size optimization of yag _ final

Alejandro Cota

http://www.mesotheliomaguide.com/wp-content/uploads/2014/05/PhotodynamicTherapy.png

Procedure:

• Intravenous insertion of

anticancer nano-drug

• Irradiate the tumor site

• Drug is released and the

tumor is targeted

Scintillator Ionizing

radiation Photo-

luminescence

Source: http://www.uspharmacist.com/content/s/197/c/33020/

• Larger than 10 nm

to avoid first-pass

elimination in the

kidney

• Smaller than 150 to

200 nm to avoid

clearance in the

liver and spleen

YAG:Pr

Alumina

Praseodymium

Yttrium

Methanol

Mix until solvent evaporates.

0

200

400

600

800

1000

1200

0 1 2 3 4 5 6 7

Tem

pera

ture

°C

Calcination Profiles

Time (hours)

~ 2 days

Filters

White: 450nm

Yellow: 450nm

Green: 220nm

Blue: 200nm

Filters

White: 450nm

Green: 220nm

Filters

Yellow: 450nm

Green: 220nm

Scale:100nm

Pictures taken by:

Dr. Novitskaya

Scale: 50nm

Pictures taken by:

Dr. Novitskaya

YAG:Pr

Aluminum

Praseodymium Yttrium

Carbohydrazide Fuel

Water

Combust at T = 500 °C

0

200

400

600

800

1000

1200

0 1 2 3 4 5 6 7

Tem

pera

ture

°C

Calcination Profiles

Time (hours)

~50 min

Sol-Gel Synthesis

Combustion Synthesis

Impurities

2ϴ

Pictures taken by: Dr. Novitskaya

Scale: 100nm

Pictures taken by: Ajay Sapre

Pictures taken by:

Dr. Novitskaya