assessment of neurologic function_2012
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ASSESSMENT OF
NEUROLOGIC FUNCTION
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LEARNING OBJECTIVES
1. Describe the structure and functions of the central andperipheral nervous systems
2. Differentiate between pathologic changes that affect motorcontrol and those that affect sensory pathways.
3. Compare the functions of the sympathetic and parasympatheticnervous systems
4. Describe the significance of physical assessment to thediagnosis of neurologic dysfunction.
5. Describe changes in neurologic function associated with agingand their impact on neurologic assessment findings.
6. Describe diagnostic tests used for assessment of suspectedneurologic disorders and the related nursing implications.
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GLOSSARY
Agnosia loss of ability to recognize objects through aparticular sensory may be visual, auditory, tactile
Ataxia Inability to coordinate muscle movements,resulting in difficulty in walking, talking, and performing
self-care activities. Autonomic Nervous system division of the nervous
system that regulates the involuntary body functions
Axon portion of the neuron that conducts impulses
away from the cell body. Babinski reflex (sign) a reflex action of the toes,indicative of abnormalities in the motor control pathwaysleading from the cerebral cortex.
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Clonus abnormal movement marked by alternating contraction andrelaxation of a muscle occurring succession.
Delirium transient loss of intellectual function, usually due tosystemic problems.
Dendrite portion of the neuron that conducts impulses toward the
cell body. Flaccidity displaying lack of muscle tone; limp, floppy
Parasympathetic Nervous system division of the autonomicnervous system active primarily during non-stressful conditions,controlling mostly visceral functions.
Photophobia- inability to tolerate light
Position (postural) sense awareness of position of parts of thebody without looking at them; also referred to as proprioception.
Reflex an automatic response to stimuli
Rigidity increase in muscle tone at rest characterized by increasedresistance to passive stretch
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Romberg Test test for cerebellar dysfunction requiringthe patient to stand with feet together, eyes closed andarms extended; inability to maintain the position, witheither significant stagger or sway, is a positive test.
Spasticity sustained increase in tension of a musclewhen it is passively lengthened or stretch.
Sympathetic nervous system division of the autonomicnervous system with predominantly excitatory response;the fight-or-flight system
Vertigo an illusion of movement, usually rotation
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Anatomic and Physiologic
Overview
Nervous system
2 major parts:
a. Nervous systemb. Peripheral nervous system
Function: control motor, sensory, autonomic,cognitive, behavioral activities.
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The brain itself contains more than 100
billion cells that link the motor and sensory
pathways, monitor the bodys processes,
respond to the internal and externalenvironment, maintain homeostasis, and
direct all psychological, biologic and
physical activity through complex chemicaland electrical messages.
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CELLS OF THE NERVOUS
SYSTEM
Neuron- functional unit of the brain
Composed of dendrites, a cell body and axon.
Dendrites are branch-type structures for
receiving electrochemical messages.
Axon is a long projection that carries electrical
impulses away from the cell body.
*some neurons have a myelinated sheath thatincreases the speed of conduction*
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NEUROTRANSMITTERS
Communicate messages from one neuron
to another or from a neuron to a specific
target tissue.
*stored in synaptic vesicles*
As an electrical action potential propagated
along the axon reaches the nerve terminal,
it is released into the synapse.
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Diffuses or is transported across the
synapse, binding to receptors in the
postsynaptic cell membrane.
It potentiates, terminates, or modulates a
specific action, can either excite or inhibit
activity of the target cell.
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MAJOR NEUROTRANSMITTERSNEUROTRANSMITTER SOURCE ACTION
1. Acetylcholine (major
transmitter of the PNS)
Many areas of the brain, ANS Usually excitatory; PNS effects
sometimes inhibitory (stimulation
of heart by vagal nerve)
2. Serotonin Brain stem, hypothalamus, dorsal
horn of the spinal cord
Inhibitory, helps control mood
and sleep, inhibits pain pathways
3. Dopamine Substantia nigra and basalganglia Usually inhibits, affects behavior( attention, emotions) and fine
movement
4.Norepinephrine (major
transmitter of the SNS)
Brain stem, hypothalamus,
postganglionic neurons of the
SNS
Usually excitatory; affects mood
and overall activity
5. Gamma-aminobutyric acid
(GABA)
Spinal cord, cerebellum, basal
ganglia, some cortical areas
Inhibitory
6. Enkephalin, Endorphin Nerve terminals in the spine,
brain stem, thalamus and
hypothalamus, pituitary gland
Excitatory; pleasurable
sensation, inhibits pain
transmission.
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Neurologic disorder due to an imbalance
in neurotransmitter
Ex. Parkinsons disease develops from
decreased of dopamine
Myasthenia Gravis Acetylcholine binding
in muscle cells is impaired
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Evaluating diagnostic tests detect abnormal
levels of neurotransmitter
POSITRON EMISSION TOMOGRAPHY (PET)
can detect dopamine, serotonin, andacetylcholine.
SINGLE PHOTON EMISSION COMPUTED
TOMOGRAPHY (SPECT) can detect
changes in some neurotransmitter such as
dopamine in Parkinsons disease
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CENTRAL NERVOUS
SYSTEM
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THE BRAIN
Accounts approx. 2% of the total bodyweight (average young adult)
Weighs approx: 1400 g (average adult)
1200 g (elderly persons)Divided into three major areas:
1. Cerebrum
2. Brain stem3. Cerebellum
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Cerebrum
Composed of two hemispheres:
thalamus;hypothalamus and the basal
ganglia
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Brain stem
Includes the midbrain, pons and medulla
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Cerebellum
Located under the cerebrum and behind
the brain stem
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CEREBRUM
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Gyri the outside surface of thehemispheres which has wrinkledappearance as a result of many folded
layers or convolutions. Sulcus or Fissures which serves as an
anatomic division.
Great longitudinal fissures separates thecerebrum into the right and lefthemispheres
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Corpus Callosum joined two
hemispheres at the lower portion of the
fissures.
Cerebral Cortex the external or outer
portion of the hemispheres which is made
up of gray matter approx 2 to 5 mm in
depth. Contains billions of neuron cellbodies giving it a gray appearance.
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White matter makes up the innermost
layer and is composed of myelinated
nerve fibers and neuroglia cells that form
tracts or pathways connecting variousparts of the brain with one another.
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CEREBRAL HEMISPHERES
(divided into pairs of lobes)
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FRONTAL
Largest lobe
Located in front of the brain
Major functions:
Concentration, abstract thought, information
storage or memory and motor function.
Contains brocas area left hemisphere and is
critical for motor control of speech. Responsible for a persons affect, judgment,
personality, and inhibitions.
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PARIETAL
Predominantly sensory lobe
Posterior to the frontal lobe
Analyzes sensory information Relays the interpretation of this
information to other cortical areas
Essential to a persons awareness of bodyposition in space, size and shape
discrimination, and right-left orientation
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TEMPORAL
Located inferior to the frontal and parietal
Contains auditory receptive areas
Plays a role in memory of sound andunderstanding of language and music
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OCCIPITAL
Located posterior to the parietal lobe
Responsible for visual interpretation and
memory
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Corpus Callosum
Connects the two hemispheres of the
brain
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