anti cellulite and firmness · reduction of fat nodes d28 effect on skin surface fat nodes (yellow)...

6
BODY 3 COMPLEX™ 3-in-1 Body Skin Enhancer Unroasted shea butter and avocado seed extracts in bentonite - Triple action: reduces the appearance of cellulite and stretch marks and increases firmness Active ingredients

Upload: others

Post on 24-Jun-2020

1 views

Category:

Documents


0 download

TRANSCRIPT

Page 1: ANTI CELLULITE AND FIRMNESS · Reduction of fat nodes D28 Effect on skin surface Fat nodes (yellow) ANTI!CELLULITE AND FIRMNESS Test protocol - Applica tion by 22 women (mean age

BODY3 COMPLEX™

3-in-1 Body Skin Enhancer

Unroasted shea butter and avocado seed extracts in bentonite-Triple action: reduces the appearance of cellulite and stretch marks and increases firmness

Body3 Complex™ reduces the appearance of cellulite and the orange-peel look, improves firmness and reduces the look of stretch marks.

Features and benefitsProduct descriptionINCI NAMEBentonite (1) (and) Butyrospermum Parkii (Shea) Butter Extract (2) (and) Persea Gratissima (Avocado) Fruit Extract (3)

CAS1302-78-9 (1), 91080-23-8 (2), 8024-32-6 (3)

EINECS215-108-5 (1), 293-515-7 (2), 232-428-0 (3)

ECOCERT / COSMOS STATUSRegistered

APPEARANCEOff-white to gray powder

FORMULATION Use below 40°C. Introduce via a premix phase: 1 part of Body3 ComplexTM for 5 to 7 parts of water.

DOSAGE - Preventive care: 0.1-0.5%- Treatment care: 0.5-1%

OPTIMUM pH < 9

APPLICATIONS- Slimming and reshaping products- Anti-cellulite products- Firming products- Anti-stretch mark products- Post-pregnancy treatment- Stomach-specific care- Anti-love handle treatment- Multifunctional body treatment

CHINA-COMPLIANT

FEATURES BENEFITS

Unique combination of 3 ingredients: unroasted shea butter extract, avocado seed extract incorporated in bentonite

Complete and multifunctional action

Roast-free shea butter processing method, preserving viminalol ester content

- Sustainable approach - Better slimming activity

3 levels of action (epidermis, dermis, hypodermis)

Triple action on cellulite, firmness and stretch marks

New lipolysis mechanism through ZAG modulation

Clinically proven results

Caffeine-like efficacy Slimming boosting effect

New mechanism for skin firmness via SKALP induction

Clinically proven results

Ultra-reshaping body3 gel-cream 12.237.09 C130

INGREDIENTS INCI NAME %

A Deionised Water Water 53.10

DermofeelTM PA-12* Sodium Phytate 0.20

Glycerin Glycerin 3.00

Granlux® AOX GL* Glycerin (and) Picea Excelsa Extract 1.00

EcogelTM Lysolecithin (and) Sclerotium Gum (and) Xanthan Gum (and) Pullulan

2.00

B Sweet Almond Oil Prunus Amygdalus Dulcis (Sweet Almond) Oil 5.00

Cetiol Sensoft Propylheptyl Caprylate 2.00

DermofeelTM G5DO* Polyglyceryl-5 Dioleate 1.00

C Body3 Complex™ Bentonite (and) Butyrospermum Parkii (Shea) Butter Extract (and) Persea Gratissima (Avocado) Fruit Extract

1.00

D Isocell™ Slim NC Caffeine (and) Sodium Salicylate (and) Lecithin (and) Silica

5.00

Deionised Water Water 20.00

E Aerosil 300 Silica 0.50

Sveltessence™ Glycerin (and) Water (and) Nephelium Longana Seed Extract

2.00

F Dermorganics™ 1388* Fragrance 4.00

G Bella Vita 3895 Fragrance 0.20

LUCAS MEYER COSMETICS S.A.S.

ZA les Belles Fontaines99 route de Versailles91160 Champlan - France T: +33 (0)1 69 10 69 69 - F: +33 (0)1 69 10 69 70

LUCAS MEYER COSMETICS CANADA INC.

Place de la Cité, Tour de la Cité2600 boul. Laurier, #900Québec (Québec) G1V 4W2 CanadaT: +1 418 653-6888 - F: +1 418 653-6005

This brochure is not intended for consumers and neither this brochure nor any extract thereof shall be used in order to commercialize products to consumers. No drawing, photograph or other extract derived from this brochure shall be used by any person without our prior written approval. As well, no claim with respect to the ingredient referred to in this brochure shall be made by any person without our prior written approval, even though the claim is set forth in this brochure. The person using the ingredient referred to in this brochure in the formulation of finished products is solely responsible for ensuring that the use made of the ingredient, the finished products marketed to consumers, their packaging, labelling and advertising materials and the claims made with respect to the finished products and the ingredient comply with all applicable laws and regulations. We hereby disclaim any warranty of suitability of the ingredient referred to in this brochure for any purpose. Any prospective user of the ingredient shall himself determine the suitability of the ingredient for his intended use and, as the case may be, obtain the required regulatory approvals for the commercialization of his finished products.

[email protected]

Litho

Can

ada

| 20

12-0

9 3

K

Roughness Up to -19%

Maximum amplitude Up to -24%

Volume Up to -38%

Reduction of fat nodes

D0 D28

Effect on skin surface

Fat nodes (yellow)

ANTI-CELLULITE AND FIRMNESSTest protocol

- Application by 22 women (mean age 57) 2x/day of a cream containing 1% Body3 Complex™ on one thigh versus a placebo on the other thigh for a period of 28 days;

- Evaluation of anti-cellulite effect on cutaneous surface using Primos 3D Pico®; - Evaluation of firmness effect using Dermascan® (ultrasound technique).

Anti-cellulite actionBody3 Complex™ smoothes the skin’s surface and fades the orange-peel look.

Firming action - Redensifying effectBody3 Complex™ decreases fat clusters, leading to dermis redensification.

D0 D28 D56

Cellulite appearance reduction

D0 D56

Firming action

D0 D56

Stretch marks and slimming action

Placebo

D0

D28

-3% (ns)

Fat clusters (black)

Body3 ComplexTM

D0

D28

Conjunctive tissue (yellow to green)

+9%*dermis density

* p<0.005

*Distributed in France by Lucas Meyer Cosmetics / Unipex Solutions France.

Maximum redensifying effect up to +16%

CUTANEOUS SURFACE EVALUATION

-12

-10

-8

-6

-4

-2

0

2

4

6

Vari

ati

on

(%

vs.

D0

)

VolumeMaximumamplitude

Roughness

∆ -7%*

∆ -13%** ∆ -13%**

-10% -9% -9%

-3%

4% 4%

* p<0.05 **p<0.01

Placebo Body3 ComplexTM 1%

Active ingredients

pH: 5.0 - 5.5 - Viscosity (Rheo ELV 8, spindle 4, 6 rpm, 3 mn): 20 000 - 35 000 mPa.s

Page 2: ANTI CELLULITE AND FIRMNESS · Reduction of fat nodes D28 Effect on skin surface Fat nodes (yellow) ANTI!CELLULITE AND FIRMNESS Test protocol - Applica tion by 22 women (mean age

ENHANCING SKIN FIRMNESS

Induction of SKALP production

Elastase is a serine protease involved in the degradation of dermis fibers. SKALP (SKin-

derived AntiLeukoProteinase) is an elastase inhibitor.

Test protocol

- Incubation of normal human keratinocytes for 48 hours with avocado seed extract;

- Quantification of total proteins by the Bradford method;

- Quantification of SKALP by the ELISA method.

Avocado seed extract stimulates the production of SKALP to limit dermis fiber degradation and fat infiltration.

REDUCING THE APPEARANCE OF STRETCH MARKSTest protocol

- 24 women (mean age: 26) with early striae (pink to red-purple);

- Application twice-daily of a bentonite base on a chosen stretch mark for 56 days;

- Morphological analysis of stretch marks on photographs at D0 and D56;

- Self-assessment by volunteers.

Body3 Complex™ is a unique cosmetic active complex whose triple-action formula aims at fighting the appearance of cellulite and stretch marks and increasing firmness.

BODY3 COMPLEX™: 3-IN-1 BODY SKIN ENHANCER Today’s savvy buyers of body care products expect aesthetics and performance in a single package. Multifunctionality is the key and that is why Lucas Meyer Cosmetics has developped Body3 Complex™, a unique cosmetic active complex which provides a triple-action benefit due to the synergistic combination of three ingredients.

3 INGREDIENTSUnroasted shea butter extract Unroasted shea butter extract is obtained through a sustainable process and is made by women in Burkina Faso villages. When manufactured without the traditional roasting phase, shea butter preserves its viminalol ester content and its slimming active properties.

Avocado seed extractAvocado seeds are by-products of the Burkina Faso food industry. Avocado seed extract is rich in unsaponifiable matter known to activate connective tissue metabolism.

Bentonite The avocado seed and unroasted shea butter extracts are entrapped in this multi-lamellar active clay, creating a powder-form ingredient that is easier to formulate. Bentonite provides biological benefits such as the regeneration of extra-cellular matrix proteins (ECM). The bentonite also provides a progressive-release delivery system.

FIGHTING CELLULITE VIA A NEW PATHWAY

ZAG ModulationZAG is a protein secreted by adipocytes and keratinocytes which is able to bind to the `-3 adregergic receptor to induce lipolysis.

Test protocol

- Incubation of normal human keratinocytes for 48 hours with shea butter (SB) extract;

- Quantification of the ZAG using the ELISA method.

Shea butter extract stimulates the synthesis of the ZAG with a dose-dependent effect on lipolysis activation.

Indirect lipolysis stimulation through ZAGTest protocol

- Incubation of normal human keratinocytes for 48 hours with shea butter (SB) extract; - Removal of subnatant placed in adipocyte culture for an additional 2 hours compared

to adipocytes incubated with caffeine;- Quantification of non-esterified fatty acids (NEFA) by spectrophotometry analysis.

Shea butter extract stimulates lipolysis through the ZAG pathway with a caffeine-like efficacy. The activity of the caffeine can be boosted by adding Body3 ComplexTM.

Direct lipolysis stimulation

Test protocol

- Incubation of normal human adipocytes for 2 hours with Body3 Complex™; - Quantification of non-esterified fatty acids (NEFA) by the ELISA method.

Body3 Complex™ stimulates lipolysis and free fatty acid release with a dose-dependent effect for an optimal action against cellulite.

D0 D5610

12

14

16

18-5%

a*

para

mete

r

EVOLUTION OF STRETCH MARK REDNESS

100%

91%

86%

86%

82%

77%

64%Stretch marks

are thinnerStretch marks are

less apparentStretch marksare less raised

The roughnessis attenuatedSkin is more

homogeneousStretch marks

are lighterSkin is softer

0 20 40 60 80 100Positive opinion

SELF-ASSESSMENT

COLOR VARIATION BETWEEN STRETCH MARKS AND NORMAL SKIN

D0 D562

4

6

8

-11%

Dif

fere

nce o

f co

lor

∆E

ZAG STIMULATION

SB extract 0.005%(Body3 Complex™

0.05%)

SB extract 0.01%(Body3 Complex™

0.1%)

0

10

20

30

40

50

60 +56%*

+15%ZA

G le

vel

(%

co

mp

are

d t

o c

on

tro

l)

* p<0.005

LIPOLYSIS STIMULATION

Caffeine 0.002% SB extract 0.001%(Body3 Complex™

0.01%)

0

20

40

60

80

+60%*+67%*

NE

FA

level

(%

co

mp

are

d t

o c

on

tro

l)

* p<0.05

Control Avocado extract 0.0006%(Body3 Complex™ 0.1%)

0

100

200

300

400

500

+25.4%*

SK

AL

P (

pg

/μg

pro

tein

)

SKALP PRODUCTION

* p<0.05

0.05% 0.1% 0.2%0

100

200

300

+102%*

NE

FA

level

(% c

om

pare

d t

o c

on

tro

l)

Body3 ComplexTM

+163%*

+256%*

LIPOLYSIS STIMULATION

* p<0.001

D0 D56

REDUCTION OF STRETCH MARK SURFACE

Bentonite visibly reduces stretch mark surface.

22% surface reduction

D0 D56

REDUCTION OF STRETCH MARK COLOR

Bentonite visibly attenuates stretch marks to progressively recover normal skin color.

3 ACTIONSReduction of the appearance of cellulite Cellulite is seen in 85% of women regardless of age, ethnic origin, body shape or weight. It is characterized by fat accumulation in adipocytes particularly on the thighs, buttocks, hips and stomach. Body3 Complex™ differentiates itself from other slimming agents by its unique ability to stimulate lipolysis by acting on the ZAG pathway.

Enhancement of firmnessWithout ECM fibers, adipocytes escape from the hypodermis and move toward the surface of the skin to form cellulite. Body3 Complex™ is able to stimulate SKALP (SKin-derived AntiLeukoProteinase), an elastase inhibitor, to inhibit elastase activity, thereby limiting dermis degradation leading to a reduction of fat infiltration.

Reduction of the appearance of stretch marksStudies have demonstrated that the silanols contained in bentonite are known to regenerate ECM proteins. The bentonite contained in Body3 Complex™ reduces the color, length and overall appearance of stretch marks.

SC

DEJ

Dermis

Hypodermis

Epidermis

NEW LIPOLYSIS MECHANISMCELLULITE

Page 3: ANTI CELLULITE AND FIRMNESS · Reduction of fat nodes D28 Effect on skin surface Fat nodes (yellow) ANTI!CELLULITE AND FIRMNESS Test protocol - Applica tion by 22 women (mean age

ENHANCING SKIN FIRMNESS

Induction of SKALP production

Elastase is a serine protease involved in the degradation of dermis fibers. SKALP (SKin-

derived AntiLeukoProteinase) is an elastase inhibitor.

Test protocol

- Incubation of normal human keratinocytes for 48 hours with avocado seed extract;

- Quantification of total proteins by the Bradford method;

- Quantification of SKALP by the ELISA method.

Avocado seed extract stimulates the production of SKALP to limit dermis fiber degradation and fat infiltration.

REDUCING THE APPEARANCE OF STRETCH MARKSTest protocol

- 24 women (mean age: 26) with early striae (pink to red-purple);

- Application twice-daily of a bentonite base on a chosen stretch mark for 56 days;

- Morphological analysis of stretch marks on photographs at D0 and D56;

- Self-assessment by volunteers.

Body3 Complex™ is a unique cosmetic active complex whose triple-action formula aims at fighting the appearance of cellulite and stretch marks and increasing firmness.

BODY3 COMPLEX™: 3-IN-1 BODY SKIN ENHANCER Today’s savvy buyers of body care products expect aesthetics and performance in a single package. Multifunctionality is the key and that is why Lucas Meyer Cosmetics has developped Body3 Complex™, a unique cosmetic active complex which provides a triple-action benefit due to the synergistic combination of three ingredients.

3 INGREDIENTSUnroasted shea butter extract Unroasted shea butter extract is obtained through a sustainable process and is made by women in Burkina Faso villages. When manufactured without the traditional roasting phase, shea butter preserves its viminalol ester content and its slimming active properties.

Avocado seed extractAvocado seeds are by-products of the Burkina Faso food industry. Avocado seed extract is rich in unsaponifiable matter known to activate connective tissue metabolism.

Bentonite The avocado seed and unroasted shea butter extracts are entrapped in this multi-lamellar active clay, creating a powder-form ingredient that is easier to formulate. Bentonite provides biological benefits such as the regeneration of extra-cellular matrix proteins (ECM). The bentonite also provides a progressive-release delivery system.

FIGHTING CELLULITE VIA A NEW PATHWAY

ZAG ModulationZAG is a protein secreted by adipocytes and keratinocytes which is able to bind to the `-3 adregergic receptor to induce lipolysis.

Test protocol

- Incubation of normal human keratinocytes for 48 hours with shea butter (SB) extract;

- Quantification of the ZAG using the ELISA method.

Shea butter extract stimulates the synthesis of the ZAG with a dose-dependent effect on lipolysis activation.

Indirect lipolysis stimulation through ZAGTest protocol

- Incubation of normal human keratinocytes for 48 hours with shea butter (SB) extract; - Removal of subnatant placed in adipocyte culture for an additional 2 hours compared

to adipocytes incubated with caffeine;- Quantification of non-esterified fatty acids (NEFA) by spectrophotometry analysis.

Shea butter extract stimulates lipolysis through the ZAG pathway with a caffeine-like efficacy. The activity of the caffeine can be boosted by adding Body3 ComplexTM.

Direct lipolysis stimulation

Test protocol

- Incubation of normal human adipocytes for 2 hours with Body3 Complex™; - Quantification of non-esterified fatty acids (NEFA) by the ELISA method.

Body3 Complex™ stimulates lipolysis and free fatty acid release with a dose-dependent effect for an optimal action against cellulite.

D0 D5610

12

14

16

18-5%

a*

para

mete

r

EVOLUTION OF STRETCH MARK REDNESS

100%

91%

86%

86%

82%

77%

64%Stretch marks

are thinnerStretch marks are

less apparentStretch marksare less raised

The roughnessis attenuatedSkin is more

homogeneousStretch marks

are lighterSkin is softer

0 20 40 60 80 100Positive opinion

SELF-ASSESSMENT

COLOR VARIATION BETWEEN STRETCH MARKS AND NORMAL SKIN

D0 D562

4

6

8

-11%

Dif

fere

nce o

f co

lor

∆E

ZAG STIMULATION

SB extract 0.005%(Body3 Complex™

0.05%)

SB extract 0.01%(Body3 Complex™

0.1%)

0

10

20

30

40

50

60 +56%*

+15%ZA

G le

vel

(%

co

mp

are

d t

o c

on

tro

l)

* p<0.005

LIPOLYSIS STIMULATION

Caffeine 0.002% SB extract 0.001%(Body3 Complex™

0.01%)

0

20

40

60

80

+60%*+67%*

NE

FA

level

(%

co

mp

are

d t

o c

on

tro

l)

* p<0.05

Control Avocado extract 0.0006%(Body3 Complex™ 0.1%)

0

100

200

300

400

500

+25.4%*

SK

AL

P (

pg

/μg

pro

tein

)

SKALP PRODUCTION

* p<0.05

0.05% 0.1% 0.2%0

100

200

300

+102%*

NE

FA

level

(% c

om

pare

d t

o c

on

tro

l)

Body3 ComplexTM

+163%*

+256%*

LIPOLYSIS STIMULATION

* p<0.001

D0 D56

REDUCTION OF STRETCH MARK SURFACE

Bentonite visibly reduces stretch mark surface.

22% surface reduction

D0 D56

REDUCTION OF STRETCH MARK COLOR

Bentonite visibly attenuates stretch marks to progressively recover normal skin color.

3 ACTIONSReduction of the appearance of cellulite Cellulite is seen in 85% of women regardless of age, ethnic origin, body shape or weight. It is characterized by fat accumulation in adipocytes particularly on the thighs, buttocks, hips and stomach. Body3 Complex™ differentiates itself from other slimming agents by its unique ability to stimulate lipolysis by acting on the ZAG pathway.

Enhancement of firmnessWithout ECM fibers, adipocytes escape from the hypodermis and move toward the surface of the skin to form cellulite. Body3 Complex™ is able to stimulate SKALP (SKin-derived AntiLeukoProteinase), an elastase inhibitor, to inhibit elastase activity, thereby limiting dermis degradation leading to a reduction of fat infiltration.

Reduction of the appearance of stretch marksStudies have demonstrated that the silanols contained in bentonite are known to regenerate ECM proteins. The bentonite contained in Body3 Complex™ reduces the color, length and overall appearance of stretch marks.

SC

DEJ

Dermis

Hypodermis

Epidermis

NEW LIPOLYSIS MECHANISMCELLULITE

Page 4: ANTI CELLULITE AND FIRMNESS · Reduction of fat nodes D28 Effect on skin surface Fat nodes (yellow) ANTI!CELLULITE AND FIRMNESS Test protocol - Applica tion by 22 women (mean age

ENHANCING SKIN FIRMNESS

Induction of SKALP production

Elastase is a serine protease involved in the degradation of dermis fibers. SKALP (SKin-

derived AntiLeukoProteinase) is an elastase inhibitor.

Test protocol

- Incubation of normal human keratinocytes for 48 hours with avocado seed extract;

- Quantification of total proteins by the Bradford method;

- Quantification of SKALP by the ELISA method.

Avocado seed extract stimulates the production of SKALP to limit dermis fiber degradation and fat infiltration.

REDUCING THE APPEARANCE OF STRETCH MARKSTest protocol

- 24 women (mean age: 26) with early striae (pink to red-purple);

- Application twice-daily of a bentonite base on a chosen stretch mark for 56 days;

- Morphological analysis of stretch marks on photographs at D0 and D56;

- Self-assessment by volunteers.

Body3 Complex™ is a unique cosmetic active complex whose triple-action formula aims at fighting the appearance of cellulite and stretch marks and increasing firmness.

BODY3 COMPLEX™: 3-IN-1 BODY SKIN ENHANCER Today’s savvy buyers of body care products expect aesthetics and performance in a single package. Multifunctionality is the key and that is why Lucas Meyer Cosmetics has developped Body3 Complex™, a unique cosmetic active complex which provides a triple-action benefit due to the synergistic combination of three ingredients.

3 INGREDIENTSUnroasted shea butter extract Unroasted shea butter extract is obtained through a sustainable process and is made by women in Burkina Faso villages. When manufactured without the traditional roasting phase, shea butter preserves its viminalol ester content and its slimming active properties.

Avocado seed extractAvocado seeds are by-products of the Burkina Faso food industry. Avocado seed extract is rich in unsaponifiable matter known to activate connective tissue metabolism.

Bentonite The avocado seed and unroasted shea butter extracts are entrapped in this multi-lamellar active clay, creating a powder-form ingredient that is easier to formulate. Bentonite provides biological benefits such as the regeneration of extra-cellular matrix proteins (ECM). The bentonite also provides a progressive-release delivery system.

FIGHTING CELLULITE VIA A NEW PATHWAY

ZAG ModulationZAG is a protein secreted by adipocytes and keratinocytes which is able to bind to the `-3 adregergic receptor to induce lipolysis.

Test protocol

- Incubation of normal human keratinocytes for 48 hours with shea butter (SB) extract;

- Quantification of the ZAG using the ELISA method.

Shea butter extract stimulates the synthesis of the ZAG with a dose-dependent effect on lipolysis activation.

Indirect lipolysis stimulation through ZAGTest protocol

- Incubation of normal human keratinocytes for 48 hours with shea butter (SB) extract; - Removal of subnatant placed in adipocyte culture for an additional 2 hours compared

to adipocytes incubated with caffeine;- Quantification of non-esterified fatty acids (NEFA) by spectrophotometry analysis.

Shea butter extract stimulates lipolysis through the ZAG pathway with a caffeine-like efficacy. The activity of the caffeine can be boosted by adding Body3 ComplexTM.

Direct lipolysis stimulation

Test protocol

- Incubation of normal human adipocytes for 2 hours with Body3 Complex™; - Quantification of non-esterified fatty acids (NEFA) by the ELISA method.

Body3 Complex™ stimulates lipolysis and free fatty acid release with a dose-dependent effect for an optimal action against cellulite.

D0 D5610

12

14

16

18-5%

a*

para

mete

r

EVOLUTION OF STRETCH MARK REDNESS

100%

91%

86%

86%

82%

77%

64%Stretch marks

are thinnerStretch marks are

less apparentStretch marksare less raised

The roughnessis attenuatedSkin is more

homogeneousStretch marks

are lighterSkin is softer

0 20 40 60 80 100Positive opinion

SELF-ASSESSMENT

COLOR VARIATION BETWEEN STRETCH MARKS AND NORMAL SKIN

D0 D562

4

6

8

-11%

Dif

fere

nce o

f co

lor

∆E

ZAG STIMULATION

SB extract 0.005%(Body3 Complex™

0.05%)

SB extract 0.01%(Body3 Complex™

0.1%)

0

10

20

30

40

50

60 +56%*

+15%ZA

G le

vel

(%

co

mp

are

d t

o c

on

tro

l)

* p<0.005

LIPOLYSIS STIMULATION

Caffeine 0.002% SB extract 0.001%(Body3 Complex™

0.01%)

0

20

40

60

80

+60%*+67%*

NE

FA

level

(%

co

mp

are

d t

o c

on

tro

l)

* p<0.05

Control Avocado extract 0.0006%(Body3 Complex™ 0.1%)

0

100

200

300

400

500

+25.4%*

SK

AL

P (

pg

/μg

pro

tein

)

SKALP PRODUCTION

* p<0.05

0.05% 0.1% 0.2%0

100

200

300

+102%*

NE

FA

level

(% c

om

pare

d t

o c

on

tro

l)

Body3 ComplexTM

+163%*

+256%*

LIPOLYSIS STIMULATION

* p<0.001

D0 D56

REDUCTION OF STRETCH MARK SURFACE

Bentonite visibly reduces stretch mark surface.

22% surface reduction

D0 D56

REDUCTION OF STRETCH MARK COLOR

Bentonite visibly attenuates stretch marks to progressively recover normal skin color.

3 ACTIONSReduction of the appearance of cellulite Cellulite is seen in 85% of women regardless of age, ethnic origin, body shape or weight. It is characterized by fat accumulation in adipocytes particularly on the thighs, buttocks, hips and stomach. Body3 Complex™ differentiates itself from other slimming agents by its unique ability to stimulate lipolysis by acting on the ZAG pathway.

Enhancement of firmnessWithout ECM fibers, adipocytes escape from the hypodermis and move toward the surface of the skin to form cellulite. Body3 Complex™ is able to stimulate SKALP (SKin-derived AntiLeukoProteinase), an elastase inhibitor, to inhibit elastase activity, thereby limiting dermis degradation leading to a reduction of fat infiltration.

Reduction of the appearance of stretch marksStudies have demonstrated that the silanols contained in bentonite are known to regenerate ECM proteins. The bentonite contained in Body3 Complex™ reduces the color, length and overall appearance of stretch marks.

SC

DEJ

Dermis

Hypodermis

Epidermis

NEW LIPOLYSIS MECHANISMCELLULITE

Page 5: ANTI CELLULITE AND FIRMNESS · Reduction of fat nodes D28 Effect on skin surface Fat nodes (yellow) ANTI!CELLULITE AND FIRMNESS Test protocol - Applica tion by 22 women (mean age

BODY3 COMPLEX™

3-in-1 Body Skin Enhancer

Unroasted shea butter and avocado seed extracts in bentonite-Triple action: reduces the appearance of cellulite and stretch marks and increases firmness

Body3 Complex™ reduces the appearance of cellulite and the orange-peel look, improves firmness and reduces the look of stretch marks.

Features and benefitsProduct descriptionINCI NAMEBentonite (1) (and) Butyrospermum Parkii (Shea) Butter Extract (2) (and) Persea Gratissima (Avocado) Fruit Extract (3)

CAS1302-78-9 (1), 91080-23-8 (2), 8024-32-6 (3)

EINECS215-108-5 (1), 293-515-7 (2), 232-428-0 (3)

ECOCERT / COSMOS STATUSRegistered

APPEARANCEOff-white to gray powder

FORMULATION Use below 40°C. Introduce via a premix phase: 1 part of Body3 ComplexTM for 5 to 7 parts of water.

DOSAGE - Preventive care: 0.1-0.5%- Treatment care: 0.5-1%

OPTIMUM pH < 9

APPLICATIONS- Slimming and reshaping products- Anti-cellulite products- Firming products- Anti-stretch mark products- Post-pregnancy treatment- Stomach-specific care- Anti-love handle treatment- Multifunctional body treatment

CHINA-COMPLIANT

FEATURES BENEFITS

Unique combination of 3 ingredients: unroasted shea butter extract, avocado seed extract incorporated in bentonite

Complete and multifunctional action

Roast-free shea butter processing method, preserving viminalol ester content

- Sustainable approach - Better slimming activity

3 levels of action (epidermis, dermis, hypodermis)

Triple action on cellulite, firmness and stretch marks

New lipolysis mechanism through ZAG modulation

Clinically proven results

Caffeine-like efficacy Slimming boosting effect

New mechanism for skin firmness via SKALP induction

Clinically proven results

Ultra-reshaping body3 gel-cream 12.237.09 C130

INGREDIENTS INCI NAME %

A Deionised Water Water 53.10

DermofeelTM PA-12* Sodium Phytate 0.20

Glycerin Glycerin 3.00

Granlux® AOX GL* Glycerin (and) Picea Excelsa Extract 1.00

EcogelTM Lysolecithin (and) Sclerotium Gum (and) Xanthan Gum (and) Pullulan

2.00

B Sweet Almond Oil Prunus Amygdalus Dulcis (Sweet Almond) Oil 5.00

Cetiol Sensoft Propylheptyl Caprylate 2.00

DermofeelTM G5DO* Polyglyceryl-5 Dioleate 1.00

C Body3 Complex™ Bentonite (and) Butyrospermum Parkii (Shea) Butter Extract (and) Persea Gratissima (Avocado) Fruit Extract

1.00

D Isocell™ Slim NC Caffeine (and) Sodium Salicylate (and) Lecithin (and) Silica

5.00

Deionised Water Water 20.00

E Aerosil 300 Silica 0.50

Sveltessence™ Glycerin (and) Water (and) Nephelium Longana Seed Extract

2.00

F Dermorganics™ 1388* Fragrance 4.00

G Bella Vita 3895 Fragrance 0.20

LUCAS MEYER COSMETICS S.A.S.

ZA les Belles Fontaines99 route de Versailles91160 Champlan - France T: +33 (0)1 69 10 69 69 - F: +33 (0)1 69 10 69 70

LUCAS MEYER COSMETICS CANADA INC.

Place de la Cité, Tour de la Cité2600 boul. Laurier, #900Québec (Québec) G1V 4W2 CanadaT: +1 418 653-6888 - F: +1 418 653-6005

This brochure is not intended for consumers and neither this brochure nor any extract thereof shall be used in order to commercialize products to consumers. No drawing, photograph or other extract derived from this brochure shall be used by any person without our prior written approval. As well, no claim with respect to the ingredient referred to in this brochure shall be made by any person without our prior written approval, even though the claim is set forth in this brochure. The person using the ingredient referred to in this brochure in the formulation of finished products is solely responsible for ensuring that the use made of the ingredient, the finished products marketed to consumers, their packaging, labelling and advertising materials and the claims made with respect to the finished products and the ingredient comply with all applicable laws and regulations. We hereby disclaim any warranty of suitability of the ingredient referred to in this brochure for any purpose. Any prospective user of the ingredient shall himself determine the suitability of the ingredient for his intended use and, as the case may be, obtain the required regulatory approvals for the commercialization of his finished products.

[email protected]

Litho

Can

ada

| 20

12-0

9 3

K

Roughness Up to -19%

Maximum amplitude Up to -24%

Volume Up to -38%

Reduction of fat nodes

D0 D28

Effect on skin surface

Fat nodes (yellow)

ANTI-CELLULITE AND FIRMNESSTest protocol

- Application by 22 women (mean age 57) 2x/day of a cream containing 1% Body3 Complex™ on one thigh versus a placebo on the other thigh for a period of 28 days;

- Evaluation of anti-cellulite effect on cutaneous surface using Primos 3D Pico®; - Evaluation of firmness effect using Dermascan® (ultrasound technique).

Anti-cellulite actionBody3 Complex™ smoothes the skin’s surface and fades the orange-peel look.

Firming action - Redensifying effectBody3 Complex™ decreases fat clusters, leading to dermis redensification.

D0 D28 D56

Cellulite appearance reduction

D0 D56

Firming action

D0 D56

Stretch marks and slimming action

Placebo

D0

D28

-3% (ns)

Fat clusters (black)

Body3 ComplexTM

D0

D28

Conjunctive tissue (yellow to green)

+9%*dermis density

* p<0.005

*Distributed in France by Lucas Meyer Cosmetics / Unipex Solutions France.

Maximum redensifying effect up to +16%

CUTANEOUS SURFACE EVALUATION

-12

-10

-8

-6

-4

-2

0

2

4

6

Vari

ati

on

(%

vs.

D0

)

VolumeMaximumamplitude

Roughness

∆ -7%*

∆ -13%** ∆ -13%**

-10% -9% -9%

-3%

4% 4%

* p<0.05 **p<0.01

Placebo Body3 ComplexTM 1%

Active ingredients

pH: 5.0 - 5.5 - Viscosity (Rheo ELV 8, spindle 4, 6 rpm, 3 mn): 20 000 - 35 000 mPa.s

Page 6: ANTI CELLULITE AND FIRMNESS · Reduction of fat nodes D28 Effect on skin surface Fat nodes (yellow) ANTI!CELLULITE AND FIRMNESS Test protocol - Applica tion by 22 women (mean age

BODY3 COMPLEX™

3-in-1 Body Skin Enhancer

Unroasted shea butter and avocado seed extracts in bentonite-Triple action: reduces the appearance of cellulite and stretch marks and increases firmness

Body3 Complex™ reduces the appearance of cellulite and the orange-peel look, improves firmness and reduces the look of stretch marks.

Features and benefitsProduct descriptionINCI NAMEBentonite (1) (and) Butyrospermum Parkii (Shea) Butter Extract (2) (and) Persea Gratissima (Avocado) Fruit Extract (3)

CAS1302-78-9 (1), 91080-23-8 (2), 8024-32-6 (3)

EINECS215-108-5 (1), 293-515-7 (2), 232-428-0 (3)

ECOCERT / COSMOS STATUSRegistered

APPEARANCEOff-white to gray powder

FORMULATION Use below 40°C. Introduce via a premix phase: 1 part of Body3 ComplexTM for 5 to 7 parts of water.

DOSAGE - Preventive care: 0.1-0.5%- Treatment care: 0.5-1%

OPTIMUM pH < 9

APPLICATIONS- Slimming and reshaping products- Anti-cellulite products- Firming products- Anti-stretch mark products- Post-pregnancy treatment- Stomach-specific care- Anti-love handle treatment- Multifunctional body treatment

CHINA-COMPLIANT

FEATURES BENEFITS

Unique combination of 3 ingredients: unroasted shea butter extract, avocado seed extract incorporated in bentonite

Complete and multifunctional action

Roast-free shea butter processing method, preserving viminalol ester content

- Sustainable approach - Better slimming activity

3 levels of action (epidermis, dermis, hypodermis)

Triple action on cellulite, firmness and stretch marks

New lipolysis mechanism through ZAG modulation

Clinically proven results

Caffeine-like efficacy Slimming boosting effect

New mechanism for skin firmness via SKALP induction

Clinically proven results

Ultra-reshaping body3 gel-cream 12.237.09 C130

INGREDIENTS INCI NAME %

A Deionised Water Water 53.10

DermofeelTM PA-12* Sodium Phytate 0.20

Glycerin Glycerin 3.00

Granlux® AOX GL* Glycerin (and) Picea Excelsa Extract 1.00

EcogelTM Lysolecithin (and) Sclerotium Gum (and) Xanthan Gum (and) Pullulan

2.00

B Sweet Almond Oil Prunus Amygdalus Dulcis (Sweet Almond) Oil 5.00

Cetiol Sensoft Propylheptyl Caprylate 2.00

DermofeelTM G5DO* Polyglyceryl-5 Dioleate 1.00

C Body3 Complex™ Bentonite (and) Butyrospermum Parkii (Shea) Butter Extract (and) Persea Gratissima (Avocado) Fruit Extract

1.00

D Isocell™ Slim NC Caffeine (and) Sodium Salicylate (and) Lecithin (and) Silica

5.00

Deionised Water Water 20.00

E Aerosil 300 Silica 0.50

Sveltessence™ Glycerin (and) Water (and) Nephelium Longana Seed Extract

2.00

F Dermorganics™ 1388* Fragrance 4.00

G Bella Vita 3895 Fragrance 0.20

LUCAS MEYER COSMETICS S.A.S.

ZA les Belles Fontaines99 route de Versailles91160 Champlan - France T: +33 (0)1 69 10 69 69 - F: +33 (0)1 69 10 69 70

LUCAS MEYER COSMETICS CANADA INC.

Place de la Cité, Tour de la Cité2600 boul. Laurier, #900Québec (Québec) G1V 4W2 CanadaT: +1 418 653-6888 - F: +1 418 653-6005

This brochure is not intended for consumers and neither this brochure nor any extract thereof shall be used in order to commercialize products to consumers. No drawing, photograph or other extract derived from this brochure shall be used by any person without our prior written approval. As well, no claim with respect to the ingredient referred to in this brochure shall be made by any person without our prior written approval, even though the claim is set forth in this brochure. The person using the ingredient referred to in this brochure in the formulation of finished products is solely responsible for ensuring that the use made of the ingredient, the finished products marketed to consumers, their packaging, labelling and advertising materials and the claims made with respect to the finished products and the ingredient comply with all applicable laws and regulations. We hereby disclaim any warranty of suitability of the ingredient referred to in this brochure for any purpose. Any prospective user of the ingredient shall himself determine the suitability of the ingredient for his intended use and, as the case may be, obtain the required regulatory approvals for the commercialization of his finished products.

[email protected]

Litho

Can

ada

| 20

12-0

9 3

K

Roughness Up to -19%

Maximum amplitude Up to -24%

Volume Up to -38%

Reduction of fat nodes

D0 D28

Effect on skin surface

Fat nodes (yellow)

ANTI-CELLULITE AND FIRMNESSTest protocol

- Application by 22 women (mean age 57) 2x/day of a cream containing 1% Body3 Complex™ on one thigh versus a placebo on the other thigh for a period of 28 days;

- Evaluation of anti-cellulite effect on cutaneous surface using Primos 3D Pico®; - Evaluation of firmness effect using Dermascan® (ultrasound technique).

Anti-cellulite actionBody3 Complex™ smoothes the skin’s surface and fades the orange-peel look.

Firming action - Redensifying effectBody3 Complex™ decreases fat clusters, leading to dermis redensification.

D0 D28 D56

Cellulite appearance reduction

D0 D56

Firming action

D0 D56

Stretch marks and slimming action

Placebo

D0

D28

-3% (ns)

Fat clusters (black)

Body3 ComplexTM

D0

D28

Conjunctive tissue (yellow to green)

+9%*dermis density

* p<0.005

*Distributed in France by Lucas Meyer Cosmetics / Unipex Solutions France.

Maximum redensifying effect up to +16%

CUTANEOUS SURFACE EVALUATION

-12

-10

-8

-6

-4

-2

0

2

4

6

Vari

ati

on

(%

vs.

D0

)

VolumeMaximumamplitude

Roughness

∆ -7%*

∆ -13%** ∆ -13%**

-10% -9% -9%

-3%

4% 4%

* p<0.05 **p<0.01

Placebo Body3 ComplexTM 1%

Active ingredients

pH: 5.0 - 5.5 - Viscosity (Rheo ELV 8, spindle 4, 6 rpm, 3 mn): 20 000 - 35 000 mPa.s