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    Chemistry & BiochemistryChapters 2 & 3

    Honors Biology

    Mrs. Gutierrez

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    Why studychemistry in

    a biologyclass?

    Even the most

    basic units oflife, cells , aremade of smallerand smallersubunits

    The structureand function ofall living thingsare governed bythe laws ofchemistry

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    What is Chemistry?

    The study of the composition, structure, properties, and reactions of a substance.

    All life processes involve chemical changes. Digestion Reproduction Growth

    Respiration

    Once chemical changes are understood, life processes can be better understood.

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    matter energy

    atoms mass

    elements

    92109

    molecule

    compound

    structure

    proton neutron electron

    nucleus isotope ion

    hydrogen

    pH

    acid base

    kineticheat

    movement Activationenergy

    reactions

    potential

    position

    stored

    battery ATP

    chemical

    bonds

    ionic

    covalenthydrogen

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    What is pH?

    pH stands for the potential/power of thehydrogen ion (H +)

    pOH is the potential/power of thehydroxide ion (OH -)

    pH and pOH add up to14 Ex: if the pOH of a

    solution is 7, what is the pH?

    A pH of 7 is considered

    neutral

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    http://www.johnkyrk.com/pH.html

    pH scale quantified

    http://www.johnkyrk.com/pH.htmlhttp://www.johnkyrk.com/pH.htmlhttp://www.johnkyrk.com/pH.htmlhttp://www.johnkyrk.com/pH.html
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    pH Concentrations

    What type of a solution has a pH of 5? Acid

    Which is a stronger acid, pH 5 or pH 2? pH 2

    How much stronger? 103 or 1,000 times stronger The pH scale is logarithmic, each increment being a

    multiple of 10 The increments are then multiplied

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    Indicators indicate the concentration of a substance

    by color. Universal indicator is only one example.

    http://www.bgfl.org/bgfl/custom/resources_ftp/client_ftp/ks3/science/acids/index.htmhttp://www.bgfl.org/bgfl/custom/resources_ftp/client_ftp/ks3/science/acids/index.htm
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    ttp: www. g .org g customresources_ftp/client_ftp/ks3/scien

    ce/acids/index.htm Read the Help section to review Chose Litmus Reactions Type your FULL name Follow directions

    http://www.bgfl.org/bgfl/custom/resources_ftp/client_ftp/ks3/science/acids/index.htmhttp://www.bgfl.org/bgfl/custom/resources_ftp/client_ftp/ks3/science/acids/index.htmhttp://www.bgfl.org/bgfl/custom/resources_ftp/client_ftp/ks3/science/acids/index.htmhttp://www.bgfl.org/bgfl/custom/resources_ftp/client_ftp/ks3/science/acids/index.htmhttp://www.bgfl.org/bgfl/custom/resources_ftp/client_ftp/ks3/science/acids/index.htmhttp://www.bgfl.org/bgfl/custom/resources_ftp/client_ftp/ks3/science/acids/index.htm
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    Reaction of Various Materials to

    pH & Litmus PapersMaterialTested

    Reaction toRed Litmus

    Reaction toBlue Litmus

    pH accordingto pH paper

    HCl

    NaOH

    H2O

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    Other ways of measuring pH

    pH meter Hand-held device

    pH probe Uses a computer

    interface

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    pH Lab

    You will be using atechnique called titration

    An acid or base will be placed in a buret andslowly added to the testsolution Water Buffer Cell homogenate

    The computer will assistin recording any changesin pH

    Acid or

    base

    Test soln.

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    Chemical Buffers

    Chemical substances thatneutralize small amountsor either acid or base

    added to a solution BUFFERS DO NOT

    NECESSARILY NEUTRALIZE THESOLUTION TO A PH 7!

    Ex: stomach acid remainsat a pH of 2 regardless ofwhether you ingest acidicor basic substances

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    Application of Buffers

    Chemicalreactions willonly occurnormally in asystem thatresists a changein pH

    This is part of a process knownas homeostasi s

    The pH of many living things tends to be around neutral.

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    Monomer vs. Polymer Mono = 1 A monomer is the

    basic building block

    poly = many A polymer is made up

    of many monomers

    How do the 2boxcars jointogether to form

    a long train?

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    Dehydration Synthesis or

    Condensation Reaction

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    Condensation/Hydrolysis

    Demonstration http://www.tvdsb.on.ca/westmin/science/sbi

    oac/biochem/condense.htm

    http://www.tvdsb.on.ca/westmin/science/sbioac/biochem/condense.htmhttp://www.tvdsb.on.ca/westmin/science/sbioac/biochem/condense.htmhttp://www.tvdsb.on.ca/westmin/science/sbioac/biochem/condense.htmhttp://www.tvdsb.on.ca/westmin/science/sbioac/biochem/condense.htm
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    Note: Glucose and fructose are isomers

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    Review

    Monosaccharide #2Monosaccharide #1

    Disaccharide

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    Formation of a polysaccharide

    http://science.nhmccd.edu/biol/dehydrat/dehydrat.html

    http://www.tvdsb.on.ca/westmin/science/sbioac/biochem/condense.htm

    http://science.nhmccd.edu/biol/dehydrat/dehydrat.htmlhttp://science.nhmccd.edu/biol/dehydrat/dehydrat.htmlhttp://www.tvdsb.on.ca/westmin/science/sbioac/biochem/condense.htmhttp://www.tvdsb.on.ca/westmin/science/sbioac/biochem/condense.htmhttp://www.tvdsb.on.ca/westmin/science/sbioac/biochem/condense.htmhttp://www.tvdsb.on.ca/westmin/science/sbioac/biochem/condense.htmhttp://science.nhmccd.edu/biol/dehydrat/dehydrat.htmlhttp://science.nhmccd.edu/biol/dehydrat/dehydrat.html
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    LipidsType of

    Compound

    Examples Elements Subunit

    (monomer)

    Functions

    Triglycerides Fats,

    Oils

    Carbon,hydrogen,oxygen

    3 fatty acids and aglycerol

    Stored energy(9Cal/g), insulation,nerve impulses,

    protectionSecondary solvent ofcell

    Waxes Ear wax Same 1 fatty acid andalcohol chain

    Protection,waterproofing

    Steroids Hormones,

    cholesterol

    Same Fused carbon rings Regulate chemical

    reactions

    Phospholipids Cellmembranes

    same 2 fatty acids and aglycerol

    Regulates what entersand leaves a cell

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    Formation of a Triglyceride

    http://www.tvdsb.on.ca/westmin/science/sbioac/biochem/triglyc.htm

    http://www.tvdsb.on.ca/westmin/science/sbioac/biochem/triglyc.htmhttp://www.tvdsb.on.ca/westmin/science/sbioac/biochem/triglyc.htmhttp://www.tvdsb.on.ca/westmin/science/sbioac/biochem/triglyc.htmhttp://www.tvdsb.on.ca/westmin/science/sbioac/biochem/triglyc.htm
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    P i

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    ProteinsType ofCompound

    Examples Elements Subunit(monomer)

    Functions

    Hemoglobin

    Carbon,hydrogen,oxygen,nitrogen

    Amino acid General function of a protein is building andrepair. (May be used asan energy source as alast resort (4Cal/g)?Binds gases in red

    blood cellsInsulin Same Same Regulates blood sugar

    levels

    Albumin Same Same Nourishing componentof egg whites

    Keratin Same Same Structural componentof hair, skin, and nails

    Enzymes Same Same Act as a catalyst byregulating chemical

    reaction rates

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    Formation of a polypeptide

    http://www.tvdsb.on.ca/westmin/science/sbioac/biochem/amino.htm

    http://www.tvdsb.on.ca/westmin/science/sbioac/biochem/amino.htmhttp://www.tvdsb.on.ca/westmin/science/sbioac/biochem/amino.htmhttp://www.tvdsb.on.ca/westmin/science/sbioac/biochem/amino.htmhttp://www.tvdsb.on.ca/westmin/science/sbioac/biochem/amino.htm
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    Enzymes

    Most enzyme are proteins Three characteristics

    Reusable Specific Catalyst (lower the activation energy (E a)of a

    reaction) http://www3.fhs.usyd.edu.au/bio/homeostasis/C

    ontrol_Systems.htm (read from theintroduction to the definition of homeostasis)

    ttp: www m e com p yssc c

    http://www3.fhs.usyd.edu.au/bio/homeostasis/Control_Systems.htmhttp://www3.fhs.usyd.edu.au/bio/homeostasis/Control_Systems.htmhttp://images.google.com/imgres?imgurl=http://sps.k12.ar.us/massengale/images/lockandkeymodel.gif&imgrefurl=http://sps.k12.ar.us/massengale/cell_respiration_bi.htm&h=94&w=81&sz=3&tbnid=AkaohPO76zcJ:&tbnh=75&tbnw=64&hl=en&start=36&prev=/images%3Fq%3Denzyme%2Bsubstrate%2Bcomplex%26start%3D20%26svnum%3D10%26hl%3Den%26lr%3D%26sa%3DNhttp://www3.fhs.usyd.edu.au/bio/homeostasis/Control_Systems.htmhttp://www3.fhs.usyd.edu.au/bio/homeostasis/Control_Systems.htmhttp://www.mhhe.com/physsci/chemistry/essentialchemistry/flash/activa2.swfhttp://www.mhhe.com/physsci/chemistry/essentialchemistry/flash/activa2.swf
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    ttp: www.m e.com p yssc cemistry/essentialchemistry/flash/

    activa2.swf Short video clip of exothermic reactions.

    http://www.mhhe.com/physsci/chemistry/essentialchemistry/flash/activa2.swfhttp://www.mhhe.com/physsci/chemistry/essentialchemistry/flash/activa2.swfhttp://www.mhhe.com/physsci/chemistry/essentialchemistry/flash/activa2.swfhttp://www.mhhe.com/physsci/chemistry/essentialchemistry/flash/activa2.swfhttp://www.mhhe.com/physsci/chemistry/essentialchemistry/flash/activa2.swfhttp://www.mhhe.com/physsci/chemistry/essentialchemistry/flash/activa2.swf
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    2H 2O2 2H 2O + O 2

    catalase

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    Catalase An enzyme found in any

    living tissue, plant oranimal

    Catalase works best underconstant conditions(homeostasis) oftemperature and pH

    Predict what the graphwould look like if the

    liver, containing catalase,is Boiled Acidified

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    Type ofcompound

    Examples Elements Subunits(monomers)

    Functions

    Nucleic Acids DNA

    RNA

    Carbon,hydrogen,oxygen,nitrogen,

    phosphorus

    Nucleotide Stores geneticinformation formaking proteins

    Directlyinvolved in

    proteinsynthesis

    Water Ice, liquidwater,vapor

    Hydrogen,oxygen

    H2O Primary solventof the cell

    -polar

    -cohesive

    -adhesive

    ttp: programs nort an co ege

    http://programs.northlandcollege.edu/biology/Biology1111/animations/hydrogenbonds.htmlhttp://programs.northlandcollege.edu/biology/Biology1111/animations/hydrogenbonds.html
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    ttp: programs.nort an co ege.edu/biology/Biology1111/animati

    ons/hydrogenbonds.html Short video clip about waters polarity and

    hydrogen bonding properties.

    http://programs.northlandcollege.edu/biology/Biology1111/animations/hydrogenbonds.htmlhttp://programs.northlandcollege.edu/biology/Biology1111/animations/hydrogenbonds.htmlhttp://programs.northlandcollege.edu/biology/Biology1111/animations/hydrogenbonds.htmlhttp://programs.northlandcollege.edu/biology/Biology1111/animations/hydrogenbonds.htmlhttp://programs.northlandcollege.edu/biology/Biology1111/animations/hydrogenbonds.htmlhttp://programs.northlandcollege.edu/biology/Biology1111/animations/hydrogenbonds.html
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