By: Dr. Pooja Farswan Dr. Sandeep Kumar Talwar

BIOACTIVE PEPTIDES DERIVED FROM FOOD AND IT’S

DIFFERENTAPPLICATIONS

INTRODUCTION

DEFINITION

TYPES AND SOURCES

PROPERTIES

APPLICATIONS

LAYOUT

RESULT OF PROTEOLYTIC ENZYME ACTIVITY

LIMITED HYDROLYSIS

PRODUCED HIGH QUALITY FOOD PRODUCTS

DIFFERENT SOURCES

VARIOUS PROPERTIES

INTRODUCTION

HIGHER ABSORPTION RATE HIGH BIOLOGICAL ACTIVITY AND

NUTRITIONAL VALUE ( E. ECKART,A. ZAMBROWICZ, M.POKORA et. al2012)

INTRODUCTION

THEY ARE FRAGMENTS OF PROTEINS THAT ARE NOT ACTIVE IN THE SEQUENCE OF THE PRECURSORS BUT AFTER ENZYMATIC RELEASE THEY INTERACT WITH RECEPTORS TO REGULATE THE BODY FUNCTIONS.

(Kolakowski et al.,2005)

DEFINITION

SOURCES

PLANT

WHEAT

BARLEY

ANIMAL

EGG

MILK

FISH

PORK

EGG

• OVALBUMIN

• PHOSVITIN

• OVOTRANSFERRIN

• OVALBUMIN

• LECITHIN FREE EGG YOLK

MILK

• LACTALBUMIN

• LACTOGLOBUMIN

• CASEIN

FISH

AND

PORK

• MYOFIBRILLAR PROTEIN HYDROSYLATE

ANTIOXIDANT ACTIVITY Presence of aromatic amino acids

Scavenging of free radicals

Chelation of transition metals

Reduction of hydroperioxides

Oxidants elimination

(A.Polanovaski,J.Chrzanowska, M.Szoltysik et.al2012)

PROPERTIES

ANTI – HYPERTENSIVE ACTIVITY Inhibit ACE

Mainly found in egg albumin

Well absorbed by the intestine

ANTI-TUMOUR ACTIVITY Inhibits the proliferation of Tumour cells

Increase intracellular GSH

Present mainly in egg ovomucin

ANTI- MICROBIAL ACTIVITY Mainly due to tryptophan and

arginine Bind to cell liposaccharide wall

Bactericidal activity

Anti –viral activity

METAL BINDING PROPERTY

Increase the bioavailaibility of minerals

Prevent the oxidation

Increase calcium absorption

IMMUNOSTIMULATING ACTIVITY

Immunnomodulating effect

Mostly derived from milk

PREVENT ADVERSE CHANGES IN FOOD PRODUCTS

PREVENT DISEASE CAUSED BY OXIDATIVE STRESS

MUUTIFUNCTIONAL CHARACTER

INVACTIVATION OF HERPES VIRUS

NUTRITIONAL SUPPLEMENTS

APPLICATIONS

PHARMACOLOGICAL PREPARATIONS

PREVENT OSTEOPOROSIS

DELAY THE AGING PROCESS

REDUCE THE RISK OF THROMBOTIC DISEASE

Korhonen H (2009) Milk-derived bioactive peptides: From science to applications. J Funct Foods 1, 177–187.

  Kelly D & Coutts APG (1997) Biologically active peptides in

colostrum and milk. In Digestive Physiology in Pigs, pp. 163–170 [J-P Laplace, C Fe´vrier and A Barbeau, editors Saint Malo, France: INRA.

  Meisel H (2005) Biochemical properties of peptides encrypted in

bovine milk proteins. Curr Med Chem 12, 1905–1919.

REFERENCES

Moller NP, Scholz-Ahrens KE, Roos N, et al. (2008) Bioactive peptides and proteins from foods: indication for health effects. Eur J Nutr 47, 171–182.

  Hu WL, Mazurier J, Sawatzki G, et al. (1988) Lactotransferrinreceptor of mouse small-intestinal brush border. Biochem J 249, 435–

441.  Guesdon B, Pichon L & Tome´ D (2006) Opioid Peptides. In

Nutraceutical Proteins and Peptides in Health and Disease, pp. 367–376 [Y Mine and F Schahidi, editors]. Boca Raton Florida: CRC Press.

THANK YOU