biochemistry of lipids
TRANSCRIPT
Biochemistry of LipidsBiochemistry and Molecular Biology
Fatty Acids
Fatty Acids
Fatty Acids
C1C16
e.g. oleic Acid is abbreviated as 18:1D9
e.g. palmitic Acid is abbreviated as 16:0
Fatty Acids
Lauric Acid
MW: 200solubility in H2O: 0.063 mg g-1
(solubility in benzene: 2.60 mg g-1)
Glucose
MW: 180solubility in H2O: 1,100 mg g-1
Fatty AcidsSome FAs and their common names…
14:0 myristic acid 16:0 palmitic acid 18:0 stearic acid 18:1 cis9 oleic acid18:2 cis9,12 linoleic acid18:3 cis9,12,15 -linonenic acid 20:4 cis5,8,11,14 arachidonic acid20:5 cis5,8,11,14,17 eicosapentaenoic acid
Oleic Acid
Fatty Acids
Linoleic acidLinolenic acid
Fatty Acids
e.g. Fatty Acid Melting Point (oC)
12:0 44.214:0 53.916:0 63.118:0 69.818:1 13.418:2(9,12) 1.518:3(9,12,15) - 11.0
Fatty Acids
Isomerism
C C
H
H
C C
H H
Cl
Cl Cl
Trans or E
Cis or Z
Cl
Fatty Acids
Triacylglycerides
Glycerol
alcohol carboxylic acid ester
Triacylglycerides
Triacylglycerides
Glycerol
Fatty Acid
Ester Link
Triacylglycerides
Diglyceride
Triglycerides
G
FA1
FA2
G
FA1
FA2
FA3
Triacylglycerides
Triglycerides
Triglycerides
Adipocytes
Triglycerides
Triglycerides
Energy from fat
Phospholipids
The four phosphlipids
Cholesterol
Fluid Mosaic Model
Fat in the blood
Vitamins