cheminform abstract: asymmetric synthesis of pyrrolo[2,1-a]isoquinoline derivatives by 1,3-dipolar...

2

ChemInform 2011, 42, issue 32 © 2011 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim Fused pyridine derivatives R 0450 DOI: 10.1002/chin.201132144 Asymmetric Synthesis of Pyrrolo[2,1-a]isoquinoline Derivatives by 1,3-Dipolar Cycloadditions of Stabilized Isoquinolinium N-Ylides with Sulfinyl Dipolaro- philes. — The title reaction allows an efficient and enantioselective access to highly functionalized pyrroloisoquinoline derivatives of biological interest. — (GARCIA RUANO*, J. L.; FRAILE, A.; MARTIN, M. R.; GONZALEZ, G.; FAJARDO, C.; MARTIN-CASTRO, A. M.; J. Org. Chem. 76 (2011) 9, 3296-3305, http://dx.doi.org/10.1021/jo200191c ; Dep. Quim. Org., Univ. Auton., Cantoblanco, E-28049 Madrid, Spain; Eng.) — Jannicke 32- 144

Upload: jose-luis-garcia-ruano

Post on 11-Jun-2016

213 views

Category:

Documents

0 download

Report

Download

Embed Size (px):

TRANSCRIPT

Page 1: ChemInform Abstract: Asymmetric Synthesis of Pyrrolo[2,1-a]isoquinoline Derivatives by 1,3-Dipolar Cycloadditions of Stabilized Isoquinolinium N-Ylides with Sulfinyl Dipolarophiles

Fused pyridine derivativesR 0450 DOI: 10.1002/chin.201132144

Asymmetric Synthesis of Pyrrolo[2,1-a]isoquinoline Derivatives by 1,3-Dipolar Cycloadditions of Stabilized Isoquinolinium N-Ylides with Sulfinyl Dipolaro-philes. — The title reaction allows an efficient and enantioselective access to highly functionalized pyrroloisoquinoline derivatives of biological interest. — (GARCIA RUANO*, J. L.; FRAILE, A.; MARTIN, M. R.; GONZALEZ, G.; FAJARDO, C.; MARTIN-CASTRO, A. M.; J. Org. Chem. 76 (2011) 9, 3296-3305, http://dx.doi.org/10.1021/jo200191c ; Dep. Quim. Org., Univ. Auton., Cantoblanco, E-28049 Madrid, Spain; Eng.) — Jannicke

32- 144

ChemInform 2011, 42, issue 32 © 2011 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim

Page 2: ChemInform Abstract: Asymmetric Synthesis of Pyrrolo[2,1-a]isoquinoline Derivatives by 1,3-Dipolar Cycloadditions of Stabilized Isoquinolinium N-Ylides with Sulfinyl Dipolarophiles

ChemInform 2011, 42, issue 32 © 2011 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim

CF3SO2X (X = Na, Cl) as reagents for trifluoromethylation ... · CF3SO2X (X = Na, Cl) as reagents for trifluoromethylation, trifluoromethylsulfenyl-, -sulfinyl- and -sulfonylation

POLYCYCLIC PYRROLO-THIAZOLE SYSTEMS WITH BIOLOGICAL ACTIVITY Thesis... · like molecules, which allows achieving new pharmacological profile, action, toxicity lowering. For example,

Pyrrolo[1,2-a]quinazolines. Synthesis and biological activity.pdf

Indolizines and pyrrolo[1,2-c]pyrimidines decorated with a … · 2015. 6. 26. · 1079 Indolizines and pyrrolo[1,2-c]pyrimidines decorated with apyrimidine and a pyridine unit respectively

Asymmetric Synthesis Using Chiral Sulfinyl Groups 958... · Asymmetric Synthesis Using Chiral Sulfinyl Groups Yiqian Lian Department of Chemistry Michigan State University

ChemInform Sheet A4on chemo-, regio-, and stereo-selective reactions. The RefLib database is included with CIRX and provides reactions abstracted from Theilheimer’s Synthetic Methods

Lei Wu, Jing Sun, Chao-Guo Yan* Supporting Information · 1 Facile Synthesis of spiro[indoline-3,3'-pyrrolo[1,2-a]quinolines] and spiro[indoline-3,1'-pyrrolo[2,1-a]isoquinolines]

Open Access Programming langage in chemiy: a eie of HTML5 ... · Theien J Cheminform Page 3 of 19 HTML5 econtentweviewontheInternetismadepossiblebya unionofseveraltechnologies,mainlyHypertextMarkup

Electronic Supplementary Information (ESI) · 1 Electronic Supplementary Information (ESI) for First synthesis of an aziridinyl fused pyrrolo[1,2-a]benzimidazole and toxicity evaluation

MER: a shell script and annotation server for minimal named ......Couto and Lamurias J Cheminform Page 5 of 10 common,sandswesempiricallysfoundsthatsmostsofsthestwo-charactersmatchesswereserrors

RESEARCHARTICLE OpAccess ......Jiangiet al. J Cheminform Pagej2jofj26 playerindrugabsorption,distribution,metabolism, excretion,andtoxicity(ADMET)[5, 6],andhasalsobeen

Research Paper Pyrrolo [3,4-b]-quinolin-9-amine compound ...€¦ · Research Paper Pyrrolo [3,4-b]-quinolin-9-amine compound FZU-0038-056 suppresses triple-negative breast cancer

Supporting Information for - Royal Society of Chemistry · S‐1 Supporting Information for Diastereo- and Enantioselective Construction of Biologically Important Pyrrolo[1,2-a]indole

Lei Tan, Yu Xia Department of Chemistry Purdue University€¦ · Lei Tan, Yu Xia Department of Chemistry Purdue University 1. Introduction • Sulfinyl radical (-SO•) – Photolysis

SULFINYL CHLORIDES AS A SOURCE OF · PDF fileSULFINYL CHLORIDES AS A SOURCE OF ENANTIOENRICHED ... Project Goals ... elevated temperatures5 The mechanism of this thermal racemization

Open Access CSgator:kanjintegratedkwebkplatformk forjcompoundksetkanalysis · 2019. 3. 4. · Parkjet al. J Cheminform Pagek6kofk8 currentlackofenoughcompound-targetdataevenafter

Design of N-Sulfinyl Homoallylic Amines as Novel ... · Design of N-Sulfinyl Homoallylic Amines as Novel Sulfinamide-Olefin Hybrid Ligands for Asymmetric Catalysis: Application in

1, 2, 8, 8A-tetrahydrocyclopropa (c) pyrrolo (3, 2-e)-indol-4-(5H

METHODOLOGY Molecularstructuresenumeration and ......Koch et al. J Cheminform Page5of17 changing4bonds,sinceweaimtondminimaltransfor - mations.Letuscall a 13 and a 24 thetwoﬁxedbonds,with

Privileged Scaffolds or Promiscuous Binders: A Glance of Pyrrolo

Classification System for Solid Supports Used ... - FIZ CHEMIE › fileadmin › user_upload › Cheminform › Spore › _… · FIZ CHEMIE BERLIN - 5 (23) - The remainder of the

Database fingerprint (DFP): an approach to represent ... · Fernández‑de Gortari et al. J Cheminform DOI 10.1186/s13321‑017‑0195‑1 PRELIMINARY COMMUNICATION Database fingerprint

Supporting Information for deprotection of sulfinyl group · Supporting Information ... 2.2 Experiments for elaborating the proposed pathway ... 2.2.2 Experiment with n-Bu3SnH

Single-Molecule Fluorescence Using Nucleotide Analogs: A ...kimmon.businesscatalyst.com/datasheets/publications/6_Single-Mol… · pyrrolo-C (PyC), have been extensively used to study

GPURFSCREEN: a GPU based virtual screening tool …people.cse.nitc.ac.in/jayaraj/files/gpurfscreen...Jayaraj et al. J Cheminform DOI 10.1186/s13321-016-0124-8 SOFTWARE GPURFSCREEN:

Synthesis of a Pyrrolo[1,4]Benzodiazepinequinone Ricardo a. Tapia,Cesar r. Centella and Jaime a. Valderrama

Nucleophilic and electrophilic cyclization of N-alkyne ... · substituted pyrrole derivatives: Synthesis of pyrrolopyrazinone, pyrrolotriazinone, and pyrrolo-oxazinone moieties Işıl

Statistical principle-based approach for gene and protein ... · Lai et al. J Cheminform Page 2 of 9 tobiologicaldatabaserecords.Intheabovecases,“A2A” isasubtypeof“adenosinereceptor”.erefore“A2A

Certificate of Analysis-4-(1H-pyrazol-4-yl)-7-((2-(trimethylsilyl)ethoxy) methyl)-7H-pyrrolo[2,3-d]pyrimidine 941685-27-4 B15S0913 (1)

Electrochemica l studies of two pyrrolo[1,2 -c]pyrimidines · 2018. 6. 1. · M.-L. Tatu: Electrochemical studies of two pyrrolo[1,2-c]pyrimidines … 28 . Table 1. Investigated pyrrolo[1,2-c]pyrimidines

ChemInform Sheet A4 · 2013. 9. 13. · The ChemInform Reaction Library (CIRX) helps to deal with the enormous number of published reactions as it does not cover all information available

Synthetic Applications of Nitropyridine Derivatives · Preparation of novel pyridine fused trisheterocycles; pyrido[4,3 e]pyrrolo/ ... prepared by nitration of pyridines in a nitric

Open Access C S :kextractionkandjre-use(ability)k ... · Nguyenjet al. J Cheminform Pagek2kofk9 forthegenerationofcalculatedinformationandidenti-ers.AlthoughtherearesomealternativestoChemDraw,

5-amino-2, 6-substituted-7h-pyrrolo (2, 3-d) pyrimidines and related

BIOINFORMATICS Review …“.Jónsdóttir et al. Fig. 1. Number of papers in PubMed 1992–2004 containing the keywords ‘bioinformatics’ (top left), ‘chemoinformatics’ or ‘cheminform-atics’,