2000 multi-membered O,S-heterocycles

multi-membered O,S-heterocycles (O or S ring members)R 0691

38 - 178Synthesis of Tricyclic Compounds as Steroid 5α-Reductase Inhibitors.— Ongoing research leads to the synthesis of a novel series of compounds, e.g.(III). The biological activity is similar to that of the racemate of ONO-3805(some yields not given). — (TAKAMI, HITOSHI; NONAKA, HIROMI;KISHIBAYASHI, NOBUYUKI; ISHII, AKIO; KASE, HIROSHI; KUMAZAWA,TOSHIAKI; Chem. Pharm. Bull. 48 (2000) 4, 552-555; Pharm. Res. Lab.,Kyowa Hakko Kogyo Co., Ltd., Sunto, Shizuoka 411, Japan; EN)

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