best practices for retinal detachment repair best ... · best practices for retinal detachment...

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1 Best Practices for Retinal Detachment Repair Dean Eliott Associate Director, Retina Service Massachusetts Eye & Ear Infirmary Harvard Medical School Boston, MA Best Practices for Retinal Detachment Repair Dean Eliott Associate Director, Retina Service Massachusetts Eye & Ear Infirmary Harvard Medical School Boston, MA Financial Disclosure Ad hoc consulting – Acucela – Alcon – Alimera – Allergan – Arctic Bausch & Lomb – Genentech – Thrombogenics Research funding Advanced Cell Technology Juvenile Diabetes Foundation Retinal Detachment Repair indications & complications pneumatic retinopexy scleral buckle – vitrectomy vitrectomy / buckle

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Page 1: Best Practices for Retinal Detachment Repair Best ... · Best Practices for Retinal Detachment Repair Dean Eliott Associate Director, Retina Service Massachusetts Eye & Ear Infirmary

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Best Practices for Retinal Detachment Repair

Dean EliottAssociate Director, Retina ServiceMassachusetts Eye & Ear Infirmary

Harvard Medical SchoolBoston, MA

Best Practices for Retinal Detachment Repair

Dean EliottAssociate Director, Retina ServiceMassachusetts Eye & Ear Infirmary

Harvard Medical SchoolBoston, MA

Financial Disclosure

• Ad hoc consulting

– Acucela

– Alcon

– Alimera

– Allergan

– Arctic

– Bausch & Lomb

– Genentech

– Thrombogenics

• Research funding

– Advanced Cell Technology

– Juvenile Diabetes Foundation

Retinal Detachment Repair

• indications & complications

– pneumatic retinopexy

– scleral buckle

– vitrectomy

– vitrectomy / buckle

Page 2: Best Practices for Retinal Detachment Repair Best ... · Best Practices for Retinal Detachment Repair Dean Eliott Associate Director, Retina Service Massachusetts Eye & Ear Infirmary

2

Pneumatic Retinopexy

• uncomplicated retinal

detachments

– retinal break located

superior 8 clock hours

– able to maintain specific

head posture

retinal break

detached retina

gas bubble

Pneumatic Retinopexy

• procedure

– retinopexy

• cryo

• laser

– gas injection

• 0.3cc 100%C3F8

• 1cc covers 4 clock hours

retinal break

detached retina

gas bubble

Pneumatic Retinopexy

• review of >4,000 eyes over 21-year period

– single operation success 75%

• new retinal breaks 12%

• PVR 5%

– final operation success 96%

• final anatomic and visual outcomes are not

disadvantaged by initial pneumatic retinopexy

Pneumatic Retinopexy

• factors affecting single operation success

– lens status

• phakic 71-84%

• psuedophakic 41-67%

– extent of detachment

• inverse relationship

– number of breaks

• inverse relationship

Page 3: Best Practices for Retinal Detachment Repair Best ... · Best Practices for Retinal Detachment Repair Dean Eliott Associate Director, Retina Service Massachusetts Eye & Ear Infirmary

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Pneumatic Retinopexy

• largest series by one surgeon (302 eyes)

– subgroup had 97% single operation success

• lens status - phakic

• extent of detachment - one quadrant

• number of breaks - one

• location of break - upper two-thirds

Pneumatic Retinopexy

• especially useful for

• phakic

• one quadrant detachment

• one break

• located upper 8 clock hours

– must have a PVD

Pneumatic Retinopexy

• reported success with more complex detachments

– large breaks

– multiple breaks

– posterior breaks

– inferior breaks

– giant retinal tears/dialyses

– PVR

Pneumatic Retinopexy

• reported success with more complex detachments

– large breaks

Page 4: Best Practices for Retinal Detachment Repair Best ... · Best Practices for Retinal Detachment Repair Dean Eliott Associate Director, Retina Service Massachusetts Eye & Ear Infirmary

4

Pneumatic Retinopexy

• reported success with more complex detachments

– multiple breaks

Pneumatic Retinopexy

• reported success with more complex detachments

– multiple breaks

Pneumatic Retinopexy

• reported success with more complex detachments

– inferior breaks

Pneumatic Retinopexy

• reported success with more complex detachments

– inferior breaks

Page 5: Best Practices for Retinal Detachment Repair Best ... · Best Practices for Retinal Detachment Repair Dean Eliott Associate Director, Retina Service Massachusetts Eye & Ear Infirmary

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Pneumatic Retinopexy

• reported success with more complex detachments

giant retinal tear

Pneumatic Retinopexy

• reported success with more complex detachments

giant retinal tear dialysis

Pneumatic Retinopexy

• reported success with more complex detachments

– early PVR

A - pigment clumps

Pneumatic Retinopexy

• reported success with more complex detachments

– early PVR

A - pigment clumps B - rolled edge

Page 6: Best Practices for Retinal Detachment Repair Best ... · Best Practices for Retinal Detachment Repair Dean Eliott Associate Director, Retina Service Massachusetts Eye & Ear Infirmary

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Pneumatic Retinopexy

• reported success with more complex detachments

– early PVR

A - pigment clumps

B - rolled edge

C - star fold

Pneumatic Retinopexy

• other arguments for pneumatic retinopexy

– avoids complexities and complications of scleral buckling surgery

ouch!

does anybody really use all of these?

courtesy of Karen Gehrs

Pneumatic Retinopexy

• other arguments for pneumatic retinopexy

– avoids complications of vitrectomy surgery

subretinal PFCL

retained anterior chamber PFCL

Pneumatic Retinopexy

• despite occasional reported success, bad procedure for

• large breaks

• multiple breaks

• posterior breaks

• inferior breaks

• giant retinal tears/dialyses

• early PVR

Page 7: Best Practices for Retinal Detachment Repair Best ... · Best Practices for Retinal Detachment Repair Dean Eliott Associate Director, Retina Service Massachusetts Eye & Ear Infirmary

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Pneumatic Retinopexy

• despite occasional reported success, bad procedure for

• large breaks

• multiple breaks

• posterior breaks

• inferior breaks

• giant retinal tears/dialyses

• early PVR

• avoid eyes with high risk of redetachment

• retinal detachments associated with high myopia, trauma, uveitis,

vitreous hemorrhage, choroidal detachment

Pneumatic Retinopexy

• highest single operation success

• phakic

• one quadrant detachment

• one break

• located upper 8 clock hours

Pneumatic Retinopexy

• highest single operation success

• phakic

• one quadrant detachment

• one break

• located upper 8 clock hours

– must have a PVD

Scleral Buckle• especially useful for

• phakic eyes

• absence of PVD

Page 8: Best Practices for Retinal Detachment Repair Best ... · Best Practices for Retinal Detachment Repair Dean Eliott Associate Director, Retina Service Massachusetts Eye & Ear Infirmary

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Scleral Buckle• especially useful for

• phakic eyes

• absence of PVD

• not ideal for

• very large breaks

• very bullous detachments

Scleral Buckle• especially useful for

• phakic eyes

• absence of PVD

• not ideal for

• very large breaks

• very bullous detachments

• bad procedure for

• posterior break(s)

• coexisting vitreous hemorrhage

• coexisting choroidal detachment

Scleral Buckle• especially useful for

• phakic eyes - no progression of cataract

• absence of PVD - young myopes with peripheral round holes and RD

• not ideal for

• very large breaks - fishmouthing

• very bullous detachments - difficult cryo, requires external drainage

• bad procedure for

• posterior break(s)

• coexisting vitreous hemorrhage

• coexisting choroidal detachment

Scleral Buckle• especially useful for

• phakic eyes

• absence of PVD

Retinal Dialysis

Page 9: Best Practices for Retinal Detachment Repair Best ... · Best Practices for Retinal Detachment Repair Dean Eliott Associate Director, Retina Service Massachusetts Eye & Ear Infirmary

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Scleral Buckle• especially useful for

• phakic eyes

• absence of PVD

Young Myope, Round Holes, No PVD

Scleral Buckle• especially useful for

• phakic eyes

• absence of PVD

Young Myope, Round Holes, No PVD

edge of RD

Scleral Buckle• especially useful for

• phakic eyes

• absence of PVD

Young Myope, Round Holes, No PVD

edge of RD

subretinal bands

Scleral Buckle• especially useful for

• phakic eyes

• absence of PVD

Young Myope, Round Holes, No PVD

edge of RD

subretinal bands

peripheral holes all

quadrants

Page 10: Best Practices for Retinal Detachment Repair Best ... · Best Practices for Retinal Detachment Repair Dean Eliott Associate Director, Retina Service Massachusetts Eye & Ear Infirmary

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Scleral Buckle• especially useful for

• phakic eyes

• absence of PVD

Young Myope, Round Holes, No PVD

edge of RD

subretinal bands

peripheral holes all

quadrantsfovea attached

subretinal bands

Scleral Buckle• especially useful for

• phakic eyes

• absence of PVD

Young Myope, Round Holes, No PVD

post-op year # 1 20/20

Scleral Buckle

• for almost all detachments

– #42 encircling band

• for myopes with severe

pathology

– #220 / #240 encircling

Scleral Buckle

• avoid complications

– adjust buckle to achieve appropriate height

courtesy of Karen Gehrs

Page 11: Best Practices for Retinal Detachment Repair Best ... · Best Practices for Retinal Detachment Repair Dean Eliott Associate Director, Retina Service Massachusetts Eye & Ear Infirmary

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Scleral Buckle

• avoid complications

– subconjunctival lashes

Scleral Buckle

• avoid complications

– exposed buckle

– infected buckle

• pseudallescheria boydii

Scleral Buckle• Once exposed, likely will need to be removed

• Exposed SB

• Coag neg staph 50%, atypical mycobacteria

• hypotropia

• fungus

• 220/240

• Pseudallescheria boydii

• 12 yrs prior

• 9 mos sx

• Many antibx

Scleral Buckle

• manage complications

– infected buckle

– orbital cellulitis

Page 12: Best Practices for Retinal Detachment Repair Best ... · Best Practices for Retinal Detachment Repair Dean Eliott Associate Director, Retina Service Massachusetts Eye & Ear Infirmary

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Scleral Buckle

• manage complications

Scleral Buckle

• manage complications

– Miragel buckle

Scleral Buckle

• manage complications

– Miragel buckle

• cryoprobe

• curette

• suction cannula

Scleral Buckle

• manage complications

– Miragel buckle

Page 13: Best Practices for Retinal Detachment Repair Best ... · Best Practices for Retinal Detachment Repair Dean Eliott Associate Director, Retina Service Massachusetts Eye & Ear Infirmary

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Vitrectomy

• most common procedure for RRD

– advances

• wide angle viewing

• chandelier lighting

• high speed cutter

• illuminated / articulating laser

• small gauge surgery

• valved cannulas

Vitrectomy

• wide angle viewing – non-contact

– BIOM

• 120 degrees

Vitrectomy

• wide angle viewing - contact

– AVI

• 130 degrees

– Volk

Vitrectomy

• wide angle viewing - contact

– AVI

• 130 degrees

– Volk

If view becomes compromised while using BIOM, switch

to Avi lens

Page 14: Best Practices for Retinal Detachment Repair Best ... · Best Practices for Retinal Detachment Repair Dean Eliott Associate Director, Retina Service Massachusetts Eye & Ear Infirmary

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Vitrectomy

• chandelier illumination

– 4th sclerotomy

– 23 or 25 ga cannula

– wide cone angle

– enables scleral depression

without an assistant

• vitreous cutter

• diathermy

Vitrectomy

• high speed cutter

– 5000 cuts / min

• improved surgeon

control

Vitrectomy

• illuminated / articulating laser

– 20 & 23 ga

– enables scleral depression without an assistant

Vitrectomy

• valved cannulas

– 23 & 25 ga, length 4 mm

– low friction silicone septum

23ga 25ga

Page 15: Best Practices for Retinal Detachment Repair Best ... · Best Practices for Retinal Detachment Repair Dean Eliott Associate Director, Retina Service Massachusetts Eye & Ear Infirmary

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Vitrectomy

• especially useful for

• pseudophakic eyes

• superior breaks

• very large breaks

• bullous detachments

• posterior breaks

• coexisting vitreous hemorrhage

• coexisting choroidal detachment

Vitrectomy

• especially useful for

• pseudophakic eyes

• superior breaks

• very large breaks

• bullous detachments

• posterior breaks

• coexisting vitreous hemorrhage

• coexisting choroidal detachment

Vitrectomy

• avoid retained subretinal perfluorocarbon

– incidence 11% of cases (in tertiary referral practice)

– risk factors

• large break(s)

Vitrectomy

• avoid retained subretinal perfluorocarbon

– incidence 11% of cases (in tertiary referral practice)

– risk factors

• large break(s)

Page 16: Best Practices for Retinal Detachment Repair Best ... · Best Practices for Retinal Detachment Repair Dean Eliott Associate Director, Retina Service Massachusetts Eye & Ear Infirmary

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Vitrectomy

• avoid retained subretinal perfluorocarbon

– incidence 11% of cases (in tertiary referral practice)

– risk factors

• large break(s)

• large retinectomy

– 360 degree, 40%

Vitrectomy

• avoid subretinal perfluorocarbon

– PFCL can migrate

• usually toward fovea

S/P PVR Surgery

subretinal PFCL6 months later – migration of subretinal PFCL

Subretinal PFCL

absolute scotoma over PFCL

relative scotoma at site of vacated PFCL

high stimulus low stimulus

Page 17: Best Practices for Retinal Detachment Repair Best ... · Best Practices for Retinal Detachment Repair Dean Eliott Associate Director, Retina Service Massachusetts Eye & Ear Infirmary

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Vitrectomy

• subretinal perfluorocarbon bubbles

– consider removal since subfoveal

Vitrectomy

• subretinal perfluorocarbon bubbles

– no intervention, but watch for migration

Vitrectomy

• subretinal perfluorocarbon bubble

Vitrectomy

• s/p subretinal perfluorocarbon removal

– soft tipped cannula

preop

postop

Page 18: Best Practices for Retinal Detachment Repair Best ... · Best Practices for Retinal Detachment Repair Dean Eliott Associate Director, Retina Service Massachusetts Eye & Ear Infirmary

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Vitrectomy

• Prevention of retained subretinal perfluorocarbon

– decrease turbulence

• lower infusion pressure

Vitrectomy

• Prevention of retained subretinal perfluorocarbon

– decrease turbulence

• lower infusion pressure

• 20-gauge better than 23-gauge

– 20-gauge: 2%

– 23-gauge: 10% 23ga 25ga

Vitrectomy

• Prevention of retained subretinal perfluorocarbon

– decrease turbulence

• lower infusion pressure

• 20-gauge better than 23-gauge

– 20-gauge: 2%

– 23-gauge: 10%

• valved cannulas

23ga 25ga

silicone septum

Vitrectomy

• Prevention of retained subretinal perfluorocarbon

– decrease turbulence

• lower infusion pressure

• 20-gauge better than 23-gauge

– 20-gauge: 2%

– 23-gauge: 10%

• valved cannulas

• saline rinse

Page 19: Best Practices for Retinal Detachment Repair Best ... · Best Practices for Retinal Detachment Repair Dean Eliott Associate Director, Retina Service Massachusetts Eye & Ear Infirmary

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Vitrectomy

• Prevention of retained subretinal perfluorocarbon

– saline rinse after fluid-air exchange

• 25 gauge needle, TB syringe

• 10 drops of BSS on macula

• aspirate with soft tipped cannula

Vitrectomy

• avoid complications

– attempted removal during fluid-air exchange but

view became compromised

Vitrectomy

• alternative to perfluorocarbon liquid

– drainage retinotomy

• increasing in popularity

Perfluorocarbon Liquid

• summary

– avoid retained PFCL

• saline rinse, especially in cases with large breaks / retinectomy

– remove subretinal PFCL when subfoveal or perifoveal

• PFCL causes absolute scotoma

• PFCL can migrate

– alternative

• drainage retinotomy

Page 20: Best Practices for Retinal Detachment Repair Best ... · Best Practices for Retinal Detachment Repair Dean Eliott Associate Director, Retina Service Massachusetts Eye & Ear Infirmary

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Vitrectomy

• avoid complications

– aim for oil at pupil plane

– avoid oil in anterior chamber

– do not overfill !!!

Vitrectomy

• watch for silicone oil emulsification

Vitrectomy

• caution if silicone IOL

– emulsification: inverse hypopyon

Vitrectomy

• caution if silicone IOL

– same patient, after oil removal

Page 21: Best Practices for Retinal Detachment Repair Best ... · Best Practices for Retinal Detachment Repair Dean Eliott Associate Director, Retina Service Massachusetts Eye & Ear Infirmary

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Vitrectomy• possible new way to remove oil from IOL

– polydimethylsiloxane

• hydrophobic

– in vitro experiment

Vitrectomy• possible new way to remove oil from IOL

– polydimethylsiloxane

• hydrophobic

– ex vivo

Vitrectomy• possible new way to remove oil from IOL

– polydimethylsiloxane

• hydrophobic

– ex vivo

Vitrectomy

• avoid complications

– suture the sclerotomies

• sunconjunctival oil droplets

Page 22: Best Practices for Retinal Detachment Repair Best ... · Best Practices for Retinal Detachment Repair Dean Eliott Associate Director, Retina Service Massachusetts Eye & Ear Infirmary

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Vitrectomy

• avoid oil leakage from sclerotomies

– granulomatous reaction to subconjunctival oil

20x 400x

Vitrectomy / Buckle

• especially useful for

• inferior breaks

• eyes at high risk for PVR

– post-trauma (especially open globe injuries)

– uveitis

– high myopia

– large breaks (giant retinal tears)

– multiple breaks

– vitreous/subretinal hemorrhage

– choroidal detachment

– early PVR (pigment clumps, rolled edges)

Redetachment due to PVR after Open Globe Injury

• Risk factors:

– Vitrectomy-buckle protected from RD-PVR compared with vitrectomy alone

(adjusted HR: 0.58, p=0.04)

Time to Redetachment due to PVR by Risk Factor

• Time to detachment by buckle status

Page 23: Best Practices for Retinal Detachment Repair Best ... · Best Practices for Retinal Detachment Repair Dean Eliott Associate Director, Retina Service Massachusetts Eye & Ear Infirmary

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Vitrectomy / Buckle

• avoid complications

– retinal fold

Retinal Detachment Repair

• pneumatic retinopexy

– phakic, one quadrant, one break, superior break, PVD

• scleral buckle

– phakic, absence of PVD (dialysis, myope with holes)

– can also be used for most detachments

• vitrectomy

– pseudophakic, superior breaks, large breaks, multiple breaks,

posterior breaks, bullous, hemorrhage, choroidal detachment

• vitrectomy / buckle

– inferior breaks, eyes at high risk for PVR (trauma, etc.)