Γcamkii shuttles ca2+/cam to the nucleus to trigger creb phosphorylation and gene expression huan...

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γCaMKII Shuttles Ca2+/CaM to the Nucleus to Trigger CREB Phosphorylation and Gene Expression Huan Ma, Rachel D. Groth, Samuel M. Cohen, John F. Emery, Boxing Li, Esthelle Hoedt, Guoan Zhang, Thomas A. Neubert, Richard W. Tsien Cell Volume 159, Issue 2, Pages 281-294 (October 2014) DOI: 10.1016/j.cell.2014.09.019 Copyright © 2014 Elsevier Inc. Terms and Conditions

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Page 1: ΓCaMKII Shuttles Ca2+/CaM to the Nucleus to Trigger CREB Phosphorylation and Gene Expression Huan Ma, Rachel D. Groth, Samuel M. Cohen, John F. Emery,

γCaMKII Shuttles Ca2+/CaM to the Nucleus to Trigger CREB Phosphorylation and Gene Expression 

Huan Ma, Rachel D. Groth, Samuel M. Cohen, John F. Emery, Boxing Li, Esthelle Hoedt, Guoan Zhang, Thomas A. Neubert, Richard W. Tsien 

Cell Volume 159, Issue 2, Pages 281-294 (October 2014)

DOI: 10.1016/j.cell.2014.09.019

Copyright © 2014 Elsevier Inc. Terms and Conditions

Page 2: ΓCaMKII Shuttles Ca2+/CaM to the Nucleus to Trigger CREB Phosphorylation and Gene Expression Huan Ma, Rachel D. Groth, Samuel M. Cohen, John F. Emery,

Figure 1

Cell 2014 159, 281-294DOI: (10.1016/j.cell.2014.09.019) Copyright © 2014 Elsevier Inc. Terms and Conditions

Page 3: ΓCaMKII Shuttles Ca2+/CaM to the Nucleus to Trigger CREB Phosphorylation and Gene Expression Huan Ma, Rachel D. Groth, Samuel M. Cohen, John F. Emery,

Figure 2

Cell 2014 159, 281-294DOI: (10.1016/j.cell.2014.09.019) Copyright © 2014 Elsevier Inc. Terms and Conditions

Page 4: ΓCaMKII Shuttles Ca2+/CaM to the Nucleus to Trigger CREB Phosphorylation and Gene Expression Huan Ma, Rachel D. Groth, Samuel M. Cohen, John F. Emery,

Figure 3

Cell 2014 159, 281-294DOI: (10.1016/j.cell.2014.09.019) Copyright © 2014 Elsevier Inc. Terms and Conditions

Page 5: ΓCaMKII Shuttles Ca2+/CaM to the Nucleus to Trigger CREB Phosphorylation and Gene Expression Huan Ma, Rachel D. Groth, Samuel M. Cohen, John F. Emery,

Figure 4

Cell 2014 159, 281-294DOI: (10.1016/j.cell.2014.09.019) Copyright © 2014 Elsevier Inc. Terms and Conditions

Page 6: ΓCaMKII Shuttles Ca2+/CaM to the Nucleus to Trigger CREB Phosphorylation and Gene Expression Huan Ma, Rachel D. Groth, Samuel M. Cohen, John F. Emery,

Figure 5

Cell 2014 159, 281-294DOI: (10.1016/j.cell.2014.09.019) Copyright © 2014 Elsevier Inc. Terms and Conditions

Page 7: ΓCaMKII Shuttles Ca2+/CaM to the Nucleus to Trigger CREB Phosphorylation and Gene Expression Huan Ma, Rachel D. Groth, Samuel M. Cohen, John F. Emery,

Figure 6

Cell 2014 159, 281-294DOI: (10.1016/j.cell.2014.09.019) Copyright © 2014 Elsevier Inc. Terms and Conditions

Page 8: ΓCaMKII Shuttles Ca2+/CaM to the Nucleus to Trigger CREB Phosphorylation and Gene Expression Huan Ma, Rachel D. Groth, Samuel M. Cohen, John F. Emery,

Figure 7

Cell 2014 159, 281-294DOI: (10.1016/j.cell.2014.09.019) Copyright © 2014 Elsevier Inc. Terms and Conditions

Page 9: ΓCaMKII Shuttles Ca2+/CaM to the Nucleus to Trigger CREB Phosphorylation and Gene Expression Huan Ma, Rachel D. Groth, Samuel M. Cohen, John F. Emery,

Figure S1

Cell 2014 159, 281-294DOI: (10.1016/j.cell.2014.09.019) Copyright © 2014 Elsevier Inc. Terms and Conditions

Page 10: ΓCaMKII Shuttles Ca2+/CaM to the Nucleus to Trigger CREB Phosphorylation and Gene Expression Huan Ma, Rachel D. Groth, Samuel M. Cohen, John F. Emery,

Figure S2

Cell 2014 159, 281-294DOI: (10.1016/j.cell.2014.09.019) Copyright © 2014 Elsevier Inc. Terms and Conditions

Page 11: ΓCaMKII Shuttles Ca2+/CaM to the Nucleus to Trigger CREB Phosphorylation and Gene Expression Huan Ma, Rachel D. Groth, Samuel M. Cohen, John F. Emery,

Figure S3

Cell 2014 159, 281-294DOI: (10.1016/j.cell.2014.09.019) Copyright © 2014 Elsevier Inc. Terms and Conditions

Page 12: ΓCaMKII Shuttles Ca2+/CaM to the Nucleus to Trigger CREB Phosphorylation and Gene Expression Huan Ma, Rachel D. Groth, Samuel M. Cohen, John F. Emery,

Figure S4

Cell 2014 159, 281-294DOI: (10.1016/j.cell.2014.09.019) Copyright © 2014 Elsevier Inc. Terms and Conditions

Page 13: ΓCaMKII Shuttles Ca2+/CaM to the Nucleus to Trigger CREB Phosphorylation and Gene Expression Huan Ma, Rachel D. Groth, Samuel M. Cohen, John F. Emery,

Figure S5

Cell 2014 159, 281-294DOI: (10.1016/j.cell.2014.09.019) Copyright © 2014 Elsevier Inc. Terms and Conditions

Page 14: ΓCaMKII Shuttles Ca2+/CaM to the Nucleus to Trigger CREB Phosphorylation and Gene Expression Huan Ma, Rachel D. Groth, Samuel M. Cohen, John F. Emery,

Figure S6

Cell 2014 159, 281-294DOI: (10.1016/j.cell.2014.09.019) Copyright © 2014 Elsevier Inc. Terms and Conditions

Page 15: ΓCaMKII Shuttles Ca2+/CaM to the Nucleus to Trigger CREB Phosphorylation and Gene Expression Huan Ma, Rachel D. Groth, Samuel M. Cohen, John F. Emery,

Figure S7

Cell 2014 159, 281-294DOI: (10.1016/j.cell.2014.09.019) Copyright © 2014 Elsevier Inc. Terms and Conditions

Page 16: ΓCaMKII Shuttles Ca2+/CaM to the Nucleus to Trigger CREB Phosphorylation and Gene Expression Huan Ma, Rachel D. Groth, Samuel M. Cohen, John F. Emery,

Cell 2014 159, 281-294DOI: (10.1016/j.cell.2014.09.019) Copyright © 2014 Elsevier Inc. Terms and Conditions