australian patent issued to creagri® for ultraviolet radiation (uvr) protection by its...

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Australian Patent Issued to CreAgri® for Ultraviolet Radiation (UVR) Protection by its Hydroxytyrosol-Based Formulations HAYWARD, Calif., Aug. 26 /PRNewswire/ -- CreAgri, Inc.® announced today that the company has received a Patent by the Australian Patent Office, Patent Number 2003249719, which covers the protective effects provided by Hydroxytyrosol against skin damage caused by UV exposure. The patent claims are very broad and include formulations containing the two most important olive polyphenols, Hydroxytyrosol and Oleuropein, whether delivered orally and/or in conjunction with topical applications. "We believe that products containing Hydroxytyrosol, whether orally ingested and/or topically applied, will provide an effective protection against the edema and erythema produced by excessive sun exposure, especially in areas of the world where skin problems are aggravated by the depletion of the ozone layer like Australia," declares Dr. Roberto Crea, CreAgri's President and CEO and author of the patent. "Increased exposure to UV rays in humans and animals has been linked to many severe diseases, including melanoma, carcinoma and immune diseases," adds Dr. Crea. "The scientifically proven activities of Hydroxytyrosol in decreasing levels of TNF- alpha and in scavenging free radical molecules may partially explain the protective effect on skin," adds Dr. Cathy Bitler, CreAgri CSO and first author of a peer-reviewed publication that describes the anti-inflammatory properties of HT. Together with its immune-balancing activity, Hydroxytyrosol, provided in high concentration by CreAgri's proprietary formulation, Hidrox®, directly blocks the effects of UV-induced free radicals in skin and other tissues of the body, and thereby, decreasing the concomitant inflammation. Hidrox® provides the highest amount of Hydroxytyrosol in its natural environment, as in the juice of olives. Hidrox® is the only Hydroxytyrosolrich formulation in the world produced from organic olives that does not involve extraction by solvents or other chemical separations. The product is certified Generally Recognized as Safe (GRAS) and has been successfully tested in several human trials in many countries of the world, including USA, Japan and Malaysia.

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Australian Patent Issued to CreAgri®

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  • Australian Patent Issued to CreAgri for

    Ultraviolet Radiation (UVR) Protection

    by its Hydroxytyrosol-Based

    Formulations

    HAYWARD, Calif., Aug. 26 /PRNewswire/ -- CreAgri, Inc. announced today that the

    company has received a Patent by the Australian Patent Office, Patent Number

    2003249719, which covers the protective effects provided by Hydroxytyrosol against

    skin damage caused by UV exposure.

    The patent claims are very broad and include formulations containing the two most

    important olive polyphenols, Hydroxytyrosol and Oleuropein, whether delivered orally

    and/or in conjunction with topical applications.

    "We believe that products containing Hydroxytyrosol, whether orally ingested and/or

    topically applied, will provide an effective protection against the edema and erythema

    produced by excessive sun exposure, especially in areas of the world where skin

    problems are aggravated by the depletion of the ozone layer like Australia," declares Dr.

    Roberto Crea, CreAgri's President and CEO and author of the patent. "Increased

    exposure to UV rays in humans and animals has been linked to many severe diseases,

    including melanoma, carcinoma and immune diseases," adds Dr. Crea.

    "The scientifically proven activities of Hydroxytyrosol in decreasing levels of TNF-

    alpha and in scavenging free radical molecules may partially explain the protective

    effect on skin," adds Dr. Cathy Bitler, CreAgri CSO and first author of a peer-reviewed

    publication that describes the anti-inflammatory properties of HT.

    Together with its immune-balancing activity, Hydroxytyrosol, provided in high

    concentration by CreAgri's proprietary formulation, Hidrox, directly blocks the effects

    of UV-induced free radicals in skin and other tissues of the body, and thereby,

    decreasing the concomitant inflammation.

    Hidrox provides the highest amount of Hydroxytyrosol in its natural environment, as

    in the juice of olives. Hidrox is the only Hydroxytyrosolrich formulation in the world produced from organic olives that does not involve extraction by solvents or other

    chemical separations.

    The product is certified Generally Recognized as Safe (GRAS) and has been

    successfully tested in several human trials in many countries of the world, including

    USA, Japan and Malaysia.

  • About CreAgri (www.creagri.com)

    CreAgri is the world's leading developer and supplier of antioxidant olive polyphenols

    for functional foods and beverages, dietary supplements, cosmetics and skincare

    applications. For ten years, CreAgri has been the research leader in providing

    consumers and industry with the highest quality free radical-scavenging olive

    polyphenols. CreAgri's' internationally acclaimed product, HIDROX, has been

    formulated for dietary supplements, cosmetics, and skin-care products; all featuring the

    antioxidant power of natural HYDROXYTYROSOL, the olive active bio-phenol with

    the highest free-radical scavenging activity of any known natural or synthetic

    antioxidants.

    About HIDROX

    HIDROX is CreAgri's trademarked hydroxytyrosol formulation, a powerful

    polyphenol scientifically recognized for its anti-oxidant properties and efficacy in heart

    and joint health. HIDROX is the only olive polyphenols formulation with GRAS

    certification, meaning that it has been subjected to the most comprehensive set of safety

    and clinical efficacy tests. HIDROX is also covered by the largest number of

    international patents for applications that include hydroxytyrosol and olive polyphenols.

    It is available in three forms to fulfill a variety of applications: HIDROX 12% Total

    Polyphenols (6% hydroxytyrosol) freeze dried powder, HIDROX 6% Total

    Polyphenols (3% hydroxytyrosol) powder and HIDROX0.5% Total Polyphenols

    liquid. All products are available in volumes ranging from kilograms to metric tons and

    can be ordered directly from CreAgri.

    About Skin Cancer

    Each year more than 1,200 Australians die from skin cancer and in the US, more than 1

    million new cases of skin cancer are diagnosed each year. (1) The American Cancer

    Society estimates that there are currently 480,000 cases of melanoma in the US alone

    today and that there are 7,700 deaths per year from the disease. Melanoma incidence

    rates in Australia and New Zealand are around four times as high as those found in

    Canada, the US and the UK. (2) Overall, melanoma is the fourth most common cancer

    in Australia. (3)

    For more information about CreAgri, visit www.creagri.com. For media related

    inquiries, contact Paolo Pontoniere (510) 732-6478 ext. 107, [email protected]

    or Gillian Christie at Christie Communications,www.christiecomm.com (805) 969-3744

    or [email protected].

    (1) theozonehole.com, American Cancer Society's 2007 Facts & Figures

    (2) Australian Institute of Health and Welfare and Australasian Association of Cancer

    Registries. Cancer in Australia 2001. 2004.

  • (3) Australian Institute of Health and Welfare (AIHW) & Australasian Association of

    Cancer Registries (AACR). Cancer in Australia: an overview, 2006. Cancer Series

    Number 37. Canberra: AIHW, 2007.

    SOURCE CreAgri, Inc.