brachytherapy in carcinoma prostate

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prostate

Brachytherapy in carcinoma prostateDr SailendraSenior resident Dept of radiotherapyMaulana azad medical college

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rationaleprostate adenocarcinoma has a low /-ratio of 1.23.0 GyLate reacting tiisues are more sensitive to higher does per fractionIt is a form of conformal radiotherapy that avoids dose to normal structuresShorter duration of treatment

History of brachytherapy1910 - Young used urethral radium for treatment of prostate cancer1930 - Flocks first injected radioactive gold liquid into prostate 1970 -Whitmer et al. at MSKCC in New York first performed prostate seed implants using iodine seeds1983 - Holm performed the first closed implant,using needles and ultrasound guidance

INCLUSION CRITERIAPATIENT FACTORSLife expectancy >5 yearsIPSS 100 % of prescribed dose(PD) pV100 95 %,pV150 50 %RectumrD2cc PD and rD0.1cc

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