cheminform abstract: novel conformationally restricted tetracyclic analogues of...
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1999 benzopyran derivatives
benzopyran derivativesR 0350
46 - 146Novel Conformationally Restricted Tetracyclic Analogues of ∆8-Tetrahydrocannabinol. — The novel compounds are tested for theircannabinoid receptor binding activity. It is shown that the desired activitydepends on the orientation of the side chain and also on the distance to phenolring with (IX) being the most active compound. — (KHANOLKAR, AT-MARAM D.; LU, DAI; FAN, PUSHENG; TIAN, XIAOYU; MAKRIYANNIS,ALEXANDROS; Bioorg. Med. Chem. Lett. 9 (1999) 15, 2119-2124; Dep.Pharm. Sci., Sch. Pharm., Univ. Conn., Storrs, CT 06269, USA; EN)
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