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New Devices for Nutrition Tracking:Vitamins and Minerals

AMALIA GIL

Jan 28, 2019

CESO PRESENTATION

Anyone familiar with this?

[1] Canada’s Food Guide (2007)

[2] Canada’s Food Guide (2019)

Burden of NOT Meeting Food Guide

$13.8 Billion/Year

Health Care Costs

Hospital Care

Physician Care

Prescription Drugs

Indirect Costs

Loss production

Morbidity

Premature Mortality

[3] Lieffers et al. (2018)

Essential Vitamins and Minerals

Brain and Memory

B6, B12, Folic AcidEye Function

A, C, E, Lutein, Zinc

Digestion

A, B12, C, D

Heart and Blood

Iron, D, K

Bone Strength

D, K2, Calcium, Magnesium

Reproductive

B6, B12, Folic Acid

Energy Release

B12, Magnesium

Muscular System

Vitamins C, D, E

[4] Kelley, J. (2019)

Increased Risk of Chronic Disease

Type 2 Diabetes Hypertension

Ischemic Heart Failure

Pharyngeal Cancer

Kidney Disease

Stroke

Rectal Cancer

[5] Alberta Health Services (2013)

Current Tracking Method

Stage 1

Stage 2

“Assessment”

“Treatment”

Doctor’s Office

Blood Tests Results

Change in Lifestyle or Diet or Supplement

Blood Tests Results

Discussion with Doctor

Case Study - Hemoglobin

6 months 3 months

LOW

Solutions

[6-7] VitaScan.me, aminahealth.com

How it works - Technology

1. Finger prick of blood onto test strip

2. Strip placed into reader

3. Results in 10-20 min on phone or computer

Iron Level

16 ng/ml

[6] vistascan.me

How it works – Test StripLateral Flow Immunofluorescent Assay

• Flow is left to right • Fluorescently labelled antibodies• Specific affinity to the substance

[8-10] Lee et al. (2016), Lu et al. (2017)

Example – Ferritin (Iron)

Ferritin – a biomarker that is used for assessment of iron concentrations in blood

Example – Ferritin (Iron)

Example – Ferritin (Iron)

Example – Ferritin (Iron)

Example – Ferritin (Iron)

Example – Ferritin (Iron)

Example – Ferritin (Iron)

How it Works - Reader

Raspberry Pi

Fluorescence Sensor

[6] vitascan.me[9] Lu et al. (2017)

Fluorescence Sensor

Excitation LED’s

Camera Lens Regular Fluorescent[9] Lu et al. (2017)

Image Analysis

Image Processing Correlation & Display

[9] Lu et al. (2017)

Advantages

Portable System

Affordable

Fast Results Test At Home

Test on Own Terms

No Doctor’s Appointment

Required

[6] vitascan.me

Lessons Learned

• Avoid concerning users that do not need to be concerned

• Extreme care to be taken with false-positives

• Avoid overloading patients & physicians with data

[11] Sawh, M (2018)

Proposed Solution – Phone App Service

Quickly Screen High Risk Patients

At Home Tracking

Prescribe Tracker

Deficiency Diet

Chron’s Disease

Ulcerative Colitis

IBSBariatric Surgery

High Risk for Other Chronic Diseases

Physician

Patient

Rewards

Dietitian orHealth Care Coach

Provide Feedback and Recommendations

Professional

Further Assessment

Further Treatment/Testing

[6] vitascan.me

Proposed Solution – Phone App Service

Quickly Screen High Risk Patients

Physician

Deficiency Diet

Chron’s Disease

Ulcerative Colitis

IBS Bariatric Surgery

High Risk for Other Chronic Diseases

Patient

Proposed Solution – Phone App Service

Quickly Screen High Risk Patients

Physician

Deficiency Diet

Chron’s Disease

Ulcerative Colitis

IBS Bariatric Surgery

High Risk for Other Chronic Diseases

Patient

Proposed Solution – Phone App Service

Quickly Screen High Risk Patients

Physician Prescribe Tracker

Deficiency Diet

Chron’s Disease

Ulcerative Colitis

IBS Bariatric Surgery

High Risk for Other Chronic Diseases

Patient

At Home Tracking

Proposed Solution – Phone App Service

Quickly Screen High Risk Patients

Physician Prescribe Tracker

Deficiency Diet

Chron’s Disease

Ulcerative Colitis

IBS Bariatric Surgery

High Risk for Other Chronic Diseases

Patient

At Home Tracking

Proposed Solution – Phone App Service

Quickly Screen High Risk Patients

Physician Prescribe Tracker

Rewards

Deficiency Diet

Chron’s Disease

Ulcerative Colitis

IBS Bariatric Surgery

High Risk for Other Chronic Diseases

Patient

At Home Tracking

Proposed Solution – Phone App Service

Quickly Screen High Risk Patients

Physician Prescribe Tracker

Rewards

Dietitian orHealth Care Coach

Provide Feedback and Recommendations

Professional

Deficiency Diet

Chron’s Disease

Ulcerative Colitis

IBS Bariatric Surgery

High Risk for Other Chronic Diseases

Patient

At Home Tracking

Proposed Solution – Phone App Service

Quickly Screen High Risk Patients

Physician Prescribe Tracker

Rewards

Dietitian orHealth Care Coach

Provide Feedback and Recommendations

Professional

Deficiency Diet

Chron’s Disease

Ulcerative Colitis

IBS Bariatric Surgery

High Risk for Other Chronic Diseases

Patient

At Home Tracking

Proposed Solution – Phone App Service

Quickly Screen High Risk Patients

Physician Prescribe Tracker

Dietitian orHealth Care Coach

Rewards

Provide Feedback and Recommendations

Professional

Further Assessment

Deficiency Diet

Chron’s Disease

Ulcerative Colitis

IBS Bariatric Surgery

High Risk for Other Chronic Diseases

Patient

At Home Tracking

Proposed Solution – Phone App Service

Quickly Screen High Risk Patients

Physician Prescribe Tracker

Dietitian orHealth Care Coach

Provide Feedback and Recommendations

Rewards

Professional

Further Assessment

Deficiency Diet

Chron’s Disease

Ulcerative Colitis

IBS Bariatric Surgery

High Risk for Other Chronic Diseases

Patient

At Home Tracking

Proposed Solution – Phone App Service

Quickly Screen High Risk Patients

Physician Prescribe Tracker

Dietitian orHealth Care Coach

Provide Feedback and Recommendations

Rewards

Professional

Further Assessment

Further Treatment/Testing

Digital Therapeutics

[12] Cafazzo, J. (2018)

The Future

Thank you

New Devices for Nutrition Tracking:

Vitamins and Minerals

AMALIA GIL

Jan 28, 2019

CESO PRESENTATION

Questions?

References

1. Health and Welfare Canada. Eating Well with Canada’s Food Guide. [Internet]. Ottawa, Health Canada; 2007. Available from: https://www.canada.ca/content/dam/hc-sc/migration/hc-sc/fn-an/alt_formats/hpfb-dgpsa/pdf/food-guide-aliment/view_eatwell_vue_bienmang-eng.pdf

2. Canada’s Food Guide: Healthy Eating Recommendations [Internet]. Ottawa, Health Canada; 2019. Available from: https://food-guide.canada.ca/static/assets/pdf/CFG-snapshot-EN.pdf

3. Lieffers JRL, Ekwaru JP, Ohinmaa A, Veugelers PJ. The economic burden of not meeting food recommendations in Canada: The cost of doing nothing. PLoS One. 2018;13(4):1–17.

4. Kelley J. Essential Vitamins And Minerals: Sources & Functions (Infographic) [Internet]. Care Happiness. [cited 2019 Jan 1]. Available from: https://carehappiness.com/essential-vitamins-minerals-sources-functions/

5. Nutrition Guideline Vitamins and Minerals. Alberta. Alberta Health Services; 2013.

6. VitaScan [Internet]. [cited 2019 Jan 1]. Available from: https://www.vitascan.me/

7. Amina Health [Internet]. [cited 2019 Jan 1]. Available from: https://www.aminahealth.com/

References

7. Amina Health [Internet]. [cited 2019 Jan 1]. Available from: https://www.aminahealth.com/

8. Lee S, O’Dell D, Hohenstein J, Colt S, Mehta S, Erickson D. NutriPhone: A mobile platform for low-cost point-of-care quantification of Vitamin B 12 concentrations. Sci Rep. 2016;6(May):1–8. 9.

9. Lu Z, O’Dell D, Srinivasan B, Rey E, Wang R, Wang R, et al. Rapid diagnostic testing platform for iron and vitamin A deficiency. Proc Natl Acad Sci. 2017;114(51):13513–8.

10. Lu Z, O’Dell D, Srinivasan B, Rey E, Wang R, Wang R, et al. Supporting Information. Proc Natl Acad Sci. 2017;114(51):1–11.

11. Sawh M. Atrial fibrillation explained: Why Apple want to look after your heart [Internet]. Wearable LTD. 2018 [cited 2019 Jan 1]. Available from: https://www.wareable.com/fitbit/atrial-fibrillation-explained-4220

12. Cafazzo J. Implementing Human Factors in Healthcare. 2018.