cheminform abstract: synthesis of new heterocyclic derivatives of retinoids
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1999 vitamins
vitaminsU 0900
18 - 220Synthesis of New Heterocyclic Derivatives of Retinoids. — Reactionof ionones (I) with Vilsmeier reagent affords enamines (IV) or the expectedchloro derivatives (III) depending on the work-up of the crude reaction mixture.Compound (IVa) reacts with hydrazines, guanidine, and hydroxylamine tofurnish pyrazoles (V), pyrimidine (VII), and isoxazole (VIII), respectively. —(SOTTOFATTORI, ENZO; ANZALDI, MARIA; BALBI, ALESSANDRO; J.Heterocycl. Chem. 35 (1998) 6, 1377-1380; Dip. Sci. Farm., I-16132 Genova,Italy; EN)
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