2002 biochemical syntheses, microbiological syntheses

biochemical syntheses, microbiological synthesesO 0035

29 - 049Enantioselective Reduction of Dialkyl 4-(Dialkoxyphosphoryl)-3-oxobutanoates by Baker’s Yeast. — Yeast-mediated bioreduction ofdialkyl 4-(dialkoxyphosphoryl)-3-oxobutanoates (III), obtained by an improvedmethod, provides the corresponding hydroxybutanoates (IV) (8 examples)in moderate to good yield and enantioselectivity. — (YUAN, CHENGYE;WANG, KE; LI, JINFENG; LI, ZUYI; Heteroat. Chem. 13 (2002) 2, 153-156;Shanghai Inst. Org. Chem., Chin. Acad. Sci., Shanghai 200032, Peop. Rep.China; EN)

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