, coenzyme Q10?Why we need Dolichol

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Dolichol, Cholesterol, Coenzyme Q10?Why we need Cholesterol

• Vitamin D precursor

• Precursor to Hormones Deal with stress (Cortisones)

Sex hormones (like estrogen, progesterone, & testosterone)

• Cell membrane) Rigidity to our cells organ dysfunction

• Keep the intestinal wall healthypreventing “leaky gut”

• Bile salts – Digestion of fats

• (Powerful antioxidant)Did you catch this last surprise ?

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Similar to a vitamin. It is found in every cell of the body. cells use it to produce energy , cell growth and maintenance. It is functions as an antioxidant & Coenzymes help enzymes to digest

food and perform other body processes, protect the heart and skeletal muscles.

What is CoQ10 used for?Help in :  heart failure, cancer, muscular dystrophy, periodontal

diseasesIt boost energy and speed recovery from exercises

Some people take it to help reduce the effects certain medicines on the heart, muscles, and other organs.

particularly high in organ meats such as heart, liver, and kidney, beef, soy oil, sardines, mackerel, and peanuts.

Dolichol, cholesterol, coenzyme Q10?Why we need Coenzyme Q10?

22

What is coenzyme Q10?

a substance similar to a vitamin. It is found in every cell of the body.

cells use it to produce energy , cell growth and maintenance. It also functions as an antioxidant,

particularly high in organ meats such as heart, liver, and kidney, beef, soy oil, sardines, mackerel, and peanuts.

Coenzymes help enzymes work to digest food and perform other body processes, help protect the heart and skeletal

muscles.

What is CoQ10 used for?It is said to help heart failure, as well as cancer, 

muscular dystrophy, and periodontal disease. It boost energy and speed recovery from exercise.

Some people take it to help reduce the effects certain medicines on the heart, muscles, and other organs.

What is Dolicholpharmaceutically registered as a hepatoprotector) in relation to neurodegenerative diseases

(including Alzheimer's disease) in both Russia [2] & Australia [3]

 indicate considerable potential as a safe and effective treatment.

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The Grave Dangers of Statin Drugs—and the Surprising Benefits of Cholesterol

 BY ANH-USA ON JULY 14, 2015

$29 billion worth of sales in 2013 .That’s the kind of outrageous money you make when you convince one in four Americans over the age of 45 to take statins.

Over the years we’ve reported on a wide range of negative health effects that have been linked to these drugs

Statins interfere with the production of coenzyme Q10weaken the immune systemmuscle and neurological problems, including Lou Gehrig’s DiseaseStatins inhibit the beneficial effects of omega-3 fatty acidsincreases insulin resistance and the risk of developing diabetesstatin use blocks the benefits of exercise.reducing the body’s ability to produce cholesterol, which isessential to brain health—the brain is 2% of the body’s weight, but contains 25% of the entire body’s cholesterol. nerve degeneration and pain,memory loss, confusion, depression, higher risk of ALS and Parkinson’sDr. David Williams in his July 2014 Alternativesnewsletter. Statins also decrease carotenoid levels. Carotenoids, which are found in fresh fruits and vegetables and act as antioxidants, have a number of benefits, including protecting against cell damage, aging, and chronic diseases., according

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Statin side effects: Weigh the benefits and risksBy Mayo Clinic Staff

What are statin side effects?

Muscle pain and damageThe most common statin side effect is muscle pain. You may feel this pain as a soreness,

tiredness or weakness in your muscles. Make daily activities difficult. can cause life-threatening muscle damage called rhabdomyolysis. cause severe muscle

pain, liver damage, kidney failure and death..Liver damage

Digestive problemsnausea, gas, diarrhea or constipation

Rash or flushingIncreased blood sugar or type 2 diabetes

the Food and Drug Administration (FDA) has issued a warning on statin labels regarding blood glucose levels and diabetes.

Neurological side effectsThe FDA warns on statin labels that some people have developed memory loss or

confusion

Muscle pain and weakness

Increased liver enzymes

Worsening asthma

Potential pregnancy

Using antibiotics or antifungal drugs

5 Reasons to Stop or Switch Statins

How to Lower the Risk of Heart Disease Without Drugs

3- Our body needs Cholesterol for optimal functioning

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What is Cholesterol?

A waxy substance – technically a sterol (unsaturated steroid alcohol)

>75% of your cholesterol is made in your liver, the rest is absorbed from food Synthesized in many cells, but

mostly in the liver and intestine

Cholesterol travels in particles called lipoproteins: high-density lipoproteins (HDL) and low-Density

Lipoproteins (LDL)

Acetyl coenzyme A (acetyl CoA) is the precursor to cholesterol synthesis

Why do we need Cholesterol ?

Vitamin D which is critical for all body systems including the bones, nerves, proper growth, mineral metabolism, muscle tone, insulin production, fertility, and strong immunity.

Sex hormones (testosterone, estrogen, progesterone and DHEA) Stress hormones (steroids - cortisol) These hormones also are protective against

heart disease and cancer. Bile acids for digestioncritical to the digestive process and absorption of dietary

fats. Contributes to normal Cell membrane function of nerve cells in the brain Proper functioning of the brain. Cholesterol is used by serotonin receptors ..

serotonin is the body’s natural “feel good” chemical.  No wonder low cholesterol levels have been associated with aggressive and violent tendencies, depression and suicide.

Why do we need Cholesterol ?

Serves as an Antioxidant (Neuroprotective) a powerful antioxidant in the body and is protective of free radical damage to tissues.

Breast milk is ideally rich in cholesterol and contains a special enzyme for the baby to properly utilize it. Babies and children need cholesterol for proper growth and development of the brain, nervous system, and immune function.

proper functioning of the intestines and maintaining the integrity of the intestinal wall.  Low cholesterol diets can lead to leaky gut syndrome and other digestive problems.

critical to Repair of damaged cells. This is why cholesterol levels naturally rise as we age and are beneficial to the elderly.  Women with the highest cholesterol actually live the longest!  

How to Lowerthe Risk of

Heart DiseaseWithout Drugs

Hyperglycaemia

HyperinsulinemiaInsuin resistance

Metabolic syndrome Diabetus ii

DyslipidaemiaObesity

Atherosclerotic plaque CHD

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What are Triglycerides?

Triglycerides are a type of fat (lipid) found in your blood

Your body converts any calories it doesn't need to use right away into triglycerides

Triglycerides are stored in your fat cells

Hormones release triglycerides for energy between meals

Regularly eat more calories than you burn will raise triglycerides and increase fat storage

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1- Anti-inflammatory lifestyle 2- Reversing insulin & leptin resistance

Proper diet, exercise, sun exposure, and grounding to the earth are the corner stones

How to Lower the Risk of Heart Disease Without Drugs

Cholesterol-lowering medications are not a magic bullets to lower the risk of dying from heart

disease. especially because our body needs Cholesterol for optimal functioning

35

Heart disease is the end result of unhealthy lifestyle choices

Cholesterol-lowering medications are not a magic bullets to lower the risk of dying from heart disease. especially because

our body needs  cholesterol for optimal functioning

Preventing cardiovascular disease is by Proper diet, exercise, sun exposure, and grounding to the earth

are corner stones of an (Anti-inflammatory lifestyle)

How to Lower the Risk of Heart Disease Without Drugs (Anti-inflammatory lifestyle)

36

No- or low-fat foods are processed foods - high in sugar, raises small, dense LDL particles.

Balancing omega -3 to omega-6 ratio, help build the cells that make prostacyclin that

keeps your blood flowing smoothly.

Appropriate ratios of calcium, magnesium,  sodium and potassium whole food diet. fresh vegetables  

Optimize your vitamin D level.

Optimize your gut health. Beneficial bacteria play a role in preventing heart disease and countless other health problems.

Quit smoking and alcohol - Exercise regularly - Pay attention to your oral health..

Statins, side effects are numerous, benefits are debatable. If you are taking statins for any reason it is imperative to take Coenzyme Q10.

How to Lower the Risk of Heart Disease Without Drugs (Anti-inflammatory lifestyle)

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What REALLY Constitutes a Heart-Healthy Diet?The following table outlines my version of a "heart-healthy diet," which

minimizes inflammation, reduces insulin resistance, and helps you reduce your risk for cardiovascular disease.

If you want further details, I suggest reviewing my Optimized Nutrition Plan, which will guide you through dietary changes in

a step-by-step fashion, moving from beginner to intermediate to advanced.

New Science Destroys the Saturated Fat Myth July 27, 2014 By Dr. Mercola

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1. Limit or eliminate all processed foods2. Eliminate all gluten and highly allergenic foods from your diet3. Eat organic foods whenever possible to avoid exposure to harmful agricultural chemicals, such as glyphosate4. Avoid genetically modified ingredients (GMO), which wreak biological chaos on a cellular level and are linked to abundant health problems, including chronic inflammation and heart disease5. Eat at least one-third of your food uncooked (raw), or as much as you can manage; avoid cooking foods at high temperatures6. Increase the amount of fresh vegetables in your diet, locally grown and organic if possible7. Eat naturally fermented foods, which help optimize your gut bacteria and prevent inflammation-causing superantigens from pathogenic bacteria, as well as providing valuable vitamin K2, B vitamins, and other nutrients

New Science Destroys the Saturated Fat Myth July 27, 2014 By Dr. Mercola

39

8. Avoid all artificial sweeteners.9. Limit fructose to less than 25 grams per day from all sources, including whole fruits. If you have insulin resistance, diabetes, hypertension, or heart disease, you'd be well advised to keep your fructose consumption below 15 grams per day until your insulin resistance  has normalized10. Swap all trans fats (vegetable oils, margarine etc.) for healthy fats like avocado, raw butter, cheese, and coconut oil; avoid consuming oxidized cholesterol (cholesterol that has gone rancid, such as that from overcooked scrambled eggs)11. To rebalance your omega-3 to omega-6 ratio, take a high-quality animal-based omega-3 supplement, such as krill oil, and reduce your consumption of processed omega-6 fats from vegetable oils12. Drink plenty of pure water every day

New Science Destroys the Saturated Fat Myth July 27, 2014 By Dr. Mercola

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Five Other Heart-Healthy Movesthere are several more strategies that can be profoundly helpful in reducing chronic inflammation and thereby lowering your cardiovascular risk:ti•Exercise regularly. One of the primary benefits of exercise is that it helps normalize and maintain healthy insulin and leptin levels. Exercise also boosts HDL, increases your growth hormone production, helps curb your appetite, and improves your mood and sleep.•Intermittent fasting. Fasting is an excellent way to "reboot" your metabolism so that your body can relearn how to burn fat as its primary fuel, which helps you shed those excess fat stores. Intermittent fasting has a far greater retention and compliance rate compared to conventional all-day fasting regimens. Another version is alternate-day fasting.•Grounding yourself to the earth. When you walk barefoot, free electrons are transferred from the earth into your body, and electrons are some of the most potent antioxidants known. Grounding (also called Earthing) helps alleviate inflammation, as well as thinning your blood and causing your red blood cells to repel each other, making them less likely to clot.•AVOID statin drugs. Statin drugs can reduce your cholesterol to dangerously low levels, while doingnothing tomodulate LDL particle size. Statin drugs may even accelerate heart disease. A 2012 study showed that statin use is associated with a 52 percent higher prevalence of calcified coronary plaquecompared to those not taking them.7 And coronary artery calcification is the hallmark of potentially lethal heart disease. Antidepressants have also been associated with heart disease.•AVOID chemicals whenever possible. BPA, for example, has been linked to heart disease: adults with the highest levels of BPA in the

New Science Destroys the Saturated Fat Myth July 27, 2014 - By Dr. Mercola

The decision whether to take them should be based on whether you have pre-existing heart disease, what your overall risk of a heart attack is, how healthy your diet and lifestyle is, what other treatments you’ve already tried, and your

own risk , tolerance and worldview.Dr. Joseph Mercola.

My intention here is not to suggest that statins have no place in the treatment of heart disease, but rather to initiate

brain storming and give you the objective information needed to (Decide along With your Doctor) whether they

are appropriate for You.

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REFERENCES

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6.Lexchin J, Bero LA, Djulbegovic B, Clark O. "Pharmaceutical industry sponsorship and research outcome and quality: systematic review." BMJ. 2003;326(7400):1167--1170. http://www.bmj.com/content/326/7400/1167.abstract?ijkey=9130651a991766c57c1a168de2819b23fe677709&keytype2=tf_ipsecsha7.https://www.youtube.com/watch?v=HcwTxRuq-uk8.Akira ENDO. "A historical perspective on the discovery of statins." Proc Jpn Acad Ser B Phys Biol Sci. 2010 May 11; 86(5): 484--493. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3108295/9.Igor E. Konstantinov, Nicolai Mejevoi, Nikolai M. Anichkov. "Nikolai N. Anichkov and His Theory of Atherosclerosis." Tex Heart Inst J. 2006; 33(4): 417--423. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1764970/10.Steinberg D, Gotto AM Jr. "Preventing coronary artery disease by lowering cholesterol levels: fifty years from bench to bedside." JAMA 1999;282:2043--50. http://www.ncbi.nlm.nih.gov/pubmed/1059138711."Scientific Report of the 2015 Dietary Guidelines Advisory Committee." health.gov. (Accessed 14 Mar 2015.) http://www.health.gov/dietaryguidelines/2015-scientific-report/12.Song TJ, Cho HJ, Chang Y, et al. "Low-density-lipoprotein particle size predicts a poor outcome in patients with atherothrombotic stroke." J Clin Neurol. 2015 Jan;11(1):80-6. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302183/13.Karim Harchaoui, Wim van der Steeg, Erik Stroes, et al. "Value of Low-Density Lipoprotein Particle Number and Size as Predictors of Coronary Artery Disease in Apparently Healthy Men and Women : The EPIC-Norfolk Prospective Population Study." Journal of the American College of Cardiology. Volume 49, Issue 5, 6 February 2007, Pages 547--553. http://www.sciencedirect.com/science/article/pii/S073510970602863414.Sabatine, Marc S., Giugliano, Robert P., Wiviott, Stephen D., et al. "Efficacy and Safety of Evolocumab in Reducing Lipids and Cardiovascular Events." New England Journal of Medicine. March 15, 2015 http://www.nejm.org/doi/full/10.1056/NEJMoa1500858#t=articleResults

How To Fight Fat With Fat By Pierre Tardif October 16, 2014 Categories: Featured - Home Page, Health & Wellness, Our LivesBeware: Statin Drugs Can Actually Cause Diabetes November 28, 2011 By Dr. Mercola  | 244,523 viewsLow Cholesterol Leads to an Early Death Posted on January 30, 2014 by Sally Fallon Morell Print - PDF - EmailLow Cholesterol Leads to an Early Death: Evidence From 101 Scientific PapersBy David Evans This book is a sequel to Cholesterol and Saturated Fat Prevent Heart Disease: Evidence from 101 Scientific Papers by the same author (and given a Thumbs Up review in Wise Traditions, Summer 2013)Cholesterol and Saturated Fat Prevent Heart Disease by David Evans Posted on June 27, 2013 by Sally Fallon Morell • 1 CommentDifferences Between the Weston A. Price Foundation Diet and the Paleo Diet Posted on October 7, 2013 by Sally Fallon Morell -Eggs Don't Deserve Their Bad Reputation, Studies Show (Op-Ed) Katherine Tallmadge   |   August 30, 2013 08:49pm ETNORTH CAROLINA EGG ASSOCIATION Representing NC Farmers.  االنسولين زياده 2014ديسمبر، 6السبت، اضرارwww.diabetes.co.uk www.news-medical.net www.mayoclinic.org www.ncbi.nlm.nih.goCould Eating the Right Fats Save 1 Million Lives per Year? March 06, 2016 | 12,591 viewsHEALTH: Cholesterol: The big fat lie, plus how to prevent heart disease By SARAH STACEY FOR THE MAIL ON SUNDAY PUBLISHED: 00:02 GMT, 12 July 2015 | UPDATED: 00:04 GMT, 12 July 2015The CoQ10-Statin Secret Ronald Grisanti D.C., D.A.B.C.O., D.A.C.B.N., M.S. ttp://www.functionalmedicineuniversity.com/statin-CoQ10.pdfThomas S. R., Neuzil J., Stocker R, Inhibition of LDL oxidation by ubiquinol-10. A protective mechanism of coenzyme Q in atherogenesis? Mol Asp Med, 18 (suppl.): s 85-103, 1997

Bargossi AM, Battino M, Gaddi A, et at. Exogenous CoQ10 preserves plasma ubiquinol levels in patients treated with 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors, Internal J Clin Lab Res, 24: 171-6, 1994Fuke C, Krikorian, SA, Couris RR, Coenzyme CoQ10: A review of essential functions and clinical trials, Pharmacist, 28-41, Oct 2000Langsjoen PH, Langsjoen AM, Coenzyme Q10 in cardiovascular disease with emphasis on heart failure and myocardial ischaemia, Asia Pacific Heart J ,7; 3: 160-168, 1998Langsjoen PH, et al, Treatment of statin adverse effects with supplemental coenzyme Q10 and statin drug discontinuation, BioFactors, 25 (1-4): 147-52, 2005Langsjoen PH, et al, The clinical use of HMG CoA-reductase inhibitors and the associated depletion of coenzyme Q10. A review of animal and human publications, BioFactors, 18 (1-4): 101-11, 2003Mabuchi H, et al, Reduction of serum ubiquinol-10 and a ubiquinone-10 levels by atorvastatin in hypercholesterolemia, patients, J Atheroscler Thromb, 12; 2:111-19, 2005Lamperti C, Muscle, coenzyme Q10 level in statin-related myopathy, Arch Neurol, 62; 11: 1109-12, Nov 2005Mortensen AS, et al, Coenzyme Q10: clinical benefits with biochemical correlates suggesting a scientific breakthrough in the management of chronic heart failure, Int J Tissue React, 12; 3: 155-62, 1990Folkers K, Langsjoen P, Tamagawa H, Lovastatin decreases coenzyme levels in humans, Proc Nall Acad Sci USA, 1990; 87:8931-34Bliznakov EG, Wilkins DJ, Biochemical and clinical consequences of inhibiting coenzyme Q10 biosynthesis by lipid-lowering HMG COA reductase inhibitors (statins): a critical overview, Advances in Therapy, 15; 4:219-28, Jul/Aug 1998Ghirlanda G, Oradei A, Manto A, et al, Evidence of plasma CoQ 10-lowering effect of HMG-CoA reductase inhibitors: a double-blind, placebo-controlled study, J Clin Pharmacol, 33: 226-29, 1993Willis RA. Folkers K, Tucker JL, Tamagawa H., et al., Lovastatin decreases coenzyme Q levels in rats, Proc Nat Acad Sci USA, 87: 8928-30. 1990

Folkers K, Langsjoen P, et al, Lovastatin decreases coenzyme Q10 levels in humans, Proc Nat Acad Sci USA, 87:8931-4, 1990Bliznakov EG, Lipid-lowering to drugs (statins), cholesterol, and coenzyme Q10. The Baycol case-¬-a modern Pandora's box, Biomed Pharmacother, 56:56-9, 2002Jameson S, Statistical data support prediction of death within six months on low levels of coenzyme Ql0 andmyculturedpalate.com/2012/09/25/cholesterol-the-unsung-antioxidant/Heart Disease: Cholesterol Is Not the Real Enemy 12-31-2015 Lorie Johnson

Cholesterol Myth: What Really Causes Heart Disease? 12-26-2012 Lorie JohnsonThe Diet-Heart Myth: Cholesterol and Saturated Fat Are Not the Enemy on APRIL 19, 2013 by CHRIS KRESSER The Real Roots of Heart Disease? How to Prevent Heart Disease – Eat More Cholesterol? wellnessmama.com › Blog › HealthSaturated fat's role in heart disease is a myth, says heart specialist Written by Catharine Paddock PhDLast updated: Thu 15 May 2014 email 4.51253SHARE14New Science Destroys the Saturated Fat Myth July 27, 2014 By Dr. Mercola

Statin - Wikipedia, the free encyclopediahttps://en.wikipedia.org/wiki/StatinSide effects of statins include muscle pain, increased risk of diabetes mellitus, and .....The

most serious form of myopathy, rhabdomyolysis, can damage the  ...You visited this page on 2/16/16.

The Grave Dangers of Statin Drugs—and the Surprising Benefits of Cholesterol BY ANH-USA ON JULY 14, 2015

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