asaio 56th annual conference...

Providing Healthcare Solutions Through Discovery, Education & Engineering

PROGRAMASAIO 56TH ANNUAL CONFERENCEMAY 27 - 29, 2010BALTIMORE, MARYLAND

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SAVE THE DATE!ASAIO 57TH ANNUAL CONFERENCE

WASHINGTON DCJUNE 10-12 2011

PROGRAM INDEX

ASAIO MISSION STATEMENTTo Advance the Research, Development and Medical Application of Bionic Technologies

ASAIO EDUCATIONALGRANT SPONSORS

PLATINUM LEVEL

BRONZE LEVEL

ADDITIONAL SPONSORS

ASAIO MEMBER BUSINESS MEETING – PG 27

ASAIO Y NOSÉ INTERNATIONAL FELLOWSHIP – PG 14

BARNEY CLARK AWARD PRESENTATION – PG 22

BOARD OF TRUSTEES 5/31/2009 – 5/29/2010 – PG 4

EXHIBITS – PGS 8 – 10

FELLOWSHIPS & AWARDS – PGS 14 & 22

FLOOR PLAN HILTON BALTIMORE – PG 7

HASTINGS LECTURE – PG 22

INTENSIVE DIALYSIS DAY PROGRAM – PG 20 – 21

NEW VENTURE FORUM – PG 27

PROGRAM COMMITTEE – PG 5

PROGRAM OUTLINE – PGS 11 – 12

REGISTRATION ASAIO – PG 8

WELCOME RECEPTION – PG 19

** Denotes an ASAIO Member

W WW.ASAIO.COMHOME

ABOUT US

MEMBERSHIP

FELLOWSHIPS

FOR YOUNG INNOVATORS ASAIOfyi

FORMS

ANNUAL CONFERENCE

EXHIBITS & INDUSTRY

JOURNAL

ABSTRACTS

CAREER CONNECTION

CALENDAR OF EVENTS

DATES & DEADLINES

COMMITTEES

LINKS

INDUSTRY & SCIENTISTS

PROJECT BIONICS

ARTIFICIAL ORGAN EDUCATION

GOVERNMENT & FUNDING

RESEARCH REPORTS

SPONSORSHIP OPPORTUNITIES

PHOTO GALLERY

MEMBERS AREA

ASAIO INC7700 Congress Avenue, Suite 3107Boca Raton, Florida 33487-1356Tel 561.999.8969 • Fax [email protected] • www.asaio.com

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ASAIO BOARD OF TRUSTEESMAY 31, 2009 THROUGH MAY 29, 2010

William Holman, MDPresident

H David Humes, MDSecretary/Treasurer

Kurt Dasse, PhDProgram Chairman

Mark Slaughter, MDDeputy Program Chairman

Wayne Richenbacher, MDImmediate Past President

Gerson Rosenberg, PhDInvestment Director

Past President

Stephen Ash, MDPast President

Brian Duncan, MD, MBA Peter Wearden, MD, PhD William Weiss, MD

Andre Kaplan, MD Conrad Zapanta, PhD Karen May-Newman, PhD

The Above Individuals Constitute the ASAIO Executive Committee

Steven Koenig, PhD

William Wagner, PhDPresident-Elect

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ASAIO PROGRAM COMMITTEE BALTIMORE 2010

Kurt Dasse, PhDProgram Chairman

Mark Slaughter, MDDeputy Program

Chairman

Ranjit John, MD

Cardiac Track Chairman

Steven KoenigBionegineering Track Chairman

William Fissell, MDRenal Track Chairman

Edwin McGee, MDBrian Duncan, MD, MBATrevor Snyder, PhDKeith Cook, PhD

Zhongjun Wu, PhDNicholas Hatsopoulos, PhDThomas Meese, BSE

Roberta Bogaev, MDEgemen Tuzun, MDRichard Aghababian, MD

Timothy Baldwin, PhDSonna Patel-Raman, PhDTracy Warren

Program Committee Members

Program ChairmanKurt Dasse, PhD

Deputy Program ChairmanMark Slaughter, MD

Cardiac Track ChairmanRanjit John, MD

Bioengineering Track ChairmanSteven Koenig, PhD

Renal Track ChairmanWilliam Fissell, MD

CardiopulmonaryKeith Cook, PhDAly El-Banayosy, MDEdwin McGee, MDJeffrey Morgan, MD

BioengineeringTrevor Snyder, PhDKartik Sundareswaran, PhDAmy Throckmorton, PhD

RenalRobert Lindsay, MDAndre Kaplan, MD

ABSTRACT REVIEWERS 2010 FELLOWSHIPS & AWARDSASAIO YOUNG INNOVATOR FELLOWSHIPSFIRST TIME AUTHORS

Sponsored by an Educational Grant from Lippincott Williams and Wilkins

Mickey Ising, BS – University of Louisville“Delivering Physiologic Pulse Pressures with ContinuousFlow Ventricular Assist Devices”

Yajuan Wang, MS – Carnegie Mellon University“Optimal Identification of Need for Right VentricularSupport Using Cost-Sensitive Decision Tree”

ASAIO FELLOWSHIP RECIPIENTSSponsored by an Educational Grant from Levitronix

Rebecca Schewe, MS – University of Michigan“Compliant Thoracic Artificial Lung Design Using Fluid-Structure Interaction Modeling”

Jason Nanna, BS – Penn State University“An Improved Experimental Wall Shear Estimation within a50cc Penn State Blood Pump”

Jaewook Nam, PhD – Rice University“Modeling and Numerical Analysis of Platelet Activation,Adhesion and Aggregation in Artificial Organs”

Pere Ventura, BS – Intermountain Medical Center“Outcomes with the Levitronix CentriMag asCardiopulmonary Support (CPS) for Cardiogenic Shock”

Sonya Bhavsar, BS – Virginia Commonwealth University“Use of External Pressure Application to Augment Fontan Hemodynamics”

Alexandre Peyser, BS – Columbia University“Dialyzer End-Caps Revisited”

Editor Joseph B. Zwischenberger, MDJohnston-Wright Professor and Chairman of SurgeryChandler Medical CenterUniversity of KentuckyLexington, Kentucky 40536Tel: 859.323.6013Email: [email protected]

Marjory SpraycarManaging Editor, ASAIO JournalTel: 410.321.5031Fax: 410.321.1456 Email: [email protected]

ASAIO JOURNAL

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FELLOWSHIPS & AWARDS Continued

ASAIO Y NOSÉ INTERNATIONAL FELLOWSHIP

Takashi Nishimura, MD, PhD – Univ of Tokyo“Development of Native Heart Load Control System withContinuous Flow Ventricular Assist Device for Bridge to Recovery of Failing Heart”

SPONSORED BY THE Y NOSÉ FELLOWSHIP FUND

ASAIO WILLEM J. KOLFF / DON B. OLSEN AWARD

Nobumasa Katagiri, ME – Nat’l CV Ctr Research Inst“An Ultra-Durable Heparin-Free Pediatric and Adult ECMO Systems and Its Clinical Application in Japan”

SPONSORED BY THE MEDFORTE FOUNDATION

BARNEY CLARK AWARD

Eli Friedman, MDDownstate Medical Center

Eli Friedman, born inBrooklyn, obtained a BSdegree from BrooklynCollege and his MD Fromthe State University ofNew York, DownstateMedical Center. HisNephrology fellowshipwas at the Peter BentBrigham Hospital withJohn Merrill. He returnedto Downstate in 1963 asan assistant professorand established a nephrology program and one of the firstdialysis units outside Seattle. He became Professor ofMedicine in 1971 and in 1992 was appointed DistinguishedTeaching Professor.

Eli is a distinguished teacher, researcher, speaker andauthor on kidney failure and many other aspects ofnephrology and is renowned around the world. He waspresident of the ASAIO in 1987-88 and Editor of the ASAIOJournal from 1968 to 2003. He is a past president of theISAO and of the International Society for GeriatricNephrology and Urology and has received many prestigioushonors and awards. He has always been an advocate forpatients and set up the first patient organization in theUnited States, now called the American Association ofKidney Patients.

ACCREDITATION CME/CCP/CNECME 19.5 AMA PRA CATEGORY 1 CREDITS™ - PHYSICIANSThis activity has been planned and implemented inaccordance with the essential areas and policies of theAccreditation Council for Continuing Medical Education(ACCME) through the joint sponsorship of the University ofMassachusetts Medical School Office of Continuing MedicalEducation (UMMS-OCME) and ASAIO. The UMMS-OCME isaccredited by the ACCME to provide continuing medicaleducation for physicians.

The University of Massachusetts Medical School designatesthis educational activity for a maximum of 19.5 AMA PRACategory 1 Credits™. Physicians should only claim creditcommensurate with the extent of their participation in the activity.

Accreditation for the ASAIO Program

THURSDAY, MAY 27 7.5 Contact Hours

FRIDAY, MAY 28 7.5 Contact Hours

SATURDAY, MAY 29 4.5 Contact Hours

Accreditation for the Intensive Dialysis Day Program

FRIDAY, MAY 28 16 Contact Hours

CEU 23.4 CREDIT HOURS - NURSES

Accreditation for the ASAIO Program




Accreditation for the Intensive Dialysis Day Program


CCP 23.1 CATEGORY 1 CEU’S - PERFUSIONISTThe American Board of Cardiovascular Perfusion will allotthe following Category 1 CEU's to those Perfusionist whoattend the ASAIO Annual Conference as follows:

WEDNESDAY, MAY 26 2.4 Contact Hours




Perfusionists must sign in once a day at the ASAIORegistration Desk to verify attendance.

A photo ID is required for participation to obtainregistration materials.

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EXHIBIT PRODUCT DESCRIPTIONS

CINCINNATI SUB-ZEROBOOTH 303CINCINNATI, OHIO

Cincinnati Sub-Zero has beendelivering patient temperaturemanagement systems to healthcareprofessionals since 1963; we designwith the patient in mind. Ourcomplete line of products includetherapeutic heating and coolingtherapy units along with a completeline of warming and cooling blanketsfor body temperature regulation andhyper-hypothermia treatment.

ELSEVIERBOOTH 304Elsevier is one of the world’s leadingpublisher of medical books, periodicalsand electronic reference products inthe world.

HEARTWARE, INCBOOTH 103FRAMINGHAM, MASSACHUSETTS

HeartWare, Inc. is developing a familyof implantable mechanical circulatorysupport systems for the treatment ofadvanced heart failure. Through acadence of progressively smallerdevices implanted using less invasivetechniques, HeartWare expects totreat an increasing proportion of heartfailure patients and to access them atan earlier stage of their diseaseprogression. HeartWare’s lead device,the HeartWare® Ventricular AssistSystem, incorporates state-of-the-artperipherals and features the only full-output pump designed to beimplanted less invasively in thepericardial space. The HeartWare®System has CE-Mark approval and iscurrently the subject of a 150-patientUS IDE clinical trial.

INTERNATIONAL CENTER FORARTIFICIAL ORGANS ANDTRANSPLANTATIONBOOTH 204PAINESVILLE, OHIO

The International Center for ArtificialOrgans and Transplantation isorganized to maintain and operate aneducational center. It supports theInternational Center for MedicalTechnologies’ Museum on artificialorgan technologies, manages thepublication of Artificial Organs andTherapeutic Apheresis and Dialysis, anddisseminates information on thehistorical development, current stateof the art and future development ofartificial organs and organtransplantation.

JARVIK HEART INCBOOTH 301NEW YORK, NEW YORK

Jarvik Heart, Inc is a privately held,New York based company thatdevelops and manufacturesminiaturized heart assist devices forthe treatment of severe heart failure.The Jarvik 2000 is a battery-poweredaxial-flow left ventricular assist device(LVAD). It is the smallest implantableblood pump available for the long-term treatment of Heart Failure.

LEVITRONIXBOOTH 302WALTHAM, MASSACHUSETTS

Levitronix designed, developed, andproduces the CentriMag, PediMag andPediVAS circulatory support devices.In the United States, the CentriMagpump is approved for up to 30 days ofuse for patients requiring rightventricular support, and is undergoingclinical trials to treat patients incardiogenic shock as a bridge todecision. The PediVAS is optimized toprovide circulatory support forneonatal and pediatric patients, and iscurrently only available outside theUnited States. The PediMag pump isavailable in the United States for usein a cardiopulmonary circuit for up to6 hours. CentriMag and PediVASsystems are both CE Mark approved foruse for up to 30 days for use as a VADor for ECMO.

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EXHIBIT PRODUCT DESCRIPTIONS Continued

LIPPINCOTT WILLIAMS & WILKINS – WOLTERS KLUWER HEALTHBOOTH 203PHILADELPHIA, PENNSYLVANIA

Lippincott Williams & Wilkins, aWolters Kluwer Health company is aleading international publisher ofmedical books, journals, andelectronic media. We proudly offerspecialized publications and softwarefor physicians, nurses, students andclinicians. Please visit our booth tobrowse our comprehensive product line.

MINNTECH TTGBOOTH 201MINNEAPOLIS, MINNESOTA

Minntech Corp, a Cantel Medical Corpcompany, was founded in 1974 inMinneapolis. Minntech Corp is a leaderin developing, manufacturing, andmarketing medical devices,electronics, sterilants, and waterpurification products. Some of themedical applications currently beingsupplied to partner companies arehemofiltration, hemoconcentration,immunomodulator removal,encapsulated cell technology,biopharmaceutical research, andbioartificial organs. The TherapeuticTechnologies Group within MinntechCorp is ready to provide regulatoryand marketing support to partnercompanies, as well as to provideassistance in:

• Research and development

• Product design

• Packaging

• Product validation

SYNCARDIA SYSTEMS INCBOOTH 102TUCSON, ARIZONA

The SynCardia temporary Total ArtificialHeart (TAH-t) is the only FDA, HealthCanada and CE approved device thatprovides circulatory restoration inmorbidly ill patients with irreversible bi-ventricular failure, providing a life-saving bridge until a donor human heartbecomes available. In 2006, the EXCOR®TAH-t mobile driver was granted a CEmark, enabling European hospitals todischarge stable TAH-t patients to returnhome while they are awaiting atransplant. Visit our booth for updateson upcoming clinical studies for theFreedom ™ driver, the 50cc TAH-t, andthe pediatric VAD.

THORATEC CORPORATIONBOOTH 202PLEASANTON, CALIFORNIA

With more than 14,000 patient implantsand three decades of experience,Thoratec® Corporation offers thebroadest portfolio of mechanicalcirculatory support devices.Thoratec'sproduct line includes the CentriMag®Acute Circulatory Support Device,HeartMate® LVAS, Thoratec PVAD™ andIVAD™. Now the HeartMate II® is FDAapproved for both Bridge toTransplantation and Destination Therapy.

TRANSONIC SYSTEMS INCBOOTH 101ITHACA, NEW YORK

Transonic Systems’ flowmeters andsensors are the recognized goldstandard volume flow measurementapparatus for liquids in clinical andlaboratory settings. TransonicFlowmeters are used worldwide inlaboratory research, Hemodialysismonitoring, cardiovascular surgery,vascular access angioplasty,neurosurgery, critical care and as OEM components in VAD, CPB and numerous other controlled flow systems.

Featured in our booth will beTransonic laboratory research products– acute intra-operative, chronicallyimplantable, extracorporeal, as well as the PhysioGear™ and EndoGear™telemetry systems plus the TransonicInside OEM products and development capabilities.

SPECIAL INTERACTIVE EXHIBITFRIDAY, MAY 28TH1:30PM – 5:00PM

Demonstrating the Preparation andManagement During Transport of aCritically Ill Patient Who is Being Sent to a Tertiary Care Facility for aHighly Technical Procedure. Inaddition, Attendees Can See How Well They Perform Resuscitation-Related Procedures

Richard Aghababian, MD - Assoc Dean CME,Univ of Massachusetts Medical School

**James DuCanto, MD - Asst Clinical ProfLiver Transplant Anesthesia, Aurora StLuke's Medical Ctr

Jorge Yarzebski, NREMT-P - Emergency MedProg Coordinator, Univ of Massachusetts

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PROGRAM OUTLINETHURSDAY, MAY 27, 2010

8:00am – 12:00pm – Key Ballroom 8, 11, 12 – Level 2Opening General Session – Page 14

11:45am – 12:00pmASAIO Y Nosé International Fellowship Presentation – Page 14

12:15pm – 1:15pm – Tubman A, B – Level 3Working Luncheon – Page 14

1:30pm – 3:00pm – Key Ballroom 9 – Level 2Cardiac Slide Session 1 – Page 14

1:30pm – 3:00pm – Key Ballroom 10 – Level 2Cardiac Invited Speakers 1 – Page 15



8:00am – 5:00pm – Exhibit Hall – Level 2Cardiac Poster Session 1 – Page 15

1:30pm – 2:30pm – Holiday Ballroom 1 – Level 2Bioengineering Slide Session 1 – Page 16

1:30pm – 2:30pm – Holiday Ballroom 2 – Level 2Bioengineering Invited Speakers 1 – Page 17



8:00am – 5:00pm – Exhibit Hall – Level 2Bioengineering Poster Session 1 – Page 17

1:30pm – 5:05pm – Holiday Ballroom 3 – Level 2International Society for Apheresis Session – Page 18

1:30pm – 3:00pm – Key Ballroom 7 – Level 2Pulmonary Lecture & Slide Session 1 – Page 18

3:45pm – 5:15pm – Key Ballroom 7 – Level 2Pulmonary Slide Session 2 – Page 19

8:00am – 5:00pm – Exhibit Hall – Level 2Pulmonary Poster Session 1 – Page 19

5:30pm – 6:30pm – Key Ballroom South Foyer – Level 2Welcome Reception – Page 19

FRIDAY, MAY 28, 2010

8:00am – 10:00am – Holiday Ballroom 3 – Level 2Intensive Dialysis Day General Session – Page 20

12:15pm – 1:15pm – Johnson A, B – Lobby LevelRenal Working Luncheon – Page 20

1:30pm – 4:45pm – Holiday Ballroom 3 – Level 2Renal Parallel Session A – Page 20

1:30pm – 3:00pm – Holiday Ballroom 4 – Level 2Renal Parallel Session B – Page 20

3:45pm – 4:30pm – Holiday Ballroom 4 – Level 2Renal Slide Session 1 – Page 20

8:00am – 5:00pm – Exhibit Hall – Level 2Renal Poster Session 1 – Page 21

8:00am – 12:15pm – Key Ballroom 8, 11, 12 – Level 2General Session 2 – Page 21

11:45am – 12:15pm Barney Clark Award Presentation & the ASAIO Willem JKolff – Don B Olsen Award Presentation– Page 22

12:15pm – 1:15pm – Tubman A, B – Level 3Working Luncheon – Page 22

1:30pm – 5:00pm – Exhibit Hall – Level 2Special Interactive Exhibit – Page 22

1:30pm – 3:00pm – Key Ballroom 7 – Level 2Pulmonary Lecture & Slide Session 3 – Page 22

3:45pm – 4:45pm – Key Ballroom 7 – Level 2Special Session IFAO – ESAO – Page 22







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1:30pm – 4:15pm – Carroll A, B – Level 3Neural Session – Page 26

1:30pm – 4:15pm – Paca A, B – Level 3Pediatric Session – Page 26

5:30pm – 6:00pm – Carroll A, B – Level 3ASAIO Members Business Meeting – Page 27

SATURDAY, MAY 29, 2010

8:00am – 12:00pm – Key Ballroom 8, 11, 12 – Level 2General Session 3 – Page 27

9:00am – 10:30am New Venture Forum – Page 27

1:00pm – 3:00pm – Key Ballroom 10 – Level 2Commercialization Session – Page 27

1:00pm – 2:30pm – Key Ballroom 9– Level 2Cardiac Slide Session 5 – Page 28


1:00pm – 2:30pm – Key Ballroom 7 – Level 2Pulmonary Slide Session 4 – Page 29



BELDING H SCRIBNER, MD50TH ANNIVERSARY

In March 1960, Belding Scribner,head of the Division of Nephrologyat the University of Washington’sMedical School and Wayne Quinton,head of the University Hospital’sInstrument Shop, developed theTeflon Shunt that for the first timemade long term Hemodialysis forchronic renal failure possible. Thefirst patient, Clyde Shields, had ashunt implanted on March 9, 1960 by David Dillard, apediatric cardiac surgeon, and went on to live for 11 years onHemodialysis. The first Reports on this were published in the1960 Transactions of ASAIO. Some later developments byScribner and his colleagues included the world’s first out-ofhospital dialysis center, the use of proportioning pumps toprepare dialysate, home hemodialysis, home peritonealdialysis, the Tenckhoff catheter, the square meter-hour andmiddle-molecule hypotheses, and the Hickman catheter.Throughout the 1960’s and the early 1970’s, Seattle was theMecca for those interested in chronic dialysis. As Scribner saidlater the successful treatment of Clyde Shields represents “oneof the few instances in medicine where a single success wasall that was required to validate a new therapy.” From thatone patient there are now many more than a million and ahalf people throughout the world alive today wither ondialysis or with a kidney transplant.

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THU

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7 8:00am - 8:30amRAPID FIRE FLASH PRESENTATIONS

Five Abstracts have been selected for presentation in theNew Rapid Fire format. Authors will have five minutes topresent up to three slides. Please direct all questions to thespeaker at their poster board in the Exhibit Hall.

Hemolysis Rate after Biventricular CentrifugalVentricular Assist Device Implantation: Preliminary Dataof Clinical Study**Alexander Stepanenko, MD - Deutsches Herzzentrum Berlin

Clinical Predictors for Long Hospital Stay after LeftVentricular Assist Device (LVAD) Implantation**Ian Ledford - Intermountain Medical Ctr

Gas Exchange Performance of a Silicon NanoporousMembrane on a Liquid-Gas System**Fernando Casas, PhD - Cleveland Clinic

Different Flow Conditions Do Not Adversely AffectIntegrity and Activation of the Endothelial Surface of aNovel Artificial Gas Exchange Membrane**Bettina Wiegmann, MD - Hannover Medical School

Two-Pool Physical Simulator of the Inter-CompartmentalMass Transfer during Dialysis**Giustina Casagrande, PhD - Politecnico di Milano

8:30am - 12:15pmGENERAL SESSION 1 - THURSDAY"Opportunities for Innovation in the Face of Healthcare Reform"

Room: Key Ballroom 8, 11, 12 - Level 2Chairmen: William Holman, MD & Kurt Dasse, PhD

8:30am - 9:30amSYMPOSIUM

IT / Bioinformatics / HealthcareJohn Giobbi - President & CEO, Proxense LLC

Ryan Gallivan, MD - Medical Advisor Otolaryngology, Proxense LLC

9:30am - 10:00amKEYNOTE ADDRESS

The Future Impact of Healthcare Reform in theUnited States and the Regulatory Climate onMedical Device InnovationRoger Evans, PhD - CEO, Transplant Professionals LLC

10:00am - 10:45amVISIT EXHIBITS & POSTERS - ENJOY REFRESHMENTSExhibit Area: Key Ballroom 6 - Level 2

10:45am - 11:45amSYMPOSIUM

International Perspectives on Healthcare Reform

Changes in Healthcare Reform in EuropeEmma Birks, MRCP, PhD - Prof Medicine, Univ of Louisville

Changes in Healthcare Reform in Asia**Takeshi Nakatani, MD, PhD - Dir Organ Transplantation, Nat'lCardiovascular Ctr

11:45am - 12:15pmASAIO Y NOSÉ INTERNATIONAL FELLOWSHIP PRESENTATION**Takashi Nishimura, MD, PhD - Univ of Tokyo

12:15pm - 1:15pmWORKING LUNCHEON - Admission by Ticket

Room: Tubman A, B - Level 3

Sponsored by EvaHeart Medical Inc.Decreasing Complications with VAD Support - Role ofPhysician & Industry**Ranjit John, MD - Asst Prof Surgery, Univ of Minnesota

1:30pm - 5:15pmCARDIAC TRACK

1:30pm - 3:00pmCARDIAC SLIDE SESSION 1Short Term Circulatory Support

Room: Key Ballroom 9 - Level 2Moderators: Ranjit John, MD & Jeffrey Morgan, MD

1:30pm Use of the Levitronix Left Ventricular Assist Device for Treating PostcardiotomyCardiogenic ShockMehmet Akay - Texas Heart Inst

1:45pm Outcomes with the Levitronix CentriMag asCardiopulmonary Support (CPS) forCardiogenic Shock**Pere Ventura, BS - Intermountain Medical Ctr

2:00pm CentriMag-ECMO in Management of Acute HeartFailure Syndrome and Beyond**Aly El Banayosy, MD - Penn State Univ

2:15pm Recovery: To Explant or Not To ExplantJoshua Baker, MD - Massachusetts General Hospital

2:30pm Comparison of Circulatory Support with IABPand Impella 2.5LPStephanie Schampaert, BS - Eindhoven Univ of Technology

2:45pm Remote Cannulation for CentriMag Right Ventricular Support To Reduce InHospital MorbidityMatthew Schiralli, MD - Univ of Rochester

Dr. Nosé

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THU

RSDAY, MAY 27

1:30pm - 3:00pmCARDIAC INVITED SPEAKERS 1Room: Key Ballroom 10 - Level 2Moderators: Egemen Tuzun, MD & Peter Wearden, MD, PhD

1:30pm - 2:00pmSYMPOSIUM

Next Trial for REVIVE - IT

The Need and the ChallengeLeslie Miller, MD - Walters Chair CV Medicine, Georgetown Univ Hospital

REVIVE - IT Trial Update**Timothy Baldwin, PhD - Prog Dir NHLBI, NIH

2:00pm - 2:30pmDEBATE

Control Based on Venous Return - Is It Enough?**Robert Benkowski, BSME - COO, MicroMed Cardiovascular Inc

**Heinrich Schima, PhD - Prof Physics & Biomed Eng, Medical Univ Vienna

2:30pm - 3:00pmFDA's Role & Position on the Harmonization By Doing Initiative**Eric Chen, MS - Biomedical Engineer, FDA

3:00pm - 3:45pmVISIT EXHIBITS & POSTERS - ENJOY REFRESHMENTSExhibit Area: Key Ballroom 6 - Level 2

3:45pm - 5:15pmCARDIAC SLIDE SESSION 2Continuous Flow Pumps - Technical Consideration

Room: Key Ballroom 9 - Level 2Moderators: Greg Burgreen, PhD & Roberta Bogaev, MD

3:45pm Algorithm for HeartMate II LVAD SpeedAdjustments in the Perioperative PeriodJoshua Baker, MD - Massachusetts General Hospital

4:00pm Fluidic Performance Via Intrinsic Parameters ofa Magnetically Levitated Axial Flow VADMark Olles, PhD - Rochester Inst of Technology

4:15pm Methodology of Hemolysis Testing ofMechanical Circulatory Support Devices**Michael Sobieski, RN, CCP - Univ of Louisville

4:30pm Study on Improvement of Performance of AxialFlow Pump by Improving the MotorShin Furukawa, MS - Tokyo Denki Univ

4:45pm In Vitro Hemolysis Study in a NonpulsatileImplantable VAD: The Effect of Head Pressureand Flow**Branka Lukic, MS - Penn State Univ

5:00pm Evaluation of Ventricular Relaxation duringMechanical Cardiac Assist with Rotary Blood Pumps**Francesco Moscato, PhD - Medical Univ of Vienna

3:45pm - 5:15pmCARDIAC INVITED SPEAKERS 2Room: Key Ballroom 10 - Level 2Moderators: David Farrar, PhD & Edwin McGee, MD

3:45pm - 4:15pmProteomics to Study Cardiac RemodelingGiulio Agnetti, PhD - Postdoctoral Research Fellow, John Hopkins Univ

4:15pm - 4:45pmDesigning LVAD Trials - FDA Perspective**Eric Chen, MS - Biomedical Engineer, FDA

4:45pm - 5:15pmDo You Like Your LVAD With or Without Warfarin? New VAD Design to Avoid Systemic Anticoagulation**Egemen Tuzun, MD - Asst Dir CV Surgery Research Labs, TexasHeart Inst

8:00am - 5:00pmCARDIAC POSTER SESSION 1Room: Exhibit Area - Key Ballroom 6 - Level 2

Posters Available All Day

Board #

1 Newly Developed Mini-Axial Flow Pump: Apex Pump**Guorong Li, MD - Fu Wai Hospital

2 Hemolysis Rate after Biventricular CentrifugalVentricular Assist Device Implantation:Preliminary Data of Clinical Study**Alexander Stepanenko, MD - Deutsches Herzzentrum Berlin

3 Biventricular Mechanical Support with TwoImplantable Assist DevicesThomas Krabatsch, MD, PhD - German Heart Inst

4 Clinical Predictors for Long Hospital Stay afterLeft Ventricular Assist Device (LVAD)Implantation**Ian Ledford - Intermountain Medical Ctr

5 Causes of Mortality in Stable DestinationTherapy Patients**Douglas Horstmanshof, MD - Integris AdvancedCardiac Care

6 In Vivo Biocompatibility Evaluation of a NewSurfactant Polymer Coating Mimicking theGlycocalyx of Endothelial CellsAkira Shiose, MD, PhD - Cleveland Clinic

7 Stability of Unloading-Induced CardiacImprovement in Patients with Chronic Non-Ischemic Cardiomyopathy: Predictive Value forTranplant-Free Outcome after VentricularAssist Device ExplantationMichael Dandel, MD, PhD - Deutsches Herzzentrum Berlin

8 Development of the Implantable Axial FlowPump LVAD with the Hydrodynamic Bearings**Tomonori Tsukiya, PhD - Nat'l Cardiovascular Research Ctr

9 Low Rate of Thromboembolism with the INCORVentricular Assist Device: Design Changes andInitial Clinical Results**Andreas Arndt, PhD - Berlin Heart GmbH

10 Pre-Clinical Evaluation of MITIHEART® LVADAndrew Hunsberger, MS - MiTiHeart Corporation

11 A Novel Counterpulsation Drive Mode in aContinuous-Flow Left Ventricular Assist Device- Effect on Coronary CirculationMasahiko Ando, MD - Nat'l Cardiovascular Research Ctr

12 Left Ventricular Assist for Pediatric PatientsMasahide Komagamine, MD - Tokyo Women's Medical Univ

13 Left Ventricular Mechanical Support with theImpella Afford More Recovery Potential inFailing Hearts Than Extracorporeal MembraneOxygenationDai Kawashima, MD - Univ of Tokyo

14 The Effect of Continuous Flow Left Ventricular Assist Devices (CF-LVAD) on Aortic Valve Competence**Jerson Martina, MSc - Univ Medical Ctr Utrecht

15 Adult Candidates for Heart Transplantationwith Larger Body Surface Area Profit Morefrom Mechanical Circulatory Support**Takeshi Komoda, MD, PhD - Deutsches Herzzentrum Berlin

16 Does Ejection Fraction Predict Response toBiventricular Pacing after Cardiac Surgery?**Michelle Spotnitz, MD - UMDNJ - Robert Wood Johnson

17 Driveline Infection and Bacteremia inContinuous-Flow LVAD Patients IncreasesDuration of LVAD SupportForum Kamdar, MD - Univ of Minnesota

18 Reduction in Device-Related Infections withthe HeartMate II Left Ventricular Assist Device**Jeffrey Morgan, MD - Henry Ford Hospital

19 Development of a Novel Skin Penetrating Pad for Preventing the Exit Site Infection ofVAD DrivelineToshihide Mizuno, DVM, PhD - Nat'l CardiovascularResearch Ctr

20 Pump Flow Estimation in cf-LVAD PatientsRequires Dynamic Pump ModelsMarcel Rutten, PhD - Eindhoven Univ of Technology

21 Renal Dysfunction in Patients ReceivingContinuous-Flow Left Ventricular AssistDevices Adversely Affects SurvivalForum Kamdar, MD - Univ of Minnesota

22 Self-Expanding Venous Cannulae for Pediatric CPBSaad Abdel-Sayed, PhD - Univ Hospital CHUV

23 Turbulence Modeling as a Source of Error inFDA's "Critical Path" InterlaboratoryComputational Study of Flow in a Nozzle ModelSandy Stewart, PhD - FDA

24 An Ovine Model of Postinfarction RemodelingBart Meyns, MD, PhD - Univ Hospitals Leuven

25 Management of Patent Foramen Ovale duringHeartMate LVAD Placement**Walter Dembitsky, MD - Sharp Memorial Hospital

26 Novel Combined Maglev Actuator for the BiVACOR**Toru Masuzawa, PhD - Ibaraki Univ

27 Differences in Regional Myocardial Perfusion,Metabolism, MVO2 and Edema after 12 HourCoronary Sinus Machine Perfusion Preservationof Canine HeartsMichael Cobert, MS - Univ of Texas Southwestern

28 Sensorless Fuzzy Logic Control of a RotaryVAD: In Vivo Performance**Fernando Casas, PhD - Cleveland Clinic

29 HeartMate II LVAD Support in Patients withMechanical Mitral ValvesMehmet Akay - Texas Heart Inst

30 Comprehensive Fluid Dynamic Assessment of aBileaflet Mitral BioprosthesisJonathan Hill - Univ of South Carolina

1:30pm - 4:45pmBIOENGINEERING TRACK

1:30pm - 2:30pmBIOENGINEERING SLIDE SESSION 1Neural & Auditory Bioengineering

Room: Holiday Ballroom 1 - Level 2Moderators: Steven Koenig, PhD & Antonio Ferreira, PhD

1:30pm Development of a New AntithrombogenicCerebral Stent Using Ion Beam SurfaceModification - A Five Year Animal Study**Yochi Sugita, MD - Baylor College of Medicine

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1:45pm A Novel Neurovascular Stent Covered inStretchable Thin Film NiTi Significantly DecreasesFlow into a Wide-Neck Aneurysm In Vitro**Youngjae Chun, PhD - UCLA

2:00pm Liposome-Encapsulated Hemoglobin AlleviatesHearing Loss after Transient Cochlear Ischemiaand Reperfusion**Akira Kawaguchi, MD, PhD - Tokai Univ

2:15pm Brain Based Electrospun Tissue Scaffolds: AParametric Study**Kevin Aroom, MS - Univ of Texas

1:30pm - 2:30pmBIOENGINEERING INVITED SPEAKERS 1Room: Holiday Ballroom 2 - Level 2Moderators: James Antaki, PhD & Roshni Patel, MS

1:30pm - 2:30pm Conclusions Drawn at the “FirstInternational ECMO Conference”Jointly Sponsored by ASAIO & PennState Hershey

2:30pm - 3:00pm Artificial MusclesMohsen Shahinpoor, PhD - Richard C Hill Prof & Chair Mech Eng, UMaine

3:00pm - 3:45pm

VISIT EXHIBITS & POSTERS - ENJOY REFRESHMENTSExhibit Area: Key Ballroom 6 - Level 2

3:45pm - 5:15pmBIOENGINEERING SLIDE SESSION 2Blood Substitutes & Pediatric Cardiopulmonary Bypass

Room: Holiday Ballroom 1 - Level 2Moderators: Conrad Zapanta, PhD & Keefe Manning, PhD

3:45pm Hemotech-Blood Substitute Role in thePrevention of Platelet Activation inPercutaneous Coronary Intervention (PCI)Patients**Jan-Stanley Simoni, DVM, PhD - Texas Tech Univ

4:00pm Delaying Blood Transfusion during ExtremeAnemia with Perfluorocarbon Emulsion**Pedro Cabrales, PhD - Univ of California

4:15pm In Vitro Observations of the Fluid Mechanicsinside the Penn State PVAD Using BloodAnalogs of Varying Hematocrits**Breigh Roszelle, BS - Penn State Univ

4:30pm Left Ventricular Mechanoenergetic Cost ofBlood and Plasma Viscosity duringHemodilution**Pedro Cabrales, PhD - Univ of California

4:45pm Effect of Liposome-Encapsulated Hemoglobinon Antigen-Presenting Activity**Akira Kawaguchi, MD, PhD - Tokai Univ

5:00pm Preliminary Experimental Validation of aPressure-Regulated Volume-Controlled LiquidVentilation Mode**Raymond Robert, PhD, MSc - Univ de Sherbrooke

3:45pm - 4:45pmBIOENGINEERING INVITED SPEAKERS 2Room: Holiday Ballroom 2 - Level 2Moderators: Kenneth Solen, PhD & Mickey Ising, BS

3:45pm - 4:15pm

Translational Biomedical Engineering for Artificial OrganResearch & DevelopmentBastian de Mol, MD, PhD - Prof CT Biomechanics, Academic Medical Center

4:15pm - 4:45pm

Bioengineering Challenges In Engineered Tissue ValvesMichael Sacks, PhD - John A Swanson Chair Bioeng, Univ of Pittsburgh

8:00am - 5:00pmBIOENGINEERING POSTER SESSION 1Artificial Organ & Blood Substitute Development

Room: Exhibit Area - Key Ballroom 6 - Level 2


Board #

31 Pre-Transplant Kidney-Specific Treatment ToEliminate the Need for SystemicImmunosuppression** Lauren Brasile, PhD - Breonics

32 Apparatus for Measuring the Effect of ApicalTorsion on Functioning Isolated HeartsDennis Trumble, MS - Carnegie Mellon Univ

33 Development of a Highly Efficient Non-ViralVector for Cardiac Gene TherapyZhou Min, MD, PhD - Nat'l Cardiovascular Research Inst

34 Novel Percutaneous Implant Model for Pre-Clinical Testing**Kelly Chapman, BSME - IncuMed ResearchOrganization

35 Different Flow Conditions Do Not AdverselyAffect Integrity and Activation of theEndothelial Surface of a Novel Artificial GasExchange Membrane**Bettina Wiegmann, MD - Hannover Medical School

36 VA ECMO Setting Optimalization in PatientsSuffering from Cardiogenic Shock**David Macku, MD, MSc - Czech Technical Univ

37 Molecular Surgery for the Treatment ofMalignant Tumors**Kazuhide Ohta, DVM, PhD - Baylor College of Medicine

38 Liver Regeneration by Portal Cell Therapy:Transplanted Human Cord Blood DerivedUnrestricted Somatic Stem Cells GenerateHepatocyte-Like Cells throughTransdifferentiation but Not Cell FusionAlireza Ghodsizad, MD - Univ of Heidelberg

39 Two-Pool Physical Simulator of the Inter-Compartmental Mass Transfer during Dialysis**Giustina Casagrande, PhD - Politecnico di Milano

40 Plasmapheresis through a MicrofabricatedSilicon Nanofilter**Edward Leonard, PhD - Columbia Univ

41 Regulated Delivery of IGF-1 Using LocalizableMicroencapsulated Genetically Modified Cells**Roshni Patel, MS - Brown Univ

42 Expanding Capsule for Diet Control**Tomoyuki Yambe, MD, PhD - Tohoku Univ

43 Surgical Correction of Ptosis by IonicPolyacrylonitrile Artificial MusclesMohsen Shahinpoor, PhD - Univ of Maine

44 Sustained Release Nitric Oxide from LongLived Circulating Nanoparticles**Pedro Cabrales, PhD - Univ of California

45 Drinking Mechanism for an ArtificialEsophagus and Super Stent System**Tomoyuki Yambe, MD, PhD - Tohoku Univ

46 Effects of Storage Time and ABO Group onMale and Female Donor Red Blood CellSuspension Viscoelasticity**Amanda Daly, BS - Univ of Pittsburgh

47 Study of the Influence of LecithinConcentration on the Stability of Perfluoroctyl Bromide EmulsionsCamila Castro, MSc - Univ de Los Andes

1:30pm - 5:05pmINTERNATIONAL SOCIETY FOR APHERESIS SESSIONApheresis Therapy I

Room: Holiday Ballroom 3 - Level 2Moderators: Andre Kaplan, MD & Patrick Moriarty, MD

1:30pm - 1:50pmSelective Apheresis Technologies - Current Status andFuture PerspectivesWolfgang Ramlow, MD - Medical Director, Clinic for Neph, Dialysis &Apheresis

1:50pm - 2:10pmApheresis Therapy in Immune-Mediated Vasculitidies**Andre Kaplan, MD - Prof Medicine, University of Connecticut Health Ctr

2:10pm - 2:30pmApheresis Therapy in Solid Organ TransplantationJan Kielstein, MD, PhD - Asst Prof Medicine, Medical School Hannover

2:30pm - 2:50pmCurrent Status of Apheresis Therapy in Sepsis and Liver Failure**Dieter Falkenhagen, MD, PhD - Head Clinical Med & Biotech,Danube Univ at Krems

3:00pm - 3:45pmVISIT EXHIBITS & POSTERS - ENJOY REFRESHMENTSExhibit Area: Key Ballroom 6 - Level 2Apheresis Therapy II

Moderators: Paul Malchesky, D Eng & Wolfgang Eamlow, MD

3:45pm - 4:05pmAdsorptive Cytapheresis - An Effective Treatment Optionin Inflammatory Bowel DiseasesKen Fukunaga, MD, PhD - Asst Prof Medicine, Hyogo College of Medicine

4:05pm - 4:25pmApheresis Therapy in Neurological Diseases - CurrentStatus and Future PerspectivesChang-Sung Koh, MD, PhD - Prof Medicine, Shinshu University

4:25pm - 4:45pmImmunoadsorption in Idiopathic Dilated CardiomyopathyLars Herda, MD - Univ Greifswald

4:45pm - 5:05pmRheological Effects of Lipid ApheresisPatrick Moriarty, MD - Clinical Pharmacology, Univ of Kansas

1:30pm - 5:15pmPULMONARY TRACK

1:30pm - 3:00pmPULMONARY LECTURE & SLIDE SESSION 1Room: Key Ballroom 7 - Level 2Moderators: Joseph Zwischenberger, MD & Jonathan Haft, MD

Sponsored by MC3 Inc.

1:30pm - 2:00pmUsing ECMO as an Ambulatory Bridge to LungTransplantationBartley Griffith, MD - Prof & Chief Cardiac Surgery, Univ of Maryland

2:00pm ECMO in Patients with Shock, Predictors of SurvivalDavid Spurlock, MD - Univ of Michigan

2:15pm Retrospective Analysis of Venovenous VersusVenoarterial Extracorporeal MembraneOxygenation for Treatment of Post LungTransplantation Primary Graft Failure**Matthew Bacchetta, MD - Columbia Univ

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2:30pm Transfusion Requirements with a NewMiniaturized System for ExtracorporealMembrane Oxygenation (ECMO) in AdultRespiratory FailureDaniele Camboni, MD - Univ Hospital Regensburg

2:45pm An Ultra-Durable Heparin-Free Pediatric andAdult ECMO Systems and Its ClinicalApplication in Japan**Nobumasa Katagiri, ME - Nat'l Cardiovascular CtrResearch InstASAIO Willem J Kolff - Don B Olsen Award Recipient


3:45pm - 5:15pmPULMONARY SLIDE SESSION 2Room: Key Ballroom 7 - Level 2Moderators: Michael Sobieski, RN, CCP & Keith Cook, PhD

3:45pm Extracorporeal Life Support as Rescue TherapyFollowing Sudden Cardiac Arrest DeathPasquale Totaro, MD, PhD - IRCCS Foundation S Matteo

4:00pm Percutaneous Cardiopulmonary Support UsingEmergency Bypass System: Clinical Portfoliofrom Single Center Experience of 103 Cases**Cheong Lim, MD, PhD - Seoul National Univ

4:15pm Safe Transport of Critically Ill Patients onExtracorporeal Membrane Oxygenation Support**Matthew Bacchetta, MD - Columbia Univ

4:30pm Efficacy of Extracorporeal CO2 Removal withthe Hemolung: Results in Animals**Peter Wearden, MD, PhD - Children's Hospital ofPittsburgh

4:45pm Extracorporeal Support in Non-HeparinizedDonors after Cardiac (DCD)**Alvaro Rojas, MD - Univ of Michigan

5:00pm A Microfluidic Respiratory Assist Device with High Gas Permeability for Artificial Lung ApplicationsJeffrey Borenstein, PhD - Draper Laboratory

8:00am - 5:00pmPULMONARY POSTER SESSION 1Room: Exhibit Area - Key Ballroom 6 - Level 2


Board #

48 Effects of the Molecular Mass of Tense-StatePolymerized Bovine Hemoglobin on BloodPressure and Vasoconstriction**Pedro Cabrales, PhD - Univ of California

49 Gas Exchange Performance of a SiliconNanoporous Membrane on a Liquid-Gas System**Fernando Casas, PhD - Cleveland Clinic

50 Transesophageal Echo Guidance FacilitatesPercutaneous Placement of the Avalon Elite™Cannula for ECMO**Mark Bonnell, MD - Univ of Kentucky

51 Mathematical Model of an Extra-CorporalSupport SystemAlejandro Mendoza Garcia - Technical UniversitaMunchen

52 A New Venovenous Perfusion-Induced SystemicHyperthermia Circuit for Advanced Lung CancerTherapy**Cherry Croft, PhD - Univ of Kentucky

53 Silicone Hollow Sphere Fibers (SHSF): A NewConcept for Capillary Membrane Oxygenators(CMO)Khosrow Mottaghy - RWTH Aachen Univ

54 Computational Evaluation of the PediatricScaled Pump-Lung (PediPL) Device**Mustafa Ertan Taskin, PhD - Univ of Maryland

55 Structural Analysis for Constructing a BalloonType Extracorporeal Membrane OxygenatorUsing CFD Analysis**Young Ran Park, MS - Chonbuk National Univ

56 Impedance and Right Ventricular Function inthe Hypertensive Pulmonary SystemBegum Akay, MD - Univ of Michigan

57 Novel Bridge to Lung Transplantation inPulmonary Hypertension Using AtrialSeptostomy and Veno-Venous ExtracorporealLife SupportPeter Sassalos, MD - Univ of Michigan

58 Converting the Redy 2000 Dialysis Machine toan Artificial Gills Machine That DeliversDissolved Oxygen in Aquatic Phase**Mohamed Elnachef, MD - SIOF Institute

5:30pm - 6:30pmASAIO WELCOME RECEPTION - ADMISSION BY TICKETRoom: Key Ballroom South Foyer - Level 2

INTENSIVE DIALYSIS DAY

8:00am - 10:00amRENAL GENERAL SESSION - FRIDAY"Intensive Outpatient Dialysis, Long and Short"

Room: Holiday Ballroom 3 - Level 2Chairman: William Fissell, MD

8:00am - 9:00amImproving Outcomes Through Intensive HemodialysisPhilip McFarlane, MD - Medical Dir Nephrology, Univ of Toronto

9:00am - 10:00amHome Hemodialysis and Short Daily Hemodialysis**Christopher Blagg, MD - Executive Director, Northwest Kidney Centers


10:45am - 12:00pmCIRCULATE AND VISIT EXHIBITS & POSTERS

12:15pm - 1:15pmRENAL WORKING LUNCHEON - Admission by ticket

A Nurse Manager's Perspective on Intensive Maintenance Hemodialysis

Room: Johnson A, B - Lobby Level

Sponsored by Fresenius Medicare CareIntroduction

David Smith, RN, CHN - Manager Operations, Fresenius Medical Care NA

Lynda Newman, MSN, RN, ACNS-BC, CNN - Clinical Coordinator HomeDialysis, Case Medical Ctr

RENAL PARALLEL SESSIONS

1:30pm - 4:45pmRENAL TRACK ANuts and Bolts of Intensive Outpatient Therapies

Room: Holiday Ballroom 3 - Level 2Moderator: Andre Kaplan, MD

1:30pm - 2:00pmTenuous Economics of a Nocturnal ProgramRobert Provenzano, MD - Dir Nephrology, St Johns Hospital & Medical Center

2:00pm - 2:30pmPractical Matters In Setting Up a Nocturnal ProgramKarl Schwarze, MD - Chief Nephrology, Akron Nephrology Associates

2:30pm - 3:00pmDiscussion


3:45pm - 4:15pmTechnical and Practical Aspects of Daily DialysisRobert Provenzano, MD Dir Nephrology, St Johns Hospital & Medical Ctr

4:15pm - 4:45pmNocturnal Home Hemodialysis with an Eye Toward LongTerm Survival of the ProgramLynda Newman, MSN, RN, ACNS-BC, CNN - Clinical Coordinator HomeDialysis, Case Medical Ctr

1:30pm - 3:00pmRENAL TRACK B. NOVEL MEMBRANE TECHNOLOGIESRoom: Holiday Ballroom 4 - Level 2Moderator: William Fissell, MD

1:30pm - 2:00pmControlled Pore Geometries for Enhanced Selectivity**William Fissell, MD - Assoc Staff, Cleveland Clinic

2:00pm - 2:30pmAnodized Alumina Membranes**Zhongping Huang, PhD - Asst Prof Mech Eng, Widener Univ

2:30pm - 3:00pmAnnealed Silicon Nanoporous MembranesChristopher Striemer, PhD - VP Engineering, SIMPore Inc


3:45pm - 4:30pmRENAL SLIDE SESSION 1Room: Holiday Ballroom 4 - Level 2

3:45pm Tidal Peritoneal Dialysis (TPD) Using Low Tidal(TV) and Reserve (RV) Volumes: Towards anAutomated Wearable Artificial Kidney (AWAK)**Martin Roberts, PhD - VA Greater Healthcare Systems

4:00pm Plasma Levels of Piperacillin and TazobactamIn Vitro Model of CVVHDFGisella Vischini, MD - S Eugenio Hospital

4:15pm Possible Treatment of Hyperphosphatemia dur-ing Dialysis Using a Phosphate BindingColumn and an Improved DialysateMatthew Fahrenkopf - Carnegie Mellon Univ

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8:00am - 5:00pmRENAL POSTER SESSION 1Room: Exhibit Area - Key Ballroom 6 - Level 2


Board #

59 Clinical Evaluation of a Vascular Access Systemfor Hemodialysis**Abram Janis, MS - IncuMed Research Organization

60 Comparison of Clearance and FluidDistributions of Newly Designed High FluxHemodialyzers**Zhongping Huang, PhD - Widener Univ

61 Patient Satisfaction with Renal ReplacementTherapy, Education and TrainingGreg Abbott, MBA - Baxter Healthcare

62 Assessment of Change in Hydration Status inHemodialysis Patients Using BioimpedanceTechniquesSamer Abbas, PhD - Renal Research Inst

63 A Selective Cytopheretic Inhibitory Device(SCD) Accelerates Renal Recovery andImproves Mortality in ICU Patients with AKIand MOF in an Exploratory Clinical Study**David Humes, MD - Univ of Michigan

64 Effect of Selective Renal Artery Perfusion withExtracorporeal Circuit on Renal Function underAcute Cardio-Renal SyndromeShigeru Hanada, MD - Nat'l Cardiovascular Research Inst

65 Optimized Biocompatibility and Performance of aNew Steam Sterilized Plasma Separation MembraneMarkus Storr - Gambro Dialysatoren GmbH

66 Mechanism of Action of a SelectiveCytopheretic Device to Ameliorate MultiorganDysfunction in Septic Shock**Juyoung Jung, DVM, PhD - Univ of Michigan

67 Does a Reduced Sodium Dietary Intake ImpactBlood Pressure and Total Body Water?Natalia Rakova, MD - Russian Academy of Sciences

68 Initial In Vivo Evaluation of a HemodialzingSystem for Transportable Treatment**George Pantalos, PhD - Univ of Louisville

69 Insulinogenic Index in Non-Diabetics duringHemodialysis**Daniel Schneditz, PhD - Medical Univ of Graz

70 Cryoreactive Albumin Removal Apheresis(CRARA) Therapy for the Prevention ofDiabetic Complication**Hiroshi Miyamoto, PhD - Baylor College of Medicine

71 Dialyzer End-Caps Revisited**Alexandra Peyser, BS - Columbia Univ

72 Development of the 2nd GenerationGranulocytapheresis ColumnJunji Takaba - Baylor College of Medicine

8:00am - 8:30amRAPID FIRE FLASH PRESENTATIONS

Five Abstracts have been selected for presentation in theNew Rapid Fire format. Authors will have five minutes topresent up to three slides. Please direct all questions tospeakers at their poster board in the Exhibit Hall.

Clinical Evaluation of a Vascular Access System forHemodialysis**Abram Janis, MS - IncuMed Research Organization

Modeling and Numerical Analysis of Platelet Activation,Adhesion and Aggregation in Artificial Organs**Jaewook Nam, PhD - Rice Univ

Impact of a Continuous Flow Left Ventricular AssistDevice on Right Ventricular Function**Jeffrey Morgan, MD - Henry Ford Hospital

Evaluation of Oxygen Exchange in Total LiquidVentilation with a Bubble Gas Exchanger**Philippe Micheau, PhD - Univ de Sherbrooke

Development of a 2nd Gen. Data Acquisition Platform forthe Pediaflow VAD**Salim Olia, BS - Univ of Pittsburgh

8:30am - 12:15pmGENERAL SESSION 2 - FRIDAY"Disruptive Technologies: Developing the NextBreakthrough"

Room: Key Ballroom 8, 11, 12 - Level 2Chairmen: William Wagner, PhD & William Weiss, PhD

8:30am - 9:00amKEYNOTE ADDRESS

Enhancing Innovation and Its Commercial Application inan Academic Medical CenterChristopher Coburn, PhD - Executive Director Innovations, Cleveland Clinic

9:00am - 9:30amThe Safe Surgeon and Surgical Innovation**William Holman, MD - Prof CT Surgery, Univ ofAlabama at Birmingham - President ASAIO

9:30am - 10:00amECMO as Organ Resuscitation for Donors after Cardiac DeathConstantino Fondevila, MD, PhD - Assoc Prof Surgery, Univ of Barcelona


10:45am - 11:15amASAIO HASTINGS LECTURE

Artificial Lung - A New Inspiration**Joseph Zwischenberger, MD - Chair Surgery, Univ of Kentucky

11:15am - 11:45am50th Scribner Anniversary - Dialyzing His First Patientswith Chronic Renal Failure Using the Scribner - Quinton Shunt**Christopher Blagg, MD - Executive Director, Northwest Kidney Centers

11:45am - 12:15pmBARNEY CLARK AWARD PRESENTATIONPresented by: **Don Olsen, DVM - President, UtahArtificial Heart Inst

Presented to:

**Eli Friedman, MD - Prof Medicine, DownstateMedical Center

ASAIO WILLEM J KOLFF - DON B OLSEN AWARD PRESENTATIONPresented by: **Don Olsen, DVM to:**Nobumasa Katagiri, ME - Nat'l Cardiovascular Ctr Research Inst

12:15pm - 1:15pmWORKING LUNCHEON - Admission by ticket

Room: Tubman A, B - Level 3Physicians Present - Training & Education with Devices / Therapy**Mark Slaughter, MD - Prof & Chief Thoracic & CV Surg, Univ ofLouisville

1:30pm - 5:00pmSPECIAL INTERACTIVE EXHIBIT: Demonstrating the Preparation and Management DuringTransport of a Critically Ill Patient Who is Being Sent toa Tertiary Care Facility for a Highly Technical Procedure.In addition, Attendees Can See How Well They PerformResuscitation-Related ProceduresRoom: Exhibit Area - Key Ballroom 6 - Level 2

Integration of Medical Education and Technology, Recent InnovationsRichard Aghababian, MD - Assoc Dean CME, Univ of MassachusettsMedical School

**James DuCanto, MD - Asst Clinical Prof Liver TransplantAnesthesia, Aurora St Luke's Medical Ctr

Jorge Yarzebski, NREMT-P - Emergency Med Prog Coordinator, Univ ofMassachusetts

A. Preparation and Management during Transport of aCritically Ill Patient

B. Demonstration of Resuscitation-Related Procedures


1:30pm - 3:00pmPULMONARY LECTURE & SLIDE SESSION 3Room: Key Ballroom 7 - Level 2Moderators: William Federspiel, PhD & Guruprasad Giridharan, PhD

1:30pm - 2:00pmNeurally Adjusted Ventilatory AssistChrister Sinderby, BSc - Staff Scientist, St Michael's Hospital

2:00pm Assessment of the Gas Exchange Performance ofthe TLV System with a Slanted Operating TableRyo Yokoi, BS - Tokyo Denki Univ

2:15pm Veno-Venous Peripheral ExtracorporealMembrane Oxygenator (ECMO) for AcuteRespiratory Failure Due to Influenza A (H1N1)Virus Infection: Early Satisfactory Results inOur Single-Centre ExperiencePasquale Totaro, MD, PhD - IRCCS Foundation S Matteo

2:30pm 30 Day In-Vivo Performance of an IntegratedPediatric Pump-Lung forCardiac/Cardiopulmonary SupportTao Zhang, PhD - Univ of Maryland

2:45pm In Vitro Testing Results of the HemolungRespiratory Assist System**Paul Bieniek - Alung Technologies Inc


3:45pm - 4:45pmSPECIAL SESSION - IFAO - ESAORoom: Key Ballroom 7 - Level 2Moderator: Stephen Ash, MD

3:45pm - 4:15pmRegenerative Medicine and ESAO Conference 2011Rui Reis, PhD - Assoc Prof, Univ of Minho

4:15pm - 4:45pmArtificial Organs and IFAO**Jörg Vienken, PhD - President IFAO

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1:30pm - 3:00pmCARDIAC SLIDE SESSION 3Continuous Flow LVAD - Clinical Implication

Room: Key Ballroom 9 - Level 2Moderators: Geetha Bhat, MD, PhD & Scott Corbett, PhD

1:30pm Lack of Ischemic Strokes in Patients Implantedwith the HeartMate II LVAD: A Single CenterExperiencePaul Nolan, PhD - Univ of Arizona

1:45pm Does Coronary Flow Increase in cf-LVAD Support?

**Egemen Tuzun, MD - Texas Heart Inst

2:00pm How Effective Are Continuous Flow LeftVentricular Assist Devices in Lowering HighPulmonary Artery Pressures in HeartTransplant Candidates?

**Geetha Bhat, MD, PhD - Advocate Christ Medical Ctr

2:15pm Efficacy of Continuous-Flow LVADs in End-Stage Heart Failure Patients with SeverePulmonary HypertensionForum Kamdar, MD - Univ of Minnesota

2:30pm Tricuspid Valve Replacement Coincident withHeartMate II LVAD Insertion**Walter Dembitsky, MD - Sharp Memorial Hospital

2:45pm Low Operative Mortality in Patients Supportedwith a Left Ventricular Assist Device RequiringPump Exchange**Antone Tatooles, MD - Advocate Christ Medical Ctr

1:30pm - 2:45pmCARDIAC INVITED SPEAKERS 3Room: Key Ballroom 10 - Level 2Moderators: George Pantalos, PhD & Todd Massey, MD

1:30pm - 1:50pmDual Continuous Flow: Total Artificial Heart with Induced Pulsatility**O Howard Frazier, MD - Chief Center for Cardiac Support, Texas Heart Inst

1:50pm - 2:15pmRemote Monitoring SessionGregory Ewald, MD - Assoc Prof Medicine, Washington Univ

2:15pm - 2:45pmHuman Factors and When to Evaluate the Device**Sonna Patel-Raman, PhD - Biomedical Engineer, FDA - FDA Perspective

**Jeffrey LaRose, MSME - Exec VP, CSO, HeartWare Inc - Industry Perspective


3:45pm - 5:30pmCARDIAC SLIDE SESSION 4VADs - Experimental

Room: Key Ballroom 9 - Level 2Moderators: Steven Conrad, MD, PhD & John Pristas, MBA

3:45pm - 4:00pm

HypothermiaMarie Mullen, MD - Assoc Prof Emergency Medicine, Univ of Massachusetts

4:00pm Opening Time and Average Load on the AorticValve during cf-LVAD Support

**Egemen Tuzun, MD - Texas Heart Inst

4:15pm A New Technology for Preventing VAD DriveLine Infection Using Plasma-Based IonImplantation**Yoichi Sugita, MD - Baylor College of Medicine

4:30pm Acute Animal Experiments of a MagneticallyLevitated Axial Flow VAD**Don Olsen, DVM - Utah Artificial Heart Inst

4:45pm 1st US Implants of the Levacor VAD**Douglas Horstmanshof, MD - Integris AdvancedCardiac Care

5:00pm Optimizing Cardiovascular Interaction withVentricular Assist DevicesKai Chun Wong - Helmholtz Inst

5:15pm Hemorheological Evaluation of the 3rd Gen.Pediaflow VAD Performance**Salim Olia, BS - Univ of Pittsburgh



Board #

73 Miniature Cardiopulmonary Bypass System for Mice**Akira Kawaguchi, MD, PhD - Tokai Univ

74 Development of a Novel Inflow Cannula for LessInvasive and Antithrombogenic LVAD Support**Yoshiaki Takewa, MD - Nat'l Cardiovascular Research Ctr

75 Modeling and Numerical Analysis of PlateletActivation, Adhesion and Aggregation inArtificial Organs**Jaewook Nam, PhD - Rice Univ

76 Development of Native Heart Load Control Systemwith Continuous Flow Ventricular Assist Devicefor Bridge to Recovery of Failing Heart**Takashi Nishimura, MD, PhD - Univ of TokyoASAIO Y Nosé International Fellowship Recipient

77 Impact of a Continuous Flow Left VentricularAssist Device on Right Ventricular Function**Jeffrey Morgan, MD - Henry Ford Hospital

78 Rescue Therapy with TandemHeart™ in Patientswith Severe Post-Heart Transplant Rejectionand Cardiogenic ShockMehmet Akay - Texas Heart Inst

79 Influence of the Aortic Root Compliance onHemolysis of Heart Valve Prostheses: An InVitro StudyMarcus Hormes, Dipl Ing - RWTH Aachen Univ

80 Time-Dependent Differences in the Cause ofDeath after Left Ventricular Assist DeviceImplantation**Ian Ledford - Intermountain Medical Ctr

81 LEVACOR™ VAD - Preclinical Qualification forUS Study**Phillip Miller, MS - WorldHeart Corporation

82 Preclinical Biocompatibility Assessment ofPediatric VADS in the Ovine Model**Carl Johnson, BS - Univ of Pittsburgh

83 Use of External Pressure Application ToAugment Fontan Hemodynamics**Sonya Bhavsar, BS - Virginia Commonwealth Univ

84 In Vitro and Ex Vivo Development of a NovelBioactive Ventricular Assist Device ConduitMatthew Phaneuf, BS - BioSurfaces Inc

85 Biventricular Support Using ImplantableContinuous-Flow Ventricular Assist DevicesShunsuke Saito, MD - Osaka Univ

86 Speed Modulation of the Continuous-Flow TotalArtificial Heart To Simulate a PhysiologicArterial Pressure WaveformAkira Shiose, MD, PhD - Cleveland Clinic

87 Accidental Intraabdominal Tunneling ofDriveline in Patient Supported for over 4 Yearswith DuraHeart Left Ventricular Assist Device(LVAD) Detected during Pump Exchange**Alexander Stepanenko, MD - Deutsches Herzzentrum Berlin

88 Arterial Pressure Correlates with CardiacOutput during Biventricular PacingOptimizationBarry Breaux - Columbia Univ

89 A Dynamic Study on the Hemolytic Effect ofNegative Pressure on Blood**Tim Kaufmann, Dipl Phys - RWTH Aachen Univ

90 Development of a Wearable Pneumatic TotalArtificial Heart System with an Ultra CompactDrive UnitHirohito Sumikura, PhD - Nat'l Cardiovascular Research Ctr

91 Biochemical and Functional Changes in RedBlood Cells and Platelets Induced by IodinatedRadiographic Contrast Media (ICM)**Jan-Stanley Simoni, DVM, PhD - Texas Tech Univ

92 A Design Tool for Miniaturized RBP ImpellerSuspension Using Fluid Film BearingsDaniel Timms, Heimholtz Inst

93 Percutaneous Cavopulmonary Assist System forFailing Fontan Circulation**Dongfang Wang, MD, PhD - Univ of Kentucky

94 Peripheral Approach to the Impella 5.0LPJoshua Baker, MD - Massachusetts General Hospital

95 Development of an Ultra-Compact PneumaticPressure Generation System To Drive aPneumatic Blood Pump for VAD and TAH**Akihiko Homma, PhD - Nat'l Cardiovascular Research Ctr

96 Development of a Rapid, Safe, FiberopticGuided, Single-Incision Cricothyrotomy MethodUsing a Large Ovine Model: A Pilot Study**James DuCanto, MD - Aurora St Luke's Medical Ctr

97 Simulation of the Flow in the CardiovascularSystem for Cardiopulmonary Bypass andCardiac Assist Using a Two-Way Fluid-Structure-Interaction Model**Tim Kaufmann, Dipl Phys - RWTH Aachen Univ

98 Computational Modeling of Nitinol Stents forPercutaneous Heart Valves**Javid Moraveji - Univ of South Carolina

99 Simulation of a Pneumatic Driver for aPediatric Ventricular Assist Device**William Weiss, PhD - Penn State Univ

100 Ultrafiltration Techniques in a Large-AnimalModel of Cardiac Replacement**Jeff Conger, BS, RRT - Texas Heart Inst

101 Investigation of Effects of Passive Filling LeftVentricular Assist Device on Native FailingHeart in Mock CirculationYu Funabashi - Tokyo Denki Univ

102 In Vivo Calcification of Polyurethane TrileafletHeart Valves**Caitlyn Bosecker, SMME - Abiomed Inc

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1:30pm - 3:00pmBIOENGINEERING SLIDE SESSION 3Ventricular Assist Device Bioengineering

Room: Holiday Ballroom 1 - Level 2Moderators: Marina Kameneva, PhD & Timothy Maul, PhD

1:30pm Predictors of Late Exit Site InfectionsAssociated with Ventricular Assist Device(VAD) TherapyPramond Bonde, MD - Univ of Pittsburgh

1:45pm Early Unloading of Infracted Hearts PreventsCardiac Remodeling and Preserves CalciumHomeostasisGiacomo Bianchi, MD - Univ of Maryland

2:00pm Impella LVAD Effectively Decreases Strain inthe Left Ventricle after Myocardial Infarction**Zhongjun Wu, PhD - Univ of Maryland

2:15pm Optimal Identification of Need for RightVentricular Support Using Cost-SensitiveDecision Tree**Yajuan Wang, MS - Carnegie Mellon UnivASAIO Young Innovator First Time Author Fellowship Recipient

2:30pm Biodegradable and ThermoresponsiveHydrogels Designed for Injection Therapy ToImprove Function in Ischemic Cardiomyopathy**William Wagner, PhD - Univ of Pittsburgh

2:45pm Sensitivity of Hemodynamics and Wall Stressto the Speed of Continuous Flow Pump**Choon-Sik Jhun, PhD - Penn State Univ

1:30pm - 3:00pmBIOENGINEERING INVITED SPEAKERS 3Room: Holiday Ballroom 2 - Level 2Moderators: Christopher Siedlecki, PhD & Luke Herbertson, PhD

1:30pm - 2:00pmMicrotechnology - DevicesRobert Keynton, PhD - Prof & Chair Bioeng, Univ of Louisville

2:00pm - 2:30pmSurface Coatings – Interface Between Biological Tissueand DevicesMichael Danilich, PhD - Dir Biomedical Technologies, LunaInnovations Inc


3:45pm - 5:15pmBIOENGINEERING SLIDE SESSION 4Artificial Organ Development

Room: Holiday Ballroom 1 - Level 2Moderators: Amy Throckmorton, PhD & Scott Merz, PhD

3:45pm Development of a Cell Pouch To Form anArtificial PancreasDavid White, PhD - Univ of Western Ontario

4:00pm Bioengineered Skin Allografts - A New MethodTo Prevent Humoral ResponseLauren Brasile, PhD - Breonics

4:15pm Fibronectin Influences StaphylococcusEpidemidis RP62A Adhesion and Interactionwith Platelets on Polyurethane BiomaterialSurfaces**Christopher Siedlecki, PhD - Penn State Univ

4:30pm Evaluation of Small Intestine SubmucosaVascular Grafts for Small-Diameter VeinsReplacement: Methodology and Early Resultsin an Animal ModelLina Maria Quijano - Univ of Los Andes

4:45pm Platelet Inhibition by Antibiotics andImplications in Circulatory Support DeviceDevelopment**Denise Medvid - Penn State Univ

5:00pm Nitric Oxide (NO) Generating Silicone Hollow FibersKagya Amoako, MS - Univ of Michigan

3:45pm - 4:45pmBIOENGINEERING INVITED SPEAKERS 4Room: Holiday Ballroom 2 - Level 2Moderators: John Marks, PhD & Connie Hall, PhD

3:45pm - 4:15pmArtificial Bladder - Neo-OrgansTamer Aboushwareb, MD, PhD - Research Instructor, Wake Forest Univ

4:15pm - 4:45pmCreating a New Cardiovascular Bioengineering Institutein Turkey**Kamuran Kadipasaoglu, PhD - Instructor Mech Eng, Bahcesehir Univ

**Taha Elibol, BS - Research Assistant, Bahcesehir Univ

8:00am - 5:00pmBIOENGINEERING POSTER SESSION 2Pediatric & Adult Blood Pump Development

Posters Available All DayRoom: Exhibit Area - Key Ballroom 6 - Level 2

Board #

103 In-Vitro Hemodynamic Evaluation ofVentricular Suction Conditions of the EvaheartAssist Pump**Antonio Ferreira, PhD - Carnegie Mellon Univ

104 Differences in Hydrodynamic Performance and Flow Estimation between Axial andCentrifugal LVAD**Guruprasad Giridharan, PhD - Univ of Louisville

105 Introductory Tests to In Vivo Evaluation:Magnetic Coupling Influence in MotorControllerEduardo Bock, MSc - IDPC / FEM

106 Auxiliary Artificial Heart Endurance Test with aMock Circulation Loop SystemAron Andrade, MD - Inst Dante Pazzanese of Cardiology

107 Modeling and Diagnostics of Total Artificial HeartTaoufik Wassar - Univ of Houston

108 Surveillance and Management of HeartMate IIPercutaneous Drivelines**Trevor Snyder, PhD - Integris Baptist Medical Ctr

109 Evaluation of Oxygen Exchange in Total LiquidVentilation with a Bubble Gas Exchanger**Philippe Micheau, PhD - Univ de Sherbrooke

110 Aortic Outlet Extension in the 12cc Penn StatePediatric Ventricular Assist Device**Michael Fickes, BS - Penn State Univ

111 A Methodology To Study the Hemodynamics inPatients with Bi-Directional Glenn ShuntCarolina Vallecilla, MSc - Univ of Los Andes

112 A Fontan-Type Mock Circuit with HeterometricAutoregulation**Taha Elibol, BS - Bahcesehir Univ

113 Computational Assessment of Twisted CageFilaments for an Intravascular Axial FlowBlood Pump for Cavopulmonary Assistance**Amy Throckmorton, PhD - Virginia Commonwealth Univ

114 A Flow Analysis of a Polymeric Trileaflet Heart Valve**Dylan Frank, BS - Penn State Univ

115 The Scaling Effects in Comparing Pediatric andAdult Mechanical Heart Valves**Stephen Topper - Penn State Univ

116 Functionalization of Polymeric Membranes forTissue Engineering of Heart Valves**Ismar Cestari, MD, PhD - Univ of Sao Paulo

117 Development of a Novel Material TestingMethod for Simulation of Biomedical Materials**Tim Kaufmann, Dipl Phys - RWTH Aachen Univ

118 Development of a 2nd Gen. Data AcquisitionPlatform for the Pediaflow VAD**Salim Olia, BS - Univ of Pittsburgh

1:30pm - 4:15pmNEURAL SESSIONRoom: Carroll A, B - Level 3Moderators: Nicholas Hatsopoulos, PhD & Sonna Patel-Raman, PhD

1:30pm - 2:30pmNeuromorphic Engineering - Artificial Neural Systems,Such As Vision Systems, Head-Eye Systems, AuditoryProcessors & Autonomous RobotsTimothy Horiuchi, PhD - Assoc Prof Computer Eng, Univ of Maryland

John Pezaris, PhD - Asst Prof Neuroscience, Massachusetts General Hospital

Phil Troyk, PhD - Assoc Prof Bioeng, IIT

2:30pm - 3:00pmAdvances In Artificial HearingChristof Stieger, PhD - Asst Prof ENT Head & Neck Surg, Univ of Bern


3:45pm - 4:15pmArtificial EyesRobert Greenberg, MD, PhD - President & CEO, Second Sight MedicalProducts Inc

1:30pm - 4:15pmPEDIATRIC SESSIONRoom: Paca A, B - Level 3Moderators: Brian Duncan, MD, MBA & Timothy Baldwin, PhD

1:30pm - 1:45pmAn Overview of the NHLBI's PumpKIN Program**Timothy Baldwin, PhD - Prog Dir NHLBI, NIH


What Are the Best Methods for Anticoagulating PediatricPatients with MCS Devices? Christopher Almond, MD - Cardiologist, Children's Hosp Boston

Patricia Massicotte, MD - Dir Vascular Patency, Univ of Alberta

Holger Buchholz, MD - VAD Specialist, Univ of Alberta

**Peter Wearden, MD, PhD - Asst Prof Pediatrics CT Surg, Children'sHospital of Pittsburgh

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AY 293:00pm - 3:45pmVISIT EXHIBITS & POSTERS - ENJOY REFRESHMENTSExhibit Area: Key Ballroom 6 - Level 2

3:45pm - 4:15pmChallenges In Pediatric Cardiac Assist DeviceDevelopment & Use**James Antaki, PhD - Prof Biomed Eng, Carnegie Mellon Univ

5:30pm - 6:00pmASAIO MEMBER BUSINESS MEETINGRoom: Carroll A, B - Level 3

SATURDAY, MAY 298:00am - 8:30amRAPID FIRE FLASH PRESENTATIONS

Complicated Endocarditis Requiring TemporaryCirculatory Support after Surgical Correction - Incidenceand OutcomeChristian Binner, MD - Heart Center Leipzig

Pre-Clinical Assessment of the 3rd PediaFlow™ PediatricVentricular Assist Device Prototype**Timothy Maul, PhD - Univ of Pittsburgh

Delivering Physiologic Pulse Pressures with ContinuousFlow Ventricular Assist Devices**Mickey Ising - Univ of LouisvilleASAIO Young Innovator First Time Author Fellowship Recipient

Assessing Shear-Induced Platelet Activation: In VitroComparison between Human and Bovine BloodQijin Lu, PhD - FDA

Coating Polymers with a Human Extracellular Matrix(hECM) Significantly Improves Implant BiocompatibilityEmmett Pinney - Histogen Inc

8:30am - 12:00pmGENERAL SESSION 3 - SATURDAYRoom: Key Ballroom 8, 11, 12 - Level 2Chairmen: William Wagner, PhD & David Humes, MD

"Roadmap to Innovation: From Concept toCommercialization"

8:30am - 9:00amNovel Tools and Techniques to Facilitate Off-Pump LVADImplantation**William Cohn, MD - CV Surgeon, Texas Heart Institute

9:00am - 10:30amNEW VENTURE FORUM

Bridging Innovative Medical Concepts and Technologiesto a Commercial RealityPanel:

**Brian Duncan, MD, MBA

**Eric Chen, MS

**Thomas Meese, BSE

Tracy Warren

Edward Berger, PhD

Dynamitral: The Only Dynamic Mitral Valve Bioprosthesis**Arash Kheradvar, MD, PhD - Asst Prof Mech Eng, Univ of South Carolina

Occlude SolutionsCarolina Vallecilla, MSc - Univ of Los Andes

BloodoxCamila Castro, MSc - Univ de Los Andes


11:00am - 11:30amThe Sorcerer's Apprentice - An Inventor's Journey**Richard Wampler, MD - Consultant

11:30am - 12:00pmDEBATE

Ethics of Organ Resuscitation with Donors after Cardiac Death**Joseph Zwischenberger, MD - Chair Surgery, Univ of Kentucky

**Jeffrey Punch, MD - Chief Transplantation, Univ of MichiganMedical Center

1:00pm - 3:00pmCOMMERCIALIZATION SESSIONRoom: Key Ballroom 10 - Level 2Moderator: Tracy Warren


Commercializing Medical DevicesPanel Discussion - The Basics of Commercialization

Intellectual Property PrimerBonnie McLeod, PhD, JD - Partner / Attorney, Cooley GodwardKronish LLP

The Medical Device Development Pathway: From Conceptto Reimbursement in Seven Easy Steps**Brian Duncan, MD, MBA - Venture Partner - Arboretum Ventures

Equity Primer - The Play Book of VC'sTracy Warren - General Partner, Battelle Ventures LP

2:30pm - 2:45pmSmall Business: Trials and TribulationsDoug Godshall - President & CEO, HeartWare Inc

2:45pm - 3:00pmHow to Reach High Standards to Sell Your Laboratory? Awin-win Situation for Industry and Academia!**Egemen Tuzun, MD - Asst Dir CV Surg, Texas Heart Inst


1:00pm - 2:30pmCARDIAC SLIDE SESSION 5VADs

Room: Key Ballroom 9 - Level 2Moderators: Wayne Richenbacher, MD & Mark Macedo, BSN

1:00pm Characterization of Reasons for Turning downReferrals for Left Ventricular Assist Devices(LVADs)**Ian Ledford - Intermountain Medical Ctr

1:15pm Anatomic Fit of a Percutaneous VAD forTreatment of Acute Right Heart Failure**Scott Corbett, PhD - Abiomed Inc

1:30pm Ischemic Bowel Disease in Patients onMechanical Assist DevicesMonica Gustafson, MD - Univ of Arizona

1:45pm An Innovative, Miniaturized, Continuous-FlowTotal Artificial Heart: Device Design andPreliminary Studies**Mark Slaughter, MD - Univ of Louisville

2:00pm Anticoagulation Strategies for High RiskHeartMate II Patients**Walter Dembitsky, MD - Sharp Memorial Hospital

2:15pm Arteriovenous Malformation andGastrointestinal Bleeding in Patients with theHeartMate II Left Ventricular Assist DeviceZumrut Demirozu - Texas Heart Inst


Posters Available Until 12 Noon

Board #

119 A Single-Pass Orifice System To Assess RedBlood Cell Fragility**Luke Herbertson, PhD - FDA

120 Complicated Endocarditis Requiring TemporaryCirculatory Support after Surgical Correction -Incidence and OutcomeChristian Binner, MD - Heart Center Leipzig

121 Pre-Clinical Assessment of the 3rd PediaFlow™Pediatric Ventricular Assist Device Prototype**Timothy Maul, PhD - Univ of Pittsburgh

122 A New Failing Fontan Sheep Model**Dongfang Wang, MD, PhD - Univ of Kentucky

123 Left Ventricular Reverse Remodeling with theHeartMate II LVAD as Measured by LeftVentricular End Diastolic Dimensions andSeverity of Mitral Regurgitation**Jeffrey Morgan, MD - Henry Ford Hospital

124 Quantification of Ambulatory Power Source forVentricular Assist SystemCraig Carder, MSEE - HeartWare Inc

125 In-Vitro Optimization of Inflation/DeflationControl for Para-Aortic Counter-PulsatileCirculation SupportMing-Yao Chan, PhD - Nat'l Cheng Kung Univ

126 A New Axial Blood Designed for Adults inFuwai Hospital**Yan Zhang, MD - Fu Wai Hospital

127 Heart Rate Variability in Ventricular AssistDevice Animals in View of the MathematicalModels**Eiki Akagawa, PhD - Nat'l Cardiovascular Research Ctr

128 Regional Cerebral Oxygen SaturationMonitoring during Unilateral and BilateralCarotid Perfusion for Cerebral Protection inAortic SurgeryPasquale Totaro, MD, PhD - IRCCS Foundation S Matteo

129 Acquisition of Accurate Pressure-Volume Loopsof Left Ventricle in Mock CirculationYoshihiro Miyazawa - Tokyo Denki Univ

130 Experimental Evaluation of the Incor PediatricVentricular Assist Device**Idagene Cestari, PhD - Heart Inst, InCor

131 Clinical Experience with Terumo-Triplex inTotal Arch Replacement-Analysis ofPostoperative Serum Leakage, Graft DilatationRatio and Inflammatory Response**Toshihiro Ohata, MD, PhD - KKR Sapporo Medical Ctr

132 Hydraulic Ventricular Work Reduction with theMicromed cf-LVAD, an Ex-Vivo StudyKim Pennings, BSc - Eindhoven Univ of Technology

133 Interlaboratory Measurements of FlowParameters for Comparison to CFD Simulationsof FDA's Nozzle ModelPrasanna Hariharan - FDA

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under Counter-Pulsatile Circulation SupportChun-Hao Hung - Aeronautics & Astronautics

135 Computational Fluid Dynamic Analysis ofAerosol Distribution in the Human Tracheo-Bronchial Tree**Paola Bagnoli, PhD - Politecnico di Milano

136 A Computational Approach To Assess the Effectof Dynamic Annulus on Mitral's Leaflet StressDistribution**Ahmad Falahatpisheh, MSc - Univ of South Carolina

137 Investigation of Steady Flow through aRealistic Model of the Thoracic Human AortaUsing 3D Stereo-PIV and CFD-Simulation**Tim Kaufmann, Dipl Phys - RWTH Aachen Univ

138 New Computational Method in Tensor-BasedHemolysis Analysis for Artificial Heart Pump**Jaewook Nam, PhD - Rice Univ

139 Flow Rate Estimation for a Pneumatic ArtificialHeart Using the Driveline Air Mass Flow**Kentaro Ohnuma, PhD - Nat'l Cardiovascular Research Ctr

140 Hemodynamic Analysis of a Novel SphericalPositive Displacement Rotary Blood Pump**Greg Burgreen, PhD - Optimal LLC

141 A Novel Ex Vivo Perfusion System for Analysisof High Blood Pressure in Human VesselsUlrich Schreiber, PhD - German Heart Ctr Munich

142 Influence of Hemocor HPH-Hemoconcentratoron ATP Release from Human Erythrocytes**Jan-Stanley Simoni, DVM, PhD - Texas Tech Univ

143 Bridge to Recovery with a ThoratecBiventricular Assist Device for PostpartumCardiomyopathy: A Case Report**Hannah Zimmerman, MD - Univ of Arizona

144 Evaluation of Less Invasive Treatment forAortic Aneurysm with Ischemic Heart Diseaseby Catheter InterventionShigeki Ito, MD, PhD - Nishitokyo Central General Hospital

145 Nitinol Based Artificial Muscle IndependentBiventricular External Cardiac Assist Device:Bench Test ResultsAlexandre Michalis, MD - CHUV

146 PIV and Wall-PIV Study of a ValvelessCounterpulsation Heart Assist Device**Leonid Goubergrits, PhD - Charite Universitaetsmedizin Berlin

147 Rare Cardiac Pathology: Unilateral Absence ofPulmonary Artery with Tetralogy of FallotTijen Alkan-Bozkaya, MD - Istanbul Bilim Univ

148 Tacrolimus Once-Daily Formulation in the De-Novo Prophylaxis of Transplant Rejection inHeart Allograft RecipientsAkhim Koch - Uniklinik Heidelberg


1:30pm - 2:30pmPULMONARY SLIDE SESSION 4Room: Key Ballroom 7 - Level 2Moderators: Richard Chan, CCP & Zhongjun Wu, PhD

1:00pm Platelet Response to ExtracorporealRespiratory Support**Xiaoqin Zhou, MD - Univ of Kentucky

1:15pm Combined Pulmonary and Renal Support in OneExtracorporeal Device**Bettina Wiegmann, MD - Hannover Medical School

1:30pm Evaluation of Platelet Activation in OvinesImplanted with Integrated Pump-Lung UsingSoluble P-SelectinKang Zhou, MD - Univ of Maryland

1:45pm Pulsatile Versus Non Pulsatile Blood Flow inBlood Oxygenators: A CFD StudyMarcus Hormes - RWTH Aachen Univ

2:00pm CFD Analysis of a Percutaneous RespiratoryAssist Catheter**Greg Burgreen - Optimal LLC

2:15pm Immobilized Carbonic Anhydrase on HollowFibers Accelerates CO2 Removal from Blood**David Arazawa - Univ of Pittsburgh


1:00pm - 2:30pmBIOENGINEERING SLIDE SESSION 5Room: Holiday Ballroom 1 - Level 2Moderators: Karen May-Newman, PhD & Breigh Roszelle, MS

1:00pm Compliant Thoracic Artificial Lung DesignUsing Fluid-Structure Interaction Modeling**Rebecca Schewe, MS - Univ of Michigan

1:15pm Robust Simulation of CFD-Predicted Hemolysis**Greg Burgreen, PhD - Optimal LLC

1:30pm Numerical Model of Thrombosis andThromboembolization: Microfluid Effects**Kenneth Solen, PhD - Brigham Young Univ

1:45pm An Improved Experimental Wall ShearEstimation within a 50cc Penn State Blood Pump**Jason Nanna, BS - Penn State Univ

2:00pm Numerical and Experimental Investigation ofthe Flow through the LVAD Outlet Conduit-Aorta Anastomosis**Esra Sorguven, PhD - Yeditepe Univ

2:15pm Flow Patterns of the LVAD-Assisted LeftVentricle Studied in a Mock Circulatory Loop**Karen May-Newman, PhD - San Diego State Univ

8:00am - 12:00pmBIOENGINEERING POSTER SESSION 3Models & Surfaces to Improve Artificial Organs

Room: Exhibit Area - Key Ballroom 6 - Level 2

Posters Available Until 12 Noon

Board #

149 Delivering Physiologic Pulse Pressures withContinuous Flow Ventricular Assist Devices**Mickey Ising - Univ of Louisville

150 Blood Dispersion in Capillaries**David Macku, MD, MSc - Czech Technical Univ

151 Assessing Shear-Induced Platelet Activation:In Vitro Comparison between Human andBovine BloodQijin Lu, PhD - FDA

152 Design of a New Mag-Lev Hemolyzer Using CFD**Zhongjun Wu, PhD - Univ of Maryland

153 Analysis of Pulsatile Flow in a Quasi-Angiostenosis Model Using the Finite ElementMethodNaoki Katsura, MS - Toin Univ of Yokohama

154 Pressure Versus Volume Loop Assessment for aPhysical Cardiovascular Simulator SystemJeison Fonseca, MSc - Institute Dante Pazzanese ofCardiology

155 3-D Reconstructed Patient-SpecificCavopulmonary Connection with MechanicalAssistance in the Inferior Vena Cava**Sonya Bhavsar, BS - Virginia Commonwealth Univ

156 Chitosan/Gelatin Modified Film for Use inPrevention of Postoperative PeritonealAdhesionsElyas Shamram, MSc - Iran Univ

157 Coating Polymers with a Human ExtracellularMatrix (hECM) Significantly Improves ImplantBiocompatibilityEmmett Pinney - Histogen Inc

158 Construction of a System for Analysis of CellPopulation Behavior on a Fibrous Scaffold**Hiroo Noguchi, MS - Tokyo Denki Univ

159 Platelet Adhesion to Polyurethane Urea underCardiac Impulse**Katherine Chorpenning, MS - Penn State Univ

160 Fibrinogen Bioactivity and Platelet Adhesionon Biomaterial Surfaces**Christopher Siedlecki, PhD - Penn State Univ

161 Contact Activation of Blood Coagulation byMixed Thiol Self-Assembled MonolayersJames Bauer - Penn State Univ

162 Evaluation of Cell Proliferation Potential on aFibrous Scaffold Structure**Kazuhiro Nonaka, MS - Tokyo Denki Univ

163 Simulation of Breathing Effects and MovementArtifacts in Mock Circuits**Heinrich Schima, PhD - Medical Univ of Vienna

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