1. In a patient with gross renal dysfunction,daily dose of some drugs needs to be considerably reduce such as:(A) Chloramphinicol(B) Gentamicin(C) Doxycycline(D) Erthromycin(E) Isoniazid2. A 30 years man present with hypertension, hematuria, palpable renal mass and flank pain.He states that a kidney disease runs in his family.laboratory abnormalties confirms renal failure.which of following is associated with the disorder described here?(A) Autosomal recessive inheritance.(B) Berry aneurysm of circle of willis.(C) Clinical manifestation most common at birth.(D) Multiple small medullary cysts in both kidneys.(E) Presence of uric acid stones.3.Which of following may cause erectile dysfunction?(A) Frusamide(B) Nitroglyceride (C) Digoxin(D) Hydrochlorothiazide(E) Propanolol4. Regarding acute tubular necrosis what is most significant?(A) Hyperkalemia(B) Initialy a concentrated urine(C) Malgnant hypertension(D) Protienuria(E) Urea is high and creatinine is normal5. Haematuria occrs in:(A) Acute glumerulonephritis(B) Polycystic ovaries(C) Nephrotic Syndrome(D) Valvular heart diseases(E) SLE6. Regarding renal artery stenosis is less likely if:(A) Hypertension is sever or recent onsent,ordificlult to control.(B) Kidneys are asymmetrical in size(C) Flash pulmonary oedema occurs repeatly(D) There is peripheral vascular disease of upper limbs(E) Renal function has deteriorated on ACE inhibitors7. Cause of renal papillary necrosis include:(A) Diabetes insipidus(B) Hypertension(C) Paracetamol poisoning(D) SLE(E) Renal tubular acidosis

8. The causes nephrotic syndrome include:(A) Hepatits D(B) Minimal change glomerulonephritis(C) Treatment with silver salts(D) Renal artery occlusion(E) Lymphoma9.The anemia of chronic renal failure:(A) Responds to treatment with natural erythropoitin(B) Is partly due to longer red cell survival(C) Improve rapidly after successful renal trasplantation(D) Usually respons to vitamin B supplementations(E) Is usually of microcytic and hypochromic10.Membranous glomerulonephritis is a recognized complication of:(A) Renal amyloidosis(B) Renal carcinoma (C) Lymphoma(D) Malaria and hepatitis B infection(E) Polyarteritis nodosa11. The typical feature of analgesic nephropathy include:(A) Renal disease exclusively attributable to aspirin(B) Acute papillary necrosis with recurrent renal colic(C) Tubular atrophy and fibrosis due to renal medullary ischemia (D) Micrscopic haematuria and sterile pyuria(E) Oliguria associated with urinary tract infection12. A 55 years old woman known diabetic comes to OPD with H/O burning micturation,inc:frequency and discomfort.Urine analysis show 10.16 wbc/hpf. Urine culture yield growth of pseudomonas aeruginosa.Which of following most appropriate antibiotic to be prescribed to this lady?(A) Ampicillin(B) Ceftriaxone(C) Ciprofloxacin(D) Co-trimoxazole(E) Gentamycin13.A patient of chronic renal failure needs renal transplantation.For this reason HLA matching is required.Which of following is best site of sample for HLA matching? (A)Buccal smear(B) Renal tissue(C) WBC(d) Blood(E) Bone Marrow

14. A patient with increase urinary osmolarity while blood osmolarity is decreased.Which of following is responsible for this change?(A) Dehydration(B) SIADH(C) Diabetes incipidus(D) Diabetes mellitis(E) Renal failure15. A 30 years old man has past history of sore throat.Now complains of hematuria & fever.His blood pressure is 150/95mmHg.which of following most likely diagnosis?(A) Minimal change glomerulonephritis(B) Post-streptococcal glomerulonephritis (C) Nephritic syndrome(D) Inerstitial nephritis(E) Analgesic nephropathy16. In the investigations of renal disease :(A) A random urinary PH of 04 suggest renal tubular acidosis ( RTA)(B) Creatinine clearance is calculated from ratio of urinary and plasma concentrations(C) Urinary albumin/creatinine ratio of 1mg/mmol indicates glomerular disease (D) A Urinary protein/creatinine ratio of 50mg/mmol indicates glomerular disease(E) Renal biopsy is mandatory in chronic renal failure 17.Typical features of lower urinary tract infection ( UTIs) include(A) Rigors,loin pain& renal impairment(B) Epigastric pain anuria & hematuria(C) Progress to acute pylonephritis if untreated(D) Midstream urine culture producing Escherichia coli > 100000/ml(E) The drug of choice for the majority is Ciprofloxacin

18. In the treatment of renal calculi?(A) Anuria indicates the need for urgent for surgical intervention(B) The urine should be alkalinsed if the stone is radio-opaque(C) Bendrofluazide increases urinary calcium excretion(D) Allopurinol increases urinary urate excretion in gouty patient(E) Renal pelvic stones require removal at open surgery

19.Typical feature of prostatic carcinoma include:(A) Rapid progressive distructive uropathy(B) Presentation with renal failure always(C) Preservation of normal anatomy on digital rectal examination(D) Local spread along the lumbosacral nerve plexus and may involve ureter.(E) Osteolytic rather then osteosclerotic bone metastasis