eecp: the natural bypass (enhanced external counterpulsation) · •vegf- increases 21% with 1 hour...

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EECP: The Natural Bypass (Enhanced External Counterpulsation)

Objectives

o Identify patient populations who should & should not have EECP.

o Summarize mechanism by which EECP tx is provided.

o Cite changes that occur to blood flow and blood vessels as a result of EECP tx.

o List EECP’s wide ranging benefits.

What is EECP?

• Treatment clinically proven to improve blood circulation and strengthen the CV system

• BP cuffs

• Promotes development of new blood vessels

• Reduction of s/s

Origin of EECP

o hydraulic device, water

o 1970’s

• Studies

• Focus on high tech, invasive approaches

o Renewed interest early ‘90’s

• FDA approved 1995

• Medicare 1999

Early external

counterpulsation

devices had

hydraulic pulsator

chambers.

Why Do We Need EECP?

o 10 million patients chronic angina

o 1/4-1/3 refractory angina

Who Should Have EECP?

o Coronary artery disease and angina

• CCS III and IV

Who Should Not Have EECP?

o Severe aortic insufficiency

o AAA >5 cm

o Hemophilia

o Uncontrolled hypertension >180/110 mmHg

o Pregnant, fever, open wound, current blood clot

Qualities of EECP Therapist

o Clinical assessment

o Wrap cuffs tightly

o Full Pressure (280 mmHg)

o Timing

o Coach

Safe

o NO risk of stroke, infection, cognitive impairment, bleeding.

No Recovery Time

o No convalescence- before work, lunch break.

Noninvasive

o No drugs, needles, IV, tubes, knives.

Painless

o Sleep, t.v. , music, chat

o “Bouncing appearance”

Saves $$

o Up front cost: $6000 full course EECP-

1/3 cost PCI, 1/6 cost CABG.

o Long term savings

o $215.6 billion lost annually

Good for the Soul

• Quality of life, emotional improvements

What Does EECP Do To Blood Flow?

o Diastolic augmentation- (sequential)

• Enhances venous blood flow

• Retrograde flow coronary circulation =

myocardial perfusion

o Systolic “unloading”- (simultaneous)

• Decreases heart’s demand for blood and oxygen

• Beat with increased force

Principles of Operation

Systolic Deflation Simultaneously deflate all three

sets of cuffs at the end of diastole

Effect:

Systolic Unloading

Reduce Cardiac

Workload

Increase

Cardiac

Output

Lower

Thigh

Cuffs

Upper

Thigh Cuffs

Calf Cuffs

Diastolic

Augmentation

Increase

Coronary Perfusion

Increase

Cardiac Output

Sequential inflate three

sets of cuffs at the end of

systole

Diastolic Inflation

ECG

Normal

EECP

Effects:

Increase

Venous Return

Lower

Thigh Cuffs

Upper Thigh

Cuffs

Calf Cuffs

Blood Vessels

o Organs- alive, dynamic, growing

o Exercise blood vessels- adequate blood transport

What Happens To Blood Vessels During EECP?

o Enhances vascular reactivity o Shear stress= anti-inflammatory properties o Endothelin (ET-1)- constricts, retains water & salt

• Decreases 40% during • 20% at one month post

o Nitric oxide- dilates and strengthens • Increases 60% during • 20% at one month post

o Endothelium release natural chemicals angiogenic growth factors • VEGF- increases 21% with 1 hour EECP

Natural Bypass

o Collaterals- “potential” blood vessels

o “wake up” or “recruite”

o Enlarge, strengthen, new lasting pathways

Heart Untreated Heart Treated with EECP

Benefits Of EECP!

o Increased: • Activity level • Blood flow • Quality of life • Energy • Cardiac output

o Decreased: • Anginal episodes 72-85% • Hospitalizations, ED visits 85% (in year following tx) • Nitroglycerin use 81% • Functional classification (CCS) by 1 class • Depression, anxiety

“Off Label” Uses of EECP

o PVD o Sleep o Erectile dysfunction o Athletes o Ocular o Renal o RLS o Tinnitus o Stroke o Alzheimer’s o Parkinson’s

Case Study

o 65 year old

o MI & CABG 1996

o Ischemic cardiomyopathy, EF= 25-30%

o ICD 2011

o TIA post PCI 2014

o Chronic angina

Jack

Jill.carter@hcmed.org

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