mutations autosomal dominant
Post on 01-Jun-2015
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Mutations and Autosomal Dominant Heredity
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Mutations and Autosomal DominantDisorders
Genetic Mistakes
Mutations
Mutation – a change in the DNA message
Mutations cause the wrong protein to be made (they may no longer be functional)
3 Types of Mutations
Deletion – section of DNA removed
Insertion – section added
Substitution – bases switched
Causes of Mutations
Errors in replication or transcription
Powerful radiation: x-rays, UV light, etc.
Genetic Diseases
Can be caused by mutations or by additional/fewer chromosomes
CCMs are an autosomal dominant genetic disorder.
Autosomal Dominant Disorders
The mutated gene is dominant and presents in one parent.
The children have a 50% chance of being affected.
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