cheminform abstract: case study of a γ-butyrolactone alkylation with 1,3-dimethyl-2-imidazolidinone...

2002 furan derivatives furan derivatives R 0060 18 - 108 Case Study of a γ-Butyrolactone Alkylation with 1,3-Dimethyl- 2-imidazolidinone as a Promoter. — Ecologically friendly reagent 1,3-dimethyl-2-imidazolidinone is used in stoichiometric amounts to promote eﬀectively the rate of lactone alkylation, therefore minimizing dialkylation reaction. The present new method is also applicable for large scale preparations. — (LI, BRYAN; BUZON, RICHARD A.; CASTALDI, MICHAEL J.; Org. Process Res. Dev. 5 (2001) 6, 609-611; Groton Lab., Pﬁzer Global Res. Dev., Groton, CT 06340, USA; EN) 1

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Page 1: ChemInform Abstract: Case Study of a γ-Butyrolactone Alkylation with 1,3-Dimethyl-2-imidazolidinone as a Promoter

2002 furan derivatives

furan derivativesR 0060

18 - 108Case Study of a γ-Butyrolactone Alkylation with 1,3-Dimethyl-2-imidazolidinone as a Promoter. — Ecologically friendly reagent1,3-dimethyl-2-imidazolidinone is used in stoichiometric amounts to promoteeffectively the rate of lactone alkylation, therefore minimizing dialkylationreaction. The present new method is also applicable for large scale preparations.— (LI, BRYAN; BUZON, RICHARD A.; CASTALDI, MICHAEL J.; Org.Process Res. Dev. 5 (2001) 6, 609-611; Groton Lab., Pfizer Global Res. Dev.,Groton, CT 06340, USA; EN)

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METHODOLOGY Ecientiterativevirtualscreening with … · 2018. 3. 1. · Ahmed et al. J Cheminform Page4of8 10contain‘high-scoring’ligands.eunassignedbin3is excludedfromtraining.Figure

Database fingerprint (DFP): an approach to represent ... · Fernández‑de Gortari et al. J Cheminform DOI 10.1186/s13321‑017‑0195‑1 PRELIMINARY COMMUNICATION Database fingerprint

RESEARCHARTICLE Assessingtheinformationcontent ......Rodríguez‑Pérezet al. J Cheminform Page6of14 whichyieldedmedianMCCvaluesof0.67(IFP_85) and0.63(EFCP_folded).us,inhibitorswithbinding

The stereoselective synthesis of the butyrolactone-bridged

Investigating Imidazolidinone Catalysts: …my first day in lab when Tehshik Yoon stopped in front of the shelves that separated our benches, cocked his head, and smiled. To anyone

Effect of g-ethyl-g-phenyl-butyrolactone (EFBL ...acta.pharmaceutica.farmaceut.org/21517.pdf · 217 L. A. V. Rasgado et al.: Effect of g-ethyl-g-phenyl-butyrolactone (EFBL), anticonvulsant

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Case Report Management of Gamma-Butyrolactone Dependence

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Gamma-butyrolactone (GBL)

Pre-Review of gamma-Butyrolactone - WHO · 35th ECDD (2012) Agenda item 5.4 Gamma-butyrolactone (GBL) 3 Acknowledgements This report has been drafted under the responsibility of the