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CHINA

COMPLIANT

Naturethic BrownSlim is a cosmetic extract that helps change the function of adipocytes from fat storage to fat burning cells and also minimize de novo fat accumulation. It is made of two extracts from vegetable sources : Undaria pinnatifida extract (rich in fucoxanthin) and Garcinia Cambogia extract (rich in hydroxycitrate).

Undaria pinnatifida (Wakame) Extract

FAT-BURNING ACTIVATION

PRODUCT DESCRIPTIONINCI : WATER (AQUA), GLYCERIN, LECITHIN, GARCINIA CAMBOGIA FRUIT EXTRACT, UNDARIA PINNATIFIDA EXTRACT, XANTHAN GUM Additives : SODIUM BENZOATE, POTASSIUM SORBATE, TETRASODIUM GLUTAMATE DIACETATE.

Appearance : Orange to red

Solubility : Soluble in water

Formulation : It should be incorporated at the endof the formulation at a temperature <40ºC

Recommended dosage : 3.0 pH : 3.5 - 5.0

Fucoxanthin :Upregulates UCP1 gene

it redirects fat burning into heat Increases fatty acids breakdown

Lipolytic effect

CHEMICAL COMPOSITION

Garcinia Cambogia Extract

Hydroxycitrate :Essential for lipids metabolismInhibits (ACLY) ATP citrate lysate

that produces Acetyl-CoA in the cytosolPrevents de novo lipogenesis

(new fat synthesis)

CHEMICAL COMPOSITION

NO FAT ACCUMULATION SLIMMING EFFECT

****

****

6

Control

4

2

0

UCP

1 vs

Con

trol

0.00025 0.0005

BrownSlim (%)

In vitro. Technique: UCP1 expression analysed by RT-qPCRin Human Adipocytes. t = 24h

UCP1 Gene Expression

+35%

FAT BURNING (BROWN FAT) CELLS INDUCTION

IN VIVO STUDY - Placebo controlled

D 28

20

DAYSTHIGHSCELLULITE GRADE 1-2

(MÜLLER SCALE)

32 -52 YRS

3 % 28ACTIVE

TWICE A DAYANTI-CELLULITE EFFICACY UPON TREATMENT ON THIGHSTechnique : Measurements included weight, thigh circumference, clinical photography. 3D analysis of dimples with FOITS. 50 MHz high frequency evaluation of the epidermis and dermis.

IN ONLY

-1.6cm

UP TO

-9%

VOLUME REDUCTION

DIMPLE REDUCTION

+6.5%

DERMAL DENSITY

4WEEKS33ºC

33ºC

27ºC

27ºC

BrownSlimt = 0 D

BrownSlimt = 28 D

Placebot = 28D

BrownSlimt = 28D

HighertemperatureBrown FatActivated