boost oral nutritional supplements helping adult …

1© 2021 Nestlé.

BOOST® ORAL NUTRITIONAL

SUPPLEMENTS

HELPING ADULT PATIENTS MEET THEIR NUTRITIONAL NEEDS

MALNUTRITION & DIABETES

2© 2021 Nestlé.

NESTLÉ HEALTH SCIENCE

Nestlé Health Science is a leader in the field of nutritional science, committed to

empowering healthier lives through nutrition and redefining the management of

health. We offer an extensive portfolio of science-based consumer health, medical

nutrition, and supplement brands.

I N T R O D U C T I O N

Did you know...?The use of ONS is recommended by both

the World Health Organization and the

European Society for Clinical Nutrition

and Metabolism.6,7

• Malnutrition affects up to 50% of hospitalized older adults.1 • Intervention with oral nutritional supplements (ONS), such as BOOST® drinks, along with regular food intake, has been shown to improve clinical and health economic outcomes:2-5

1. Kaiser MJ et al. J Am Geriatr Soc. 2010;58(9):1734-1738. 2. Snider JT et al. JPEN. 2014;38(2 suppl):77S-85S. 3. Barrett ML et al. 2016 US AHRQ August 30, 2018. Available at: https://www.hcup-us.ahrq.gov/reports.jsp 4. Philipson TJ et al. Am J Manag Care. 2013;19:121-28 5. Sriram K et al. JPEN. 2017;41:384-91. 6. WHO Guidelines on Integrated Care for Older People (ICOPE) 2017. 7. Volkert D et al. ESPEN Guideline on Clinical Nutrition and Hydration in Geriatrics. Clin Nutr. 2019;38:10-47.

26% reduction

in 30-day readmission

rates5

21.6% decrease in inpatient

episode cost4

21% reduction

in LOS4

3© 2021 Nestlé.

Initiate nutrition care for your (at-risk) malnourished patients with BOOST® Nutritional Drinks

*Clinically shown to produce a lower blood sugar response vs. a standard nutritional drink in people with type 2 diabetes. BOOST Glucose Control® Drinks are intended for use under medical supervision as part of a diabetes management platn. Not a substitute for medication. All trademarks are owned by Société des Produits Nestlé S.A., Vevey, Switzerland, or used with permission. © 2021 Nestlé.

Nestlé Health Science provides a comprehensive ONS portfolio to help meet a wide variety of nutritional needs, including for patients with malnutrition.

HIGH CALORIE/HIGH PROTEIN HIGH CALORIE HIGH PROTEIN HIGH PROTEIN/

DIABETES NUTRITION DIABETES NUTRITION CLEAR LIQUID NUTRITION EVERYDAY NUTRITION

BOOST® VERY HIGH CALORIE

BOOST PLUS® BOOST® HIGH PROTEIN

BOOST GLUCOSE CONTROL® MAX 30g PROTEIN*

BOOST GLUCOSE CONTROL®*

BOOST® SOOTHE

BOOST BREEZE®

BOOST® ORIGINAL

530 Calories 360 Calories 240 Calories 160 Calories 190 Calories 300 Calories 250 Calories 240 Calories

22g Protein 14g Protein 20g Protein 30g Protein 16g Protein 10g Protein 9g Protein 10g Protein

26 Vitamins & Minerals



25 Vitamins &Minerals





GLUTEN FREE ✓ ✓ ✓ ✓ ✓ ✓ ✓ ✓NO ARTIFICIAL COLORS ✓ ✓ ✓ ✓ ✓ ✓ ✓

NO ARTIFICIAL SWEETENERS ✓ ✓ ✓ ✓ ✓ ✓

A D D R E S S I N G M A L N U T R I T I O N W I T H O N S

4© 2021 Nestlé.

B O O S T P O R T F O L I O O V E R V I E W

High Protein BOOST® Nutritional Drinks help deliver the protein patients need

M A L N U T R I T I O N - F O C U S O N H I G H P R O T E I N

1. Bauer J et al. J Am Med Dir Assoc. 2013;14(8):542-559. 2. Deutz NE et al. Clin Nutr. 2014;33(6):929-936. 3. Weijzen M, et al. NCP. 2020;35(4):655-663.

HIGH PROTEIN/HIGH CALORIE

HIGH PROTEIN/MODERATE CALORIE

HIGH PROTEIN/FEWER CALORIES


BOOST® HIGH PROTEIN

BOOST GLUCOSE CONTROL® MAX 30g PROTEIN

22g PROTEIN 20g PROTEIN 30g PROTEIN

530 Calories 240 Calories 160 Calories

2.24 kcal/mL 1.0 kcal/mL 0.5 kcal/mL

Experts recommend higher protein intake (beyond the RDA) in older adults (>65 yrs) to maintain muscle and functionality1,2

PR

OTE

IN L

EVEL

S

Current RDA

0.8 g/kg

RDA (19–70+ yrs)

1.0–1.2 g/kg

New minimum for healthy

older adults

1.2–1.5 g/kg

Acute or chronic disease

Up to 2.0 g/kg

Severe illness or injury, or

marked malnutrition

Expert Recommendations >65 years

• Older adults often eat poorly consuming less than 50% of both protein and energy requirements from hospital meals3

• 96% of older hospitalized patients with [or at-risk of] malnutrition do not meet the recommended protein intake of ≥1.2g protein/kg/day3

High Protein BOOST® drinks contain 20-30g high-quality protein with a range of calories to help meet individual nutritional needs.

5© 2021 Nestlé.

MALNUTRITION & DIABETES

Learn about Clinical and Economic Impacts of Malnutrition

Learn about Acute and Long-Term Impacts of Hyperglycemia

View Sample Patient Profile

6© 2021 Nestlé.

D I A B E T E S & M A L N U T R I T I O N - P R E V A L E N C E

1 in 5

1 in 3

hospitalizations involves a patient with diabetes4

non-ICU patients in community hospitals experience hyperglycemia4

1. Sanz Paris A et al. Nutr Hosp 2013;28(3):592-599 2. CDC National Diabetes Statistics Report 2020 3. Ahmed N et al. BMJ Open Diabetes Res Care 4. Umpierrez GE et al. J Clin Endocrinol Metab 2012;97(1):16–38. 2018;6:e000471

A multicenter study found that 21% of older adults with diabetes had malnutrition at hospital admission, with another 39% at risk of malnutrition1

Did you know...?89% of people with diabetes in the US are overweight or obese, which may interfere with proper recognition and diagnosis of malnutrition.1-3

1 in 4 adults age 65 years and older have diabetes2

7© 2021 Nestlé.

Malnutrition is associated with worse clinical and health economic outcomes in patients with diabetes1-4

D I A B E T E S & M A L N U T R I T I O N - C L I N I C A L & H E A LT H E C O N O M I C I M P A C T

INCREASED

ComplicationsLength of StayHealthcare Costs MortalityHealthcare Utilization

DECREASED

Likelihood of Discharge HomeQuality of LifeMuscle FunctionWound HealingImmune Response

1.7x greater

annual healthcare costs1

58% increase

in LOS2

1. Ahmed N et al. BMJ Open Diabetes Res Care 2018;6:e000471 2. Sanz Paris A et al. Nutr Hosp 2013;28(3):592-599 3. Pamukg et al. Int J Diabetes Devel Countries. 2020 4. Sanz-Paris A et al. JPEN 2020;44(8): 1492-1500

24% reduction in discharge

home2

Learn more about how nutrition affects immune health

8© 2021 Nestlé.

Managing blood sugar is important for both acute and long-term outcomes

D I A B E T E S - I M P O R T A N C E O F B L O O D S U G A R M A N A G E M E N T

1. Fortmann AL et al. Diabetes 2015 Jun; 64(Supplement 1): A1-A100. Study of n=9.995 patients with diabetes admitted to hospitals in community health system in California

ACUTEPatients with abnormal blood sugar levels have longer, more costly hospital stays vs. those with glucose levels in a target range1

LONG TERMHyperglycemia increases risk for complications, including cardiovascular disease, and damage

to eyes, nerves, kidneys, and feet

MACROVASCULAR COMPLICATIONS

Transient ischaemic attackStroke

AnginaMyocardial infarction

Cardiac failure

Peripheral vascular damage

MICROVASCULAR COMPLICATIONS

Diabetic retinopathy• Non-proliferative• Proliferative• Macular oedema

MicroalbuminuriaMacroalbuminuriaEnd-stage renal disease

Erectile dysfunction

Autonomic neuropathy

Peripheral neuropathyOsteomyelitisAmputation

48% increase in LOS1

18% higher costs1

Significantly longer LOS(8.5 d vs. 5.74 days)

Significantly higher variable costs ($16,382 vs. $13,896)

Adapted from: Chawla D, Tripathi AK. Integr Food Nutr Metab. 2019;6:1-6.

9© 2021 Nestlé.

BOOST Glucose Control® Drink is clinically shown to produce a lower blood sugar response vs. a standard nutritional drink in people with type 2 diabetes1

D I A B E T E S - B O O S T G L U C O S E C O N T R O L ® D R I N K C A N H E L P M A N A G E B L O O D S U G A R L E V E L S

DECREASED

Peak Blood Glucose Concentrations by 20% (p<0.01)

Glucose Area Under the Curve (AUC0-240 min), p<0.01

1. Klosterbuer A et al. JPEN J Parenter Enteral Nutr. 2021;45:S194-195.

BOOST Glucose Control® Drink is intended for use under medical supervision as part of a diabetes management plan. Not a substitute for medication.

Mea

n B

lood

Glu

cose

(Cha

nge

from

bas

elin

e, m

g/dL

)

Postprandial Blood Glucose Response

Standard Nutritional Drink

Time (min)

0 60 120 180 240

BOOST Glucose Control® Drink

0

-30

-20

-10

10

20

30

40

50

60

70

10© 2021 Nestlé.

2 cartonsPER DAY provides

380 KCAL with

32gPROTEIN

PATIENT WITH TYPE 2 DIABETES HOSPITALIZED WITH PNEUMONIA

Dave, 76-year-old Male

Diagnosis: Type 2 diabetes, hypertension

Medications: Metformin, lisinopril, atorvastatin

Height: 5’10” / Weight: 91 kg / 200 lbs / BMI: 28.7

Clinical observations:

• Loss of muscle mass

• Reduced muscle function (low grip strength)

• Shortness of breath

Blood glucose measurements: HbA1c of 7%, Time-in-Range: 53%

Energy Needs: 25–30 kcal/kg BW (2200–2700 kcal/d)

Protein Needs: 1.2–1.5 g/kg BW (109–136g protein/d)

Diet history: Frequently skips breakfast, consumes 3–4 snacks per day

1. Yeo HJ et al. Korean J Intern Med. 2019 Jul; 34(4):841–849. 2. Kornum JB et al. Diabetes Care 2007; 0(9):2251-2257. 3. Deutz NE et al. Clin Nutr 2016;35(1):18-26. 4. Klosterbuer A et al. JPEN J Parenter Enteral Nutr. 2021;45:S194-195.*Not a substitute for medication

Provision of ONS to malnourished older adults during and after hospitalization for pneumonia, CHF, acute myocardial infarction, or COPD improved nutrition status, body weight, and 90-d mortality3

BOOST Glucose Control® Balanced Nutritional Drink is clinically shown to produce a lower blood sugar response vs. a standard nutritional drink in people with type 2 diabetes*4

BOOST GLUCOSE CONTROL® DRINK DESIGNED FOR YOUR PATIENTS WITH DIABETES.

O L D E R M A L N O U R I S H E D P A T I E N T W I T H D I A B E T E S –

S A M P L E P A T I E N T P R O F I L E

Did you know...?Malnutrition has been reported in up to 50% of patients hospitalized with community acquired pneumonia.1

Patients with type 2 diabetes are at increased risk for pneumonia, and higher blood sugar levels are associated with poorer outcomes.2

11© 2021 Nestlé.

2 bottlesPER DAY provides

320 KCAL with

60gPROTEIN

PATIENT WITH TYPE 2 DIABETES HOSPITALIZED WITH FOOT ULCER INFECTION

Juan, 66-year-old Male

Diagnosis: Type 2 diabetes, peripheral artery disease

Medications: Glipizide, Metformin, Cilostazol

Height: 5’8” / Weight: 93 kg / 205 lbs / BMI: 31.2

Clinical observations:

• Low muscle mass

• Reduced grip strength

• Obesity

• Grade 1 foot ulcer

• Normal appetite

Energy Needs: 25–30 kcal/kg BW (2300–2800 kcal/d)

Protein Needs: 1.2–1.5 g/kg BW (112–140g protein/d)

BOOST GLUCOSE CONTROL® MAX 30g PROTEIN DRINK DESIGNED FOR YOUR PATIENTS WITH DIABETES.

O L D E R M A L N O U R I S H E D P A T I E N T W I T H D I A B E T E S –

S A M P L E P A T I E N T P R O F I L E

Provision of diabetes-specific ONS along with nutrition education has been shown to improve nutritional intake and wound healing in patients with DFU3

BOOST Glucose Control® MAX 30g Protein Drink provides 30g high- quality protein, and is clinically shown to produce a lower blood sugar response vs. a standard nutritional drink in people with type 2 diabetes*4

Did you know...?At least 15-25% of individuals with diabetes will develop a diabetic food ulcer (DFU) over their lifetime.1 More than half of DFU become infected, which significantly increases the risk of hospital admission.1 Patients with DFU are at high risk of malnutrition and often have inadequate intake of protein and micronutrients.2

1. Skrepnek GH et al. Diabetes Care. 2017;40:936-942. 2. Maier HM et al. J Nutr Ther. 2016;5:85–92. 3. Basiri R et al. Biomedicines. 2020;8:263 4. Klosterbuer A et al. JPEN. 2019;43(3):445-445.*Not a substitute for medication

12© 2021 Nestlé.

BOOST® PORTFOLIO ORAL NUTRITIONAL SUPPLEMENTS

View BOOST® Portfolio by Segment

BOOST® Be WellTM Program

Nutrition and Immune Health

13© 2021 Nestlé.

High Calorie High Protein Diabetes Nutrition

B O O S T ® O N S P O R T F O L I O

Nestlé Health Science provides a comprehensive portfolio of BOOST® ONS to meet a wide variety of needsWhether your patient needs more calories, extra protein, nutrition suitable for people with diabetes, clear liquid nutrition or general supplemental nutrition, there’s a BOOST® nutritional product to help meet their needs.

Clear Liquid General Supplemental Nutrition

14© 2021 Nestlé.


Nestlé Health Science BOOST® ONS Portfolio: High Calorie

High Calorie NUTRITIONAL APPLICATIONS BOOST® VERY HIGH CALORIE

BOOST PLUS®

Increased energy needs ✓ ✓

Weight gain or maintenance ✓ ✓

Fluid restriction ✓ ✓

Volume intolerance ✓ ✓

Malnutrition ✓ ✓

SUITABLE FOR THESE DIETS

Lactose Intolerance (not for individuals with galactosemia) ✓ ✓

Gluten free ✓ ✓

Kosher ✓ ✓


BOOST PLUS®

(INSTITUTIONAL & RETAIL)

Volume 237 mL 237 mL

Caloric Density2.24

kcal/mL1.5

kcal/mL

Calories 530 360

Protein (g) 22 14

Carbs (g) 52 45

Sugars (g) 13 24

Fat (g) 26 14

15© 2021 Nestlé.

Nestlé Health Science BOOST® ONS Portfolio: High Protein


High Protein





Volume 237 mL 237 mL 325 mL

Caloric Density

2.24 kcal/mL

1.0 kcal/mL

0.5 kcal/mL

Calories 530 240 160

Protein (g) 22 20 30

Carbs (g) 52 28 4-6

Sugars (g) 13 15 1

Fat (g) 26 6 2-3

NUTRITIONAL APPLICATIONS BOOST® VERY HIGH CALORIE




General oral supplement needs ✓ ✓ ✓

General protein needs ✓ ✓ ✓

Increased protein requirements ✓ ✓ ✓

Reduced appetite ✓ ✓ ✓




Gluten free ✓ ✓ ✓

Kosher ✓ ✓ ✓

Low fat ✓

Carbohydrate restricted ✓

16© 2021 Nestlé.

Nestlé Health Science BOOST® ONS Portfolio: Diabetes Nutrition


1. Klosterbuer A et al. JPEN J Parenter Enteral Nutr. 2021;45:S194-195. 2. Klosterbuer A et al. JPEN. 2019;43(3):445-445.

Diabetes Nutrition

BOOST® GLUCOSE CONTROL® (INSTITUTIONAL & RETAIL)



Caloric Density0.8

kcal/mL0.5

kcal/mL

Calories 190 160

Protein (g) 16 30

Carbs (g) 16 4-5

Sugars (g) 4 1

Fat (g) 7 2-3

NUTRITIONAL APPLICATIONSBOOST

GLUCOSE CONTROL® (INSTITUTIONAL & RETAIL)


General oral supplement needs ✓ ✓

General protein needs ✓ ✓

Increased protein requirements ✓ ✓

Malnutrition ✓


Lactose Intolerance (not for individuals with galactosemia) ✓

Gluten free ✓ ✓

Kosher ✓ ✓

Halal ✓

Low Fat ✓

Carbohydrate restricted ✓ ✓BOOST Glucose Control® Drinks are clinically shown to produce a lower blood sugar response vs. a standard nutritional drink in people with type 2 diabetes*1,2

*Not a substitute for medication

17© 2021 Nestlé.

Nestlé Health Science BOOST® ONS Portfolio: Clear Liquid


Clear Liquid

BOOST BREEZE®

BOOST® SOOTHE


Caloric Density1.06

kcal/mL1.3

kcal/mL

Calories 250 300

Protein (g) 9 10

Carbs (g) 54 65

Sugars (g) 34 15

Fat (g) 0 0

# Vitamin & Minerals (≥ 10% Daily Value)

19 0

NUTRITIONAL APPLICATIONS BOOST BREEZE®

BOOST® SOOTHE

Clear liquid diet ✓ ✓

Fat malabsorption ✓ ✓


Nutrition support for patients experiencing certain side effects of cancer treatment, such as taste alterations and oral discomfort

✓



Gluten free ✓ ✓

Kosher ✓ ✓

Halal ✓

18© 2021 Nestlé.

Nestlé Health Science BOOST® ONS Portfolio: General Supplemental Nutrition


General Supplemental Nutrition

BOOST® ORIGINAL DRINK


BOOST® NUTRITIONAL

PUDDING

Volume 237 mL 5 oz

Caloric Density1.0

kcal/mL1.6

kcal/mL

Calories 240 230

Protein (g) 10 7

Carbs (g) 41 32

Sugars (g) 20 14

Fat (g) 4 8

NUTRITIONAL APPLICATIONS BOOST® ORIGINAL

BOOST® PUDDING

Inadequate oral intake ✓ ✓

General oral supplements needs ✓ ✓

Reduced appetite ✓ ✓


Fluid restriction ✓



Gluten free ✓ ✓

Kosher ✓ ✓

19© 2021 Nestlé. 1. McAuliffe S et al. BMJ Nutrition Prevention Health. 2020;0 2. Wu D et al. Front Immunol. 2019;9(3):3160. 3. Bauer J et al. JAMDA 2013;14(8):542-59. 4. Maggini S et al. Nutrients. 2018;10:1531. 5. Reider CA. Nutrients 2020;12,1735 6. Krok-Schoen et al. J Nutr Health Aging. 2019;23(4):338-347 7. USDA, ARS. 2020. What We Eat in America, NHANES 2017-2018.

M A L N U T R I T I O N , I M M U N E H E A LT H A N D N U T R I T I O N

Nutrition + Immune HealthMalnutrition contributes to poor health and disease outcomes, weakening the body’s immune system and thereby increasing susceptibility to infection and illness. Proper nutrition, including protein, vitamins and minerals, is essential to support the normal functioning of the immune system.1,2

AGINGis associated with a decline in the body’s

immune response, which can increase the risk of infection and severity

of disease.3,4

NUTRIENT INADEQUACIES

are found in the diets of many older adults. Almost half fall short

of meeting nutritional requirements for protein, and many don’t get enough vitamins and minerals.

Nutrient inadequacies can impair immune function and weaken the

immune system.2,4-7

BOOST® DRINKSprovide high-quality protein, vitamins C & D, zinc, iron and selenium, key nutrients for

immune support and normal immune function.

20© 2021 Nestlé.

N U T R I T I O N S U P P O R T

BOOST® Be Well™ Program

Designed for patients after hospitalization, BOOST® Be Well™ is a subscription, nutrition support and education program that delivers BOOST® Nutritional Drinks straight to your patient’s door during their recovery.

To learn more, visit: www.BOOSTBeWell.com/start

HOW IT WORKS

1 2 3Patient/Caregiver createsan account and answers afew questions about their

recovery journey.

A tailored nutritional offering is suggested based

on the patient’s needs.

Patient/Caregiver selectsBOOST® purchases of choiceand confirms free delivery

preferences.

http://www.BOOSTBeWell.com/start

21© 2021 Nestlé.© 2021 Nestlé.

FOR ADDITIONAL TOOLS & RESOURCES

For more information, visit: NestleMedicalHub.com NestleMedicalHub.com/MalnutritionNestleMedicalHub.com/DiabetesNestleMedicalHub.com/Oncology

For samples, visit:NestleMedicalHub.com/Samples

Download the NHSc Product Guide & Nestlé Medical Hub app today!

All trademarks are owned by Société des Produits Nestlé S.A., Vevey, Switzerland, or used with permission. © 2021 Nestlé.

http://www.nestlemedicalhub.com

http://www.nestlemedicalhub.com/therapeutic-areas/malnutrition

http://www.nestlemedicalhub.com/therapeutic-areas/diabetes

http://www.nestlemedicalhub.com/therapeutic-areas/oncology

http://www.nestlemedicalhub.com

boost oral nutritional supplements helping adult …

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