anita macdonald. liquid protein substitute substitute

Anita MacDonaldAnita MacDonald

Liquid Liquid proteinprotein

substitutesubstitute

Liquid Liquid proteinprotein

substitutesubstitute

Liquid Liquid proteinprotein

substitutesubstitute

NaffNaff

ProblemsProblems

preparation timepreparation timeneed waterneed waterdirty containersdirty containers

too much efforttoo much effort

makes peoplemakes people look differentlook different

New liquid protein New liquid protein substitutesubstitute

Cooler130 ml pouches> 8 yearsaverage dose: 4

pouches daily

How goodHow good is liquid Cooler?is liquid Cooler?

do people prefer it?

does it affect blood phenylalanine control?

is it easier than powder?

are people embarrassed when taking it?

Who did we study?Who did we study?

26 people26 peopleaged: 8y – 49yaged: 8y – 49y14 female14 female12 male12 malemost took PKU most took PKU

Express powderExpress powder

What did we do?What did we do?

3 parts: 6 weeks3 parts: 6 weeks

compared liquid protein compared liquid protein substitute with substitute with powdered equivalentpowdered equivalent

Part 1/2Part 1/2 Part 1/2Part 1/2

2 weeks2 weeks 2 weeks2 weeks

Part 1/2Part 1/2 Part 1/2Part 1/2

Part 1/2Part 1/2 Part 1/2Part 1/2 Part 3Part 3

2 weeks2 weeks 2 weeks2 weeks2 weeks2 weeks

What did we study?What did we study?

preference wastage self

consciousness phenylalanine

levels

EvaluationEvaluation

0

20

40

60

80

100

120

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26

% of either product chosen in part 3

Subjects

%

Liquid

Powder

Ph

en

yla

lan

ine

(u

mo

l/l)

LiquidPowder

1400

1200

1000

800

600

400

200

0

p=0.027p=0.027

Blood phenylalanine controlBlood phenylalanine control

0

20

40

60

80

100

120

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26

Subjects

%

%

Wastage

0

20

40

60

80

100

120

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26

p=0.001p=0.001

0

10

20

30

40

50

60

70

80

90

100

%%

9292

3838

How easy was it to take?How easy was it to take?

liquidliquid powderpowder

p<0.001p<0.001

Feeling self consciousFeeling self conscious

0

5

10

15

20

25

30

35

40

45

50

%

liquid

powder

50

21 2125 25

No self consciousnessNo self consciousness on liquid but with powderon liquid but with powder

No self consciousnessNo self consciousness on eitheron either

Self conscious on bothSelf conscious on both

p=0.003p=0.003

LiquidLiquidmore convenient: more convenient: p=0.002p=0.002

easier to take outside the home: easier to take outside the home: p=0.001p=0.001

Friends don’t notice!

less bullying

at school

Don’t need to hide in toilet

friends

say

powder

is like sick

ConclusionsConclusions

Liquid CoolerLiquid Cooler

popular

easy

convenient

ConclusionsConclusions

Liquid CoolerLiquid Cooler

popular

easy

convenient

It It rocksrocks

!!!!

Cooking 4 FunCooking 4 Fun

lovedlovedfajitas fajitas

Helped me Helped me trytry

new thingsnew things

Other children Other children watch….and want to watch….and want to

make thingsmake things

Easy and simpleEasy and simple

……loves makingloves makingRainbow dropsRainbow drops