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  • Slide 1
  • Biostatistics-Lecture 14 Generalized Additive Models Ruibin Xi Peking University School of Mathematical Sciences
  • Slide 2
  • Generalized Additive models Gillibrand et al. (2007) studied the bioluminescence-depth relationship
  • Slide 3
  • Generalized Additive models Gillibrand et al. (2007) studied the bioluminescence-depth relationship We may first consider the model
  • Slide 4
  • Generalized Additive models Gillibrand et al. (2007) studied the bioluminescence-depth relationship We may first consider the model
  • Slide 5
  • Generalized Additive models Gillibrand et al. (2007) studied the bioluminescence-depth relationship We may first consider the model
  • Slide 6
  • Generalized Additive models LOESS (locally weighted scatterplot smoothing)-based
  • Slide 7
  • Generalized Additive models LOESS (locally weighted scatterplot smoothing)-based
  • Slide 8
  • Generalized Additive models LOESS (locally weighted scatterplot smoothing)-based
  • Slide 9
  • Generalized Additive models LOESS (locally weighted scatterplot smoothing)-based
  • Slide 10
  • Generalized Additive models LOESS (locally weighted scatterplot smoothing)-based Spline-based
  • Slide 11
  • Generalized Additive models LOESS (locally weighted scatterplot smoothing)-based Spline-based
  • Slide 12
  • Generalized Additive models Suppose that the model is As discussed before, we may approximate the unknown function f with polynomials But the problem is this representation is not very flexible
  • Slide 13
  • Generalized Additive models
  • Slide 14
  • What if the data looks like
  • Slide 15
  • Generalized Additive models One way to overcome this difficulty is to divide the range of the x variable to a few segment and perform regression on each of the segments
  • Slide 16
  • Generalized Additive models One way to overcome this difficulty is to divide the range of the x variable to a few segment and perform regression on each of the segments
  • Slide 17
  • Generalized Additive models One way to overcome this difficulty is to divide the range of the x variable to a few segment and perform regression on each of the segments The cubic spline ensures the line looks smooth
  • Slide 18
  • Generalized Additive models Cubic spline bases (assuming 0