brittany lilos. a parasitic disease found in parts of the tropics, subtropics, and southern europe

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Brittany Lilos

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Brittany Lilos

A parasitic disease found in parts of the tropics, subtropics, and southern Europe

It is caused by Leishmania, a protozoan parasite.

It is caused by Leishmania, a protozoan parasite.

Zoonotic disease

By bites of female Phlebotomine Sandfly

By bites of female Phlebotomine Sandfly

Blood transfusions, contaminated needles

By bites of female Phlebotomine Sandfly

Blood transfusions, contaminated needles

Congential transmission (rare)

Contagious through physical contact?

Contagious through physical contact?

No!

Only through ways mentioned..

SMALL Noiseless Bites may not

hurt!

SMALL Noiseless Bites may not

hurt!

“Black fever”

Most dangerous form!

“Black fever”

Most dangerous form!

Nearly always fatal if left untreated

“Black fever”

Skin sores

Skin sores

Can spread to nose/mouth

and cause Mucocutaneous Leishmaniasis

produces disfiguring lesions which destroy the mucous membranes of the nose, mouth, and throat

a. Cutaneousb. Mucocutaneo

usc. Visceral

All ages

All ages

Depends on LOCATION

All ages

Depends on LOCATION

Highest risk time: dawn to dusk

Missionaries

TravelersSoldiers

Anyone who is active/does research at night

1. Looking for symptoms

2. Examining tissue samples for Leishmania parasite

3. Doing blood tests that detect antibody (immune response)

Pentostam

There is an effective set of FIRST LINE DRUGS used for treatment.

Glucantime

There is an effective set of FIRST LINE DRUGS used for treatment.

Lomidine

Fungizone

If those do not work, there are also SECOND LINE DRUGS.

Allopurinol

Ambisome

Ketaconazole

…Experimental Treatments

Vaccine?

Science News

Visceral Leishmaniasis: Successful Vaccine Trial In DogsScienceDaily (Aug. 16, 2005) — Visceral leishmaniasis, which is the most severe form of that group of diseases, affects 500 000 people in the world each year. …

Paromomycin Intramuscular (IM) Injection for visceral leishmaniasis

Paromomycin Intramuscular (IM) Injection for visceral leishmaniasis

1. Spray living, sleeping areas with insecticide

1. Spray living, sleeping areas with insecticide

2. If needed, use a bed net

Pictures:

http://news.bbc.co.uk/2/shared/spl/hi/health/03/travel_health/diseases/html/leishmaniasis.stm

http://www.susanamendez.com/LeishmaniaFacts/WhatIsLeishmaniasis.html

http://www.nlm.nih.gov/medlineplus/ency/imagepages/2652.htm

http://www.who.int/entity/leishmaniasis/disease_epidemiology/en/index.html 

http://commons.wikimedia.org/wiki/Image:Globe.svg

(map) http://www.wehi.edu.au/research/divisions/inf/labs/handman/leishmaniasis.html

http://www.keele.ac.uk/depts/aep/staff/rdcmres.htm

http://www.sciencedaily.com/releases/2008/08/080814154331.htm

http://www.fic.nih.gov/news/publications/global_health_matters/GHM_leishmaniasis_10-07.htm

http://www.stanford.edu/group/parasites/ParaSites2006/Leishmaniasis/LandR.htm 

http://en.wikipedia.org/wiki/Leishmaniasis 

http://www.nature.com/nrmicro/journal/v5/n11_supp/fig_tab/nrmicro1748_F2.html

(first chart) http://www.infektionsforschung.uni-wuerzburg.de/research/agmoll/research/ 

(bio chart) http://www.wehi.edu.au/research/overview/inf.html

http://edoc.hu-berlin.de/dissertationen/al-jawabreh-amer-2005-11-25/HTML/chapter1.html

http://freepages.genealogy.rootsweb.ancestry.com/~leveritt/2610.htm 

http://www.ccr.ust.hk/research%20area.htm

http://helpithinkimarockstar.blogspot.com/2008/08/on-road-warfare-gray-hair-and-rainy.html

http://www.state.gov/r/pa/ei/pix/b/nea/iraq/19134.htm

http://www.miyazaki-med.ac.jp/parasitology/orphan/HTML/med/4sodium.html 

http://www.speciation.net/Public/Objects/Glossary/?we_objectID=854 

http://en.wikipedia.org/wiki/Glucantime

http://www.sciencedaily.com/releases/2005/08/050814165616.htm

http://www.oneworldhealth.org/leishmaniasis

http://www.global-b2b-network.com/b2b/26/844/pest_control.html

http://www.jvibe.com/node/1672

http://www.outdoorlife.com/article/Survival/Survival-Tip-of-the-Day-1000063128 

http://teaching.path.cam.ac.uk/partIB_pract/P14/

http://www.bullwrinkle.com/ShoppingPages/allopurinol_dogs.htm

http://www.drug3k.com/drug/Ambisome-12207.htm