Maintain your Methods, Prolong your Helium SupplyProlong your Helium Supply, and Save Your Budget with an Innovative Helium Solution

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Existing Ways to Tackle the Helium Supply Shortage

• Migrate to H2 carrier gas

• Switch over to nitrogen when the GC or GC-MS is not runningg

• Reduce the split ratio (and amount injected) during theamount injected) during the split time of the split injection

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Limitations of the Existing Approaches

• Migrate to hydrogen carrier gas• Safety concerns• Method translation• Reduced sensitivity• QA/AC adjustments

• Switch over to nitrogen when the GC or GC-MS is not running

• Reduce the split ratio (and amount injected) during the split time of the split injectiontime of the split injection• Not applicable to splitless• Accuracy may be affected with

smaller-volume injections

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j

The Helium Saver

Th l i Th S i ifi ™ I C H li SThe revolutionary Thermo Scientific™ Instant Connect Helium Saver Module for chromatographers seeking freedom from the helium supply crisis, offers a GC & GC-MS instrument lifetime helium carrier gas solution while keeping existing methodology Unlike others the Heliumsolution while keeping existing methodology. Unlike others, the Helium Saver is a module that is always ready and works while your instrument is running, as well as when it is idle, providing up to 14 years of GC & GC-MS operation from a single helium cylinderMS operation from a single helium cylinder.

• Maintain your Methods• Prolong your Supply• Save your Budget

www.thermoscientific.com/heliumsaver

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Instant Connect Modularity

• Modularity makes the Thermo Scientific™ TRACE™ 1300 GC a future-proof GC platform• New modules are compatible with existing TRACE 1300 Series GCs• User-installable: no service engineer, special training/tools required• Swap modules for continuous operations• Tailor instrument configuration to workloadTailor instrument configuration to workload • Quickly install injector/detector modules• Every module is self-sufficient• Reduce capital investments• Reduce capital investments• Eliminate downtime

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Helium Saver Enables a Cylinder of Helium to Last…

3.5 years continuously used 24/7/365 for GC-MS analysis5.4 years shutting Helium off or to N2 during weekends

10.5 years shutting Helium off or to N2 overnight (8 hr day)14 6 years shutting Helium off or to N on weekends and overnight14.6 years shutting Helium off or to N2 on weekends and overnight

For a Thermo Scientific™ TRACE 1300 Series GC, ISQ™ Series GC-MS and TSQ™ 8000 GC-MS/MSISQ Series GC-MS and TSQ 8000 GC-MS/MS

with the Helium Saver Module,it means this could be the last and only helium cylinder that

ill b d d f th lif ti f th i t twill be needed for the lifetime of the instrument

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Helium Saver Module ExampleEPA 8270 • Example: U.S. EPA Method 8270

(semi-volatiles analysis with GC-MS)• Total Analysis Time: 25 minutes

A d th Cl k A l D 57

EPA 8270GC Flow Conditions Standard

He carrier gas flow mL/min 1H li fl L/ i 60 • Around the Clock Analyses per Day: 57

Helium cylinder life time was extended from 5 months to 3 5 years

He split flow  mL/min 60Gas saver flow  mL/min 20Gas saver on min 3Purge flow  mL/min 5 extended from 5 months to 3.5 years

of continous uninterrupted use

Standard Helium Saver

Run time min 25He volume in cylinder  L 7,300Runs per Day 57He cylinder cost USD $300

He Consumption Consumption

Daily He Usage Liters 46.56  5.76He Cylinder Life Days 157 1 267

N2 cylinder cost USD $60

Helium Savings: 7 times He Cylinder Life Days 157 1,267Daily N2 Usage Liters 0 40.8N2 Cylinder Life Days 0 179

T t l A l C t $688 $205

g

(continuous uninterrupted use)

Monetary Savings: 3 times

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Total Annual Cost $688 $205Total Savings $483

Helium Saver Module vs. Conventional SSL

Helium Saver Module Conventional SSLContains the SSL as a sub-

system Industry standard injector

U tl th th d U d f > 80% th dUses exactly the same methods Used for > 80% methods

Preserves your methods and saves helium Wastes most of the heliumand saves helium

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Helium Saver vs. Conventional SSL: Rt Unchanged

Helium Saver He column flowN2 split and septum purge

C10 C11 C12

C13C14 C15

C16C17 C18C19 C20

C21C22

C23C24 C25

septum purge

SSLC10 C11 C21 C23 SSL Only He supplied

C16

C10 C11 C12C13

C14 C15 C17 C18C19 C20

C21C22

C23C24

C25

Splitless 1 uL30 m, 0.25 mm ,0.25 µm Thermo Scientific™ TRACE TR5 Column50 ˚ to 300 ˚C at 10 C/min

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CF 1 mL/minFID at 300 °C

Helium Saver: High Boiling Compounds Transfer

ComponentAbsolute  Peak 

Areas Recovery (%) *C14

C16C18

Complete recovery of high boiling compounds

Component Areas(counts) (%) *

nC10 2498258 100.3nC12 2457224 98.7nC14 2550661 102.4nC16 2504229 100.6

C10C32

C12

C36

C14

C38C40

C18

C34C20

C28C22 C30C24

C26

nC18 2484007 99.8nC20 2489876 100.0nC22 2482628 99.7nC24 2455417 98.6nC26 2409871 96.8nC28 2438442 97.9nC30 2469831 99.2nC32 2412554 96.9nC34 2472760 99.3nC36 2422105 97.3nC38 2394975 96.2nC40 2349780 94.4

Splitless 1 uL7 m, 0.32 mm ID,0.25 µm TRACE TR5 Column60 to 320 C at 10 C/minCF 2 mL/min

* nC20 internal standard reference

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CF 2 mL/minHelium Saver SSL and FID at 340 C

EPA Method 8270 Calibration Curves R2 Results

0 995

1.000

SSL Helium Saver Average: 0.998

0.985

0.990

0.995

Compound Name SSL Helium SaverN‐Nitrosodimethylamine 0.99852 0.99871

0.975

0.980

0.985 yPyridine 0.99831 0.99855Phenol 0.99843 0.99722Aniline 0.99846 0.99813Phenol, 2‐chloro‐ 0.99847 0.99743N nitrosodi n propylamine 0 99811 0 99808

0.965

0.970

N‐nitrosodi‐n‐propylamine 0.99811 0.99808Phenol, 2‐nitro‐ 0.99838 0.99859Phenol, 2,4‐dichloro‐ 0.99763 0.99937p‐Chloroaniline 0.99901 0.99875Phenol, 4‐chloro‐3‐methyl‐ 0.99561 0.99660

0.955

0.960Hexachlorocyclopentadiene 0.99541 0.99856Phenol, 2,4,6‐trichloro‐ 0.99723 0.99948Phenol, 2,4,5‐trichloro‐ 0.99609 0.998932‐Nitroaniline 0.99774 0.99915Dimethyl phthalate 0 99820 0 99757

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0.950Dimethyl phthalate 0.99820 0.997572,6‐dinitrotoluene 0.99702 0.99920

Helium Saver Technology: Revolutionary Approach

Innovative and Unique Features and Benefits• Up to 14 years of one helium cylinder life time

• Always saves – works during analytical run and idle time

• Always ready – no switch-back equilibration time

• Change septum and liner without GC or MS cooling down

• Can maintain existing methods

• Helium Saver Technology is covered by U.S. Patent 8,371,152

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How Long Can One Helium Cylinder Last in YOUR Lab?

Use our calculator to find out how much the Helium Saver Module can help your lab. p yEnter your working parameters and discover the following:

• How long one cylinder of helium can last in your laby

• How much budget you can save on helium supplies over the lifetime of your GC or GC-

www thermoscientific com/heliumsaver

yMS instrument

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www.thermoscientific.com/heliumsaver

Interested in Learning More?

Visit the website address below for more information:

• Determine your potentialDetermine your potential helium savings with our online calculator

• Download a technical article• Download a technical article that outlines the helium supply shortage and solution

Vi bi h• View a webinar that discusses this information in detail

www thermoscientific com/heliumsaver

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www.thermoscientific.com/heliumsaver

Thank You for Your Attention!

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