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UpdatedMarch15,2019

SCOPE

TheJournalofProsthodonticspromotestheadvancedstudy,science,andpracticeofprosthodontics,implant,esthetic,andreconstructivedentistry.ItistheofficialjournaloftheAmericanCollegeofProsthodontists,theassociationthatrepresentsthedentalspecialtyofprosthodontics.TheJournalofProsthodonticsservesbothresearchersandpracticingcliniciansbyprovidingaforumforthepresentationanddiscussionofevidence-basedprosthodonticresearch,treatmentconcepts,techniques,andprocedures.TheobjectiveoftheJournalofProsthodonticsistofacilitatetheeffectiveworldwidetransmissionofnewandinnovativeprosthodontic-relatedresearchandknowledge.Thejournalpublishesoriginalscientificarticlespresentinginformationthatisnewandrelevanttoprosthodontics.Additionally,itpublishesreportsofinnovativetechniquesandclinicaltreatments,systematicreviewsoftopicsofinteresttothefieldofprosthodontics,reviewsofnewinstrumentationandproducts,newusesforexistingmaterial,digitaltechnologyadvancesrelatedtoprosthodontics,instructiveclinicalreports,editorials,andannouncementsofimportancetotheprosthodonticcommunity.

EDITOR-IN-CHIEFRadiMasri,DDS,MS,PhD,FACPUniversityofMarylandSchoolofDentistryrmasri@umaryland.edu

ASSOCIATEEDITOR-IN-CHIEFSharonC.Siegel,DDS,MS,MBANovaSoutheasternUniversityCollegeofDentalMedicinescsiegel@nova.edu

MANAGINGEDITORAletheaB.Gerding,MAAmericanCollegeofProsthodontistsagerding@prosthodontics.org

Submitathttps://mc.manuscriptcentral.com/jopr

UpdatedMarch15,2019

TABLEOFCONTENTSARTICLETYPES 3MANUSCRIPTPREPARATION 4Organizationandbasicformatting 4Fileformatsaccepted 5Titlepage 5Abstract 5Text 5Styleandformatting 6Editorialassistancefornon-Englishspeakingauthors 7Citations/References 8Tables 8Artwork/Figures 10Imagemanipulation/ethicalguidelines 11MANUSCRIPTSUBMISSIONANDREVIEW 12Peerreviewprocess 12Submittingarevision 12Rebuttals 13MANUSCRIPTPUBLICATION(AFTERACCEPTANCE) 13Coststoauthors 13Openaccessandcopyright 14Depositiontorepositories 14Onlinepublicationandproofreading 14ETHICALPOLICIES 15Datasharingandbioethics 15Reportingguidelines 17Conflictsofinterest 17Authorship 17Plagiarism 18Retractionpolicy 19Correctionspolicy 19APPENDICESAppendixA:Releaseformforpatientimages 20AppendixB:Manuscriptsubmissionchecklist 21AppendixC:Responsetoreviewertemplate(forrevisions) 24

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ARTICLETYPESACCEPTED

Articletype

Description Abstracttype References Figuresandtables

TotalWordpages*

Researcharticles

Presentoriginalresearch,invivoorinvitro

Structured:Purpose/Materials&Methods/Results/Conclusions

Nolimit8 10

Clinicalreports

Reportofthepresentation,treatment,andfollow-upofanindividualpatient

Non-structured 30 10 10

Techniquearticles

Describesasolutiontoaparticulartechnicalprobleminclinicaldentistry,inastep-by-stepformat

Non-structured 20 10 10

LetterstotheEditor**

Reportoriginaldata,discusspublishedarticles,orpresenthypotheses

Nonerequired 15 24

ReviewsSystematicreviewspreferred,contacttheeditorpriortosubmittinganon-systematicreview

Structured:Purpose/Methods/Results/Conclusions

Nolimit7

Nolimit

*Textonly(pagecountdoesnotincludetitle,references,tables,orfigures)

**LettertoEditorpolicy:

Whilewewillreadandrespondtoallletters,wewillonlypublishaselectfew.Wearemostlikelytopublishlettersthatdealwithacontroversialtopic,advocateforthefieldofprosthodontics,orthattakeissuewithresearchpublishedintheJournalofProsthodontics.Whilealettermaybecritical,inordertobeconsideredforpublication,itmustnotbeinsulting.

UpdatedMarch15,2019

Criticismshouldbeconstructive,andargumentsmadeshouldbeappropriatelyreferencedtopreviouslypublishedwork.

Uponapprovalforpublication,wewillpublishtheletterinthenextavailableprintissueoftheJournalofProsthodontics.WhenwritteninresponsetoanarticlepublishedintheJournal,wewillalsogivetheauthoroftheoriginalarticletheopportunitytorespond.Iftheychoosetodoso,wewillattempttopublishtheletterandresponseinthesameissue.

MANUSCRIPTPREPARATION

Organizationandbasicformattingofthemanuscript

Element Description

Font 12-point,TimesNewRomanor10-point,Arial

Linespacing Double-spacedthroughout

Margins Oneinch(2.5cm)

Pagesize Letter(8½x11)inches

Pagenumbers Yes;startwiththetitlepageaspage1,placeonlowerright-handcorner

Linenumbers Donotuse

Requiredlayout Forresearchmanuscriptsandreviews:Titlepage(includingconflictofinterestdeclaration),Abstract,Introduction,Materials&Methods,Results,Discussion,Conclusions,Acknowledgements,References,Tables,FiguresandFigureLegends,SupplementaryMaterial

ForClinicalReports/Techniquearticles:Titlepage,Abstract,Introduction,ClinicalReport(orTechnique),Discussion,Conclusion/Summary,Acknowledgements,References,Tables,FiguresandFigureLegends,SupplementaryMaterial

(detailsbelow)Headingstyle Firstlevel:allcaps,bold;Secondlevel:Sentencecase,boldanditalics;Third

level:Sentencecase,italics;Fourthlevel:Notrecommended.

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Fileformatsaccepted

Coverletter .doc,.docx,.pdfManuscriptbody .doc,.docxTables .doc,.docxFigures preferred: .tiff,.eps,.pdfVideos .mp4,.mov

Titlepage

Thetitlepageshouldcontainthefollowinginformationintheordergiven:

1) Fulltitleofmanuscript2) Arunningtitle,notexceeding60lettersandspaces3) Authors'fullnamesandauthors’degreesandhonorifics(i.e.,DDS,MSc,PhD,FACP,etc.)4) Authors'institutionalaffiliationsincludingcityandstate(USauthors)orcityandcountry

(non-USauthors)5) Thename,address,ande-mailaddressoftheauthorresponsibleforcorrespondence

aboutthemanuscript6) Iftheworkhaspreviouslybeenpresented,thename,place,anddateofmeeting(s)7) Ifanyfinancialsupportwasreceived,thegrant/contractnumber,sponsorname,and

city,state,andcountrylocationmustbesupplied.Theinformationwillbedisclosedinthepublishedarticle.

8) Ifanyauthorhasaconflictofinterest,itshouldbereported.Theseinclude,forexample,patent,ownership,employment,stockownership,consultancies,orspeaker'sfee.

Abstractpage

Anabstractisrequiredforallmanuscripts,withtheexceptionofletterstotheeditor,andmustprecedethebodyofthemanuscript.Abbreviationsandreferencesshouldnotappearintheabstract.Researchmanuscriptsmustconformtothestructuredabstractformat(seeabove).ClinicalreportsandTechniquemanuscriptsdonotneedastructuredabstract.Followingtheabstractandonthesamepage,thereshouldbeseveralwordsnotappearinginthetitleofthemanuscripttobetitled:KEYWORDS.

Text

Researchmanuscriptsshouldincludethefollowingsections:Introduction,MaterialsandMethods,Results,Discussion,Conclusion,Acknowledgements,andReferences.Other

manuscriptsshouldbeginwithtwotofiveintroductoryparagraphs.Theremainderofthemanuscriptshouldbedividedintosectionsprecededbyappropriateheadings(i.e.,“Clinicalreport,”“Technique,”etc.).

TheIntroductionwillincludethefollowing:adescriptionoftheproblemthatinspiredthestudyandwhatdistinguishesitfrompreviousresearchthatinvestigatedthesameproblem;abriefdiscussionofrelevantpublishedmaterialthataddressedthesameproblemorthatdocumentsmethodologyusedinthestudy;andthegoalofthestudy,thepurposestatementandnullhypothesis.

TheMaterialsandMethodssectiondescribesmaterialsorsubjectsusedandthemethodsselectedtoevaluatethem,includinginformationabouttheoveralldesign,thenatureofthesamplestudied,samplesize,thetypeofinterventions(ortreatments)appliedtotheindividualelementsinthesample,andtheprincipaloutcomemeasure.Statisticalmethodologyandrationaleforsamplesizedeterminationmustbeincludedinthissection.Pleasenote:Allhumansubjectresearch(includingsurveys)mustincludeastatementofethicalorinstitutionalreviewboardapproval.

TheJournalofProsthodonticsencouragesauthorstoregisterclinicaltrialspriortosubmissionatoneoftheregistrationsiteslistedbelow.TheregistrationnumberanddateofregistrationshouldbeincludedintheMaterialsandMethodssection.See“Reportingguidelines”onpage17belowforfurtherdetails.

TheResultssectionwillbeaclearstatementofthefindingsandanevaluationoftheirvaliditybasedontheoutcomeofstatisticaltests.Whenreportingresultsofstatisticaltests,actualpvaluesmustbereported.

TheDiscussionsectionpresentstheresearchinitsbroadercontext,describesitsclinicalimplications,identifieslimitationsorproblemsthatemergedduringthecourseofthestudy,characterizesthelargersignificanceofthefindings,andarticulatesanyfurtherquestionsremainingtobeansweredonthesubject.

TheConclusionsectionincludesonlyabriefandsuccinctsummaryofthefindings.

AnAcknowledgementsectiontothankanyonewhocontributedtothemanuscript,butisnotalistedauthor(i.e.,statistician,copyeditor,dentaltechnician,photographer,artist).

NotesonJournalofProsthodonticsstyleandformattingofthetext

AuthorsaretousecurrentprosthodonticnomenclatureandarereferredtotheGlossaryofProsthodonticTerms(9thEdition)foracceptedterminology.

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Whenatradenamemustbeused,citeparentheticallythetradenameandthename,city,state(UScompanies)orcityandcountry(non-UScompanies)ofthemanufacturer.Examples:(CEREC4.4Software;DentsplySirona,York,PA);(IPSe.maxPressHTingots,A2shade;IvoclarVivadent,Schaan,Liechtenstein)

Measurementsshouldbeinthemetricsystem.

Usethesymbol×ratherthantheletterxasamultiplicationsign.

ReporttheactualPvaluesto3decimalplaces.ForPvaluesbelow0.001write<0.001.

Reportresultsto2decimalplaces.

Whenreportingdatawiththe±sign,pleaseusethespacing123.45±6.78µm.

Donotitalicizeforeignwordssuchas"invivo"or"invitro"

Usedigitsformostnumbersappearingwithinthetext,exceptatthestartofasentence,andwhentheuseofthedigitplacesunnecessaryemphasisonthenumber;orwhen"one"isusedasapronoun.

Minimizetheuseofsubheadingsinthetext.

Editorialassistancetonon-nativeEnglishspeakers

IfEnglishisnotyournativelanguage,wesuggestyouhaveanativeEnglishspeakerreadandreviewthemanuscriptpriortosubmission.AnEnglish-speakingcolleaguecanbeanexcellentresource.Ifyoudonotknowsomeonewhocanhelpyou,werecommendthatyouhaveyourpaperprofessionallyeditedforEnglishlanguagebyaservicesuchasWileyPublishing’sathttp://wileyeditingservices.com.

AmericanJournalExpertsalsoprovidehighqualityediting:https://www.aje.com/en/services/editing

Pleasenotethatwhilethisservicewillgreatlyimprovethereadabilityofyourpaper,itdoesnotguaranteeacceptanceofyourpaperbythejournal.

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Citations and references

Numberreferencesconsecutivelyintheorderinwhichtheyarefirstmentionedinthetext.Identifyreferencesintexts,tables,andlegendsbysuperscriptArabicnumerals.Usethestyleoftheexamplesbelow,whicharebasedontheformatusedbytheUSNationalLibraryofMedicineinIndexMedicus.Forabbreviationsofjournals,consultthe'ListoftheJournalsIndexed'printedannuallyintheJanuaryissueofIndexMedicus.Referencenumbersshouldappearafterpunctuationmarks,notbefore.Example:Todate,zirconiadentalceramicshavehadanexcellentclinicalperformancewithacumulative5-yearsurvivalrateof92.1%forzirconia-basedall-ceramicsinglecrowns,1and90.4%fortooth-supportedfixeddentalprostheses.2

Articletype Example

Journalarticle FernandezMA,NimmoA,Behar-HorensteinLS:Digitaldenturefabricationinpre-andpostdoctoraleducation:AsurveyofUSdentalschools.JProsthodont2016;25:83-90

Journalarticle,4ormoreauthors

RodriguezLS,PaleariAG,GiroG,etal:Chemicalcharacterizationandflexuralstrengthofadenturebaseacrylicresinwithmonomer2-tert-butylaminoethylmethacrylate.JProsthodont2013;22:292-297

Book AnusaviceKJ,ShenC,RawlsHR(eds):Phillips'ScienceofDentalMaterials(ed12).Philadelphia,Saunders,2013

Chapterinabook PhoenixRD:Denturebaseresins:Technicalconsiderationsandprocessingtechniques,inAnusaviceKJ(ed):Phillips’ScienceofDentalMaterials,vol1(ed10).Philadelphia,Saunders,1996,pp237-271

MastersorPhDThesis

SmithJ:MarginalvaluesofCAD/CAMceramics[dissertation].Boston,HarvardSchoolofDentalMedicine,1995

Website eHumanDigitalAnatomy:https://ehuman.com/.Accessed2/12/19

Tables

Tablesshouldbepositionedfollowingthereferences,notinthebodyofthemanuscript.ThetablesshouldbenumberedconsecutivelywithArabicnumerals.Eachtableshouldbetypedon

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aseparatesheet.Includeanynecessarylegendsonthesamepagewiththeassociatedtable.Donotsubmittablesasimagefiles.Tablesshouldbeprovidedinasimpleform,withoutstyleformattingandwithoutuseofcolor

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Artwork/figures

ThetablebelowdetailstypicalimagesacceptedbytheJournalofProsthodontics.Figuresshouldbesubmittedafterthetables(ifincluded)orafterthereferencelist(iftablesnotincluded),notinthebodyofthetext.

Clinicalimage Lineart CombinationExample

Resolution 300dpi+ 1200dpipreferred,300+dpiaccepted 600dpipreferred,300+dpiaccepted

Size 3x5inchesminimum 3x5inchesminimum 3x5inchesminimumFileformat tiff,eps,orpdfpreferred tiff,eps,orpdfpreferred tiff,eps,orpdfpreferredNotes GuidelinesapplytoSEMimagesaswell Forbargraphs,blackandwhiteimages

preferredIncludepaneledimagesinoneimagefile(i.e.,donotsubmitFigure1AandFigure1Basseparatefiles).

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Imagemanipulationandethicalguidelines

Photographsofpeople:TheJournalofProsthodonticsfollowscurrentHIPAAguidelinesfortheprotectionofpatient/subjectprivacy.Ifanindividualpicturedinadigitalimageorphotographcanbeidentified,hisorherpermissionisrequiredtopublishtheimage.ThecorrespondingauthormaysubmitalettersignedbythepatientauthorizingtheJournalofProsthodonticstopublishtheimage/photo.Or,aformprovidedbytheJournalofProsthodontics(AppendixAbelow)maybedownloadedforyouruse.ThisapprovalmustbereceivedbytheEditorialOfficepriortofinalacceptanceofthemanuscriptforpublication.Otherwise,theimage/photomustbealteredsuchthattheindividualcannotbeidentified(blackbarsovereyes,etc).

Manipulationofdigitalphotos:AuthorsshouldbeawarethattheJournalconsidersdigitalimagestobedata.Hence,digitalimagessubmittedshouldcontainthesamedataastheoriginalimagecaptured.AnymanipulationusinggraphicalsoftwareshouldbeidentifiedineithertheMethodssectionorthecaptionofthephotoitself.Identificationofmanipulationshouldincludeboththenameofthesoftwareandthetechniquesusedtoenhanceorchangethegraphicinanyway.Suchadisclaimerensuresthatthemethodsarerepeatableandensuresthescientificintegrityofthework.

Nospecificfeaturewithinanimagemaybeenhanced,obscured,moved,removed,orintroduced.ThegroupingofimagesfromdifferentSEMs,differentteeth,orthemouthsofdifferentpatientsmustbemadeexplicitbythearrangementofthefigure(i.e.,byusingdividinglines)andinthetextofthefigurelegend.Adjustmentsofbrightness,contrast,orcolorbalanceareacceptableonlyiftheyareappliedtothewholeimage,andaslongastheydonotobscure,eliminate,ormisrepresentanyinformationpresentintheoriginal,includingbackgrounds.

Theremovalofartifactsoranynon-integraldataheldintheimageisnotallowed.Forinstance,removalofpapillaeor“cleaningup”ofsalivabubblesisnotallowed.

Casesofdeliberatemisrepresentationofdatawillresultinrejectionofamanuscript,orifthemisrepresentationisdiscoveredafteramanuscript’sacceptance,revocationofacceptance,andtheincidentwillbereportedtothecorrespondingauthor'shomeinstitutionorfundingagency.

Copyrightpermissions:Anyillustrationsortablesthathavebeenpublishedpreviouslymustbeaccompaniedbyaletterofpermissionfromthecopyrightholder(usuallythepublisher).Illustrationsortablesthathavebeenadaptedormodifiedmustalsobeaccompaniedbylettersofpermission.

UpdatedMarch15,2019

MANUSCRIPTSUBMISSIONANDREVIEW

Whenyouarereadytosubmityourmanuscript,thefilescanbeuploadedthroughoursubmissionandreviewwebsite:https://mc.manuscriptcentral.com/jopr

AchecklistofmanuscriptrequirementsinprovidedinAppendixBbelow.Thisisahelpfulguidetoreviewpriortosubmittingyourmanuscript.

Peerreviewprocessandreviewerrecommendations

AllmanuscriptswillbeassessedbytheEditor-in-Chief,and,ifappropriate,willbesenttoanassistanteditorandtwoormoreexternalreviewers.Manuscriptsthatarenotreviewedwillbereturnedtotheauthors.Manuscriptswillbereviewedforcontent,originality,importancetothefield,appropriatenessofstatisticalanalysis,andderivationofconclusions.AuthorsshouldnotethatmanuscriptsmaybereturnedafterinitialreviewbytheeditorialofficeifthepaperisdeemedunlikelytobereviewedfavorablybyvirtueofinsufficientinterestfortheJournalofProsthodonticsreadership.Thisrapidrejectionprocessenablestheauthortopromptlysubmitforpublicationelsewhere.Ifsentforreview,theoutcomemaybeacceptancewithorwithoutrevisions,non-acceptancewithanopportunitytomakerevisionsforresubmission,orrejection.Manuscriptsbeingrevisedbytheauthorswillbeheldbytheeditorialofficeforamaximumof90days,afterwhichanewsubmissionisrequired.Pleasecontacttheeditorialofficeifyouarenotabletomakethisdeadline.

Submittingarevision

Dependingonthenumberofrevisionsrequested,revisionswillbereturnedtotheoriginalreviewersortheeditorswillconductthereview.Newreviewerswillbeenlistedatthediscretionoftheeditor.Notallrevisedmanuscriptswillbeaccepted.Withrareexception,theJournalofProsthodonticswillnotreviewmorethan3revisionsofthesamemanuscript.

Allchangesmadeinarevisedmanuscriptmustbeannotatedviahighlightordifferentfontcolor.Thiswillhelpreviewerslocatethechangesthatcorrespondwithyourpoint-by-pointresponse.DonotusetheTrackChangesfeatureofWordtomarkyourchanges,asthisoftenmakesmanuscriptsdifficultforreviewersandeditorstoread.Pleasenoteinyourcoverletterifthechangesaresoextensive(i.e.,morethan75%ofthedocument)thatitwouldbeunreasonabletoannotatethechanges.

Responsestoreviewersandeditorsshouldbeincludedasatext(.docor.docx)filewiththemanuscriptfilesandnamedresponsetoreviewers.AtemplatetouseasaguideisprovidedinAppendixC.

RebuttalsOnrareoccasions,editorialdecisionsmaybere-considered.Authorswithseriousconcernsaboutpotentialscientificerrorsinthereviewprocessmaysendarebuttallettertotheeditor.Onlywrittenappealswillbeconsidered.RejectedmanuscriptsmayberesubmittedforconsiderationonlywithexplicitpermissionoftheEditor-in-Chief.Insuchcases,thesubmissionwillbegivenanewmanuscriptnumberanddateofreceipt,andwillbetreatedasanewmanuscript.

MANUSCRIPTPUBLICATION(AFTERACCEPTANCE)

Coststoauthors

Submissioncharges:None($0)

Pagecharges:None($0)

Colorcharges:TheJournalofProsthodonticstypicallydoesnotchargeauthorsforprintingtheirarticlesincolor.PrintingimagesincolorisattheEditor-in-Chief’sdiscretion.IftheEditor-in-Chieffeelscolorisunnecessaryforaspecificimage,buttheauthorsstillwouldlikeforittobeprintedincolor,theymaydosoforan$800USperpagecolorcharge.

Openaccess:Seebelow($3000US)

Offprints:FreeaccesstothefinalPDFoffprintofyourarticlewillbeavailableviaAuthorServices.PleasesignupforAuthorServicesifyouwouldliketoaccessyourarticlePDFoffprintuponpublicationofyourpaper,andenjoythemanyotherbenefitstheserviceoffers.Visithttp://authorservices.wiley.com/bauthor/tosignupforAuthorServices.

Ifyouwishtoorderhardcopyoffprintsfromthisjournalpleasevisit:https://caesar.sheridan.com/reprints/redir.php?pub=10089&acro=JOPR

UpdatedMarch15,2019

Open access and copyright

Shouldyourarticlebeacceptedforpublication,WileyPublishingwillprovidethecorrespondingauthorwithcopyrightagreements,whichmaybesignedelectronically.

TheJournalofProsthodonticsoffersOnlineOpenpublicationforafee($3000US)thatwillbecollectedbyWileyPublishingatthetimecopyrightissigned.ByselectingtheOnlineOpenoptionyouhavethechoiceofthefollowingCreativeCommonsLicenseopenaccessagreements:

CreativeCommonsAttributionLicenseOAA

CreativeCommonsAttributionNon-CommercialLicenseOAA

CreativeCommonsAttributionNon-Commercial-NoDerivsLicenseOAA

Topreviewthetermsandconditionsoftheseopenaccessagreementspleasevisithttp://www.wileyopenaccess.com/details/content/12f25db4c87/Copyright--License.html.

Directdepositionofpublishedmanuscripttorepositories

Certainfunders,includingtheNIH,membersoftheResearchCouncilsUK(RCUK),andWellcomeTrustrequiredepositoftheAcceptedVersioninarepositoryafteranembargoperiod.Detailsoffundingarrangementsaresetoutatthefollowingwebsite:

http://www.wiley.com/go/funderstatement.Pleasecontactthejournalproductioneditorifyouhaveadditionalfundingrequirements.

Institutions:WileyhasarrangementswithcertainacademicinstitutionstopermitthedepositoftheAcceptedVersionintheinstitutionalrepositoryafteranembargoperiod.Detailsofsucharrangementsaresetoutatthefollowingwebsite:http://www.wiley.com/go/funderstatement.

Onlinepublicationandproofreading

TheJournalofProsthodonticspublishesmostcontentonlineaheadofprintfirstasan“AcceptedArticle.”AcceptedArticlesaremadeupofthefilessubmittedforreviewandapprovedforpublication.Theyarenotproofreadortypeset.AcceptedArticlesaretypicallyplacedonlinewithin7businessdaysofacceptance.

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Aftertypesetting,thedesignatedcorrespondingauthorwillbeprovidedwithproofsandisaskedtoproofreadthemfortypesettingerrors.Importantchangesinthedataareallowed,butauthorswillbechargedforexcessivealterationsinproof.

Afterthetypesettingandproofreadingprocessiscomplete,theAcceptedArticlewillbereplacedbythe“EarlyView”article.ThisistheversionofrecordandincludesafunctionalhtmlversionofthearticleandatypesetPDF.Thiswillbethefinalversionofthemanuscriptandwillsubsequentlyappear,unchanged,inprint.

OnlineproductiontrackingisavailableforyourarticlethroughWileyAuthorServices.AuthorServicesenablesauthorstotracktheirarticle–onceithasbeenaccepted–throughtheproductionprocesstopublicationonlineandinprint.Authorscancheckthestatusoftheirarticlesonlineandchoosetoreceiveautomatede-mailsatkeystagesofproduction.Theauthorwillreceiveane-mailwithauniquelinkthatenablesthemtoregisterandhavetheirarticleautomaticallyaddedtothesystem.Visithttp://authorservices.wiley.com/formoredetailsononlineproductiontrackingandforawealthofresourcesincludingFAQsandtipsonarticlepreparation,submission,andmore.

JOURNALOFPROSTHODONTICSETHICALPOLICIESDatasharingandbioethics

HumanandotheranimalexperimentsFororiginalresearchmanuscriptsreportingexperimentsonanimals,thecorrespondingauthormustconfirmthatallexperimentswereperformedinaccordancewithrelevantguidelinesandregulations.Themanuscriptmustincludeastatementidentifyingtheinstitutionaland/orlicensingcommitteeapprovingtheexperiments,includinganyrelevantdetailsregardinganimalwelfare,patientanonymity,drugsideeffects,andinformedconsent.

Forexperimentsinvolvinghumansubjects,authorsmustidentifythecommittee(e.g.,InstitutionalReviewBoard[IRB])approvingtheexperimentsandincludewiththeirsubmissionastatementconfirmingthatinformedconsentwasobtainedfromallsubjects.AllhumanstudiesmustadheretotheprinciplessetoutintheDeclarationofHelsinki(WorldMedicalAssociationDeclarationofHelsinki,publishedonlineOctober19,2013.doi:10.1001/jama.2013.281053).

Itistheauthor’sresponsibilitytoensurethatapatient’sanonymitybecarefullyprotectedandtoverifythatanyexperimentalinvestigationwithhumansubjectsreportedinthemanuscriptwasperformedwithinformedconsentandfollowingalltheguidelinesforexperimental

investigationwithhumansubjectsrequiredbytheinstitution(s)withwhichalltheauthorsareaffiliated.Allidentifyingdetails(patientnamesand/orinitialsandnameofspecifichospitalunit)shouldberemovedfromthetext,tables,and/orradiographsorotherfigures.Patientsshouldbeassignednumbersinstead.Identifyingdatashouldberemovedfromamanuscriptunlessimportantclinicallyorepidemiologically.Clinicallyandepidemiologicallysignificantdetailsinclude:race,sex,age,occupation,countryorregionoforigin,and/orsexualorientation.Notethatthesameinformationmustbegivenforeachpatientorgroup.Ifanyindividualdataisincluded,writtenconsentforparticipation/publicationmustbegivenforeachpatientorgroup.

Ifanyindividualdataisincluded(i.e.,anidentifiablefull-facepictureinaclinicalreport),writtenconsentforparticipation/publicationmustbeobtainedfromeveryindividualwhosedataisincluded.Awrittenstatementattestingthattheauthorhasreceivedandarchivedsuchwrittenpatientconsentmustaccompanythemanuscript.Forresearcharticles,ifauthorscannotobtainconsenttopublishindividualdatatheymayonlyprovidesummaryresults.Exclusionstothisinclude:

• Thepatientsarede-identified• Thepatientsaredead• TherehasbeenawaivergrantedbytheInstitutionalReviewBoard(IRB).

PermissionsForm:Ifidentifyingdetailsmustberetained,theauthormustattesttheyhaveinformedconsentfromthepatients(asignedpermissionsform),seeAppendixAbelow.PermissionsmustappearinEnglish.Inthecaseofanon-Englishspeakingpatient/authorthepermissionshouldappearfirstinthenativelanguagewiththetranslationtoEnglishbelowandthesignaturefollowingboth.Ifthepatientcannotbelocatedorrefusestoconsenttopublication,themanuscriptwillNOTbepublished.Intheeventthatthepatientcannotprovideconsentduetodeathorlegalincompetency(thisincludesphotosofcorpses)permissionfromthepowerofattorneyisneededaswellasproofofpowerofattorney.Ifthepatientisaminor,alegalguardianmustprovidepermission.PreviouspublicationofnewscoveragedoesNOTeliminateapatient’srighttoprivacyanddoesNOTnegatetheneedforpatientpermission.Thisinformedconsentshouldbeindicatedinthetextofthearticle(intheMethodssection,ifappropriate)orintheAcknowledgmentsattheendofthearticle.Permissionsformsshouldbeuploadedatthetimeofsubmission.Articleswillnotberevieweduntilpermissionsformsaresubmitted.

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Reporting guidelines

TheJournalofProsthodonticsencouragesauthorstoregisterclinicaltrialspriortosubmissionatoneoftheregistrationsiteslistedbelow.TheregistrationnumberanddateofregistrationshouldbeincludedintheMaterialsandMethodssection.Pleaseseehttp://www.clinicaltrials.gov/ct2/about-studies/learn#WhatIsformoreinformationregardingclinicaltrials.• U.S.NationalInstitutesofHealthClinicalTrialsRegistry-http://www.clinicaltrials.gov• EUClinicalTrialsRegister-https://www.clinicaltrialsregister.eu• WHOInternationalClinicalTrialsRegistryPlatform-http://www.who.int/ictrp/en

Conflictofinterest

Authorsarerequiredtodiscloseanypossibleconflictsofinterest.Theseinclude,forexample,patent,ownership,employment,stockownership,consultancies,speaker'sfee.Author'sconflictofinterest(orinformationspecifyingtheabsenceofconflictsofinterest)willbeincludedonthetitlepageofpublishedarticles.

Authorship

Requirementsforallcategoriesofarticleslargelyconformtothe“UniformRequirementsforManuscriptsSubmittedtoBiomedicalJournals,”developedbytheICMJE.Amanuscriptwillbeconsideredforpublicationwiththeunderstandingthat:

• allnamedauthorshaveagreedtoitssubmission• itisnotcurrentlybeingconsideredforpublicationbyanotherjournal• ifthepaperisaccepted,itwillnotsubsequentlybepublishedinthesameorsimilar

forminanylanguagewithouttheconsentofpublisher

Eachauthormusthavecontributedsufficientlytotheintellectualcontentofthesubmission.Anychangestotheauthorlistaftersubmission,suchasachangeintheorderoftheauthors,orthedeletionoradditionofauthors,willfollowtheguidelinesassetoutbyCOPE(http://publicationethics.org/).Thecorrespondingauthormustconfirmthatheorshehashadfullaccesstothedatainthestudyandfinalresponsibilityforthedecisiontosubmitforpublication.TheICMJErecommendsthatauthorshipbebasedonthefollowing4criteria:

1. Substantialcontributionstotheconceptionordesignorthework;ortheacquisition,analysis,orinterpretationofdataforthework;AND

2. Draftingtheworkorrevisingitcriticallyforimportantintellectualcontent;AND3. Finalapprovaloftheversiontobepublished;AND

4. Agreementtobeaccountableforallaspectsoftheworkinensuringthatquestionsrelatedtotheaccuracyorintegrityofanypartoftheworkareappropriatelyinvestigatedandresolved.

Inadditiontobeingaccountableforthepartsoftheworkheorshehasdone,anauthorshouldbeabletoidentifywhichco-authorsareresponsibleforspecificotherpartsofthework.Inaddition,authorsshouldhaveconfidenceintheintegrityofthecontributionsoftheirco-authors.

Whenalargemulti-authorgrouphasconductedthework,thegroupideallyshoulddecidewhowillbeanauthorbeforetheworkisstartedandconfirmwhoisanauthorbeforesubmittingthemanuscriptforpublication.Allmembersofthegroupnamedasauthorsshouldmeetallfourcriteriaforauthorship,includingapprovalofthefinalmanuscript,andtheyshouldbeabletotakepublicresponsibilityfortheworkandshouldhavefullconfidenceintheaccuracyandintegrityoftheworkofothergroupauthors.

Acquisitionoffunding,collectionofdata,orgeneralsupervisionoftheresearchgroupalonedoesnotconstituteauthorship.Allpersonsdesignatedasauthorsshouldqualifyforauthorship,andallthosewhoqualifyshouldbelisted.Eachauthorshouldhaveparticipatedsufficientlyintheworktotakepublicresponsibilityforappropriateportionsofthecontent.

ContributionsbyindividualswhomadedirectcontributionstotheworkbutdonotmeetalloftheabovecriteriashouldbenotedintheAcknowledgmentssectionofthemanuscript.Examplesinclude:astatisticianwhohasconsultedontheincludedstatisticaltests;acolleaguewhohaseditedthedocumentforEnglishclarity,butdidnotcontributetothecontent;aphotographerorartistwhopreparedthefigures;adentaltechnicianorassistantwhowasinvaluabletothecareofthepatientbeingreportedon.

Medicalwritersandindustryemployeescanbecontributors.Theirroles,affiliations,andpotentialconflictsofinterestshouldbeincludedintheauthorlistornotedintheAcknowledgmentswiththeircontributiontotheworksubmitted.Failuretoacknowledgethesecontributorscanbeconsideredinappropriate.

Plagiarism

SubmittedmanuscriptsarerandomlyevaluatedviatheiThenticateProfessionalPlagiarismPreventionprogram(www.ithenticate.com).

TheJournalofProsthodonticsdefinesmajorplagiarismasanycaseinvolving:

UpdatedMarch15,2019

• unattributedcopyingofanotherperson'sdata/findings,orresubmissionofanentirepublicationunderanotherauthor'sname(eitherintheoriginallanguageorintranslation),or

• verbatimcopyingof>100wordsoforiginalmaterialintheabsenceofanycitationtothesourcematerial,or

• unattributeduseoforiginal,published,academicwork,suchasthestructure,argumentorhypothesis/ideaofanotherpersonorgroupwherethisisamajorpartofthenewpublicationandthereisevidencethatitwasnotdevelopedindependently.

Minorplagiarismisdefinedas:

• verbatimcopyingof<100wordswithoutindicatingthattheseareadirectquotationfromanoriginalwork(whetherornotthesourceiscited),unlessthetextisacceptedaswidelyusedorstandardized(e.g.,thedescriptionofastandardtechnique)

• closecopying(notquiteverbatim,butchangedonlyslightlyfromtheoriginal)ofsignificantsections(e.g.,>100words)fromanotherwork(whetherornotthatworkiscited).

IftheeditorialboardoftheJournalofProsthodonticssuspectsacaseofplagiarism,wewillfirstcontacttheauthorsforclarification.Iftheauthorsareunabletosufficientlyexplainthepotentialplagiarism,wereservetherighttoinformtheauthors'institutionsandfundingagencies.Ifapublishedarticleissuspectedofplagiarism,wewilltakethefurtherstepofinformingourreaders,potentiallyviaretractionofthearticle.

Retractionpolicy

IntheunfortunateeventanarticlepublishedintheJournalofProsthodonticsneedstoberetracted,wewillfollowtheguidelinesoftheCommitteeonPublicationEthics(COPE) here: http://publicationethics.org/resources/guidelines-new/guidelines-retracting-articles.Potentialreasonsforretractionincludeplagiarism,redundantpublication,orunreliableresults(eitherthrougherrorormisconduct).

Correctionspolicy

Ifauthorsorreadersnoteanerrorinapublishedarticle,theymaycontacttheeditorialoffice.Ifthecorrectionisminor(i.e.,theinstitutionofanauthorshouldbechanged,ortherewasatypographicalerror),theJournalofProsthodonticswillpublishanerrornoticeattheEditor-in-Chief’sdiscretion.Iftheerrorismajor(i.e.,testswereincorrectlyconducted,previouslypublishedworkwasmis-interpreted),pleasesubmitalettertotheeditoroutliningthepotentialerrors.Sucherrorscouldpotentiallyleadtothearticlebeingretracted.

UpdatedMarch15,2019

Standard release form, v 2.0 (July 2013)

STANDARD RELEASE FORM

For use of photographs, audio files, video clips, biographical information, and quotations from interviews For patient consent use dedicated form

I, _____________________________________________________[NAME OF SUBJECT / PARENT / GUARDIAN] (the “Licensor”), give my permission to include any images, video clips, audio files, biographical information, and interview quotations from which I [OR NAME OF CHILD] ___________________________________may be identified (the “Material”). in _________________________________________________________________________________[TITLE OF WORK] (the “Work”) to be published by John Wiley & Sons, Inc. or one of its affiliated companies (“Wiley”). I grant Wiley the right to use this Material

• in the Work and and in any related derivative and ancillary Works published by Wiley or its licensees • for worldwide distribution • in print and/or electronic delivery platforms in any and all media now known or hereafter developed • in all editions, for the life of those editions without restriction • in all languages • in advertisements and promotional materials for the Work.

I represent and warrant that (i) I am the sole owner of all copyright, trademark, and other intellectual property and proprietary rights in and to the Material, (ii) Wiley's publication of the Material as authorized herein will not violate or infringe any copyright, trademark, or other intellectual property or proprietary right of any person or entity, and (iii) I am not a party to and the Material is not subject to any contract or arrangement which would conflict with my permission herein.

This Agreement shall be governed by, and construed in accordance with: 1) the laws of England and Wales, if the Licensor is located outside of the United States, or 2) the laws of the State of New York, if the Licensor is located in the United States. In relation to any legal action or proceedings to enforce this Agreement or arising out of or in connection with this Agreement each of the parties irrevocably submits to the non-exclusive jurisdiction of the courts: 1) in England and Wales, if the Licensor is located outside of the United States, or 2) in New York, New York, if the Licensor is located in the United States. Please indicate your agreement by signing and returning this form. In signing, you warrant you have no claim on ground of breach of confidence or on any ground in any legal system against _________________________________________________________________________________________[NAME OF AUTHORS] in respect of the publication of images of, or quotations from, you. *If the subject is under the age of 16, consent should be given by a parent or guardian and the relationship to the subject indicated.

____________________________________________________________________________________________ I/We hereby grant permission for the use of the material requested above. Name of Subject / Parent / Guardian: ............................................................................. Signature of Subject / Parent / Guardian: …………………………………………………………………. Address: ……………………………………………………………………………………………………………………… ……………………………………………………………………………………………………………………………………. Date:.........................................

UpdatedMarch15,2019

APPENDIXB:MANUSCRIPTSUBMISSIONCHECKLISTThissubmissionchecklistisprovidedtohelpauthorsinthefinalstageofsubmission.Followingthischecklistshouldensuretheeditorialofficedoesnotreturnyourmanuscripttoyoupriortoevaluation.AmorecompletedescriptionofeachitemisprovidedundertheappropriateheadingintheInformationforAuthorsdocument.Separatedocumentsaresubmittedinthefollowingorder:(1)coverletter;(2)titlepage,includinganypreviouspresentationandexplanationofanyconflictsofinterest;(3)maintextfile(manuscriptwithoutauthoridentifiersandwithouttrackchanges)includingastructuredorstandardabstract,keywords,bodyofthetext,tables,figurelegends;(4)figures;(5)supplementaryfiles(ifnecessary)TitlePage☐Title☐Runningheadofnomorethan60characterspaces☐Author(s)fullname(s)writtenasFirstNamethenLastName,andacademicdegree(s)☐Theinstitutionalaffiliation(s)oftheauthor(s)atthetimeofthestudy.Anasteriskafteranauthor’snameandafootnotemayindicateachangeinaffiliation.Department,Institution,Locations.(Example:DepartmentofProsthodontics,UniversityofNorthCarolinaSchoolofDentistry,ChapelHill,NC)☐Acknowledgmentofanypresentationofthismaterial,towhom,when,andwhere.☐Acknowledgmentoffinancialsupport,includinggrantnumbers☐Explanationofanyconflictsofinterest☐Name,address,ande-mailaddressofcorrespondingauthorManuscriptBody☐Nolinenumbers☐StatementisincludedinthebodyofthemanuscriptthathumanexperimentationhasbeenapprovedbythelocalinstitutionalreviewboardorconformstoHelsinkiDeclaration☐Guidelinesforthecare/useofanimals,approvedbytheinstitution,havebeenfollowedasindicatedintheMethods☐ItisrecommendedthataprofessionaleditororacolleaguefluentinEnglisheditthemanuscriptbeforesubmissionforauthorswhosefirstlanguageisnotEnglish☐ThebodyofresearchmanuscriptsincludestheIntroduction(noheadingneeded),Methods,Results,Discussion,andConclusionsheadings☐ThebodyofclinicalreportsandtechniquemanuscriptsincludestheIntroduction(noheadingneeded),ClinicalReport/Technique,Discussion,andSummaryheadings

UpdatedMarch15,2019

Abstract☐ForOriginalResearchArticles,andReviewArticles,astructuredabstractisincludedbeforethebodyofthemanuscriptfollowedbykeywords☐ Forothermanuscripts(e.g.,ClinicalReports/Techniquearticles),includeaconventional,unstructuredabstractfollowedbykeywords

Styleguide☐Abbreviations:spelloutthefirsttimeused.Example:Fixedpartialdentures(FPDs);canbe called“FPD”whenusedagain;donotuseabbreviationsintheabstract☐Equipmentand/ormaterialsareidentifiedintextbythemanufacturerandcityandstate(US manufacturer)orcityandcountry(non-USmanufacturer).Example:(WhipMix,Louisville,KY);(3Shape,Copenhagen,Denmark)☐Formattingofreportedvalues,statisticaltestsconformtoJournal of Prosthodonticsauthor guidelines

References☐Allreferencesarenumberedconsecutivelyintheordertheyarecitedinthetext☐ReferencesareArabicnumerals(i.e.,1,2,3,etc)insuperscript☐Referencesappearafterpunctuationmarks☐Alllistedreferenceshavebeencitedinthetext

Tables☐Tablesarecitedinnumericsequenceinthetext☐TablesshouldbesubmittedinWord

Figures☐EachisnumberedwithanArabicnumeralandcitedinnumericsequenceinthetext☐Photographsofrecognizablepersonsrequireasignedreleasefromthepatientorlegalguardianauthorizingpublication☐FiguresshouldbesubmittedinPDF,JPG,EPS,orTIFFformat☐Figureswithmultiplepanels(Figure1A,1B)shouldbesubmittedasasinglefile

Permissions☐Signed,writtenpermissionfromboththecopyrightholderandtheoriginalauthorfortheuseoftables,figures,orquotationspreviouslypublishedandtheircompletereferencesisonfilewiththeauthorandcanbesubmittedtotheeditorialofficeuponrequest☐Informedconsentandreleasestopublishphotographsofrecognizablepersonsshouldbeonfilewiththeauthorandsubmittedtotheeditorialofficeuponrequest

Revisions

UpdatedMarch15,2019

Inadditiontotheabove:☐Ahighlightedormarked-upcopyshouldbesubmittedshowingallofthechangesmadethroughoutthemanuscript;donotusetheWord“TrackChanges”feature☐Provideaseparatefileasaresponsetothereviewersandeditorsdetailingthechangesmadeorthechangesnotmade,andwhytheauthorchosenottomakethechanges.

UpdatedMarch15,2019

APPENDIXC:RESPONSETOREVIEWERSTEMPLATEUse this format to respond to reviewers and editors (the remarks in this template are anexampleonly).ResponsetoReviewer1:1)Themainfindings inthismanuscriptbearaclosesimilaritytootherpreviouslypublishedworkandIfeelthattheyaddlittletotheconclusionsofthatmanuscript.Response:Werespectthecommentofthereviewerandappreciatetheirinsight.However,wefeelthatthe previous paper being referred to does differ from our current submission and that the currentmanuscript adds new data that continues to build upon the programmatic theme of our laboratory.(Discussionofdifferencesinthetwoworkshasbeenredactedtoshortenthisdocument)TextChange:Wehaveexpandedourdiscussiontoreflectthesedifferences,seepage4.2)BSPIIandosteopontinarewellknowntobeproducedbyosteoblast-likecellsinculture.Response:Thisistrue.However,theresultshavebeennotedinstandard2Dcultures.Veryfewstudieshaveanalyzedtheexpressionoftheseproteinsin3Dculturesaswehavesubmitted.WehavepreviouslyreporteddifferencesinspatialandtemporalexpressionofBSPIIina3Dmandibularbovinemodel(Bone1999).Howeverwedidnotwanttoassumethatexpressioninthosemodelswouldalsotranslatetotheaggregatemodelwedescribehere.TextChange:None.3)ItisnotsurprisingthataggregateSizeCorrelatedtoStartingCellNumber,butperhaps"correlated"isthewrongwordastherewasnorigorousstatisticaltreatment.Response: Weappreciate thecommentandhavemodified the textaccordingly tostate thesizewasassociatedwithculturedcellnumber.TextChange:Abstract,Resultsheadingspage7and8.ResponsetoReviewer2:1)Typographicerrorswarrantauthor’sattention.Response:Thankyou.TextChange:Proofreadandcorrected.

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