ankylosing spondylitis clinical features
TRANSCRIPT
![Page 1: Ankylosing spondylitis clinical features](https://reader036.vdocuments.site/reader036/viewer/2022062300/5550511bb4c905b2788b53ca/html5/thumbnails/1.jpg)
Dr. Arohi Sharma
![Page 2: Ankylosing spondylitis clinical features](https://reader036.vdocuments.site/reader036/viewer/2022062300/5550511bb4c905b2788b53ca/html5/thumbnails/2.jpg)
![Page 3: Ankylosing spondylitis clinical features](https://reader036.vdocuments.site/reader036/viewer/2022062300/5550511bb4c905b2788b53ca/html5/thumbnails/3.jpg)
SpinalAge: early 20s to 40sSex M:F -7:1Backache or discomfort, Generalised,
Insiduous onset, Duration 3 monthsMorning stiffnessImproves with excercisePlueritic chest pain(costovertebral/
costosternal insertional tendinitis)
![Page 4: Ankylosing spondylitis clinical features](https://reader036.vdocuments.site/reader036/viewer/2022062300/5550511bb4c905b2788b53ca/html5/thumbnails/4.jpg)
Late SpinalFracture following trivial traumaAndersson lesionExtraspinalPeripheral Joint InvolvementPain, Swelling, EffusionAsymmetric Mostly Lower LimbTemperomandibular Joint Andersson
Lesion
![Page 5: Ankylosing spondylitis clinical features](https://reader036.vdocuments.site/reader036/viewer/2022062300/5550511bb4c905b2788b53ca/html5/thumbnails/5.jpg)
Extra-Articular Disease ManifestationFatigue, Weight loss, Low grade fever,
Anaemia, ESR raised
Chronic Prostatitis
Eyes Disease- Conjunctivitis, Iritis, Uveitis
![Page 6: Ankylosing spondylitis clinical features](https://reader036.vdocuments.site/reader036/viewer/2022062300/5550511bb4c905b2788b53ca/html5/thumbnails/6.jpg)
Pulmonary Disease- Upper Lobe Pulmonary Fibrosis Cough sputum,dyspnea
Cardiovascular Disease- Aortic Incompetence, Cardiomegaly, Cardiac conduction defects
Amyloidosis
Atlantoaxial subluxation/dislocation
![Page 7: Ankylosing spondylitis clinical features](https://reader036.vdocuments.site/reader036/viewer/2022062300/5550511bb4c905b2788b53ca/html5/thumbnails/7.jpg)
Nuerological Syndrome – Cauda Equina Syndrome
![Page 8: Ankylosing spondylitis clinical features](https://reader036.vdocuments.site/reader036/viewer/2022062300/5550511bb4c905b2788b53ca/html5/thumbnails/8.jpg)
Enthesopathic Lesion
Insertional Tendinitis- Achilles, Intercostal, Plantar Fascitis
Recurrent Episodes leaving behing new bone formation(Calcaneal Spur)
![Page 9: Ankylosing spondylitis clinical features](https://reader036.vdocuments.site/reader036/viewer/2022062300/5550511bb4c905b2788b53ca/html5/thumbnails/9.jpg)
Loss of cervical and lumbar lordosis
Paraspinal Muscle Spasm
Decreased Mobility symmetrically
Kyphotic Deformity leading toStooped over position
Chest flatteningSacro iliac pain
Hip flexion and adductionKnee FlexionShoulder internal rotation and adduction
![Page 10: Ankylosing spondylitis clinical features](https://reader036.vdocuments.site/reader036/viewer/2022062300/5550511bb4c905b2788b53ca/html5/thumbnails/10.jpg)
Chest expansionOcciput to wall distanceFinger to floor measurementIntermalleolar straddleChin to ChestSchober TestModified Schober Test
![Page 11: Ankylosing spondylitis clinical features](https://reader036.vdocuments.site/reader036/viewer/2022062300/5550511bb4c905b2788b53ca/html5/thumbnails/11.jpg)
![Page 12: Ankylosing spondylitis clinical features](https://reader036.vdocuments.site/reader036/viewer/2022062300/5550511bb4c905b2788b53ca/html5/thumbnails/12.jpg)
Modified Schober
![Page 13: Ankylosing spondylitis clinical features](https://reader036.vdocuments.site/reader036/viewer/2022062300/5550511bb4c905b2788b53ca/html5/thumbnails/13.jpg)
Straight leg raising testCompression stress testDistraction stress testAxial Rotation stress test Pump Handle Gaenslen Test Laquer’s Sign Goldthwaite Sign
![Page 14: Ankylosing spondylitis clinical features](https://reader036.vdocuments.site/reader036/viewer/2022062300/5550511bb4c905b2788b53ca/html5/thumbnails/14.jpg)
![Page 15: Ankylosing spondylitis clinical features](https://reader036.vdocuments.site/reader036/viewer/2022062300/5550511bb4c905b2788b53ca/html5/thumbnails/15.jpg)
![Page 16: Ankylosing spondylitis clinical features](https://reader036.vdocuments.site/reader036/viewer/2022062300/5550511bb4c905b2788b53ca/html5/thumbnails/16.jpg)
![Page 17: Ankylosing spondylitis clinical features](https://reader036.vdocuments.site/reader036/viewer/2022062300/5550511bb4c905b2788b53ca/html5/thumbnails/17.jpg)
![Page 18: Ankylosing spondylitis clinical features](https://reader036.vdocuments.site/reader036/viewer/2022062300/5550511bb4c905b2788b53ca/html5/thumbnails/18.jpg)
![Page 19: Ankylosing spondylitis clinical features](https://reader036.vdocuments.site/reader036/viewer/2022062300/5550511bb4c905b2788b53ca/html5/thumbnails/19.jpg)
![Page 20: Ankylosing spondylitis clinical features](https://reader036.vdocuments.site/reader036/viewer/2022062300/5550511bb4c905b2788b53ca/html5/thumbnails/20.jpg)
![Page 21: Ankylosing spondylitis clinical features](https://reader036.vdocuments.site/reader036/viewer/2022062300/5550511bb4c905b2788b53ca/html5/thumbnails/21.jpg)
Clinical Criteria◦ Low back pain, > 3
months, improved by exercise, not relieved by rest
◦ Limitation of lumbar spine motion, sagittal and frontal planes
◦ Limitation of chest expansion relative to normal values for age and sex
21
• Radiologic Criteria
– Sacroiliitis grade 2 bilaterally or grade 3 – 4 unilaterally
• Grading
– Definite AS if radiologic criterion present plus at least one clinical criteria
– Probable AS if:• Three clinical criterion• Radiologic criterion
present, but no signs or symptoms satisfy clinical criteria
![Page 22: Ankylosing spondylitis clinical features](https://reader036.vdocuments.site/reader036/viewer/2022062300/5550511bb4c905b2788b53ca/html5/thumbnails/22.jpg)
Index Metric
BASFI Disability level
BASDAI Disease activity level
ASAS - IC Composite sum of disease activity
22
BASFI = Bath Ankylosing Spondylitis Functional IndexBASDAI = Bath Ankylosing Spondylitis Disease Activity IndexASAS - IC = ASsessment in Ankylosing Spondylitis Improvement Criteria
![Page 23: Ankylosing spondylitis clinical features](https://reader036.vdocuments.site/reader036/viewer/2022062300/5550511bb4c905b2788b53ca/html5/thumbnails/23.jpg)
Visual analog scale (VAS) – 10 cm Mean score of 10 questions Questions level of functional disability,
including:◦ Ability to bend at the waist and perform tasks◦ Looking over your shoulder without turning your body◦ Standing unsupported for 10 minutes without
discomfort◦ Rising from a seated position without the use of an aid◦ Exercising and performing strenuous activity◦ Performing daily activities of living◦ Climbing 12 to 15 steps without aid
23
![Page 24: Ankylosing spondylitis clinical features](https://reader036.vdocuments.site/reader036/viewer/2022062300/5550511bb4c905b2788b53ca/html5/thumbnails/24.jpg)
A self-administered instrument (using 10-cm horizontal visual analog scales) that comprises 6 questions:
Over the last one week, how would you describe the overall level of:◦ Fatigue/tiredness ◦ AS spinal (back, neck) or hip pain◦ Pain/swelling in joints other than above ◦ Level of discomfort from tender areas ◦ Morning stiffness from the time you awake◦ How long does morning stiffness last?
24
![Page 25: Ankylosing spondylitis clinical features](https://reader036.vdocuments.site/reader036/viewer/2022062300/5550511bb4c905b2788b53ca/html5/thumbnails/25.jpg)
ASAS 20: An improvement of > 20% and absolute improvement of > 10 units on a 0–100 scale in > 3 of the following 4 domains:◦ Patient global assessment (by VAS global assessment)◦ Pain assessment (the average of VAS total and nocturnal
pain scores)◦ Function (represented by BASFI)◦ Inflammation (the average of the BASDAI’s last two VAS
concerning morning stiffness intensity and duration) Absence of deterioration in the potential remaining
domain◦ (deterioration is defined as > 20% worsening)
25
![Page 26: Ankylosing spondylitis clinical features](https://reader036.vdocuments.site/reader036/viewer/2022062300/5550511bb4c905b2788b53ca/html5/thumbnails/26.jpg)