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Using Ovid® for Meta-Analysis & Systematic ReviewsChris Jung정민우Wolters Kluwer Health – Ovid 한국지사대표

Agenda

2Using Ovid® for Meta-Analysis & Systematic Reviews

1. Preparing for a Systematic Review

2. Ovid® MEDLINE vs. PubMed Content Platform Features Search Functionality Results Management Multiple Database Searching &

Deduplication

3. Structured Search Example

4. Ovid REMINER

3Ovid® MEDLINE PsycINFO・ 講習会

Preparing for a Systematic Review

Creating a Systematic Review

4Using Ovid® for Meta-Analysis & Systematic Reviews

Source: http://navigatingeffectivetreatments.org.au/

➂ Update, as required

Search

Meta-Analyse

Determining the question

5Using Ovid® for Meta-Analysis & Systematic Reviews

The PICO process is a technique used in evidence based practice to answer a clinical question PICO is an acronym for: Population, Intervention,

Comparison, Outcome

Source: Macquarie University Library, Libguides: http://libguides.mq.edu.au/content.php?pid=371659&sid=3291432

Defining a question

6Using Ovid® for Meta-Analysis & Systematic Reviews

Among Type 2 diabetic patients, do improved lifestyle habitsaffect HbAlc levels?

P Type 2 diabetic patients

I improved lifestyle habits

C HbAlc levels without improved lifestyle habits

O changes in HbAlc levels

Search for relevant data

7Using Ovid® for Meta-Analysis & Systematic Reviews

Cochrane collaboration recommends searching in Cochrane Central Register of Controlled Trials, Medline and Embase.

Search for relevant data

8Using Ovid® for Meta-Analysis & Systematic Reviews

SHKW

SHKW

SH

KWSH

KW

Topical lidocaine for neuropathic pain in adults,Cochrane Database of Systematic Reviews, Volume (6), 2016.

SH: Subject HeadingsKW: Keywords

Methodological limits• RCT and CCT (.pt)• Studies about drug therapy

Ovid®マルチファイル検索・上級検索モード

9Ovid® MEDLINE PsycINFO・ 講習会

Ovid® MEDLINE vs. PubMed

Introduction to MEDLINE on Ovid®

10Using Ovid® for Meta-Analysis & Systematic Reviews

Database Creation

MEDLINE In Process Segments

MEDLINE SegmentEpub Ahead of Print

Publisher Submitted

MEDLINE In Process

Pubmed Not MEDLINE

In Data Review

MEDLINE In Process MEDLINE

PubMed Search Page & Ovid®

11Using Ovid® for Meta-Analysis & Systematic Reviews

Advanced Search, Search Fields &

MultiField Search

Find Citation

Clinical Queries

Mapping and Search Tools

PubMed Search Page & Ovid®

12Using Ovid® for Meta-Analysis & Systematic Reviews

Find Citation

Clinical Queries

Mapping and Search Tools

Advanced Search, Search Fields & Multi-Field

Search

PubMed Search – automatic explode

13Using Ovid® for Meta-Analysis & Systematic Reviews

Ovid® MEDLINE Search – mapping process

14Using Ovid® for Meta-Analysis & Systematic Reviews

Explode –include all narrower

terms

Focus – find records where

this is the main concept

Ovid® MEDLINE Search – mapping process

15Using Ovid® for Meta-Analysis & Systematic Reviews

Export Options

16Using Ovid® for Meta-Analysis & Systematic Reviews

Text file or CSV Select all results

or a range

My NCBI vs.My Projects

17Using Ovid® for Meta-Analysis & Systematic Reviews

Add sub-foldersSearch all or selected projects

Collaborate with Annotations

Send Auto-Alert results directly to a project folder

Search multiple databases with deduplication

18Using Ovid® for Meta-Analysis & Systematic Reviews

Search multiple databases with deduplication

19Using Ovid® for Meta-Analysis & Systematic Reviews

Multiple database results combined, ranked by

relevancy (Basic Search) or chronological order (Advanced Search)

Filter results display by database

20Ovid® MEDLINE PsycINFO・ 講習会

Structured Search Example

StructuredSearching in Ovid®

21Using Ovid® for Meta-Analysis & Systematic Reviews

Among Type 2 diabetic patients, do improved lifestyle habits affect HbAlc levels?

Type 2 diabetes lifestyle HbAlc

Among Type 2 diabetic patients, do improved lifestyle habitsaffect HBAlc levels?

HLA PD Day

http://access.ovid.com/training/pico/english/pico_widget.htm

Structured Searching in Ovid®

24Using Ovid® for Meta-Analysis & Systematic Reviews

Map keywords to controlled Terms

Structured Searching in Ovid®

25Using Ovid® for Meta-Analysis & Systematic Reviews

Click on the scope note to see more

information about the subject heading

Structured Searching in Ovid®

26Using Ovid® for Meta-Analysis & Systematic Reviews

(diabetes adj2 (adult onset OR ketotis resistant OR maturity onset OR non?insulin dependent OR slow

onset OR stable OR type?2 OR type?ii)) OR mody OR niddm

Adjacency operator (searches for words

based on their proximity)

Truncation inside a word (stands for any

letter or nothing)

Structured Searching in Ovid®

27Using Ovid® for Meta-Analysis & Systematic Reviews

Click on the subject heading to

view the full thesaurus

Structured Searching in Ovid®

28Using Ovid® for Meta-Analysis & Systematic Reviews

Select ‘Explode’ to search the

narrower terms together with the

main term

Structured Searching in Ovid®

29Using Ovid® for Meta-Analysis & Systematic Reviews

Select a subheading to

refine the search to a specific

aspect of the controlled term, or leave blank to

perform a general search

Choose the Therapy subheading to limit results

to records indexed with the Therapy aspect of

Diabetes Mellitus, Type 2

Structured Searching in Ovid®

30Using Ovid® for Meta-Analysis & Systematic Reviews

‘exp’ means ‘explode’ (the search includes the narrower

terms as well as the main term)

‘/’ means this is a subject heading

‘[ ]’ contains the specified subheading(s)

Structured Searching in Ovid®

31Using Ovid® for Meta-Analysis & Systematic Reviews

Deselect ‘Map Term to Subject Heading’ for

keyword search

Structured Searching in Ovid®

32Using Ovid® for Meta-Analysis & Systematic Reviews

Select sets and combine with ‘AND’ or ‘OR’

StructuredSearching in Ovid®

33Using Ovid® for Meta-Analysis & Systematic Reviews

Among Type 2 diabetic patients, do improved lifestyle habits affect HbAlc levels?

Type 2 diabetes lifestyle HbAlc

Among Type 2 diabetic patients, do improved lifestyle habitsaffect HBAlc levels?

exp Diabetes Mellitus, Type 2/

((diabetes adj2 (adult onset OR ketotis resistant OR maturity onset OR non?insulindependent OR slow onset OR stable OR type?2 OR type?ii)) OR mody OR niddm)

Structured Searching in Ovid®

34Using Ovid® for Meta-Analysis & Systematic Reviews

Structured Searching in Ovid®

35Using Ovid® for Meta-Analysis & Systematic Reviews

Structured Searching in Ovid®

36Using Ovid® for Meta-Analysis & Systematic Reviews

life?style*

Right-side Truncation (search for all words

beginning with certain letters)

Structured Searching in Ovid®

37Using Ovid® for Meta-Analysis & Systematic Reviews

Structured Searching in Ovid®

38Using Ovid® for Meta-Analysis & Systematic Reviews

Structured Searching in Ovid®

39Using Ovid® for Meta-Analysis & Systematic Reviews

Structured Searching in Ovid®

40Using Ovid® for Meta-Analysis & Systematic Reviews

Structured Searching in Ovid®

41Using Ovid® for Meta-Analysis & Systematic Reviews

StructuredSearching in Ovid®

42Using Ovid® for Meta-Analysis & Systematic Reviews

Among Type 2 diabetic patients, do improved lifestyle habits affect HbAlc levels?

Type 2 diabetes lifestyle HbAlc

Among Type 2 diabetic patients, do improved lifestyle habitsaffect HBAlc levels?

exp Diabetes Mellitus, Type 2/

exp Life Style/

life?style*

((diabetes adj2 (adult onset OR ketotis resistant OR maturity onset OR non?insulindependent OR slow onset OR stable OR type?2 OR type?ii)) OR mody OR niddm)

Structured Searching in Ovid®

43Using Ovid® for Meta-Analysis & Systematic Reviews

What you do select when searching?

Structured Searching in Ovid®

44Using Ovid® for Meta-Analysis & Systematic Reviews

Where you do you click first?

Structured Searching in Ovid®

45Using Ovid® for Meta-Analysis & Systematic Reviews

hb?a1* OR (a1* adj1 (h?emoglobin* adj1 glycosylated)) OR (glycated adj1 h?emoglobin*) OR

(glycoh?emoglobin a) OR (glycosylated a1* adj1 h?emoglobin*) OR (glycosylated h?emoglobin*) OR

(h?emoglobin* adj1 a1*)

Structured Searching in Ovid®

46Using Ovid® for Meta-Analysis & Systematic Reviews

Where you do you click next?

Structured Searching in Ovid®

47Using Ovid® for Meta-Analysis & Systematic Reviews

Where you do check?

Structured Searching in Ovid®

48Using Ovid® for Meta-Analysis & Systematic Reviews

Structured Searching in Ovid®

49Using Ovid® for Meta-Analysis & Systematic Reviews

What you do de-select when

searching?

Structured Searching in Ovid®

50Using Ovid® for Meta-Analysis & Systematic Reviews

How do you combine the

searches?

StructuredSearching in Ovid®

51Using Ovid® for Meta-Analysis & Systematic Reviews

Among Type 2 diabetic patients, do improved lifestyle habits affect HbAlc levels?

Type 2 diabetes lifestyle HbAlc

Among Type 2 diabetic patients, do improved lifestyle habitsaffect HBAlc levels?

exp Diabetes Mellitus, Type 2/

exp Life Style/

life?style*

((diabetes adj2 (adult onset OR ketotis resistant OR maturity onset OR non?insulindependent OR slow onset OR stable OR type?2 OR type?ii)) OR mody OR niddm)

hb?a1* OR (a1* adj1 (h?emoglobin* adj1 glycosylated)) OR (glycated adj1 h?emoglobin*) OR (glycoh?emoglobin a) OR (glycosylated a1* adj1 h?emoglobin*) OR (glycosylated h?emoglobin*) OR (h?emoglobin* adj1 a1*)

exp Hemoglobin A, Glycosylated/

Structured Searching in Ovid®

52Using Ovid® for Meta-Analysis & Systematic Reviews

Final set – combine 3 subsets with ‘AND’

Structured Searching in Ovid®

53Using Ovid® for Meta-Analysis & Systematic Reviews

Structured Searching in Ovid®

54Using Ovid® for Meta-Analysis & Systematic Reviews

Clinical Queries - Limit to types of studies

Structured Searching in Ovid®

55Using Ovid® for Meta-Analysis & Systematic Reviews

StructuredSearching in Ovid®

56Using Ovid® for Meta-Analysis & Systematic Reviews

Among Type 2 diabetic patients, do improved lifestyle habits affect HbAlc levels?

Type 2 diabetes lifestyle HbAlc

Among Type 2 diabetic patients, do improved lifestyle habitsaffect HBAlc levels?

exp Diabetes Mellitus, Type 2/

exp Life Style/

life?style*

((diabetes adj2 (adult onset OR ketotis resistant OR maturity onset OR non?insulindependent OR slow onset OR stable OR type?2 OR type?ii)) OR mody OR niddm)

hb?a1* OR (a1* adj1 (h?emoglobin* adj1 glycosylated)) OR (glycated adj1 h?emoglobin*) OR (glycoh?emoglobin a) OR (glycosylated a1* adj1 h?emoglobin*) OR (glycosylated h?emoglobin*) OR (h?emoglobin* adj1 a1*)

exp Hemoglobin A, Glycosylated/

middle aged(45 years plus)

Clinical Queries:therapy (best balanceof sensitivity andspecificity

Structured Searching in Ovid®

57Using Ovid® for Meta-Analysis & Systematic Reviews

Save results in a Project folder

Meta-Analysis: Extraction of relevant data

58Using Ovid® for Meta-Analysis & Systematic Reviews

Source: http://training.cochrane.org/

Meta-Analysis: Analyze and combine the data

59Using Ovid® for Meta-Analysis & Systematic Reviews

Source: http://support.sas.com/kb/35/addl/fusion_35143_1_forestplot_2col.gif

Auto-Alerts – keep track of new research

60Using Ovid® for Meta-Analysis & Systematic Reviews

Auto-Alerts – keep track of new research

61Using Ovid® for Meta-Analysis & Systematic Reviews

Automatically run search

when database is

updated

Receive results via email and

deliver directly to a

project folder

Ovid REMINER

62Using Ovid® for Meta-Analysis & Systematic Reviews

Use REMINER…• If you have a collection of references from a database, or

another source, and want to find more of the same type of article, or set up an alert…

• If you have a structured Ovid search strategy based on mapping and search tools, and want to add a reliable set of keywords to broaden out your search…

• If you want to turn a gold standard list of references into a search filter for your library clients…

• If you want to explore the characteristics of the references which were used to produce a systematic review – identify similarities – subjects, authors, etc…

Ovid REMINER

63Using Ovid® for Meta-Analysis & Systematic Reviews

Export target records

Ovid REMINER

64Using Ovid® for Meta-Analysis & Systematic Reviews

Export as an ‘Excel Sheet’

and select desired fields (ab, sh, ti, ui/an, etc)

Ovid REMINER

65Using Ovid® for Meta-Analysis & Systematic Reviews

Convert into .xlsx file format and confirm desired fields from selected database

Ovid REMINER

66Using Ovid® for Meta-Analysis & Systematic Reviews

Upload the .xlsx file and ‘Submit Query’

http://tools.ovid.com/REMINER/

Ovid REMINER

67Using Ovid® for Meta-Analysis & Systematic Reviews

Select required fields and words and

phrases from the terms list to include in your search. Edit

as desired.

Ovid REMINER

68Using Ovid® for Meta-Analysis & Systematic Reviews

Confirm for sensitivity vs. specificity

Sensitivity = 23/93or 24.7% of Gold Standard Set

Ovid REMINER

69Using Ovid® for Meta-Analysis & Systematic Reviews

Review Gold Standard

references or references not

included in search results for key subjects and

confirm via scope notes

Ovid REMINER

70Using Ovid® for Meta-Analysis & Systematic Reviews

Edit the search to fit intention (sensitivity vs.

specificity), and Run Search

Ovid REMINER

71Using Ovid® for Meta-Analysis & Systematic Reviews

Export a record from in Word format, and include the

Search History

Confirm for sensitivity vs. specificity

Sensitivity = 93/93or 100% of Gold Standard Set

Review results

Ovid REMINER

72Using Ovid® for Meta-Analysis & Systematic Reviews

Copy the whole search

statement

Creating a Search Link

73Using Ovid® for Meta-Analysis & Systematic Reviews

Input the required information and paste the whole

search statement

Use the Search Link, as desired

http://demo.ovid.com/demo/search_link/search_link.htm

How to learn more

74Using Ovid® for Meta-Analysis & Systematic Reviews

Ovid Resource Center: resourcecenter.ovid.com

How to learn more

75Using Ovid® for Meta-Analysis & Systematic Reviews

PICO Resource Center: access.ovid/com/training/pico/english

How to learn more

76Using Ovid® for Meta-Analysis & Systematic Reviews

Ovid Expert Searches: http://resourcecenter.ovid.com/site/resources/expert_search/healthexp.html

Ovid REMINER:

http://tools.ovid.com/REMINER/

Filter Link Builder:

http://demo.ovid.com/demo/search_link/search_link.htm

Ovid Database Shortnames:

http://www.ovid.com/site/support/tech_support.jsp#tabs5

Widget Builder:

http://tools.ovid.com/widget/

Flinders Filters Smart Searching: Logical Steps to Building and Testing your LiteratureSearch:

https://sites.google.com/site/smartsearchinglogical/home

How to learn more

77Using Ovid® for Meta-Analysis & Systematic Reviews

support@ovid.com

Using Ovid® for Meta-Analysis & Systematic ReviewsChris JungRegional Sales Manager, South Korea

2016

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