anal cancer clinical

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ANAL CANCER CLINICAL TRIALS

DISCLAIMER:- The Following Clinical Trials are from our 2005 review and areNOT in our current reviews. They are listed only as examples of how comprehensiveour clinical trials are.

rHuEPO and treatment outcomes: the clinical experience.

Hudis CA, Van Belle S, Chang J, Muenstedt K.

Breast Cancer Medicine Service, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue,New York, NY 10021, USA. [email protected]

Increasingly, anemia is being recognized as a negative prognostic and predictive factor forpatients undergoing chemotherapy, radiation therapy, or a combination of these treatmentmodalities. The results of clinical studies have shown correlations between anemia and shortersurvival times in patients with a wide variety of solid tumors and hematologic malignancies,including lung, ovarian, breast, and head/neck cancers, non-Hodgkin's lymphoma, Hodgkin'sdisease, Waldenstrom's macroglobulinemia, and chronic lymphocytic leukemia. Also, anemia hasbeen shown to predict treatment response in patients with ovarian, cervical, and urothelialcancers, mantle cell lymphoma, and chronic lymphocytic leukemia, as well as refractory/relapsedacute myelogenous leukemia. Based on the presumed causal relationship between anemia andpoor patient outcome, several studies have examined the influence of epoetin alfa (a recombinanthuman erythropoietin) on outcomes in anemic patients undergoing cancer treatment. The resultsof these studies have been encouraging, with indications of greater locoregional tumor controland higher response rates in epoetin alfa-treated patients. Additionally, epoetin alfa therapy, bycorrecting anemia, has been shown to improve a patient's energy level, ability to perform daily

activities, and overall quality of life (QOL). Such effects not only enhance a patient's generalwell-being, but may also increase their tolerance of, and willingness to undergo, full courses oftheir cancer therapy in a timely manner. These findings support the use of epoetin alfa to achievegains in QOL and cancer treatment outcomes in anemic cancer patients and suggest thatadditional studies be conducted to further investigate the potential benefits of this agent in regardto improved outcomes.

SB-715992 in Treating Patients With Acute Leukemia, Chronic Myelogenous Leukemia, orAdvanced Myelodysplastic Syndromes.RATIONALE: Drugs used in chemotherapy, such as SB-715992, work in different ways to stopcancer cells from dividing so they stop growing or die.

PURPOSE: Phase I trial to study the effectiveness of SB-715992 in treating patients who haveacute leukemia, chronic myelogenous leukemia, or advanced myelodysplastic syndromes.California

City of Hope Comprehensive Cancer Center, Duarte, California, 91010-3000, UnitedStates; RecruitingClinical Trials Office - New Patient Services 800-826-4673 [email protected]

Ohio


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Ireland Cancer Center at University Hospitals of Cleveland and Case Western ReserveUniversity, Cleveland, Ohio, 44106-5055, United States; RecruitingBrenda W. Cooper, MD 216-844-3213 [email protected]

Sirolimus in Treating Young Patients With Relapsed or Refractory Acute Leukemia.RATIONALE: Drugs used in chemotherapy such as sirolimus use different ways to stop cancercells from dividing so they stop growing or die.PURPOSE: Phase I trial to study the effectiveness of sirolimus in treating young patients whohave relapsed or refractory acute leukemia or non-Hodgkin's lymphoma.Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, 19104, UnitedStates; Recruiting Susan Rheingold, MD 215-590-2801 [email protected]

Flavopiridol, Cytarabine, and Mitoxantrone in Treating Patients With Acute Leukemia.RATIONALE: Drugs used in chemotherapy work in different ways to stop cancer cells fromdividing so they stop growing or die. Combining more than one drug may kill more cancer cells.

PURPOSE: Phase II trial to study the effectiveness of combining flavopiridol and cytarabinewith mitoxantrone in treating patients who have acute leukemia.Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland,21231, United States; Recruiting Judith E. Karp, MD 410-502-7726

3-AP Followed By Fludarabine In Treating Patients With Relapsed or Refractory Acute orChronic Leukemia.RATIONALE: Drugs used in chemotherapy, such as fludarabine, work in different ways to stopcancer cells from dividing so they stop growing or die. 3-AP may help fludarabine kill morecancer cells by making them more sensitive to the drug.PURPOSE: This phase I trial is studying the side effects and best dose of fludarabine when giventogether with 3-AP in treating patients with relapsed or refractory acute leukemia, chronicleukemia, or high-risk myelodysplastic syndrome.Georgia

Blood and Marrow Transplant Group of Georgia, Atlanta, Georgia, 30342-4777, UnitedStates; RecruitingLawrence E. Morris, MD 404-255-1930 [email protected]

MarylandGreenebaum Cancer Center at University of Maryland Medical Center, Baltimore,

Maryland, 21201, United States; RecruitingIvana Gojo, MD 410-328-2565

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland,21231, United States; RecruitingJudith E. Karp, MD 410-502-7726

TexasMD Anderson Cancer Center at University of Texas, Houston, Texas, 77030-4095, United

States; RecruitingFrancis J. Giles, MD 713-792-7305 [email protected]


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Monoclonal Antibody Therapy in Treating Patients With Ovarian Epithelial Cancer, Melanoma,Acute Myeloid Leukemia.RATIONALE: Monoclonal antibodies can locate tumor cells and either kill them or delivertumor-killing substances to them without harming normal cells.PURPOSE: Phase I trial to study the effectiveness of monoclonal antibody therapy in treatingpatients who have acute myeloid leukemia.Dana-Farber/Harvard Cancer Center at Dana Farber Cancer Institute, Boston, Massachusetts,02115, United States; Recruiting F. Stephen Hodi, MD 617-632-5053

Combination Chemotherapy and Rituximab in Treating Young Patients With Recurrent orRefractory Acute Lymphoblastic Leukemia.

RATIONALE: Chemotherapy drugs, such as ifosfamide, carboplatin, and etoposide, work indifferent ways to stop cancer cells from dividing so they stop growing or die. Monoclonalantibodies such as rituximab can locate cancer cells and either kill them or deliver cancer-killingsubstances to them without harming normal cells. Combining ifosfamide, carboplatin, and

etoposide with rituximab may kill more cancer cells.PURPOSE: This phase II trial is studying how well rituximab together with ifosfamide,carboplatin, and etoposide works in treating young patients with recurrent or refractory acutelymphoblastic leukemia.

AlabamaUniversity of Alabama at Birmingham Comprehensive Cancer Center, Birmingham,

Alabama, 35233, United States; RecruitingRobert P. Castleberry, MD 205-939-9285 [email protected]

University of South Alabama Cancer Research Institute, Mobile, Alabama, 36604, United

States; RecruitingFelicia L. Wilson, MD 251-405-5115 [email protected]

ArizonaArizona Cancer Center at University of Arizona Health Sciences Center, Tucson, Arizona,

85724, United States; RecruitingRochelle Bagatell, MD 520-626-4851

Phoenix Children's Hospital, Phoenix, Arizona, 85016, United States; RecruitingJessica Boklan, MD 602-546-0920

ArkansasArkansas Cancer Research Center at University of Arkansas for Medical Sciences, Little

Rock, Arkansas, 72205, United States; RecruitingDavid L. Becton, MD 501-320-5650

CaliforniaChao Family Comprehensive Cancer Center at University of California Irvine Medical

Center, Orange, California, 92868, United States; RecruitingStanley Calderwood, MD 714-456-6615 [email protected]


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Lucile Packard Children's Hospital at Stanford University Medical Center, Palo Alto,California, 94304, United States; Recruiting Neyssa M. Marina, MD 650-723-5535 [email protected]

Rebecca and John Moores UCSD Cancer Center, La Jolla, California, 92093-0658, UnitedStates; RecruitingRichard Kadota, MD 858-657-7020

Samuel Oschin Comprehensive Cancer Institute at Cedars-Sinai Medical Center, LosAngeles, California, 90048, United States; RecruitingMoshe Arditi, MD 310-423-4471

Santa Barbara Cottage Hospital, Santa Barbara, California, 93102, UnitedStates; RecruitingFelicity Hodder, MD 805-682-7111 [email protected]

Southern California Permanente Medical Group, Downey, California, 90242, UnitedStates; RecruitingWillye B. Powell, MD 562-803-2472

Sutter Cancer Center, Sacramento, California, 95816, United States; RecruitingYisheng Lee, MD, PhD, MBA 916-733-1757

UCSF Comprehensive Cancer Center, San Francisco, California, 94143, UnitedStates; RecruitingKatherine K. Matthay, MD 415-476-3831

University of California Davis Cancer Center, Sacramento, California, 95817, UnitedStates; RecruitingTheodore Zwerdling, MD 916-734-2781 [email protected]

ColoradoChildren's Hospital Cancer Center, Denver, Colorado, 80218, United States; Recruiting

Roger Howard Giller, MD 303-861-6892 [email protected]

Presbyterian - St. Luke's Medical Center, Denver, Colorado, 80218, UnitedStates; RecruitingStephen R. Palmer, MD 719-471-2462

ConnecticutCarole and Ray Neag Comprehensive Cancer Center at the University of Connecticut Health

Center, Farmington, Connecticut, 06360-7106, United States; RecruitingArnold J. Altman, MD 860-545-9630

Yale Comprehensive Cancer Center, New Haven, Connecticut, 06520-8064, UnitedStates; RecruitingJack van Hoff, MD 203-785-4640 [email protected]


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DelawareAlfred I. duPont Hospital for Children, Wilmington, Delaware, 19899, United

States; RecruitingRita S. Meek, MD 302-651-5502 [email protected]

District of ColumbiaChildren's National Medical Center, Washington, District of Columbia, 20010-2970, United

States; Recruiting Nita Louise Seibel, MD 202-884-2144 [email protected]

Lombardi Cancer Center at Georgetown University Medical Center, Washington, District ofColumbia, 20007, United States; RecruitingAziza Shad, MD 202-444-2224 [email protected]

FloridaAll Children's Hospital, St. Petersburg, Florida, 33701, United States; Recruiting

Jerry L. Barbosa, MD 727-892-4231 [email protected]

Baptist-South Miami Regional Cancer Program, Miami, Florida, 33176-2197, UnitedStates; RecruitingDoured Daghistani, MD 786-596-1960

Broward General Medical Center, Fort Lauderdale, Florida, 33316, UnitedStates; RecruitingRudolph R. Roskos, MD 954-355-4527 [email protected]

Children's Hospital of Southwest Florida, Fort Myers, Florida, 33908, UnitedStates; RecruitingEmad K. Salman, MD 239-432-3333 [email protected]

Florida Hospital Cancer Institute, Orlando, Florida, 32804, United States; RecruitingJane Crofton, RN, BSN, OCN 407-303-2090

Jackson Memorial Hospital, Miami, Florida, 33136, United States; RecruitingStuart R. Toledano, MD 305-585-5635 [email protected]

Joe DiMaggio Children's Hospital at Memorial, Hollywood, Florida, 33021, UnitedStates; RecruitingIftikhar Hanif, MD 954-986-2234 [email protected]

Miami Children's Hospital, Miami, Florida, 33155, United States; RecruitingEnrique A. Escalon, MD 305-666-6511

Nemours Children's Clinic, Jacksonville, Florida, 32207, United States; RecruitingEric Sandler, MD 904-390-3793 [email protected]

Nemours Children's Clinic-Orlando, Orlando, Florida, 32806, United States; Recruiting


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Vincent F. Giusti, MD 407-650-7230

Sacred Heart Children's Hospital, Pensacola, Florida, 32504, United States; RecruitingJohn F. Kelleher, MD 850-505-4798 [email protected]

Shands Cancer Center at the University of Florida Health Science Center, Gainesville,Florida, 32610-0296, United States; RecruitingStephen P. Hunger, MD 352-392-5633 [email protected]

St. Joseph's Children's Hospital, Tampa, Florida, 33677-4227, United States; RecruitingCameron K. Tebbi, MD 813-870-4252 [email protected]

St. Mary's Hospital, West Palm Beach, Florida, 33407, United States; Recruiting Narayana Gowda, MD 561-840-6125 [email protected]

GeorgiaAFLAC Cancer Center and Blood Disorders Service of Children's Healthcare of Atlanta -

Scottish Rite Campus, Atlanta, Georgia, 30342, United States; RecruitingHoward M. Katzenstein, MD 404-785-0853 [email protected]

Curtis & Elizabeth Anderson Cancer Institute at Memorial Health University MedicalCenter, Savannah, Georgia, 31405, United States; RecruitingTribhawan S. Vats, MD 912-350-8194 [email protected]

MBCCOP-Medical College of Georgia Cancer Center, Augusta, Georgia, 30912-4000,United States; RecruitingRoger A. Vega, MD 706-721-3626

Medical Center of Central Georgia, Macon, Georgia, 31201, United States; RecruitingHassan Dannawi, MD 478-633-1104 [email protected]

HawaiiCancer Research Center of Hawaii, Honolulu, Hawaii, 96813, United States; Recruiting

Robert Warren Wilkinson, MD 808-586-2979

MBCCOP - Hawaii, Honolulu, Hawaii, 96813, United States; RecruitingBrian F. Issell, MD 808-586-3015 [email protected]

Tripler Army Medical Center, Honolulu, Hawaii, 96859-5000, United States; RecruitingBraden Alan Shoupe, MD 808-433-6057

IdahoMountain States Tumor Institute - Boise, Boise, Idaho, 83712, United States; Recruiting

J. Martin Johnston, MD 208-381-2782 [email protected]

IllinoisAdvocate Hope Children's Hospital, Oak Lawn, Illinois, 60453, United States; Recruiting

Sharad N. Salvi, MD 708-346-4094 [email protected]


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Children's Memorial Hospital - Chicago, Chicago, Illinois, 60614, UnitedStates; RecruitingSusan Lerner Cohn, MD 773-880-4562

Lutheran General Cancer Care Center, Park Ridge, Illinois, 60068-1174, UnitedStates; RecruitingJong-Hyo Kwon, MD 847-723-5962 [email protected]

Rush University Medical Center, Chicago, Illinois, 60612, United States; RecruitingAllen D. Korenblit, MD 312-942-5983 [email protected]

Saint Jude Midwest Affiliate, Peoria, Illinois, 61637, United States; RecruitingJohn A. McCallister, MD 309-624-4945 [email protected]

Southern Illinois University School of Medicine, Springfield, Illinois, 62794-9658, UnitedStates; Recruiting

Gregory Brandt, MD 217-545-5817 [email protected]

University of Chicago Cancer Research Center, Chicago, Illinois, 60601, UnitedStates; RecruitingJames B. Nachman, MD 773-702-6808

University of Illinois Medical Center, Chicago, Illinois, 60612, United States; RecruitingMary Lou Schmidt, MD 312-996-6143 [email protected]

IndianaRiley Children Cancer Center at Riley Hospital for Children, Indianapolis, Indiana, 46202-

5225, United States; RecruitingRobert Fallon, MD, PhD 317-274-8784 [email protected]

St. Vincent Hospitals and Health Care Centers, Indianapolis, Indiana, 46260, UnitedStates; RecruitingRandy Alan Hock, MD, PhD, MMM 317-338-4673

IowaBlank Children's Hospital, Des Moines, Iowa, 50308, United States; Recruiting

Torrey Leighton Mitchell, MD 515-241-8912 [email protected]

Holden Comprehensive Cancer Center at University of Iowa, Iowa City, Iowa, 52242-1009,

United States; RecruitingRaymond Tannous, MD 319-356-1905

John Stoddard Cancer Center at Iowa Methodist Medical Center, Des Moines, Iowa, 50309,United States; RecruitingStephen C. Elliott, DO, PhD, FAAP 515-241-6000 [email protected]

Kansas


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Wesley Medical Center, Wichita, Kansas, 67214, United States; RecruitingDavid Rosen, MD 316-962-2025

KentuckyKosair Children's Hospital, Louisville, Kentucky, 40202-3830, United States; Recruiting

Salvatore J. Bertolone, MD 502-852-8450

Markey Cancer Center at University of Kentucky Chandler Medical Center, Lexington,Kentucky, 40536-0284, United States; RecruitingMartha F. Greenwood, MD 859-323-6771 [email protected]

LouisianaChildren's Hospital of New Orleans, New Orleans, Louisiana, 70118, United

States; RecruitingLolie Chua Yu, MD 504-896-9740

MBCCOP - LSU Health Sciences Center, New Orleans, Louisiana, 70112, United

States; RecruitingJill Gilbert, MD 504-568-5613 [email protected]

Ochsner Cancer Institute at Ochsner Clinic Foundation, New Orleans, Louisiana, 70121,United States; RecruitingMarquis Zimri Hodes, MD, PhD 504-842-5230

Tulane Cancer Center at Tulane University Hospital and Clinic, New Orleans, Louisiana,70112, United States; RecruitingMarshall A. Schorin, MD 504-988-5412 [email protected]

MaineCancerCare of Maine at Eastern Maine Medial Center, Bangor, Maine, 04401, United

States; RecruitingJudith B. Allen, MD 207-973-7520

Maine Children's Cancer Program, Scarborough, Maine, 04074-9308, UnitedStates; RecruitingCraig A. Hurwitz, MD 207-885-7565 [email protected]

MarylandAlvin and Lois Lapidus Cancer Institute at Sinai Hospital, Baltimore, Maryland, 21225,

United States; Recruiting

Joseph Michael Wiley, MD 410-601-5864 [email protected]

Greenebaum Cancer Center at University of Maryland Medical Center, Baltimore,Maryland, 21201-1595, United States; Recruiting Neil Jeffrey Grossman, MD 410-328-2808 [email protected]

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland,21231-2410, United States; Recruiting


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Cindy Schwartz, MD 410-955-7385 [email protected]

Walter Reed Army Medical Center, Silver Spring, Maryland, 20910, UnitedStates; RecruitingKip R. Hartman, MD 301-319-9116

MassachusettsBaystate Regional Cancer Program at D'Amour Center for Cancer Care, Springfield,

Massachusetts, 01107, United States; RecruitingDavid A. Steele, MD 413-794-9338 [email protected]

Dana-Farber/Harvard Cancer Center at Dana Farber Cancer Institute, Boston,Massachusetts, 02115, United States; RecruitingHolcombe Edwin Grier, MD 617-632-3971 [email protected]

Floating Hospital for Children, Boston, Massachusetts, 02111, United States; RecruitingCynthia S. Kretschmar, MD 617-636-5535 [email protected]

UMASS Memorial Cancer Center - University Campus, Worcester, Massachusetts, 01655,United States; RecruitingGhazala Naheed Usmani, MD 508-856-4225 [email protected]

MichiganBreslin Cancer Center at Ingham Regional Medical Center, Lansing, Michigan, 48910,

United States; RecruitingRenuka Gera, MD 517-334-2337

Bronson Methodist Hospital, Kalamazoo, Michigan, 49007-5364, United States; Recruiting

Leonard August Mattano, MD, PhD 616-341-6350

CCOP - Beaumont, Royal Oak, Michigan, 48073-6769, United States; RecruitingJeanne Archer, PhD, APN 248-551-8299 [email protected]

Children's Hospital of Michigan, Detroit, Michigan, 48201, United States; RecruitingYaddanapudi Ravindranath, MBBS 313-745-5649 [email protected]

DeVos Children's Hospital, Grand Rapids, Michigan, 49503, United States; RecruitingDavid Robert Freyer, DO 616-391-2086

Hurley Medical Center, Flint, Michigan, 48503, United States; RecruitingSusumu Inoue, MD 810-762-7303 [email protected]

Josephine Ford Cancer Center at Henry Ford Health System, Detroit, Michigan, 48202,United States; RecruitingHassan M. Yaish, MD 313-916-3138

University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan, 48109-0914,


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United States; RecruitingRaymond J. Hutchinson, MD 734-936-8785

Van Elslander Cancer Center at St. John Hospital and Medical Center, Detroit, Michigan,48236, United States; RecruitingHadi Sawaf, MD 313-647-3200 [email protected]

William Beaumont Hospital - Royal Oak, Royal Oak, Michigan, 48073-6769, UnitedStates; RecruitingCharles A. Main, MD 248-551-0360

MinnesotaChildren's Hospitals and Clinics - Minneapolis/St. Paul, Minneapolis, Minnesota, 55404,

United States; RecruitingMaura C. O'Leary, MD 612-813-5940

Mayo Clinic Cancer Center, Rochester, Minnesota, 55905, United States; Recruiting

Carola A.S. Arndt, MD 507-284-2695 [email protected]

St. Mary's - Duluth Clinic Cancer Center, Duluth, Minnesota, 55805, UnitedStates; RecruitingJacquelyn Dawn Wiermaa, MD 218-786-3625

MississippiUniversity of Mississippi Medical Center, Jackson, Mississippi, 39216-4505, United

States; RecruitingDale Jeanette Pullen, MD 601-984-5220

MissouriCardinal Glennon Children's Hospital, Saint Louis, Missouri, 63104, United

States; RecruitingWilliam Shay Ferguson, MD 314-577-5638

Children's Mercy Hospital, Kansas City, Missouri, 64108, United States; RecruitingMaxine L. Hetherington, MD 816-234-3265

St. Louis Children's Hospital, Saint Louis, Missouri, 63110, United States; RecruitingRobert James Hayashi, MD 314-454-4118 [email protected]

University of Missouri - Columbia, Columbia, Missouri, 65203, United States; Recruiting

Barbara Anne Gruner, MD 573-882-3961 [email protected]

NebraskaChildren's Hospital of Omaha, Omaha, Nebraska, 68114, United States; Recruiting

Minnie Abromowitch, MD 402-955-3949 [email protected]

UNMC Eppley Cancer Center at the University of Nebraska Medical Center, Omaha,Nebraska, 68198-2168, United States; Recruiting


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Peter F. Coccia, MD 402-559-7257 [email protected]

NevadaSunrise Hospital and Medical Center, Las Vegas, Nevada, 89109, United States; Recruiting

Jonathan Bernstein, MD 702-732-0971 [email protected]

New HampshireNorris Cotton Cancer Center at Dartmouth-Hitchcock Medical Center, Lebanon, New

Hampshire, 03756, United States; RecruitingEric Christian Larsen, MD 603-650-5541 [email protected]

New JerseyCancer Center at Hackensack University Medical Center, Hackensack, New Jersey, 07601,

United States; RecruitingMichael B. Harris, MD 201-996-5437 [email protected]

Cancer Institute of New Jersey at UMDNJ - Robert Wood Johnson Medical School, New

Brunswick, New Jersey, 08903, United States; RecruitingRichard A. Drachtman, MD 732-235-5437 [email protected]

Newark Beth Israel Medical Center, Newark, New Jersey, 07112-2094, UnitedStates; RecruitingPeri Kamalakar, MD 973-926-7161 [email protected]

St. Joseph's Hospital and Medical Center, Paterson, New Jersey, 07503, UnitedStates; RecruitingMary Ann Bonilla, MD 973-754-3230 [email protected]

Valerie Fund Children's Center at Atlantic Health, Summit, New Jersey, 07901, UnitedStates; RecruitingHazem Helmy Mahmoud, MD 973-971-6731

New MexicoUniversity of New Mexico Cancer Research and Treatment Center, Albuquerque, New

Mexico, 87131, United States; RecruitingJami Frost, MD 505-272-4461

New YorkAlbert Einstein Cancer Center at Albert Einstein College of Medicine, Bronx, New York,

10461, United States; Recruiting

Eva Radel, MD 718-920-7844

Brookdale University Hospital and Medical Center, Brooklyn, New York, 11212, UnitedStates; RecruitingKusum Viswanathan, MD 718-240-5904

Brooklyn Hospital Center, Brooklyn, New York, 11201-5493, United States; RecruitingSwayamprabha Sadanandan, MD 718-250-6074 [email protected]


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Cancer Center of Albany Medical Center, Albany, New York, 12208, UnitedStates; RecruitingJennifer M. Pearce, MD 518-262-5513 [email protected]

Comprehensive Cancer Center at Maimonides Medical Center, Brooklyn, New York,11219, United States; RecruitingLudovico Guarini, MD 718-283-8173 [email protected]

Herbert Irving Comprehensive Cancer Center at Columbia University, New York, NewYork, 10032, United States; RecruitingLinda Granowetter, MD 212-305-8652 [email protected]

James P. Wilmot Cancer Center at University of Rochester Medical Center, Rochester, NewYork, 14642, United States; RecruitingBarbara Lawrence Asselin, MD 716-275-2981

Long Island Cancer Center at Stony Brook University Hospital, Stony Brook, New York,11794, United States; RecruitingRobert Ingalls Parker, DSc 631-444-4000

Memorial Sloan-Kettering Cancer Center, New York, New York, 10021, UnitedStates; RecruitingPeter G. Steinherz, MD 212-639-7951

Mount Sinai School of Medicine, New York, New York, 10029, United States; RecruitingElizabeth Raetz, MD 212-241-7022

New York Medical College, Valhalla, New York, 10595, United States; RecruitingM. Fevzi Ozkaynak, MD 914-493-7997 [email protected]

New York Weill Cornell Cancer Center at Cornell University, New York, New York, 10021,United States; RecruitingPatricia J.V. Giardina, MD 212-746-3400

Schneider Children's Hospital, New Hyde Park, New York, 11042, UnitedStates; RecruitingArlene Sara Redner, MD 718-470-3460

SUNY Downstate Medical Center, Brooklyn, New York, 11203, United States; Recruiting

Sreedhar P. Rao, MD 718-270-1693

SUNY Upstate Medical University Hospital, Syracuse, New York, 13210, UnitedStates; RecruitingRonald L. Dubowy, MD 315-464-5294 [email protected]

North CarolinaBlumenthal Cancer Center at Carolinas Medical Center, Charlotte, North Carolina, 28232-


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2861, United States; RecruitingDaniel P. McMahon, MD 704-355-1130 [email protected]

Comprehensive Cancer Center at Wake Forest University, Winston Salem, North Carolina,27157-1081, United States; RecruitingThomas Williams McLean, MD 336-716-4324

Duke Comprehensive Cancer Center, Durham, North Carolina, 27710, UnitedStates; RecruitingPhilip Paul Breitfeld, MD 919-684-3377

Leo W. Jenkins Cancer Center at Pitt County Memorial Hospital, Greenville, NorthCarolina, 27858-4354, United States; RecruitingCharles W. Daeschner, MD 252-744-4676 [email protected]

Lineberger Comprehensive Cancer Center at University of North Carolina - ChapelHill, Chapel Hill, North Carolina, 27599, United States; Recruiting

Stuart Gold, MD 919-966-0985 [email protected]

Mission Hospitals, Asheville, North Carolina, 28801, United States; RecruitingOrren Beaty, DO, PhD 823-213-5770 [email protected]

Presbyterian Cancer Center at Presbyterian Hospital, Charlotte, North Carolina, 28233,United States; RecruitingMark Mogul, MD 704-384-1900

North DakotaDakota Cancer Institute at Innovis Health - Dakota Clinic, Fargo, North Dakota, 58103-

4940, United States; RecruitingJanet K. Tillisch, MD 701-364-4964

OhioChildren's Hospital Medical Center of Akron, Akron, Ohio, 44308-1062, United

States; RecruitingSteven J. Kuerbitz, MD 330-543-8730 [email protected]

Children's Medical Center - Dayton, Dayton, Ohio, 45404, United States; RecruitingEmmett H. Broxson, MD, FAAP 937-641-3111 [email protected]

Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, 45229-3039, United

States; RecruitingJohn Peter Perentesis, MD 513-636-6090

Cleveland Clinic Taussig Cancer Center, Cleveland, Ohio, 44195, United States; Recruiting

Karen A. Bringelsen, MD 216-444-7923

Columbus Children's Hospital, Columbus, Ohio, 43205-2696, United States; Recruiting


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Amanda Termuhlen, MD 614-722-3552

Forum Health-Tod Childrens Hospital, Youngstown, Ohio, 44501, UnitedStates; RecruitingAyman Saleh, MD, FAAP 330-884-3955 [email protected]

Ireland Cancer Center at University Hospitals of Cleveland and Case Western ReserveUniversity, Cleveland, Ohio, 44106-5065, United States; RecruitingSusan Wiersma, MD 216-844-3345 [email protected]

St. Vincent Mercy Medical Center, Toledo, Ohio, 43608, United States; RecruitingRama Jasty, MD 419-251-8215 [email protected]

Toledo Children's Hospital, Toledo, Ohio, 43601, United States; RecruitingRichard M. Shore, MD 419-471-5437

Oklahoma

CCOP - Oklahoma, Tulsa, Oklahoma, 74136, United States; RecruitingJames B. Lockhart, MD 918-491-5878

Children's Hospital at Oklahoma University Medical Center, Oklahoma City, Oklahoma,73104, United States; RecruitingWilliam H. Meyer, MD 405-271-5311 [email protected]

Natalie Warren Bryant Cancer Center at St. Francis Hospital, Tulsa, Oklahoma, 74136,United States; RecruitingMartina Christine Hum, MD 918-494-2525 [email protected]

OregonCCOP - Columbia River Oncology Program, Portland, Oregon, 97225, United

States; RecruitingKeith S. Lanier, MD 503-216-6260

Doernbecher Children's Hospital at Oregon Health & Science University, Portland, Oregon,97239-3098, United States; RecruitingH. Stacy Nicholson, MD, MPH 503-494-1543

Legacy Emanuel Hospital and Health Center & Children's Hospital, Portland, Oregon,97227, United States; RecruitingJanice Faye Olson, MD 503-413-2200

PennsylvaniaChildren's Hospital at Milton S. Hershey Medical Center, Hershey, Pennsylvania, 17033,

United States; RecruitingJohn E. Neely, MD 717-531-6012 [email protected]

Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, 19104, UnitedStates; Recruiting


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Richard Berry Womer, MD 215-590-2229 [email protected]

Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania, 15213, UnitedStates; RecruitingArthur Kim Ritchey, MD 412-692-5055 [email protected]

Geisinger Medical Center, Danville, Pennsylvania, 17822-1320, United States; RecruitingJeffrey Taylor, MD 570-271-6848

St. Christopher's Hospital for Children, Philadelphia, Pennsylvania, 19134-1095, UnitedStates; RecruitingGregory E. Halligan, MD 215-427-5000 [email protected]

Rhode IslandRhode Island Hospital, Providence, Rhode Island, 02903, United States; Recruiting

Sam W. Lew, MD 401-444-5171

South CarolinaChildren's Hospital of Greenville Hospital System, Greenville, South Carolina, 29605,

United States; RecruitingCary Ernest Stroud, MD 864-455-8898

Hollings Cancer Center at Medical University of South Carolina, Charleston, SouthCarolina, 29425-0721, United States; RecruitingJulio C. Barredo, MD 843-792-2957 [email protected]

Palmetto Health South Carolina Cancer Center, Columbia, South Carolina, 29203, UnitedStates; RecruitingRonnie W. Neuberg, MD 803-434-3533 [email protected]

South DakotaAvera Cancer Institute, Sioux Falls, South Dakota, 57105-1080, United States; Recruiting

Marwan D. Hanna, MD 605-322-7595

Sioux Valley Hospital and University of South Dakota Medical Center, Sioux Falls, SouthDakota, 57117-5039, United States; RecruitingJakica Tancabelic, MD 605-333-7171 [email protected]

TennesseeEast Tennessee Children's Hospital, Knoxville, Tennessee, 37901, United States; Recruiting

Ray C. Pais, MD 865-541-8266 [email protected]

East Tennessee State University Cancer Center at Johnson City Medical Center, JohnsonCity, Tennessee, 37614-0622, United States; RecruitingDavid K. Kalwinsky, MD 423-433-6200 sjcrhta@msha,cin

St. Jude Children's Research Hospital, Memphis, Tennessee, 38105-2794, United


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States; RecruitingWayne Lee Furman, MD 901-495-3300

Vanderbilt Children's Hospital, Nashville, Tennessee, 37232-6310, UnitedStates; RecruitingJames A. Whitlock, MD 615-936-1762

TexasBaylor College of Medicine, Houston, Texas, 77030, United States; Recruiting

C. Philip Steuber, MD 713-798-6970

CCOP - Scott and White Hospital, Temple, Texas, 76508, United States; RecruitingLucas Wong, MD 254-724-1053 [email protected]

Center for Cancer Prevention and Care at Scott and White Clinic, Temple, Texas, 76508,United States; RecruitingDick Suh, MD, PhD 254-724-9852 [email protected]

Children's Hospital of Austin, Austin, Texas, 78701, United States; RecruitingSharon K. Lockhart, MD 512-324-8480 [email protected]

Cook Children's Medical Center - Fort Worth, Fort Worth, Texas, 76104, UnitedStates; RecruitingTimothy C. Griffin, MD 682-885-4020 [email protected]

Covenant Children's Hospital, Lubbock, Texas, 79410, United States; RecruitingJohn Iacuone, MD 806-725-4840

MBCCOP - South Texas Pediatrics, San Antonio, Texas, 78229-3900, UnitedStates; RecruitingAnne-Marie Langevin, MD 210-704-3405 [email protected]

MD Anderson Cancer Center at University of Texas, Houston, Texas, 77030-4009, UnitedStates; RecruitingJoann Ater, MD 713-792-6665 [email protected]

Medical City Dallas Hospital, Dallas, Texas, 75230, United States; RecruitingCarl Lenarsky, MD 972-566-6647 [email protected]

Methodist Cancer Center at Methodist Specialty and Transplant Hospital, San Antonio,

Texas, 78229-3902, United States; RecruitingJaime Estrada, MD 210-575-8130

San Antonio Military Pediatric Cancer and Blood Disorders Center, Lackland Air ForceBase, Texas, 78236, United States; RecruitingAaron Pitney, MD 210-292-5684

Simmons Cancer Center at University of Texas Southwestern Medical Center -


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Dallas, Dallas, Texas, 75390-9063, United States; Recruiting Naomi J. Winick, MD 214-648-3074 [email protected]

Texas Tech University Health Sciences Center School of Medicine, Amarillo, Texas,79106, United States; RecruitingCurtis Wade Turner, MD 806-354-5434 [email protected]

University of Texas Health Science Center at San Antonio, San Antonio, Texas, 78207,United States; RecruitingPaul Jan Thomas, MD 210-704-3405 [email protected]

University of Texas Medical Branch, Galveston, Texas, 77555-0209, UnitedStates; RecruitingFrederick Szujuei Huang, MD 409-772-2341 [email protected]

UtahHuntsman Cancer Institute at University of Utah, Salt Lake City, Utah, 84112, United

States; RecruitingCarol S. Bruggers, MD 801-585-0303

VermontVermont Cancer Center at University of Vermont, Burlington, Vermont, 05401-3498,

United States; RecruitingAlan C. Homans, MD 802-847-2850

VirginiaCancer Center at the University of Virginia, Charlottesville, Virginia, 22908, United

States; RecruitingKimberly Dunsmore, MD 434-924-9333

Carilion Medical Center for Children at Roanoke Community Hospital, Roanoke, Virginia,24029, United States; RecruitingJoan Mistretta Fisher, MD, PhD 540-985-8055 [email protected]

Children's Hospital of the King's Daughters, Norfolk, Virginia, 23507, UnitedStates; RecruitingRebecca L. Byrd, MD 757-668-7243 [email protected]

INOVA Fairfax Hospital, Falls Church, Virginia, 22042-3300, United States; RecruitingJay N. Greenberg, MD 703-698-1110

Massey Cancer Center at Virginia Commonwealth University, Richmond, Virginia, 23298-0121, United States; Recruiting Nancy L. Dunn, MD 804-828-9605 [email protected]

Naval Medical Center, Portsmouth, Portsmouth, Virginia, 23708-5100, UnitedStates; RecruitingPaulette Charese Bryant, MD 804-398-5767


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WashingtonChildren's Hospital and Regional Medical Center - Seattle, Seattle, Washington, 98105,

United States; RecruitingDouglas Hawkins, MD 206-987-3096

Deaconess Medical Center, Spokane, Washington, 99210-0248, United States; RecruitingSteven K. Bergstrom, MD 509-473-7012 [email protected]

Fred Hutchinson Cancer Research Center, Seattle, Washington, 98109-1024, UnitedStates; RecruitingJean E. Sanders, MD 206-667-4348 [email protected]

Group Health Central Hospital, Seattle, Washington, 98112, United States; RecruitingPhilip Herzog, MD 425-883-5291

Madigan Army Medical Center, Tacoma, Washington, 98431-0001, United

States; RecruitingKelly Faucette, MD 253-968-1305 [email protected]

Mary Bridge Children's Hospital and Health Center, Tacoma, Washington, 98415-0299,United States; RecruitingWilliam J. Thomas, MD 253-403-4915 [email protected]

West VirginiaCabell Huntington Hospital, Huntington, West Virginia, 25701, United States; Recruiting

Andrew Pendleton, MD 304-691-1384 [email protected]

Mary Babb Randolph Cancer Center at West Virginia University Hospitals, Morgantown,West Virginia, 26506-9300, United States; RecruitingFrank G. Keller, MD 304-293-1217

West Virginia University - Robert C. Byrd Health Sciences Center - CharlestonDivision, Charleston, West Virginia, 25302, United States; RecruitingElizabeth M. Kurczynski, MD 304-388-1540 [email protected]

WisconsinBellin Memorial Hospital, Green Bay, Wisconsin, 54301, United States; Recruiting

Dorothy J. Ganick, MD 920-433-6025

CCOP - Marshfield Clinic Research Foundation, Marshfield, Wisconsin, 54449, UnitedStates; RecruitingTarit Kumar Banerjee, MD, FACP 715-387-5511

CCOP - St. Vincent Hospital Cancer Center, Green Bay, Green Bay, Wisconsin, 54301,United States; RecruitingThomas J. Saphner, MD 920-432-5134


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Gundersen Lutheran Cancer Center at Gundersen Lutheran Medical Center, La Crosse,Wisconsin, 54601, United States; RecruitingRobert S. Ettinger, MD 608-782-7300 [email protected]

Marshfield Clinic - Marshfield Center, Marshfield, Wisconsin, 54449-5772, UnitedStates; RecruitingHarlan James Nickerson, MD 715-387-5018

Midwest Children's Cancer Center, Milwaukee, Wisconsin, 53226, UnitedStates; RecruitingBruce M. Camitta, MD 414-456-4106

St. Vincent Hospital, Green Bay, Wisconsin, 54307-9070, United States; RecruitingJon Brandt, MD 920-433-8670

University of Wisconsin Comprehensive Cancer Center, Madison, Wisconsin, 53792-6164,United States; Recruiting

Diane Puccetti, MD 608-263-0320

Australia, New South WalesChildren's Hospital at Westmead, Westmead, New South Wales, 2145, Australia; Recruiting

Geoffrey McCowage, MD 61-2-9845-2122

Sydney Children's Hospital, Randwick, New South Wales, 2031, Australia; RecruitingGlenn Marshall, MD, MBBS 61-2-9382-1721 [email protected]

Australia, QueenslandRoyal Children's Hospital, Brisbane, Queensland, 4029, Australia; Recruiting

Liane Lockwood, MBBS, FRACP 617-363-61356 [email protected]

Australia, South AustraliaWomen's and Children's Hospital, North Adelaide, South Australia, 5006,

Australia; RecruitingMaria Louis Kirby, MBBS, FRACP 61-8-8161-7411 [email protected]

Australia, VictoriaRoyal Children's Hospital, Parkville, Victoria, 3052, Australia; Recruiting

David Ashley, MBBS, FRACP, PhD 61-39-345-5522

Australia, Western AustraliaPrincess Margaret Hospital for Children, Perth, Western Australia, 6001,

Australia; RecruitingDavid L. Baker, MD, MBBS, FRACP, FRCPA 61-8-9340-8234

Canada, AlbertaAlberta Children's Hospital, Calgary, Alberta, T2T 5C7, Canada; Recruiting

Douglas R. Strother, MD 403-943-7272


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Cross Cancer Institute, Edmonton, Alberta, T6G 1Z2, Canada; RecruitingPaul Edward Grundy, MD 780-432-8894 [email protected]

Canada, British ColumbiaBritish Columbia Children's Hospital, Vancouver, British Columbia, V6H 3V4,

Canada; RecruitingPaul C.J. Rogers, MB, ChB, FRCPC, MBA, FRCP 604-875-2322 [email protected]

Canada, ManitobaCancerCare Manitoba, Winnipeg, Manitoba, R3E 0V9, Canada; Recruiting

Rochelle A. Yanofsky, MD 204-787-4163 [email protected]

Canada, Newfoundland and LabradorJaneway Children's Health and Rehabilitation Centre, St. John's, Newfoundland and

Labrador, A1B 3V6, Canada; RecruitingJohn (Jack) Hand, MD 709-777-4799 [email protected]

Canada, Nova ScotiaIWK Health Centre, Halifax, Nova Scotia, B3J 3G9, Canada; Recruiting

Dorothy R. Barnard, MD 902-470-8291 [email protected]

Canada, OntarioChildren's Hospital of Eastern Ontario, Ottawa, Ontario, K1H 8L1, Canada; Recruiting

Jacqueline Halton, MD 613-737-7600 ext. 2370

Children's Hospital of Western Ontario, London, Ontario, N6C 2V5, Canada; RecruitingAnne Elizabeth Lois Cairney, MD 519-685-8494 [email protected]

Hospital for Sick Children, Toronto, Ontario, M5G 1X8, Canada; RecruitingAlberto S. Pappo, MD 416-813-6594 [email protected]

McMaster Children's Hospital at Hamilton Health Sciences, Hamilton, Ontario, L8N 3Z5,Canada; RecruitingRonald D. Barr, MD 905-521-2100 ext. 73464 [email protected]

Canada, QuebecCentre de Recherche du Centre Hospitalier de l'Universite Laval, Sainte-Foy, Quebec, GIV

4G2, Canada; RecruitingYvan Samson, MD 418-656-4141

Hopital Sainte Justine, Montreal, Quebec, H3T 1C5, Canada; RecruitingAlbert Moghrabi, MD 514-345-4969 [email protected]

Montreal Children's Hospital at McGill University Health Center, Montreal, Quebec, H3G1A4, Canada; RecruitingCarolyn R. Freeman, MB, BS, FRCPC 514-412-8040 [email protected]


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Canada, SaskatchewanAllan Blair Cancer Centre at Pasqua Hospital, Regina, Saskatchewan, S4T 7T1,

Canada; RecruitingChristina Ten Suan Goh, MD 306-766-2205 [email protected]

Saskatoon Cancer Centre, Saskatoon, Saskatchewan, S7N 4H4, Canada; RecruitingAli S. Kaiser, MD 306-655-2684

NetherlandsUniversity Medical Center Groningen, Groningen, 9700 RB, Netherlands; Recruiting

Willem A. Kamps, MD, PhD 31-50-361-4213 [email protected]

New ZealandStarship Children's Health, Auckland, New Zealand; Recruiting

Lochie Teague, MD 64-9-307-4949 ext. 6295 [email protected]

Puerto Rico

Puerto Rico Cancer Center at University of Puerto Rico - Medical Sciences Campus, SanJuan, 00936-5067, Puerto Rico; RecruitingNilka J. Barrios, MD 787-756-3230

San Jorge Children's Hospital, Santurce, 00912, Puerto Rico; RecruitingLuis Antonio Clavell, MD 787-726-0316 [email protected]

SwitzerlandSwiss Pediatric Oncology Group Bern, Bern, CH 3010, Switzerland; Recruiting

Annette Ridolfi-Luethy, MD 41-31-632-9372

Swiss Pediatric Oncology Group Geneva, Geneva, CH 1211, Switzerland; RecruitingPierre Wacker, MD 41-22-382-3311

Swiss Pediatric Oncology Group Lausanne, Lausanne, CH 1011, Switzerland; RecruitingMaja Beck Popovic, MD 41-21-314-3567

Donor Peripheral Stem Cell Transplantation in Treating Patients With Acute

Myeloid Leukemia, or Myeloproliferative Disorder.RATIONALE: Peripheral stem cell transplantation may be able to replace

immune cells that were destroyed by chemotherapy used to kill cancer cells.Sometimes the transplanted cells can make an immune response against the

body's normal tissues. Methotrexate and cyclosporine may prevent this fromhappening.

PURPOSE: Phase I/II trial to study the effectiveness of donor peripheral stem celltransplantation in treating patients who have acute myeloid leukemia, or myeloproliferativedisorder.Fred Hutchinson Cancer Research Center, Seattle, Washington, 98104, UnitedStates; Recruiting Ann Woolfrey, MD 206-667-4453


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XK469R in Treating Patients With Refractory Hematologic Cancer.RATIONALE: Drugs used in chemotherapy, such XK469R, work in different ways to stopcancer cells from dividing so they stop growing or die.PURPOSE: Phase I trial to study the effectiveness of XK469R in treating patients who haverefractory hematologic cancer.

IllinoisUniversity of Chicago Cancer Research Center, Chicago, Illinois, 60637-1470, United

States; RecruitingWendy Stock, MD 773-834-8982

TexasMD Anderson Cancer Center at University of Texas, Houston, Texas, 77030-4095, United

States; RecruitingFrancis J. Giles, MD 713-792-8217 [email protected]

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