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BIOMEDICAL ENGINEERING STUDY GUIDE 2018/2019 (version 3rd Sept 2018) – p1/39

BIOMEDICAL ENGINEERING MSc PROGRAM

STUDY GUIDE

2018-2019

https://brightspace.tudelft.nl


Disclaimer This study guide has been compiled with the utmost care and is based on information provided by the faculties involved; this information was up to date on September 3rd, 2018. Changes, additional information and detailed descriptions of subjects can be found on Brightspace: https://brightspace.tudelft.nl and/or in the digital study guide http://studiegids.tudelft.nl.


Table of Contents 1 INTRODUCTION 62 GOALS 73 QUALIFICATIONS OF BME MSC-GRADUATES 84 STUDY PROGRAM 9

4.1 GENERAL INFORMATION 94.1.1 Academic calendar and daily schedule 94.1.2 Lecture hours 114.1.3 Examinations 114.1.4 Study load and European Credits 11

4.2 OVERVIEW 124.3 FIRST YEAR 12

4.3.1 Individual Study Program (ISP) 134.4 SECOND YEAR 13

4.4.1 Internship in a hospital, industry or other research institute (15 EC) 134.4.2 Literature survey (10 EC) 134.4.3 Master thesis project (32 EC) 134.4.4 Literature and Introduction colloquium (2 EC) 144.4.5 Student colloquia (1 EC) 14

4.5 STUDENT INTERVIEWS 145 BME MSC PROGRAM TRACKS 15

5.1 TRACK I: MUSCULOSKELETAL BIOMECHANICS (MB) 165.2 TRACK II: MEDICAL DEVICES AND BIOELECTRONICS (MDB) 175.3 TRACK III: MEDICAL PHYSICS (MP) 185.4 ANNOTATION ENTREPRENEURSHIP 195.5 HONOURS PROGRAM 19

6 ADMISSION 206.1 ADMISSION FOR STUDENTS WITH AN ACADEMIC BACHELOR DEGREE 206.2 ADMISSION FOR STUDENTS WITH A BACHELOR DEGREE FROM A DUTCH SCHOOL FOR HIGHER VOCATIONAL EDUCATION (HBO) 21

6.2.1 Introduction 216.2.2 Pre-master program for students with an HBO degree in Mechanical Engineering, Aerospace Engineering or Human Kinetic Technology (Bewegingstechnologie) 216.2.3 Pre-master program for the students with an HBO in Applied Physics 226.2.4 Pre-master program for students with an HBO degree in Electrical Engineering 22

6.3 ADMISSION FOR STUDENTS STILL IN THEIR ACADEMIC BACHELOR PROGRAM 237 TEACHING IN LEIDEN (LUMC) AND ROTTERDAM (ERASMUS MC) 24

7.1 COURSES IN LEIDEN 247.2 COURSES IN ROTTERDAM 24

8 BME MASTER COURSES 258.1 OBLIGATORY COURSES ALL TRACKS 258.2 TRACK SPECIFIC OBLIGATORY COURSES 25

8.2.1 Courses Musculoskeletal Biomechanics track 268.2.2 Courses Medical Devices and Bioelectronics track 278.2.3 Courses Medical Physics track 28

8.3 FREE ELECTIVE COURSES 299 STUDY AND TRAINEESHIP ABROAD 3110 ENROLLING FOR COURSES AND TESTS 32


10.1 COURSES 3210.2 TESTS 32

11 ORGANIZATION 3311.1 FACULTY OF 3ME 3311.2 ORGANIZATIONAL STRUCTURE 3311.3 EDUCATION SUPPORT STAFF 3311.4 BOARD OF STUDIES 3411.5 BOARD OF EXAMINERS 3511.6 STUDENT ASSOCIATION 3511.7 MSC COORDINATOR 3511.8 ACADEMIC COUNSELLOR 35

11.8.1 Individual help and advice 3611.8.2 Personal circumstances 3611.8.3 Alerting the Examination Committee, professors, and other members of staff 36

11.9 FOREIGN STUDENT FINANCIAL SUPPORT (FSFS) 3612 FURTHER INFORMATION 37APPENDIX A 38APPENDIX B - ISP FORM 39


Preface We are glad that the MSc program in Biomedical Engineering (BME) will start again on Monday, September 3rd, 2018. Since the launch of the master program in 2004 many students were awarded their MSc-degree and most of them found that the program was exactly what they were looking for: challenging, exciting, relevant, multi-disciplinary, application-oriented and more. Almost all of them have been able to find rewarding jobs in the biomedical industry or in related fields, mostly as researchers or designers. The BME master program at Delft University of Technology (TU Delft) is an interfaculty program administrated by the Faculty of Mechanical, Maritime, and Materials Engineering (3mE) and supported by the Faculty of Applied Sciences and the Faculty of Electrical Engineering, Mathematics and Computer Science. Since the start of the program, existing research collaborations with Erasmus Medical Centre (Erasmus MC) and Leiden University Medical Centre (LUMC) have been integrated into the BME program through guest lectures, internships and graduation projects. In the last five years, these activities were significantly strengthened under the Medical Delta network (launched in 2008), which organizes invited lectures, internships, joint graduation projects, the development of new courses, as well as finding new partners, such as hospitals and companies in the region. In addition to Medical Delta, the participating groups and faculty members collaborate closely with other medical centers in the Netherlands, including the Academic Medical Center (AMC) of the University of Amsterdam, the University Medical Center of Utrecht (UMCU) and Maastricht University Medical Center (MUMC). Numerous biomedical companies at national and international levels also collaborate with faculty members in BME-related research projects and in graduation research projects by master students, many of which are directly or indirectly continued in PhD project. Furthermore, there is extensive collaboration with European and international universities in different projects. Indeed, many of our students opt to perform their internships, literature reviews and graduation projects abroad at host universities, often spending an extended period of time away (e.g. 3–9 months). While most of these graduation projects are organized at the inter-collegiate level, there is a formal relationship with fellow technical universities. TU Delft is a member of the European alliance called the IDEA League (ETH Zurich, RWTH Aachen, Chalmers University of Technology, Politecnico di Milano, TU Delft). This organization facilitates student exchange regarding regulations and financial support. Starting with the study year 2018-2019, the master BME program changed from a structure based on six specializations to a more general structure composed of three tracks. The BME program at the Delft University of Technology differs from other BME programs offered in the Netherlands because it focuses on producing good engineers in the traditional engineering disciplines who can apply their skills within multi-disciplinary research teams which also include medical scientists. The MSc program puts the emphasis on multi-disciplinary collaboration, and the MSc theses are often under the guidance of both technical and clinical tutors. In the field of biomedical engineering, there are still many new discoveries to be made, and there is a constant search for better equipment. It is a hi-tech field where research programs in universities can still compete (and collaborate) with industrial programs. Its importance for society as a whole is undeniable. It is very rewarding for students to see that their efforts can have an impact on clinical practice. We are looking forward to the coming year and the many new opportunities for students, researchers, and clinicians! Prof.dr. Amir A. Zadpoor, Director of Studies Iulian Apachitei, Master Coordinator


1 Introduction The BME Master program at the TU Delft is based on a long history of teaching and research in biomedical engineering within the three collaborating faculties: • Faculty of Mechanical, Maritime, and Materials Engineering (3mE), Department of Biomechanical

Engineering • Faculty of Applied Sciences (AS), Departments of Imaging Physics and of Radiation Science &

Technology • Faculty of Electrical Engineering, Mathematics and Computer Science (EEMCS), Department of

Microelectronics The Faculty of 3mE (Department of Biomechanical Engineering) coordinates the program. In combining the education and research programs of these three faculties, a broad BME program could be realized. Additionally, the program includes close and intensive collaboration with clinical partners at Leiden University Medical Centre (LUMC), the Erasmus Medical Centre Rotterdam (Erasmus MC), the Academic Medical Centre Amsterdam (AMC), the Free University Medical Centre (VUMC), the University Medical Center of Utrecht (UMCU) and Maastricht University Medical Center (MUMC). Clinical partners participate in first-year MSc teaching, and in the tutoring of MSc projects in the second year. Biomedical engineers have a solid technical background and additional knowledge of the medical field. In the biomedical industry, they apply their knowledge to the development and improvement of instruments for minimally invasive surgery, biomaterials, joint replacement prostheses, orthotics, pacemakers, catheters, etc. Within the health service, in particular in academic medical centers, biomedical engineers participate in research and education. Two examples are biomechanical research focused on the improvement of joint replacement prostheses at an orthopaedic department, and image processing research for the automated detection of narrowing blood vessels at a department of cardiology. As of 2018-2019, the MSc BME program consists of three tracks. One track requires a background in Mechanical Engineering (Musculoskeletal Biomechanics), one needs a background in Mechanical Engineering or Electrical Engineering (Medical Devices & Bioelectronics) and one requires a background in (Applied) Physics (Medical Physics). This means that BSc graduates in Mechanical Engineering, Applied Physics or Electrical Engineering from a University of Technology may enter the BME program without any restrictions. Academic BSc graduates holding other degrees may also enter the program but may need to acquire the required prerequisite knowledge. Graduates holding a degree from a Dutch polytechnic school (Technische Hogeschool) may also enter the program upon completion of some additional courses (the Pre-Master program). Please see Chapter 6 for detailed information on enrolment. Chapter 2 sets out the goals of the master program in Biomedical Engineering and Chapter 3 describes the qualifications of the MSc in Biomedical Engineering graduate. In Chapter 4, an overview of the study program is given. The three tracks are presented in more detail in Chapter 5. In Chapter 6, the admission programs for academic bachelors and Dutch polytechnic bachelor graduates are described. The medical courses on offer at LUMC and the Erasmus MC and in some of the research groups in the two academic hospitals that offer final master thesis assignments are presented in Chapter 7. Chapter 8 contains an overview of obligatory and elective courses per track. Chapters 9-12 provide further practical information.


2 Goals Biomedical Engineering problems usually require knowledge and expertise in all of the following areas:

• General knowledge of anatomy, physiology, biology and pathology • Fundamental knowledge in specific areas of engineering and/or physical sciences • Specialist knowledge in how biology/medicine principles are combined with

engineering/physical science to tackle specific problems within Biomedical Engineering • Scientific methodology and medical ethics

As academically trained professionals, biomedical engineers should understand and deploy soundly designed experiments, use proper statistics and implement good practice in data acquisition, archiving and interpretation as well as patient safety. They also need to possess at least a basic understanding of the main principles of evidence-based medicine, to be able to collaborate with clinicians, researchers or other health care professionals. The combination of all of the above-mentioned qualities enables biomedical engineers to impact healthcare quality through development and clinical translation of novel medical technologies. The BME program at the TU Delft focuses on three interconnected didactic goals: • To give students a fundamental understanding of the Biomedical Engineering discipline • To train students in the entire process of innovative thinking, design, manufacturing and assessment

of biomedical devices • To coach students to perform research in Biomedical Engineering at an academic level


3 Qualifications of BME MSc-graduates

The graduated Master of Biomedical Engineering meets, to a sufficient level, the following qualifications: 1. Competent in the scientific discipline Biomedical Engineering A graduate in Biomedical Engineering is able to: 1A. Apply a broad and profound knowledge of engineering sciences (mathematics and applied physics) to biomedical problems. 1B. Apply general and more advanced but specialized knowledge of anatomy and physiology to general and selected biomedical problems. 1C. Apply the knowledge of engineering sciences at an advanced level in at least one Biomedical Engineering specialization. 1D. Design, perform and evaluate experiments. 1E. Reflect on standard methods and their presuppositions and to questions these, propose adjustments, and to estimate their implications. 1F. Independently spot gaps in own knowledge and to independently revise and extend it through study. 2. Competent in doing research A graduate in Biomedical Engineering is able to: 2A. Independently generate new scientific knowledge and new insights within the field of Biomedical Engineering. 2B. Assess research, including scientific literature, within Biomedical Engineering on its scientific value. 2C. Individually produce and execute a research plan and to choose the appropriate level of abstraction. 2D. Deal with the changeability of the research process. 2E. Draw upon other disciplines, especially those from the medical field, in own research. 3. Competent in designing A graduate in Biomedical Engineering is able to: 3A. Systematically design complex biomedical systems. 3B. Generate innovative contributions to the discipline of Biomedical Engineering. 3C. Independently produce and execute a design plan, and to choose the appropriate level of abstraction. 3D. Deal with the changeability of the design process. 3E. Draw upon other disciplines, especially those from the medical field, in own design. 3F. Formulate new research questions on the basis of a design problem. 4. A scientific approach A graduate in Biomedical Engineering is able to: 4A. Identify and take in developments in the Biomedical Engineering domain. 4B. Critically examine existing theories, models, or interpretations within Biomedical Engineering. 4C. Analyse problems and use modelling, simulation, design and integration towards solutions. 4D. Document adequately the results of research and design, and to publish these results to contribute to the development of knowledge in

the Biomedical Engineering field and beyond. 4E. Reason logically within the field of Biomedical Engineering and beyond, to recognize modes of reasoning, and to recognize fallacies. 5. Basic intellectual skills A graduate in Biomedical Engineering is able to: 5A. Analyse and solve technological problems in a systematic way. 5B. Identify and acquire lacking expertise. 5C. Critically reflect on own knowledge, skills and attitude. 5D. Plan and execute research in changing circumstances. 5E. Integrate new knowledge in an R&D project, considering ambiguity, incompleteness and limitations. 5F. Remain professionally competent. 5G. Take a standpoint with regard to a scientific argument within the research area. 6. Competent in cooperating and communicating A graduate in Biomedical Engineering is able to: 6A. Work both independently and in multidisciplinary teams. 6B. Explain and defend outcomes from the research area to academia and industry, to specialists and a lay audience. 6C. Present and report in good English. 7. Considering the temporal and social context A graduate in Biomedical Engineering is able to: 7A. Apply a broad knowledge of medical ethics and medical statistics in own work. 7B. Understand and potentially implement the regulatory procedures required for certification of medical devices relevant to one biomedical

engineering specialization. 7C. Evaluate and assess the technological, ethical and societal impact of own work. 7D. Act responsibly with regard to sustainability, economy and social welfare. 7E. Interact effectively within clinical and pre-clinical settings with clinicians and medical researchers.


4 Study program As mentioned earlier, starting in 2018-2019 the BME Master program will be based on the new organizational structure in which the six original specializations have been clustered into three tracks, as follows: • Track I: Musculoskeletal Biomechanics • Track II: Medical Devices & Bioelectronics • Track III: Medical Physics At the beginning of the study program students must choose their track. Switching between tracks is possible, but students should consider the obligatory courses and additional courses required for each track. This chapter gives general information on teaching periods, examinations and European Credits, followed by a presentation of the first- and second-year study programs.

4.1 General information 4.1.1 Academic calendar and daily schedule The academic year is divided into two semesters. The semesters run from September to February and from February to September. Each semester consists of two periods. Each period consists of seven or eight weeks of teaching (the “teaching period”), followed by examination periods of varying lengths. There is an extra examination period in August, which is for retaking exams only. Vacations are around the Christmas and Easter periods and in the summer (see TU calendar for details - page 10). A course of lectures may, for example, have a 2/2/0/0 timetable. This means that there are two lecture hours scheduled for the subject in the first and second teaching periods and no lecture hours in the third and fourth periods. This means a total of 28-32 hours of lectures. All details on teaching and examination activities are presented in a timetable. These timetables are available on the TU Delft website https://www.tudelft.nl/en/student/education/timetables/ and on Brightspace, the virtual learning environment for students, lecturers and staff. You can find general timetable information on the Timetable page of the student portal.


TU Delft Calendar, Academic Year 2018/2019 1ND SEMESTER Week no. 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 1 2 3 4 5

Week type C C C C CT C C CW CWT T C C C C CT C V V C CW CW

T T

Teaching week 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 1.9 1.10 2.1 2.2 2.3 2.4 2.5 2.6 Christ-

mas Christ-mas 2.7 2.8 2.9 2.10

Monday Open.Acad.

year

10 17 24 1 8 15 22 29 5 12 19 26 3 10 17 24 31 7 14 21 28

Tuesday 4 11 18 25 2 9 16 23 30 6 13 20 27 4 11 18 25 1 8 15 22 29

Wednesday 5 12 19 26 3 10 17 24 31 7 14 21 28 5 12 19 26 2 9 16 23 30

Thursday 6 13 20 27 4 11 18 25 1 8 15 22 29 6 13 20 27 3 10 17 24 31

Friday 7 14 21 28 5 12 19 26 2 9 16 23 30 7 14 21 28 4 11 18 25 1

Saturday 8 15 22 29 6 13 20 27 3 10 17 24 1 8 15 22 29 5 12 19 26 2

Sunday 9 16 23 30 7 14 21 28 4 11 18 25 2 9 16 23 30 6 13 20 27 3

Sept. Oct. Nov. Dec. Jan. 2ND SEMESTER Week no. 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 Week type V C C C C CT C C CW CW

T T C C C C C CT C C CW CW

T T

Teaching week

Spring 3.1 3.2 3.3 3.4 3.5 3.6 3.7 3.8 3.9 3.10 4.1 4.2 4.3 4.4 4.5 4.6 4.7 4.8 4.9 4.10 4.11

Monday 4 11 18 25 4 11 18 25 1 8 15 Easter 29 6 13 20 27 3 Whit

monday

17 24 1

Tuesday 5 12 19 26 5 12 19 26 2 9 16 23 30 7 14 21 28 4 11 18 25 2

Wednesday 6 13 20 27 6 13 20 27 3 10 17 24 1 8 15 22 29 5 12 19 26 3

Thursday 7 14 21 28 7 14 21 28 4 11 18 25 2 9 16 23 Ascen

sion day

6 13 20 27 4

Friday 8 15 22 1 8 15 22 29 5 12 Good

fri-day

26 3 10 17 24 31 7 14 21 28 5

Saturday 9 16 23 2 9 16 23 30 6 13 20 27 4 11 18 25 1 8 15 22 29 6

Sunday 10 17 24 3 10 17 24 31 7 14 21 28 5 12 19 26 2 9 16 23 30 7

Feb. March April May June July SUMMER PERIOD 2019

Week no. 28 29 30 31 32 33 34 35

Week type V V V V V H V V

Teaching week 5.1 5.2 5.3 5.4 5.5 5.6 5.7 5.8

Monday 8 15 22 29 5 12 19 26

Tuesday 9 16 23 30 6 13 20 27

Wednesday 10 17 24 31 7 14 21 28

Thursday 11 18 25 1 8 15 22 29

Friday 12 19 26 2 9 16 23 30

Saturday 13 20 27 3 10 17 24 31

Sunday 14 21 28 4 11 18 25 1

C = Lectures and other teaching activities

CT = Lectures and examinations BSc-programmes

CW = Lectures / free week; varies per study programme

CWT = Lectures / free week / examinations; varies per study programme

T = Examinations / resits

H = Resits

V =

No teaching; vacation or public holiday

2 September – Start Academic year 2019/2020


4.1.2 Lecture hours

Day period Time 1 08.45 – 09.30 2 09.45 – 10.30 3 10.45 – 11.30 4 11.45 – 12.30

Break 12.30 - 13.30 5 13.45 – 14.30 6 14.45 – 15.30 7 15.45 – 16.30 8 16.45 – 17.30 9 17.45 – 18.30 10 18.45 – 19.30

4.1.3 Examinations Examinations may be oral or written. For those subjects in which written exams are scheduled, students will have at least one opportunity per year to re-sit examinations (written or oral). Exams are scheduled immediately after the period in which the course is taught. Re-sits generally take place after the next period. Re-sits for examinations taken in period 4 (Q4) are planned in the second half of August. 4.1.4 Study load and European Credits The study load of a course is expressed in European Credits (EC) to reflect the European Credit Transfer System (ECTS), which encourages acknowledgment of qualifications between higher education institutions in the European Union. The study load for one study year is 60 EC. Credits give an indication of the relative weights of certain parts of the course. One EC involves approximately 28 study hours. The study load includes all time spent on the course: lectures, private study, traineeship, practical assignments, examinations, etc. The study program involves two years of study, each with a study load of 60 EC. The total BME program is worth 120 EC.


4.2 Overview An overview of the BME program is provided in Table 4.1.

Table 4.1. Overview of BME Master program

First year Courses 60 EC

Track I Musculoskeletal Biomechanics

Track II Medical Devices & Bioelectronics

Track III Medical Physics

Obligatory courses all tracks (14 EC)

1. Experimental Design, Statistics & the Human (2 EC) 2. Anatomy & Physiology (only for students with technical background) (4 EC) 3. Medical Technology I (Diagnostic Devices) & Healthcare Systems (5 EC) 4. Ethics of Healthcare Technologies (3 EC)

First list of track-specific obligatory courses (24-25 EC)

1. Neuromechanics & Motor Control (5 EC) 2. Computational Mechanics of Tissues & Cells (6 EC) 3. Tissue Biomechanics of Bone, Cartilage & Tendon (3 EC) 4. System Identification & Parameter Estimation (7 EC) 5. Biomechatronics (4 EC)

1. Biomaterials (4 EC) 2. Applied Experimental Methods (4 EC) 3. Medical Inst A: Clinical Challenges & Eng Sol (3 EC) 4. 3D Printing (4 EC) 5. Active Implantable Biomedical Microsystems (5 EC) 6. Themes in Biomedical Electronics (4 EC)

1. Advanced Digital Image Processing (6 EC) 2. Medical Imaging & Systems (6 EC) 3. Radiological Health Physics (6 EC) 4. Medical Phys of Phot & Proton Ther (6 EC)

Second list of track-pre-selected electives (a choice of 3 for Tracks I&II and 2 for Track III) 1. Biomaterials (4 EC) 2. 3D Printing (4 EC) 3. Special Topics in Sports Engineering (3 EC) 4. Multibody Dynamics B (4 EC) 5. The Human Controller (3 EC) 6. Biomedical Engineering Design (4 EC) 7. Man-machine Systems (4 EC) 8. Control System Design (3/6 EC)

1. Regenerative Medicine (4 EC) 2. Computational Mechanics of Tissues & Cells (6 ECT) 3. Medical Inst B: Quality Assurance in Design (3 EC) 4. Tissue Biomech of Bone, Cartilage & Tendon (3 EC) 5. System Identification & Parameter Estimation (7 EC) 6. Biomedical Engineering Design (4 EC) 7. System Engineering (3 EC) 8. Structured Electronic Design (5 EC) 9. Bioelectricity (3 EC) 10. Sensors and Actuators (4 EC)

1. Imaging Systems (6 EC) 2. Acoustical Imaging (6 EC) 3. Medical Visualization (5 EC) 4. Machine Learning (6 EC)

Free elective courses The number of ECTS depends on the courses chosen from the second list of obligatory courses

Second year Graduation 60 EC

1. Internship (15 EC) 2. Student Colloquia (1 EC) 3. Literature & Introduction Colloquium (2 EC) 4. Literature Study (10 EC) 5. Thesis, Colloquium & Defence (32 EC)

4.3 First year (60 EC) The first year of the program consists of obligatory courses for all tracks (14 EC), obligatory courses for each track, and free elective courses. There are two lists of track-specific obligatory courses. The students of each track have to follow all the courses in the first list (24-25 EC) and a selection of three (two for Medical Physics) courses from the second list of obligatory courses. The general goal of these courses is to provide students a solid understanding of fundamentals of the relevant scientific topics as well as the state-of-the-art aspects of biomedical engineering that will allow them to undertake current and future challenges in this multidisciplinary field successfully. The list of obligatory and elective courses and are provided for this purpose in Chapter 8. These courses are a combination of both biomedical and engineering courses. Biomedical courses are taught by engineers and clinicians. Clinicians discuss clinical issues and explain their viewpoints, while also covering progress in clinically-related research. Several medical courses can be taken within the educational program of two of our clinical partner universities, Leiden University Medical Centre and the Erasmus Medical Centre Rotterdam. The students may list these medical courses to a maximum of 6 EC in their Individual Study Program. From the engineering viewpoint, the emphasis is placed on technical


and biophysical aspects, such as the latest advances in design, modeling and simulation, all the time relating this to the engineering background of the students. 4.3.1 Individual Study Program (ISP) All newly enrolled students need to register their program with selected courses using a prescribed template, which can be found on Brightspace (https://brightspace.tudelft.nl) under the heading ‘Master Biomedical Engineering’. Please check the Study Guide to ensure that your program meets the requirements, check your calendar for conflicting lecture times and to spread your study load evenly over the year, and consult the track/master coordinator to ensure that you optimally prepare for your study. The template needs to be signed by the track coordinator and by the student, and the original signed form shall be delivered to the Service Point 3mE for formal registration. Please send a scan of the signed form to the Master Coordinator ([email protected]).

4.4 Second year (60EC) The second year starts with an internship in a biomedical research group or biomedical company. The remainder of the year is taken up with a literature survey and a master thesis project. The traineeship and literature survey may be undertaken in any order. In general, assignments are carried out individually. It is best if the literature survey, traineeship and master thesis project are in the same field of research. Students shall discuss and plan the internship, literature survey and master thesis project with their graduation supervisor. 4.4.1 Internship in a hospital, industry or other research institute (15 EC) Over the course of their internship, students undertake a project task defined in consultation with the host institute. It is recommended that Dutch students undertake their internship abroad. The faculty overseeing the Biomedical Engineering master program will support student initiatives for study abroad, or will actively help in finding host institutions. The internships should culminate in a report. As it is difficult to evaluate internship achievements because conditions vary widely and as the aims of an internship are fulfilled more on a process level than on a product level, the student does not receive a grade but a general assessment. Important! Traineeships are usually arranged via one of the staff members in the student’s chosen track. Students are encouraged to contact the graduation supervisor at the start of the traineeship selection process. This helps to avoid problems later on: the track coordinators have a good overview of institutes and companies within their line of work and are in a position to judge whether or not the chosen institute or company is suitable. The graduation supervisor must give his approval before traineeships are started. Please, carefully check the information provided at https://www.tudelft.nl/en/student/faculties/3me-student-portal/education/related/student-forms/msc-forms/ Use the Internship Application Form which can be found on this web site: https://www.tudelft.nl/en/student/faculties/3me-student-portal/education/master/internships/ 4.4.2 Literature survey (10 EC) It is required that students do their literature survey in the same research field as their master thesis project. The literature survey will finish with a report and presentation in a seminar attended by staff and fellow students (see 4.4.4 Literature and Introduction colloquium). The students receive a grade for their literature survey report. 4.4.3 Master thesis project (32 EC) The master thesis project is the final part of the BME program. Ideally, the project is undertaken in collaboration with a clinical partner (Leiden University Medical Center (LUMC), Erasmus Medical Center


(ERASMUS MC) Rotterdam, the Academic Medical Center (AMC) Amsterdam), or the Free University (VUMC) Amsterdam. Regardless of whether thesis work is carried out in Delft or at the premises of the clinical partner, many MSc students will have a clinical tutor and a technical tutor. Students then prepare the MSc thesis as a project report. Thesis work is evaluated by way of an oral presentation (graduation colloquium) by the candidate and an oral examination before an MSc examination committee composed of at least three scientific staff members, including the thesis supervisor and one staff member from outside the research group. The examination committee may also include external examiners from research institutes or from industrial partners. 4.4.4 Literature and Introduction colloquium (2 EC) In multidisciplinary research, it is essential that students have good communication skills. Each student must, therefore, give two oral presentations: (i) literature & introduction colloquium, and (ii) graduation presentation, as part of their training in delivering a clear message to public from a different background. For the literature & introduction colloquium, the students should present the main findings of their literature study as well as an outlook into the master thesis project, providing an outline of the project goals, methodology and the research plan of the thesis project. The literature & introduction colloquium is organized over the entire study year, each student is evaluated by two to three specialists such as staff members, post-docs or PhD students. For each presentation, a grade will be given. 4.4.5 Student colloquia (1 EC) The presentations provide an excellent overview of the different research lines within the field of Biomedical Engineering at the Delft University of Technology and its affiliates. As such attending these presentations is encouraged for all students in the master BME, especially for those in search of an MSc-thesis topic. For this reason, each student is required to attend at least ten different seminars (each one consists of multiple presentations). After completion of ten seminars, the student will receive 1 EC.

4.5 Student interviews We feel that it is essential that students know what is expected of them, and that students let us know if there are problems within the study program so that we can make improvements. At the beginning of the academic year, a central presentation will be given, in which new students will be given a thorough introduction to the BME program, and where new students can meet each other. Following this presentation, an individual study program (ISP) will be drawn up in discussion with the master coordinator (see section 4.3.1). During the master program students complete anonymous questionnaires, usually issued at the end of each semester, which forms the basis for action taken to improve courses. Important! Student interviews are supplementary to, but not a replacement for, regular student-professor contact held on a more informal basis.


5 BME MSc program tracks Students starting the BME master program should be aware that the program is divided into three tracks: • Track I: Musculoskeletal Biomechanics (MB) • Track II: Medical Devices & Bioelectronics (MDB) • Track III: Medical Physics (MP) Important! At the beginning of the study program, students must choose their track. Switching between tracks is possible, but students should consider the obligatory courses required for each track. Chapter 5 describes the main focus of education and research in each track, and Chapter 6 describes admission requirements. More detailed information is provided during the yearly Introduction Event in the first week of the academic year. This five-day event presents the students with comprehensive information on the master Biomedical Engineering in general and on each of the track in particular. At the end of the event, the participants will be able to make an educated choice for a track and to compose the Individual Study Program accordingly. As students of the Biomedical Engineering master program come from many different previous educations and have many different nationalities, the Introduction Event also aims at the community building.


5.1 Track I: Musculoskeletal Biomechanics (MB) Coordinator: Prof.dr. DirkJan Veeger E-mail: [email protected] Tel: +31 (0)15 27 89530 Room: 34.E-1-250 Department of Biomechanical Engineering Faculty of Mechanical, Maritime and Materials Engineering (3ME) Overview We are living in a very demanding society in which people need increasing help to sustain their mobility and vitality throughout their lifetime. This track is focused on understanding the biomechanics of the musculoskeletal system with the aim to improve the vitality of healthy people, enhance the performance of sports professionals and to treat the patients suffering from musculoskeletal disorders and diseases. Therefore, the track is focused on relevant tissue biomechanics, biophysical models of muscles and joints, human motion control, interactions between the biological systems (including brain) and (electro)mechanical devices (e.g., neurorehabilitation robots, haptic interfaces, external prostheses, orthoses) as well as an assessment of the effects of sport equipment on the resultant performance. Students following this track will acquire the fundaments knowledge and research skills for solving increasingly complex and important challenges associated with human movement and control. Courses and research assignments focus on human movement analysis, musculoskeletal modelling, biomechatronics, identification of the (reflexive) control loops in the musculoskeletal system, human-machine interaction, biomaterials, mechanism design, and control theory, 3D printing.


5.2 Track II: Medical Devices and Bioelectronics (MDB) Coordinator: Prof.dr.ir. Wouter Serdijn E-mail: [email protected] Tel.: +31 (0)15 27 81715 Room: HB 18.310 Bioelectronics Department of Microelectronics Faculty of Electrical Engineering, Mathematics and Computer Science (EWI) Overview This track provides an integrated platform to enable development of advanced medical devices including biomaterials, design models and fabrication processes for implantable devices, biosensors, medical instruments, external prostheses, orthoses, as well as diagnosis and disease monitoring systems. From novel multifunctional biomaterials to device design and prototype fabrication, and finally testing of the devices in clinically relevant environments, the students are provided the needed theoretical knowledge and are then challenged to prove their concepts by working in state-of-the-art research laboratories. Multidisciplinary teams of teachers and researchers are involved in this track to integrate the relevant topics and provide a focused program. A wide range of medicals devices is covered. That include: biomaterials and implants able to repair and regenerate diseased tissues, fabricated by integrated technologies involving 3D printing, micro/nanofabrication and surface biofunctionalization, instruments for minimally invasive surgeries, virtual reality trainers and simulators with force/haptic feedback, prostheses, flexible and stretchable electronics and sensor microsystems for medical devices are in the focus of the education and research program of this track. As already confirmed, the students following this track acquire unique multidisciplinary expertise that makes them ready to face the challenges encountered by the biomedical companies active in these fields as well as by the clinicians and research teams in hospitals, academia and research institutes worldwide. Such specialists represent the guarantee for finding the solution of ‘tomorrow’ related to medical devices for healthcare systems.


5.3 Track III: Medical Physics (MP) Coordinator: Dr. Frans Vos E-mail: [email protected] Tel: +31 (0)15 27 87133 Room F266 Quantitative Imaging Group Department of Imaging Physics IST/Quantitative Imaging Faculty of Applied Sciences (TNW) Secretary: A. van Beek; Tel: +31 (0)15 27 81416, E-mail: [email protected] Overview Medical Physics is aimed at the application of physical methods in health care. Medical physicists are responsible for the standardization, calibration, and purchase of medical instruments, in close cooperation with medical and paramedical professionals. Furthermore, they are responsible for the accuracy and safety of physical methods applied in hospitals for diagnosis and therapy. In the BME Medical Physics track emphasis is placed on Medical Imaging and Radiotherapy. In Medical Imaging methods such as Computed Tomography (CT), Magnetic Resonance Imaging (MRI), and Nuclear Medicine imaging are providing high-quality 3D and 4D information of the human anatomy, but also of its function and its changes over time. The high quality of these images and resulting diagnostic information must be balanced against factors such as acquisition time and radiation burden to the patient. In radiotherapy, medical physicists play a major role in clinical, technical and biophysical concepts resulting in optimized treatment planning. Medical physicists are often involved in research. As in each BME track, graduates must show competence in cooperating with medical specialists, giving feedback on problems as well as on providing solutions. Professional opportunities lie in medical research, clinical support, and interaction with suppliers and manufacturers of the various devices for acquisition and processing of medical images as well as for providing state-of-the-art radiotherapy.


5.4 Annotation Entrepreneurship Students may include additional courses on Entrepreneurship in their program and select a Master Assignment with Entrepreneurial aspects. The Entrepreneurship annotation will be mentioned on the MSc degree (see www.dce.tudelft.nl).

5.5 Honours Program The Honours Program Master (HPM) will allow individual students to excel and thus deliver a performance that is significantly above the performance of average students. HPM students will be producers/directors of their own master program, rather than being a consumer of a program that already exists. In addition to the regular master program, an additional 20 ECTS needs to be earned, and there is a very large freedom in how to obtain these extra 20 ECTS. The HPM is intended for students that:

• finished their bachelor education within 4 years with an average grade of at least 7,5 • have another reason to participate

For details regarding the content of the program, the application procedure, and the selection criteria, please, check https://www.tudelft.nl/onderwijs/opleidingen/honours-programme-delft/honours-programme-master/. For more information, please contact [email protected].


6 Admission The content of the bachelor degree and results will be evaluated for each candidate. The intake committee of the Faculty 3mE is responsible for this selection.

6.1 Admission for students with an academic bachelor degree Students with a Dutch academic Bachelor degree listed in Appendix A (more information will follow) can enter the MSc program. Students with another Dutch academic Bachelor degree may be admitted on an individual basis after completion of a pre-master program. International applicants with an academic Bachelor degree need to follow the admission and application process as outlined on the BME website: https://www.tudelft.nl/onderwijs/opleidingen/masters/bme/msc-biomedical-engineering/admission-and-application/with-an-international-degree/ Important! The tracks within the master BME are tailored to fit the [TUD] bachelor programs in Mechanical Engineering, Applied Physics, or Electrical Engineering. As a result, other bachelor programs do not always perfectly match a track. In these cases, it is the student’s responsibility to acquire the prerequisite knowledge. Please contact the BME coordinator [[email protected]] for more information and advice.


6.2 Admission for students with a bachelor degree from a Dutch school for higher vocational education (HBO)

6.2.1 Introduction Candidates with a Dutch HBO Bachelor in Electrical Engineering, Mechanical Engineering, Applied Mathematics, Applied Physics, Aerospace Engineering or Human Kinetic Technology are eligible for admission. The candidate must have completed the Bachelor program within 4 years with good results. Students with a Dutch HBO Bachelor degree in areas not mentioned above can be admitted on an individual basis. Please contact the BME coordinator [[email protected]]. An additional pre-master program must be completed before candidates are formally admitted to the MSc program. In the pre-master program, a number of courses from the second year of the academic bachelor program must be followed. These additional requirements will ensure that students have an entrance level at least comparable to that of the second course year of the academic bachelor program that forms the basis for the specific track, i.e. Mechanical Engineering for track Musculoskeletal Biomechanics, Mechanical Engineering or Electrical Engineering for Medical Devices and Bioelectronics, and Applied Physics for Medical Physics. The coordinator of the chosen track may also require that a number of third-year courses from the bachelor program are followed. Important! All courses in the pre-master program are taught in Dutch. Candidates are formally admitted only to the pre-master program. It is not allowed to participate in MSc-courses before the pre-master program is completed. Final admission to the MSc program is granted after completing the pre-master program. The proposed pre-master program must be approved by the Examination Committee. As explained above, it is important to note that the pre-master program gives admission to specific track within the BME MSc program. This means that students must choose their track at the start of their pre-master program. 6.2.2 Pre-master program for students with an HBO degree in Mechanical Engineering,

Aerospace Engineering or Human Kinetic Technology (Bewegingstechnologie) The students with an HBO degree in Mechanical Engineering, Aerospace Engineering or Human Kinetic Technology (Bewegingstechnologie) may enroll in one of the following tracks: Musculoskeletal Biomechanics or Medical Devices and Bioelectronics after they have followed a pre-master program of courses that will give them the same level of knowledge as an academic BSc graduate in Mechanical Engineering. This pre-master program is almost the same as the pre-master program for the MSc in Mechanical Engineering. This program totals an additional 28 EC. Advice on this pre-master program can be obtained from Lourdes Gallastegui, [email protected]


Table 6.1. Mechanical Engineering pre-master program Code Lecture hours Course name EC WB2630* 8/0/0/0 Advanced Mechanics 6 WB2631T2 S* #/0/0/0 Finite Element Methods (FEM) 1 WB3240 0/0/4/0 Systeem- en Regeltechniek 6 WI1708TH1 4/0/0/0 Analyse 1 TH 3 WI1708TH2 0/4/0/0 Analyse 2 TH 3 WI1708TH3 0/0/4/0 Analyse 3 TH 3 WI1808TH1 4/0/0/0 Lineaire Algebra 1 3 WI1909TH 0/4/0/0 Differential Equations 3 Total 28

* Students are encouraged to prepare by careful reading material from the corresponding first-year courses: WB1630wb-14 Statica, WB1631-14 Sterkteleer1, and WB1632 Dynamica.

# Practical work + assignments. 6.2.3 Pre-master program for the students with an HBO in Applied Physics The bachelor graduates with a vocational degree (HBO) in Applied Physics may enroll in the Medical Physics track after they have followed a pre-master program of courses that will give them the same level of knowledge as an academic BSc graduate in Applied Physics. Therefore, this pre-master program is similar to the pre-master program for Applied Physics. This program totals an additional 27 EC. Table 6.2. Applied Physics pre-master program

Code Course name EC TN2054 Electromagnetism 6 TN2345 Introduction to Waves 3 TN2421 Optics 3 TN2545 Systems and Signals 6 WI1142TN Linear Algebra part 1 3 TN2244WI Linear Algebra and Differential Equations 6 Total 27

6.2.4 Pre-master program for students with an HBO degree in Electrical Engineering The students with an HBO degree in Electrical Engineering may enroll in the Medical Devices and Bioelectronics track after they have followed a pre-master program of courses that will give them the same level of knowledge as an academic BSc graduate in Electrical Engineering. This pre-master program is exactly the same as the pre-master (or bridging) program for Electrical Engineering – track Microelectronics. For further information E-mail: [email protected] Part of the pre-master program is filled in on an individual basis. Therefore, it is essential that students make an appointment with Prof. Wouter Serdijn at the start of the year ([email protected]). They can also provide students with any information missing in Table 6.3.


Table 6.3. Electrical Engineering pre-master program Code Course name EC EE3P11 Elektromagnetisme 5 EE3C11 Elektronica 5 ET8027 Solid State Physics 3 EE2S11 Signals & Systems 5 WB3240 Systeem- en Regeltechniek 6 WI1000 Refresher Track 0 WI1708TH1 Analysis 1 3 WI1708TH2 Analysis 2 3 WI1708TH3 Analysis 3 3 WI1807TH1 Linear Algebra 1 3 WI1807TH2 Linear Algebra 2 3 Total 39

6.3 Admission for students still in their academic bachelor program Students who have not yet finished their bachelor program are not permitted to take examinations in the MSc program [harde knip].


7 Teaching in Leiden (LUMC) and Rotterdam (Erasmus MC)

Part of the master program can be taken at Leiden University Medical Centre or the Erasmus Medical Centre (Rotterdam). Students have numerous opportunities to do their internship or master thesis assignment at one of these two medical centers; and they may also take biomedical courses as listed in Table 8.9. Summaries of these courses can be found at www.studiegids.tudelft.nl. In Leiden, the focus is on courses for the first year of the master. In Rotterdam the focus is on courses in the second year of the master; although the courses can be taken separately in the first year of the master, they are also integrated into an internship program that is offered to students. Students may choose medical courses at LUMC and Erasmus MC to a total of no more than 6 EC. Any additional EC points will come on top of the total of 120 EC needed to accomplish the MSc BME program.

7.1 Courses in Leiden Leiden University Medical Centre offers several courses to Biomedical Engineering students. These 3 to 4-week classes will be followed alongside (bio)medical students to encourage interaction between future colleagues. The schedule of courses taught at LUMC is optimized for Leiden students. Therefore, these courses can and will have an overlap with Delft courses and sometimes even with the Delft examination period. Students should ensure that they check carefully that attending a full-time course in Leiden will not interfere too much with the rest of their study program. At LUMC, teaching is based on "doelstellingengestuurd" learning. The courses offer lectures (overview, patient demonstration, or response), workgroups, and practicals. Self-study is guided by a course book that includes self-study-assignments. In workgroups, the material is discussed in more detail under the guidance of a tutor. Each course is examined by a 3-hour written examination. Detailed information on the courses and their time schedule can be found at https://www.lumc.nl/org/studentenportaal/. The latest admission procedures for TU Delft students can be found at https://www.lumc.nl/org/studentenportaal/geneeskunde/toelating/gaststudent/. Students must register for courses at least 6 weeks in advance; however, it is appreciated if students can make their choice right at the beginning of the academic year. Each course has its own module on the LUMC blackboard, through which the course-coordinator communicates with students. Students who have been granted admission to the courses will get access to the LUMC blackboard environment.

7.2 Courses in Rotterdam A general medical course (7 EC, BM41080) on “Disorders of Environment & Interior” is taught each year at the Erasmus University in the first semester and covers the anatomy and physiology of selected organ systems (e.g. lung, kidney and bladder). Since this course is also part of the general medical training program it encourages interaction with medical students/colleagues.


8 BME master courses BME students select their master courses according to the chosen track. For each track, there are three different types of courses:

A. Obligatory courses for all tracks (³ 14 EC) B. Track specific obligatory courses

B1. First list of obligatory courses (24-25 EC) B2. Second list of obligatory courses (ca 10 EC)

C. Free elective courses (ca 10-11 EC)

8.1 Obligatory courses all tracks The following courses are obligatory for all BME students (Table 8.1): Table 8.1. Obligatory courses all tracks (³14 EC) Course code Course name Lecture hours EC BM41045 Experimental Design, Statistics, and the Human 0/0/4/0 2

BM41055 Anatomy & Physiology (*) (only for students with technical background) 2/2/0/0 4

BM41065 Medical Technology I (Diagnostic devices) & Health Care Systems 4/4/0/0 5 WM1401TU Ethics of Healthcare Technologies 0/0/0/x 3

Total obligatory courses all tracks 14 (*) The students who have a background in Biology, Biomedical Engineering/Technology, Biomedical Sciences, Biopharmacy, Clinical Technology, Human Movements Sciences, Medical Natural Sciences, Medicine, or Veterinary Medicine are not allowed to follow the course BM41055-Anatomy & Physiology. They have to choose another course instead.

8.2 Track specific obligatory courses There are two lists of track-specific obligatory courses. The students of each track have to follow all the courses in the first list (24-25EC) and a selection of three (two for Medical Physics) courses from the second list of obligatory courses.


8.2.1 Courses Musculoskeletal Biomechanics track The students should take all the obligatory courses from Table 8.2. Table 8.2. First list of obligatory courses (25 EC): Course code Course name Lecture hours EC BM41040 Neuromechanics & Motor Control 0/0/4/4 5 BM41090 Computational Mechanics of Tissues and Cells 0/0/3/3 6 ME41045 Tissue Biomechanics of Bone, Cartilage and Tendon 2/0/0/0 3 ME41065 System identification & Parameter Estimation 2/2/0/0 7 ME41085 Biomechatronics 0/0/2/2 4

Obligatory courses this track 25 The students should choose a number of three courses from Table 8.3. They can base their choices on specific focus areas, such as: biomechatronics, tissue biomechanics, sports engineering, prosthetics and orthotics, etc. Table 8.3. Second list of obligatory courses: Course code Course name Lecture hours EC BM41035 Biomaterials 0/4/0/0 4 BM41155 3D printing 0/0/4/0 4 ME41035 Special Topics in Sports Engineering 0/0/0/4 3 ME41055 Multibody Dynamics B 0/0/2/0 4 ME41070 The Human Controller 0/0/0/4 3 ME41075 Biomedical Engineering Design 0/2/0/0 4 ME41080 Man-machine systems 0/4/0/0 4 SC42000 Control System Design (or the more extensive course: SC42015 - 6EC) 4/0/0/0 3


8.2.2 Courses Medical Devices and Bioelectronics track The students should take all the obligatory courses from Table 8.4. Table 8.4. First list of obligatory courses (24 EC): Course code Course name Lecture hours EC BM41035 Biomaterials 0/4/0/0 4 BM41050 Applied experimental methods 0/0/0/2 4 BM41095 Medical instruments A: Clinical challenges and engineering solutions 4/0/0/0 3 BM41155 3D printing 0/0/4/0 4 EE4555 Active Implantable Biomedical Microsystems 0/0/0/4 5 ET4127 Themes in Biomedical Electronics 0/0/3/0 4

Obligatory courses this track 24 The students should choose a number of three courses from Table 8.5. They can base their choices on specific focus areas, such as: medical instruments, biomaterials and implants, bioelectronics and bioelectricity, prosthetics and orthotic, etc. Table 8.5. Second list of obligatory courses: Course code Course name Lecture hours EC BM41075 Regenerative medicine 0/0/0/4 4 BM41090 Computational Mechanics of Tissues and Cells 0/0/3/3 6 BM41100 Medical instruments B: Quality assurance in design 0/0/3/0 3 ME41045 Tissue Biomechanics of Bone, Cartilage and Tendon 2/0/0/0 3 ME41065 System identification & Parameter Estimation 2/2/0/0 7 ME41075 Biomedical engineering design 0/2/0/0 4 EE4C02 System Engineering 0/0/4/2 3 EE4C09 Structured Electronic Design 4/0/0/0 5 ET4130 Bio-electricity 0/0/3/0 3 ET4257 Sensors and Actuators 0/3/0/0 4


8.2.3 Courses Medical Physics track The students should take all the obligatory courses from Table 8.6. Table 8.6. First list of obligatory courses (24 EC): Course code Course name Lecture hours EC AP3132 D Advanced Digital Image Processing 0/0/4/4 6 AP3232 D Medical Imaging, Signals & Systems 0/0/2/2 6 AP3371TU D Radiological health physics 0/0/8/8 6 AP3582 Medical Physics of Photon and Proton Therapy 0/0/2/2 6

Obligatory courses this track 24 The students should choose a number of two courses from Table 8.7. Specific focus areas to be considered are: medical imaging and radiotherapy. Table 8.7. Second list of obligatory courses: Course code Course name Lecture hours EC AP3121 D Imaging Systems 4/4/0/0 6 AP3531 Acoustical Imaging 0/0/2/2 6 IN4307 Medical Visualization 6/0/0/0 5 IN4320 Machine Learning 0/0/2/2 6


8.3 Free elective courses The students can add to their study program several elective courses (10-11EC) that are presented in Table 8.8. Table 8.8. Free elective courses: Course code Course name Lecture hours EC BM41060 Physiology and Engineering 0/0/0/2 3 BM41070 Medical Device Prototyping (limited capacity) 0/0/2/2 6 ME41095 Bio-inspired Design 4/4/0/0 4 ME46085 Mechatronic System Design 0/4/0/0 4 SC42090 Robot Motion Planning and Control 0/0/4/0 3 SC42095 Digital Control 0/4/0/0 3 CIE4353 Continuum Mechanics 4/4/0/0 6 CIE5123 Introduction to the Finite Element Method 0/0/6/0 4 CIE5142 Computational Methods in Non-linear Solid Mechanics 0/0/0/4 3 EE4C01 Profile Orientation and Academic Skills 2/2/0/0 3 EE4C03 Statistical Digital Signal Processing 4/0/0/0 5 EE4C08 Measurement and Instrumentation 4/0/0/0 5 EE4520 Analog CMOS Design I 0/3/0/0 3 EE4585 Semiconductor Device Physics 0/4/0/0 5 ET4252 Analogue IC Design 0/0/3/0 4 ET4260 Microsystem Integration 0/0/0/3 4 ET4277 Microelectronics Reliability 0/0/3/0 4 ET4289 Integrated Circuits and MEMS Technology 0/0/3/0 4 ET4386 Estimation and Detection 0/4/0/0 5 ID4010 Design Theory and Methodology 3/0/0/0 3 IN4085 Pattern Recognition 6/6/0/0 6 IN4182 Digital Audio and Speech Processing 0/0/0/4 6 Apart of the courses listed in Table 8.8, the students can choose as electives any other courses from the list of mandatory courses of other tracks. There are many more courses at TU Delft that students may include in their study program than those listed in Table 8.8. Furthermore, students may select master courses from other universities in and outside the Netherlands. Students wishing to take courses that are not listed should consult their track/master coordinator. Important!

• Students may select medical courses at LUMC and the Erasmus MC worth a total of no more than 6 EC. Any additional EC points will come on top of the total of 120 EC needed to complete the MSc BME program.


Table 8.9. Biomedical and medical courses at LUMC (see section 7.1) & Erasmus MC (see section 7.2). University Course code

TUD Course name Lecture hours EC Language

Leiden BM41000 301122000Y: Hersenen en Aansturing May - June 7 Dutch

Leiden BM41005 3112055PPY: Introduction to the Neurosciences Jan - Feb 6 Dutch

Leiden BM41010 301220000Y: Vraagstukken Beweging Dec - Feb 9 Dutch Leiden BM41015 301121000Y: Sturing en Stofwisseling Apr - May 7 Dutch Leiden BM41020 301221000Y: Buik Feb - Mar 8 Dutch Leiden BM41025 Surgery for Engineers Nov - Jan 2 English

Leiden BM41160 3112065PPY: Design and Analysis of Biomedical Studies (DABS) – Statistical research methods

Feb - Mar 6 Dutch

Rotterdam BM41080 GENBA1B1: General Course on Disorders of Environment & Interior Sep - Oct 6 Dutch

Note These medical courses are not considered when applying for the post-initial education

program for Clinical Physicist.


9 Study and traineeship abroad Study abroad offers a wealth of attractive prospects. Students become acquainted with a different (organizational) culture, university life, and educational system. In addition to enlarging their personal network, students learn to live in a foreign environment and improve their language skills. To put it briefly, a period of study abroad will make a valuable contribution to any student’s personal education and will pay dividends in the search for a job. Students wishing to study at a foreign university may make use of one of the many exchange agreements held with European and non-European universities. Under the terms of these agreements, students do not pay tuition fees to the foreign university. Grants are also available to help finance the added cost of staying abroad. Extensive information on studying abroad is available from Back Office International Programs at the Student Facility Centre, including information on all universities with which an exchange agreement exists, financing study abroad, and student travel reports. Further information is available on https://www.tudelft.nl/en/student/faculties/3me-student-portal/education/related/exchange-study-abroad-3me/ Internships abroad are highly encouraged, and your track coordinator/supervisor may help to arrange it. Please, also consult the International Office at 3mE for practical issues. Students may, with prior approval of the track coordinator, select master courses at other (foreign) universities as part of their study program. If you have a clear idea about where you would like to go, you should seek the advice of the International Exchange Coordinator about your program at the foreign university and the recognition of your results at the host university. Your graduation professor will assess your work on your return according to the guidelines you agreed upon before departure. The foreign program should contribute a maximum of 12 EC to your MSc program. Studying abroad requires a lot of personal preparation. Students should account for a preparation period of preferably one year, but at least half a year. Students are advised to contact the International Office at 3mE: Mrs. Sara van Dalen-Bus or Mrs. Marion van Eijck Room A-1 Mekelweg 2, 2628 CD Delft Tel: +31 (0)15 27 83856 or +31 (0)15 27 83689 E-mail: [email protected]


10 Enrolling for courses and tests The latest information can be found at https://www.tudelft.nl/en/student/faculties/3me-student-portal/ Students are usually required to enrol for courses and tests. There are different procedures for both.

10.1 Courses Students may register for specific courses on Brightspace (https://brightspace.tudelft.nl). Most of the communication between lecturers and students takes the form of Brightspace announcements, along with exchange of information, assignments and reports.

10.2 Tests Enrolling for tests is obligatory and can be done on the Osiris site, accessible through Brightspace. Students should enrol at least two weeks before tests take place, otherwise tests will not be accounted for by the lecturer. If a student has registered but decides not to do the test, the student must cancel at least three working days before the test is due to take place.


11 Organization

11.1 Faculty of 3mE 3mE is an abbreviation of Mechanical, Maritime and Materials Engineering. The 3mE Faculty offers the master programs Biomedical Engineering (BME), Technical Medicine (TM), Materials Science and Engineering (MSE), Mechanical Engineering (ME), Marine Technology (MT), Systems and Control (SC) and Offshore & Dredging Engineering (ODE).

11.2 Organizational structure As mentioned above, the BME programme at TU Delft is an interfaculty programme jointly delivered by three faculties: Faculty of 3mE, Faculty of Applied Sciences, and Faculty of Electrical Engineering, Mathematics and Computer Science. The Faculty of 3mE coordinates the programme. It is one of the eight faculties at TU Delft and is structured as follows with regards to education: • The Dean is responsible for both research and education, as well as for operations and finance. The

Dean is supported by a Management Team, which consists of the heads of all seven departments of the Faculty, the Director of Education and the Faculty’s secretary general.

• The Director of Education is responsible for the overall educational processes, education policies and education quality management of the Faculty, and presides over the Educational Board of the Faculty, which consists of all Directors of Studies and the manager of the department of Education and Student Affairs.

• The Director of Studies is responsible for the content and quality of the programme, and is supported by a Master Coordinator, who monitors the running of the programme and processes on a daily basis. Together they form the Programme Management.

• The Board of Examiners (BoE) determines in an objective and professional way whether a student meets the conditions set by the Teaching and Examination Regulations with regards to the knowledge, insight and skills required to obtain a degree. The Faculty hosts two Boards of Examiners: one for the programmes Clinical Technology and Technical Medicine, and one for the eight other programmes in the Faculty, including the BME programme.

• The Board of Studies (BoS) is responsible for the quality assurance of the study programme. It provides solicited and unsolicited advice on matters regarding the educational quality and the Teaching and Examination Regulations. The Faculty hosts eight Boards of Studies. The BME programme has its own BoS, which consist of four student members and four staff members. The programme’s Director of Studies and the Master Coordinator participate in the BoS meetings as guests.

• The department of Education and Student Affairs (ESA) offers support to the teaching staff and the students of 3mE. ESA supports the staff with scheduling, educational advice, student admission and defence organisation. To students, ESA offers academic counselling and support regarding studying abroad. Furthermore, ESA hosts the secretariat of both BoEs, the educational coordinators, the quality assurance coordinators and is responsible for the information supply to students at Faculty level.

11.3 Education support staff The education support staff support the Mechanical Engineering programs and provide information for students relating to the study of Mechanical Engineering. The education support staff comprises the following persons: Prof.dr. Hans Hellendoorn Director of Education [email protected] Tel: +31 (0)15 27 89007 Drs. Geerlinge Pessers Head Education & Student Affairs [email protected] Tel: +31 (0)15 27 85451 Marion van Eijk Coordinator International Office (exchange students) [email protected] Tel.: +31 (0)15 27 83689


Sara van Dalen-Bus Coordinator International Office [email protected] Tel.: +31 (0)15 27 83856 Ewoud van Luik Coordinator Education [email protected] Tel: +31 (0)15 27 85734 Ir. Pelle Alons Coordinator Education [email protected] Tel: +31 (0)15 27 88186 Linette Bossen Quality Assurance [email protected] Tel.: +31 (0)15 27 85014 Drs. Daniëlle Rietdijk Quality Assurance [email protected] Tel: +31 (0)15 27 84923 Judith de Kruif Quality Assurance [email protected] Tel: +31 (0)15 27 82176 Drs. Lourdes Gallastegui Academic Counsellor [email protected] Tel: +31 (0)15 27 86591 Drs. Pauline van der Sman Academic Counsellor [email protected] Tel: +31 (0)15 27 83350 Drs. Lieke Defourny-Smits Academic Counsellor [email protected] Tel: +31 (0)15 27 84645 Drs. Tineke Dijkstra Academic Counsellor [email protected] Tel.: +31 (0)15 27 82174 Drs. Evert Vixseboxse Academic Counsellor [email protected] Tel: +31 (0)15 27 82996 Drs. Peggy Eskikilic [email protected] Daniëlle de Jong

Academic Counsellor Tel: +31 (0)15 27 85152 Secretary

[email protected] Tel.: +31 (0)15 27 3570 Esther Kroes Secretary [email protected] Tel.: +31 (0)15 27 7884 xxxx Board of Examiners [email protected] Tel.: +31 (0)15 27 8xxx Annet Schollaart [email protected]

Course schedules Tel: +31 (0)15 27 85577

Gerard van Vliet Coordinator IWS [email protected] Tel.: +31 (0)15 27 89281

Address: Mekelweg 2, 2628 CD Delft Location A-1, first floor Tel: +31 (0)15 27 85499

11.4 Board of Studies The Board of Studies advises the Dean and the Director of Education on the contents and the structure of the study program and examinations. The BoS consists of four lecturers and four students. Chairman: Dr. John J. van den Dobbelsteen Tel: +31 (0)15 27 89515 E-mail: [email protected] Secretary: Angelique Timmerman Mekelweg 2 Room E-1-200 2628 CD Delft Tel: +31 (0)15 27 86400 E-mail: [email protected]


11.5 Board of Examiners The Board of Examiners consists of lecturers involved in the study program and is responsible for setting the rules and regulations for examinations and the assessment of examination results. Requests for changes to or deviations from the study program should be addressed to the Board of Examiners. Chairman: Prof.dr.ir. Paul Breedveld Tel: +31 (0)15 27 85232 E-mail: [email protected] Secretary - xxxxx Tel: +31 (0)15 27 xxxxx E-mail: xxxxx

11.6 Student association The master program has an active student association, “Antoni van Leeuwenhoek”, which organizes meetings, break-out sessions, and other social events on a regular basis. Information can be found on dispuutavl.nl and on the AvL Brightspace page.

11.7 BME program management The programme management team of the BME MSc program is formed of the Director of Studies and the Master Coordinator. The Director of Studies is responsible for the content and quality of the programme, and is supported by a Master Coordinator, who monitors the running of the programme and processes on a daily basis. Director of Studies: Prof.dr. Amir A. Zadpoor ([email protected]) Master Coordinator: Dr.ir. Iulian Apachitei ([email protected]) Secretary: Angelique Timmerman Mekelweg 2 Room E-1-200 2628 CD Delft Tel: +31 (0)15 27 86400 E-mail: [email protected] The MSc coordinator is the person to approach for questions or problems related to the individual study program and for monitoring progress. Every student can consult the MSc coordinator to draw up an individual study program made up of the following: obligatory courses, current ideas on a topic for the thesis project, free elective courses bridging the gap between the obligatory courses and the thesis project. Students submit their plans for approval to the Board of Examiners. In order to finish the program in two years, students should plan to take an average of 30 credits of courses per semester. At the end of the first-year students will meet with the MSc coordinator to discuss their progress and their plans for the remainder of the program. Students are also asked to fill in a questionnaire to evaluate the master program.

11.8 Academic counsellor The Faculty has five academic counsellors on hand to give assistance and advice to students regarding study-related questions or problems, or other issues which might influence a student’s ability to study. The academic counsellor functions as a sounding board and as a confidential consultant to students.


11.8.1 Individual help and advice Academic counsellors have no teaching responsibilities and can therefore devote themselves entirely to individual students in addressing problems which may be an obstacle to their study progress. Academic counsellors also are a member of many boards and have contact with lecturers, so they are kept up to date with the latest in the Biomedical Engineering program. Academic counsellors are also in contact with other student advisors and personal advisors at TU Delft and outside the University. 11.8.2 Personal circumstances During sessions with an academic counsellor, personal and intimate information will often come up. Students can be assured that this information will be kept confidential. This kind of information will only be used after consultation with the student in appeals to the TU or the Faculty. 11.8.3 Alerting the Examination Committee, professors, and other members of staff An academic counsellor may decide, under certain conditions, to alert the Board of Examiners or a professor to a specific student. Where necessary, the academic counsellor becomes an intermediary between TU Delft personal advisors: student, deans, psychologists and physicians. The extent to which the academic counsellor pays attention to a student is up to the student. The academic counsellor keeps an eye on the study progress of most students and calls them up if necessary, but it is strongly recommended that students contact the academic counsellor themselves when a question or problem comes up. Waiting often exacerbates the problem. The academic counsellors at the Faculty are available for any questions you might have. They also have their own areas of specialization.

11.9 Foreign Student Financial Support (FSFS) Delft University of Technology provides financial assistance to foreign students in the event that their studies are delayed due to special circumstances such as physical illness, physical or sensory disorders, mental problems, or insufficient organization of the educational program by the Faculty.


12 Further Information This study guide is the main information source for the study program. The website www.bme.msc.tudelft.nl always contains the most recent information. Detailed course information is available in the Digital Study Guide via www.studiegids.tudelft.nl or via https://brightspace.tudelft.nl - here it is not necessary to log in; go to the “Digital Study Guide” tab. Procedures and forms are available at https://www.tudelft.nl/en/student/faculties/3me-student-portal/education/related/student-forms/msc-forms/ The Course and Examination Regulations can be found here: http://www.wbmt2.tudelft.nl/onderw/Reglementen/2017-2018/OER-MSc-BME.pdf Regulations and Guidelines for the Board of Examiners here: http://www.wbmt2.tudelft.nl/onderw/Reglementen/2017-2018/RRvE-MSc.pdf


Appendix A List of Bachelor of Science studies that allow for a direct admission to the Master program in Biomedical Engineering 2018-2019:

Advanced Technology Aerospace Engineering Applied Earth Sciences Applied Mathematics Applied Physics Biomedical Engineering Civil Engineering Clinical Technology Computer Science and Engineering Electrical Engineering Human Movement Sciences Industrial Design Engineering Life Science and Technology Maritime Engineering Mechanical Engineering Medische Natuurwetenschappen Medische Wetenschappen en Technologie Molecular Science and Technology Nanobiology Physics Psychology and Technology


Appendix B - ISP form 2018-2019

STUDY PROGRAM IN MSc BIOMEDICAL ENGINEERING Track 1: Musculoskeletal Biomechanics (MB) Track: Track 2: Medical Devices and Bioelectronics (MDB) Track 3: Medical Physics (MP) Student name: Study number: Preliminary education:

FIRST YEAR: COURSES OBLIGATORY COURSES ALL TRACKS Course code Course name EC

Total obligatory courses all tracks ≥ 14 EC TRACK SPECIFIC OBLIGATORY COURSES

Course code Course name EC FIRST LIST OF OBLIGATORY COURSES 24/25 EC SECOND LIST OF OBLIGATORY COURSES (3 MB/MDB & 2 MP)

Total obligatory courses track FREE ELECTIVE COURSES ALL TRACKS

Course code Course name EC

Total courses ≥ 60 EC

SECOND YEAR: GRADUATION (ASSIGNMENTS) Course code Course name EC BM51015 Internship 15 BM51001 BME Student Colloquia 1 BM51002 BME Literature and Introduction Colloquium 2 BM51010 BME Literature Study 10 BM51032 BME MSc-thesis 32

Total of all assignments 60 60 EC

Total of complete program ≥120 EC

EC = European Credit. 1 EC = 28 hours study load Name of coordinator: Date: Signature coordinator: Signature student: Examination board:

…………………………………… …………………………………… …………………………………… Please hand in this form at the ServicePoint 3mE (keep a copy for your own administration)

biomedical engineering msc program study guide 2018 … · 2018-10-17 · biomedical engineering...

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