biomedical engineering biomedical engineering(bme) · . ... phy 131/133 4 bme 100 3 total 18 junior...

144 www.stonybrook.edu/ugbulletin

Fall 2008: updates since Spring 2007 are in redBIOMEDICAL ENGINEERING

FacultyDanny Bluestein, Associate Professor, Ph.D.,Tel Aviv University: Cardiovascular flowmechanics and pathologies; prosthetic devices.

Weiliam Chen, Assistant Professor, Ph.D.,University of Michigan: Gene therapy and drug delivery.

Ki Chon, Associate Professor, Ph.D., Universityof Southern California: Cardiac autonomic nervous system in normal and diseased states;renal autoregulatory dynamics; neuro-respirato-ry control; medical devices; clinical diagnosticand prognostic applications.

Richard Clark, Professor, M.D., University ofRochester: Tissue engineering; skin cell activation; tissue formation of healing cutaneous wounds.

Anil Dhundale, Assistant Professor, Ph.D.,Stony Brook University: Development of diagnostic and research products in biotech-nology, pharmaceutical, and medical devices;DNA microarray.

Shmuel Einav, Professor, Ph.D., Stony BrookUniversity: Blood-tissue interaction; vascularprosthetic devices.

Emilia Entcheva, Assistant Professor, Ph.D.,University of Memphis: Cardiac cellular electromechanics; cardiac tissue engineering;fluorescence imaging; computer simulations of cellular function.

Michael Hadjiargyrou, Associate Professor, Ph.D.,City University of New York: Molecular mecha-nisms of bone development and regeneration.

Stefan Judex, Assistant Professor, Ph.D.,University of Calgary: Adaptation response to mechanical stimuli at the organ, tissue, cellular and molecular levels.

Wei Lin, Research Assistant Professor, Ph.D.,Stony Brook University: Noninvasive assessment of bone quality; confocal acoustic scanning technology.

Mary Frame McMahon, Associate Professor,Ph.D., University of Missouri: Microvascularnetwork flow control; nanobiotechnology; tissue engineering of vascular structures.

Lilianne Mujica-Parodi, Assistant Professor,Ph.D., Columbia University: Limbic dysregula-tion in schizophrenia; physiological/cognitivecomponents of human arousal response; complex systems analysis.

Yingtian Pan, Associate Professor, Ph.D.,Huazhong University of Science andTechnology: Optical imaging of biological

tissue at the cellular level; diagnosis andassessment of tissue growth.

Yi-Xian Qin, Associate Professor, Ph.D., Stony Brook University: Fluid flow of porousstructures; ultrasonic-based diagnostics.

Clinton Rubin, Professor, Ph.D., University ofBristol: Adaptation of the skeletal system; therapeutic medical devices.

Balaji Sitharaman, Assistant Professor, Ph.D.,Rice University: Multifunctional nanobiosys-tems for simultaneous diagnostics and thera-peutics (theragnostics); multidimensionalsupramolecular biosystems for imaging, drugdelivery and tissue regeneration; nanobio-inter-face devices for tissue regeneration.

Helmut Strey, Assistant Professor, Ph.D.,Technical University, Munich: Characterizationof nanostructured materials for bioseparation;controlled drug delivery; biosensors; DNAsequencing applications.

Adjunct FacultyEstimated number: 8

Teaching AssistantsEstimated number: 16

The Department of BiomedicalEngineering offers the major inBiomedical Engineering, leading

to the Bachelor of Engineering (B.E.)degree. The Department also offers aminor in Bioengineering designed fornon-engineering students. (See the entryin the alphabetical listings of ApprovedMajors, Minors, and Programs for therequirements for the minor in Bio-engineering.) In a rigorous, cross-disci-plinary training and research environ-ment, the major program provides anengineering education along with astrong background in the biological andphysical sciences. It is designed to en-hance the development of creativity andcollaboration through study of a special-ization within the field of biomedicalengineering. Teamwork, communicationskills, and hands-on laboratory andresearch experience are emphasized.The curriculum provides students withthe underlying engineering principlesrequired to understand how biological

organisms are formed and how theyrespond to their environment.

Core courses provide depth within thebroad field of biomedical engineering.These are integrated with, and rely upon,course offerings from both the College ofEngineering and Applied Sciences and theCollege of Arts and Sciences. To achievethe breadth of engineering experienceexpected of Biomedical Engineeringgraduates, additional elective coursesfrom the College of Engineering andApplied Sciences are required of allBiomedical Engineering students.

The Department also offers a five-yearcombined B.E./M.S. degree, which can becompleted within one additional year ofstudies beyond the Bachelor’s degree.

The combined B.E./M.S. is intended toprepare high-achieving and highly-moti-vated undergraduate BME students foreither doctoral studies or a variety ofadvanced professional positions. Theprogram is highly selective with admis-sion based on academic performance aswell as undergraduate research. Juniorscan be admitted into the combineddegree program if they satisfy therequirements outlined in the GraduateBulletin. The requirements for the com-bined program are the same as therequirements for the B.E. and M.S.degree, except that two graduate 500-level courses replace two 300-levelelectives, so that six graduate credits are counted toward the undergraduatedegree.

Graduates are prepared for entry intoprofessions in biomedical engineering,biotechnology, pharmaceuticals, andmedical technology, as well as careers inacademia and government. Potentialemployers include colleges and universi-ties, hospitals, government, researchinstitutes and laboratories, and privateindustry.

Biomedical Engineering (BME)Major in

Biomedical EngineeringDepartment of Biomedical Engineering, College of Engineering and Applied SciencesCHAIRPERSON: Clinton Rubin UNDERGRADUATE PROGRAM DIRECTOR: Mary Frame McMahon UNDERGRADUATE PROGRAM ASSISTANT: Wendy Scharf OFFICE: HSC T18-030 PHONE: (631) 444-3821 E-MAIL: [email protected] ADDRESS: http://www.bme.sunysb.edu/bmeMinors of particular interest to students majoring in Biomedical Engineering: Biochemistry (BCH), Biology (BIO) Chemistry (CHE), Optics (OPT)

http://www.bme.sunysb.edu/bme

mailto:[email protected]

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Fall 2008: updates since Spring 2007 are in red

Program Educational ObjectivesThe undergraduate program in biomed-ical engineering has the following fivespecific program educational objectives:

1. Career Preparation: Our graduates willbe prepared to excel in bioengineering,bioscience, or medical disciplines inbasic and applied research, design, ortechnology development, representingthe fields of academics, government,medicine, law, or industry.

2. Professional Development: Our gradu-ates will emerge as recognized expertsin the field of biomedical engineering,and serve in positions of leadership inacademics, government, medicine, orindustry. Further, our alumni will func-tion successfully as principal membersof integrative and interdisciplinaryteams.

3. Professional Conduct: Our graduateswill hold paramount the health, safety,and welfare of the public, and conductthemselves in a professional and ethicalmanner at all times. Further, our alum-ni will communicate effectively to avariety of target audiences throughboth written and oral media.

4. Societal Contribution: Our graduateswill respond and adapt to the scientificand engineering needs of society bothnationally and internationally, seek outnew opportunities, and contribute tothe development of a healthy and glob-ally competitive economy.

5. Life-long Learning: Our graduates willcontinually build on their undergradu-ate foundation of science, engineering,and societal understanding, and contin-ue to develop their knowledge, skills,and contributions throughout their pro-fessional careers and private lives. Thiswill include active participation in pro-fessional societies, attending and mak-ing presentations at conferences, andparticipating in outreach activitieswithin their areas of expertise.

Program OutcomesTo prepare students to meet the aboveprogram educational objectives, a set ofprogram outcomes that describes whatstudents should know and be able to dowhen they graduate, have been adopted.We expect students to gain:

a. the ability to apply knowledge ofadvanced mathematics, science, biology, physiology, biotechnology, and engineering;

b. the ability to design and conductexperiments from living and non-livingsystems, as well as to analyze andinterpret data;

c. the ability to design a system, compo-nent, or process to meet desired needswithin realistic constraints such as eco-nomic, environmental, social, political,ethical, health and safety, manufactura-bility, and sustainability;

d. the ability to function on multidiscipli-nary teams;

e. the ability to identify, formulate, andsolve problems at the interface of engineering and biology;

f. the understanding of professional and ethical responsibility;

g. the ability to communicate effectively;

h. the broad education necessary tounderstand the impact of biomedicalengineering solutions in a global, economic, environmental, and societalcontext;

i. the recognition of the need for, and anability to engage in, life-long learning;

j. a knowledge of contemporary issues;and

k. the ability to use the techniques, skills,and modern engineering tools neces-sary for addressing the problems associated with the interactionbetween living and/or non-living materials and systems.

More details about program educationalobjectives and outcomes can be found athttp://bme.sunysb.edu/bme/ugrad/index.html#abet .

Freshman Fall Credits

First Year Seminar 101 1D.E.C. A 3AMS 151 3CHE 131 4PHY 131/133 4BME 100 3Total 18

Junior Fall Credits

BME 300 0AMS 310 3BIO 204 Lab 2Technical elective 3Technical elective 3ESE 271 4Total 15

Spring Credits

First Year Seminar 102 1ESG 111 3AMS 161 3CHE 132 4PHY 132/134 4MEC 203 2Total 17

Sophomore Fall Credits

AMS 261 4MEC 260 3BIO 202 3D.E.C. or BME 212 3AMS 210 3Total 16

Spring Credits

AMS 361 4MEC 262 3BME 304 3D.E.C. or BME 212 3D.E.C. 3Total 16

Spring Credits

BME 301 3BME 305 3Technical elective 3-4Technical elective 3-4D.E.C. 3Total 15-17

Spring Credits

BME 441 3Technical elective 3Technical elective 3Technical elective 3D.E.C. 3Total 15

Senior Fall Credits

BME 440 3Technical elective 3Technical elective 3Technical elective 3D.E.C. 3Total 15

Sample Course Sequence for the Major in Biomedical Engineering

BIOMEDICAL ENGINEERING

http://bme.sunysb.edu/bme/ugrad/index.html#abet

http://bme.sunysb.edu/bme/ugrad/index.html#abet



Courses Offered in BiomedicalEngineeringSee the Course Descriptions listing inthis Bulletin for complete information.

BME 100 Introduction to BiomedicalEngineering

BME 201-H Biomedical Engineering andSociety

BME 212 Biomedical EngineeringResearch Fundamentals

BME 213 Studies in Nanotechnology

BME 300 Writing in BiomedicalEngineering

BME 301 Bioelectricity

BME 303 Biomechanics

BME 304 Genetic Engineering

BME 305 Biofluids

BME 311 Fundamentals of Macro toMolecular Bioimaging

BME 313 Bioinstrumentation

BME 353 Biomaterials: Manufacture,Properties, and Applications

BME 381 Nanofabrication in BiomedicalApplications

BME 400 Research and Nanotechnology

BME 404 Essentials of TissueEngineering

BME 420 Computational Biomechanics

BME 430 Engineering Approaches toDrug Delivery

BME 440 Biomedical EngineeringDesign

BME 441 Senior Design Project inBiomedical Engineering

BME 461 Biosystems Analysis

BME 475 Undergraduate TeachingPracticum

BME 481 Biosensors

BME 488 Biomedical EngineeringInternship

BME 499 Research in BiomedicalEngineering

Acceptance into the Major inBiomedical EngineeringFreshman applicants who have specifiedtheir interest in the major in BiomedicalEngineering may be accepted directly intothe major upon admission to the Uni-versity. Freshman and transfer applicantsadmitted to the University but not imme-diately accepted into the BiomedicalEngineering major may apply for accep-tance to the major at any time during theacademic year by contacting the director

of the undergraduate program. Studentsin good academic standing may apply inany semester, but priority for admission to the Biomedical Engineering major isgiven to those students who have:

1. completed MAT 132 and PHY 132/134or their equivalents;

2. earned a g.p.a. of 3.20 in all mathemat-ics and physics courses with no morethan one grade in the C range; and

3. received completed course evalua-tions for all transferred courses thatare to be used to meet requirementsof the major.

Requirements for the Major inBiomedical Engineering (BME)The curriculum begins with a focus onbasic mathematics and the natural sci-ences followed by courses that empha-size engineering science and bridgingcourses that combine engineering sci-ence and design. The sequence of cours-es culminates with a one-year designexperience that integrates the science,engineering, and communication knowl-edge acquired. The technical electivesand additional courses are chosen in con-sultation with a faculty advisor, takinginto consideration the particular interestof the student.

Completion of the major requiresapproximately 130 credits.

1. Mathematicsa. AMS 151, 161 Calculus I, II

b. AMS 261 or MAT 203 or MAT 205Calculus III

c. AMS 361 or MAT 303 or MAT 305Calculus IV

d. AMS 210 Matrix Methods andModels

e. AMS 310 Survey of Probability andStatistics

Note: The following alternate calculuscourse sequences may be substitutedfor AMS 151, 161:

MAT 125, 126, 127

or MAT 131, 132

or MAT 141, 142

or MAT 171

2. Natural Sciencesa. BIO 202 Fundamentals of Biology:

Molecular and Cellular Biology orBIO 203 Fundamentals of Biology:Cellular and Organ Physiology

b. CHE 131, 132 General Chemistry I, II

c. PHY 131/133, 132/134 ClassicalPhysics I, II with labs

Note: The following alternate sciencesequences may be substituted:

PHY 125, 126, 127, or PHY 141, 142in lieu of PHY 131/133, 132/134

CHE 141, 142, in lieu of CHE 131,132

3. Computers and Programming a. ESG 111 C Programming for

Engineers or ESE 124 Computer Techniquesfor Electronic Designor CSE 130 Introduction toProgramming in C

b. MEC 203 Technical Drawing andComputer Aided Drafting

4. Engineering a. MEC 260 Engineering Statics

b. MEC 262 Engineering Dynamics

c. ESE 271 Electrical Circuit Analysis I

5. Biomedical Engineeringa. BME 100 Introduction to Biomedical

Engineering

b. BME 212 Laboratory Methods inBiomedical Engineering

c. BME 301 Bioelectricity

d. BME 304 Genetic Engineering

e. BME 305 Biofluids

f. BME 440 Biomedical EngineeringDesign

g. BME 441 Senior Design Project inBioengineering

6. Biomedical Engineering Specializationsand Technical ElectivesBiomedical engineering students mustcomplete a specialization, composed ofat least 30 credits in one of four areas,including at least two 3- to 4-creditdesign technical elective courses. (Seebelow for the four specializations withcourse options.) The specializationmust be declared in writing by the endof the sophomore year and is selectedin consultation with the faculty advi-sor to ensure a cohesive curriculumwith depth at the upper level.

7. Upper-Division Writing Requirement:BME 300 Writing in BiomedicalEngineering All degree candidates must demon-strate skill in written English at alevel acceptable for engineering


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majors. All Biomedical Engineeringstudents must complete the writingcourse BME 300 concurrently with aselected BME 300-level course. Thequality of writing in technical reportssubmitted for the course is evaluated,and students whose writing does notmeet the required standard arereferred for remedial help. Satis-factory writing warrants an S gradefor BME 300, thereby satisfying therequirement.

GradingAll courses taken to satisfy 1 through 6above must be taken for a letter grade. Agrade of C or higher is required in thefollowing courses: AMS 151, 161 orequivalent; BIO 202 or 203; CHE 131,132 or equivalent; PHY 131/133, 132/134or equivalent; all BME courses.

SpecializationsTo complete the specialization, studentschoose from the technical elective courselist for one of the four specializations.Other courses may be used towards thisrequirement with the permission of theundergraduate program director.

a. Biomechanics

Courses that focus on developing anunderstanding of mechanical struc-tures and dynamics of biological sys-tems. This specialization is appropri-ate for students interested in the areasof biofluid mechanics, hard and soft tis-sue biomechanics, biomaterials, med-ical prosthetics, or bioinstrumentation.

Recommended courses: BME 303 Biomechanics


BME 381 Nanofabrication inBiomedical Applications


BME 420 ComputationalBiomechanics

BME 430 Engineering Approachesto Drug and Gene Delivery

BME 481 Biosensors

ESG 302 Thermodynamics ofMaterials

ESM 353 Biomaterials

MEC 363 Mechanics of Solids

Alternative courses:AMS 331 Mathematical Modeling

CSE 326 Digital Image Processing

CSE 332 Introduction to ScientificVisualization

ESE 315 Control System Design

ESM 369 Polymers

ESM 450 Phase Changes andMechanical Properties of Materials

MEC 320 Engineering DesignMethodology and Optimization

MEC 402 Mechanical Vibrations

MEC 410 Design of MachineElements

MEC 411 Control System Analysisand Design

MEC 455 Applied Stress Analysis

b. BiomaterialsCourses focusing on developing anunderstanding of various material sci-ences issues pertinent to biomedicalproblems, specifically issues of bio-compatibility of materials used in thedesign of biomedical devices andimplants. Students study the basics ofbiology, organic chemistry, and mater-ial science to understand how to applyknowledge acquired to the design ofprosthetic devices and materials thatwill be in contact with living tissuesand organs.

Recommended courses:BME 303 Biomechanics


BME 381 Nanofabrication inBiomedical Applications or BME481 Biosensors


BME 420 ComputationalBiomechanics


ESG 332 Materials Science I

ESM 335 Strength of Materials

ESM 353 Biomaterials

ESM 369 Polymers

Alternative courses:ESG 281 Engineering Intro to SolidState

ESG 302 Thermodynamics ofMaterials

ESG 316 Engineering ScienceDesign II

ESM 221 Introduction to theChemistry of Solids

ESM 309 Thermodynamics of Solids

ESM 325 Diffraction Techniques andStructure of Solids

ESM 334 Materials Engineering

ESM 335 Strength of Materials

ESM 355 Materials and Processes inManufacturing Design

ESM 450 Phase Changes andMechanical Properties of Materials

MEC 310 Introduction to MachineDesign

MEC 320 Engineering DesignMethodology and Optimization

MEC 410 Design of MachineElements

MEC 455 Applied Stress Analysis

c. BioelectricityCourses focusing on the descriptionof biological cells, tissues, and organ-isms as complex systems. This spe-cialization is appropriate for studentsinterested in the areas of bioinstru-mentation, medical imaging, electri-cal prosthetics, electromagnetic com-patibility, tissue engineering, orbioinformatics.

Recommended courses:BME 313 Bioinstrumentation


BME 481 Biosensors

CHE 321 Organic Chemistry

CSE 377 Introduction to MedicalImaging

ESE 211 Electronics Laboratory A

ESE 218 Digital System Design

ESE 306 Random Signals andSystems

ESE 314 Electronics Laboratory B

ESE 315 Control System Design

ESE 372 Electronics

Alternative courses:AMS 311 Probability Theory

ESE 305 Deterministic Signals andSystems

ESE 324 Electronics Laboratory

EST 421 Starting the High-Technology Venture

d. Molecular and Cellular BiomedicalEngineering Courses focus on the application of bio-chemistry, cell biology, and molecularbiology (i.e., recombinant DNA metho-dology) to the broad fields of geneticengineering, biotechnology, bionano-technology, and biosensors. Includes




the specific engineering principles thatare applied to problems involvingstructure and function of moleculesand cells in areas such as tissue engi-neering, gene therapy, microarray,drug design and delivery, structuralbiology computational methods, andbioinformatics. Students must takeboth BIO 202 and 203, as well as CHE321 and 322.

Recommended courses:(Students should take both BIO 202and BIO 203.)

BIO 202 Fundamentals of Biology:Molecular and Cellular Biology

BIO 203 Fundamentals of Biology:Cellular and Organ Physiology

BIO 317 Principles of CellularSignaling


BME 381 Nanofabrication inBiomedical Applications



BME 481 Biosensors

CHE 321 Organic Chemistry I

CHE 322 Organic Chemistry II

CHE 327 Organic ChemistryLaboratory

Alternative courses:

BIO 302 Human Genetics

BIO 310 Cell Biology

BIO 311 Techniques in Molecularand Cellular Biology

BIO 320 General Genetics

BIO 325 Animal Development

BIO 328 Mammalian Physiology

BIO 361 Biochemistry I

BIO 362 Biochemistry II

BIO 365 Biochemistry Laboratory

BME 303 Biomechanics


CHE 312 Physical Chemistry

CHE 346 Biomolecular Structureand Reactivity

CHE 353 Chemical Thermodynamics

ESG 332 Materials Science I

BME/ESM 353 Biomaterials:Manufacture, Properties andApplications

ESM 369 Polymers


biomedical engineering biomedical engineering(bme) · . ... phy 131/133 4 bme 100 3 total 18 junior...

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