mapk pathway - docs.abcam.com · stimulus activators mapkkk mapkk mapk erk1 erk2 jnk1 jnk2 jnk3...
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Stimulus
Activators
MAPKKK
MAPKK
MAPK
ERK1 ERK2
JNK1 JNK2
JNK3 ERK5 BMK1p38 MAPK
Growth factors, Mitogens
Stress,Cytokines,
Growth factorsStress,
Growth factors,Mitogens
Raf Mos
Tpl2MEKK2 MEKK3
Tpl2
MLK3 TAK1
TAO1
DLK
MEKK3
ASK1
Tpl2
Ras
STE20 Rho TRAF2
TRAF3
Rac Rho
Src Rascdc42TRAF6
MEK1 MEK2 MEK5
MKK3 MKK4MKK4 MKK7
MKK6
TAO2 MEKK4
ZAK
MEKK1 MLK1/2/3/4 TAO2
MEKK2 ASK1 TAK1
MEKK4 TAO1
DLK ZAK
Fatty acid: albumin
EffectProliferationDifferentiation
InflammationApoptosisProliferationDifferentiationMetabolism
ProliferationDifferentiation
MAPK pathway
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