antihypertensive - group 8

8/10/2019 Antihypertensive - Group 8

1/10

Generic Name: Isosorbide Dinitrate

IUPAC Name: 1,4:3,6-dianhydro-D-glucitol 2,5-dinitrate

Stucture:

Brand

Names

Manufacturer Available

Dosage

Forms

Available

Dosage

Strength

Current Retail

Price

Clinical Indication/s Pregnan

Categor

Isordil Pfizer

Sublingual

Tablet

Tablet

5mg

10mg

100s

(P1892.41)

100s

(P1796.10)

Indicated for the

prevention of angina

pectoris due to

coronary artery

disease. Essential in

patients withcongestive heart

failure, acute

congestive heart

failure and chronic

congestive heart

failure.

C

Isoket GlaxoSmithKline

Tablet

5mg 50s(P517.90)

Treatment &


pectoris attacks.Maintenance therapy

after MI. Fresh MI w/

left ventricular failure.

Acute left ventricular

failure of other origins.

Long-term treatment

of chronic CHF. Chronic

C

10mg 50s(P645.90)

SR Tablet 20mg 50s(P677.60)


2/10

MR Tablet 40mg 50s(P947.60)

right ventricular

failure, chronic cor

pulmonale.

IV infusion 1mg/mL 10s(P5926.00)

Imdur AstraZeneca Tablet

30mg

100s

(P2317.00) Prophylactic treatment

of angina pectoris B

60mg 100s

(P3780.00)

Bideren Novopharm Tablet 10mg 100s

(P125.00)

Prophylactic treatment

of angina pectoris C

Dilatrate-

SR

Schwarz Pharma Capsule 40mg 100s

($16.00) US

Indicated for the


pectoris due to

coronary artery

disease

C

Generic: AmlodipineIUPAC: (RS)-3-ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate

Structure:


3/10

Brand

Names


Dosage

Forms

Available

Dosage

Strength

Current Retail

Price

Clinical

Indication/s

Pregnancy

Category

Aforbes Merck Tablet 5 mg 100's

(P826.58/box)

All Management

of HTN & for

prophylaxis of

angina. All Category

10 mg 100's

(P1288.02/box)

Vasalat Apotex Tablet 5 mg 100's

(P1215.00/pack)

10 mg 100's

(P2000.00/pack)

Lopicard Getz Pharma Tablet 5 mg 20's(P220.00/pack)

10 mg 20's

(P330.00/pack)

Cardivasc Cathay YSS Tablet 5 mg 100's

(P616.00/box)

10 mg 100's

(P1092.00/box)

Amvalat Pasteur Pharma Tablet 5 mg 100's

(P1100.00/box)

10 mg 100's

(P1600.00/box)


4/10


5/10

Tarka Abbott Tablet 180mg/2mg P1779.38/pack

(28's)

Treatment of essential

HTN in patients whos

BP has been

normalized w/ the

indivual components in

the same proportion ofdoses or whose BP is

not adequately

controlled on

tradolapril or

verapamil alone.

D

Isoptin/

Isoptin SR

Abbott Intravenous

Injection

5mg/2mL P859.88 ((amp)

5 x 1's)

Isoptin/Isoptin SR 180

Essential HTN, chronic

cornary insufficiency,

angina pectoris,paraxysmal

supraventricular

tachycardia,

tachyarrhthmias, long-

term treatment after

MI.

Isoptin SR 240

Essential HTN.

C

SustainedRelease

Tablets

240mg 6.68 (us)

180mg P3462.69/pack

(60's)

Tablet 80mg P2981.05/pack

(100's)

Sandoz

Verapamil

Sandoz Tablet 240mg P52.00 Control of

supraventriculararrythmias &

management of angina

pectoris & HTN.

C

Covera HS Pfizer Tablet 180mg 0.341/tab (us) Management of

Hypertension and

angina.

C

240mg 0.781/tab (us)


6/10

Antihypertensive

Generic Name: Propranolol

IUPAC Name: (2R)-1-naphthalen-1-yloxy-3-(propan-2-ylamino)propan-2-ol

Stucture:

Brand

Names


Dosage

Forms

Available

Dosage

Strength

Current Retail

Price

Clinical Indication/s Pregnan

Categor


7/10

Antrazine S.V. More

Pharma Corp.

Tablet 10mg Php28.98/tab Symptomatic relief of

allergic conditions

including rhinitis &

chronic urticaria.

Improves or relieves

the symptoms ofseasonal allergic

rhinitis (hay fever). It

also alleviates

rhinorrhea & sneezing,

though, less effective

for nasal congestion.

B

Texzine GX International

Inc.

Film-

coated

Tablet

10mg Php20.00/tab Used for the

symptomatic relief of

allergic conditions

including rhinitis and

chronic urticaria.

Alnix Westmont

Pharmaceuticals

Film-

coated

tablet

10mg Php23.77/tab Treatment of chronic

urticaria, pruritus,

allergic rhinitis, &

allergic conjunctivitis.

B

Oral

Drops

2.5mg/ml Php144.59/10m

l

Syrup 5mg/5ml Php127.04/30ml

Php242.70/60m

l

Aforvir Xeno

Pharmaceuticals

Phils

Syrup 5mg/ml Php184.00/

60ml

Symptomatic relief of

allergic conditions

including hay fever,

rhinitis & chronic

urticaria.

B

Tablet 10mg Php26.03/

tab

Virlix GlaxoSmithKline Tablet 10mg Php46.00/tab Treatment of perennial

& seasonal allergic

rhinitis, chronic

idiopathic urticaria &

allergic conjunctivitis.

B

Oral

Drops

10mg/mL Php391.00/

10ml

Oral

Solution

1mg/mL Php221.80/

30ml


8/10

Antihypertensive

1.

Generic Name: Losartan

IUPAC Name: 2-butyl-4-chloro-1-[p-(o-1H-tetrazol-5ylphenyl)benzyl]imidazole-5-methanol

Stucture:

Brand

Names


Dosage

Forms

Available

Dosage

Strength

Current

Retail

Price

Clinical indication Pregnancy

category

Cozaar Merck Sharp &

Dohme

Tablet 25mg $1.45 HTN. Reduction in the

risk of CV morbidity &

mortality in

hypertensive patients

w/ left ventricular

hypertrophy. Renal

protection in type 2

diabetic patients w/

proteinuria.

Category C;

Category D in

2nd& 3rd

trimester

50 mg $1.21

100mg $1.27

Getzar Getz Pharma Tablet 50mg 100s

(P1,250)

Management of HTN &

may have a role in

Category C;

Category D in


9/10

100mg 100s

(P2,100)

patients who develop

cough w/ ACE

inhibitors.

2nd& 3rd

trimester

Lifezar TheraPharma Tablet 50mg 50's

(P1162.60

/pack)

HTN. Reduction in the

risk of cardiovascular

morbidity and

mortality in patients

with left ventricular

hypertrophy.

Category C;

Category D in

2nd& 3rd

trimester

100mg 50's

(P1317.48

/pack)

Losacar Zydus Cadila Tablet 50mg P19.50/ta

b

Treatment of mild to

moderate HTN

Category C;

Category D in

2nd& 3rd

trimesterFilm-coated

tablet

100mg P17.00/fil

m-coated

tab

Management of HTN,

particularly in patients

who develop cough w/ACE inhibitors & to

reduce the risk of

stroke in patients w/

left ventricular

hypertrophy, & in the

treatment of diabetic

nephropathy. It has

also been tried in

heart failure & in MI.

Losagard InnoGen

Pharmaceuticals

Film-coated

tablet

50mg 30's

(P387.75/

pack)

Treatment &

management of HTN.

Category C;

Category D in

2nd& 3rd

trimester100mg 30's

(P727.50/

pack)


10/10

antihypertensive - group 8

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