antoine harfouche, ph.d. associate professor of forest ... · antoine harfouche, ph.d. associate...
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Antoine Harfouche, Ph.D.
Associate Professor of Forest Biotechnology
Brain Gain Program, Ministry of Research,
DIBAF, University of Tuscia, Italy
Empowering the young: innovative entrepreneurship foryoung experts in biotechnology
7-9 November 2016 - Popilia Resort, Calabria, Italy
TREE IMPROVEMENTPROGRAM
INNOVATIVE FOREST BIOTECHNOLOGIESBRIDGING GENOMICS WITH PHENOMICS: THE SOLUTION
Harfouche et al., manuscript submitted
24-25%Lignin
22-23%
Hemi-cellulose
37-39%Cellulose
Bioproducts MarketsProcessing Routes
Chemical/biochemical
(fermentation, anaerobic
digestion)
Thermochemical
(gasification, pyrolysis,
depolymerisation)
Biomass Production and Handling
Biomass
Pre-treatmentHybrid
Pro
duct
s R
ecov
ery
Biochemicals and Biomaterials
BiofuelsLignin
CelluloseHemicellulose
Energy
Energy
C O U P L I N G F O R E S T & I N D U S T R I A L B I OT E C H N O LO GY: D E V E LO P I N G 2 N D G E N E R AT I O N B I O F U E L S A N D B I O - B A S E D
M AT E R I A L S T H AT D O N OT C O M P E T E W I T H F O O D C R O P S
Harfouche et al. (2014). Annals of Silvicultural Research 38: 42-50.
PRESCRIPTIONS FOR THE CREATION OF ENTREPRENEURIAL ECOSYSTEM
Entrepreneurial ecosystem Mazzarol 2014
WHY IT IS IMPERATIVE TO TEACH ENTREPRENEURSHIP
• Our education system is responsible for preparing young people to build successful lives.
• They should be ready for the wide range of possibilities ahead of them, including working for others, starting their own ventures, and contributing to their communities.
• All of these options require a depth of knowledge as well as creative problem solving skills, leadership abilities, experience working on effective teams, and adaptability in an ever-changing environment.
• It’s no coincidence that these are the same capabilities that employers say they want in college graduates.
• Entrepreneurship can be taught using similar scaffolding of skills, building upon our natural ability to imagine
© Tina Seelig | Stanford University
© Tina Seelig
© Tina Seelig
© Tina Seelig
© Tina Seelig
© Tina Seelig
We can confidently assert that these skills can be taught and mastered
• By some estimates, no more than 20% of Ph.D. life scientists landtenure-track faculty jobs within 6 years of earning their terminaldegrees.
• Yet, most graduate programs continue to groom graduate students andpostdocs for faculty jobs.
• Meanwhile, the market for industrial R&D jobs is declining
• The result is an employment market where companies can afford to bechoosy -- and companies have mostly stopped choosing scientistsstraight out of grad school or a postdoc.
• “Companies are no longer willing to hire Ph.D.s who don’t bringadditional skill sets to the table”
• “They tend to hire candidates who they think will add value to thecompany in addition to research skills.”
KEY DRIVING FORCES
Industry
Investors
Foundations
Small Business
University
Discovery Development Commercialization
Level of Development
Re
sou
rce
s In
vest
ed
Valley of Death
EC R
&I:
H2
02
0EC
Mar
ie S
kło
do
wsk
a-C
uri
e EC
ER
CSB
IREC
EA
CEA
MIU
RM
ISE
MIP
AA
FIN
NO
VA
LA
ZIO
PSR
Plant Translational Research
Filling Gaps
CREATING AN INNOVATION ECOSYSTEM THROUGH TRANSLATIONAL RESEARCH
NEW VENTURE CREATION PROCESS IN BIOTECH INDUSTRY
Big problem big opportunity
‘Good science’ultimately wins
Mehta (2004) Paths to entrepreneurship in life sciences. Nat Biotechnol 26:1331-1333
Company’s IP must be defensible and other patent cannot block the path to commercialization
There must be a clear business model/strategy for generating a significant profit.
Developed product must be viable
The company should target a large and or a rapidly growing market
Management should have the skills to implement the business plan
Scientist
Entrepreneur
Bioentrepreneur
People who often enjoy stretching their horizons by learning and experimenting with new ideas and skills
People who identify opportunity, assemble required resources, implement a practical action plan, and harvest the rewards in a timely flexible. way
Scientists as CEO for a technology-driven company
BIOENTREPRENEUR
=
THE IDEAL BIOENTREPRENEUR?
• You are charismatic individual who articulate plans well
• You are skillful manager
• You possess technical knowledge of the area
• You are energetic to the point being “driven”
• You possess the ability to lead
• You have an appropriate track record
Tell me and I forgetTeach me and I may rememberInvolve meand I learn
Business Canvas Model
TEAM WORK
NE
TW
O RK
I N G
Cultivating the Next Generation of Bioentrepreneurial Minds
New Learning & Teaching Model TM
Tech Transfer
INVENTION
CYCLE
© Tina Seelig
Success
UNLOCKING THE ENTREPRENEURIAL POTENTIAL OF BIOTECH INNOVATORS
CULTIVATING THE ENTREPRENEURIAL MINDSET AND BUSINESS SKILLSETS TO START UP NEW BIOTECH VENTURES
Inputs Outputs Outcomes - Impact
Activities Participation
What we do • Develop
Products, Curriculum,Resources
• Train • Provide
Counseling• Assess• Facilitate• Partner• Work with media
Who we reach
• Participants• Clients• Agencies• Decision-
makers• Customers
Medium term Long term
What the medium term results are
• Action• Behavior• Practice• Decision-
making• Policies• Social Action
What the ultimate impact(s) is(are)
• Conditions• Social• Economic• Civic• Environmental
Short term
What the short term results areChange in
• Learning• Awareness• Knowledge• Attitudes• Skills• Opinions• Aspirations• Motivations
Resources
What we have
• Motivation and capabilities
• R&D expenditure
• Budget and income
• Donations and grants
THE BIOINNO INPUT - IMPACT PROCESS
EDUCATE TO INNOVATEBIOINNO SUCCESSFULL B IOENTREPRENEURS
EMPOWERING EVERY EUROPEAN TO BECOME AN ENTREPRENEUR
ENTREPRENEURSHIP ACROSS AGROFORESTRY THROUGH CAPACITY BUILDING FOR YOUNG FARMERS
Dr Kai-Uwe
Schwarz
T H E WAT B I O - B I O I N N O E N T R E P R E N E U R S H I P T R A I N I N G :D E V E LO P I N G D R O U G H T - TO L E R A N T B I O M A S S C R O P S F O R E U R O P E
Knowledge
Alliances
Ministero Istruzione, Università e Ricerca
Education and
Culture
Lifelong Learning
Programme
ACKNOWLEGMENTS
Thank you
If forest biotech is to remain a wellspring of innovation, industry and academia need to do more to cultivate the next generation of entrepreneurial minds in forestry …