HypertensionPulmonary

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ALMA MATER STUDIORUMUNIVERSITÀ DI BOLOGNA

DIPARTIMENTO DI MEDICINA SPECIALISTICA,DIAGNOSTICA E SPERIMENTALE

An educational event of the University of Bologna

Master Degree in Pulmonary Vascular Diseases

BOLOGNA

June 16-17, 2017

Archiginnasio Palace

Faculty

Clemens AignerRuhrlandklinik - West German Lung CenterWest German Center for Lung TransplantationUniversity Hospital EssenEssen, Germany

Joan Albert Barberà Department of Pulmonary Medicine Hospital ClinicUniversity of Barcelona Barcelona, Spain

Rolf M.F. Berger Pediatric and Congenital Cardiology Center for Congenital Heart Diseases Beatrix Children’s HospitalUniversity Medical Center Groningen, The Netherlands

Damien Bonnet M3C Necker Enfants MaladiesAP-HP University Paris Descartes Paris, France

Guillermo R. BortmanTransplant, Heart failure and PH Unit Sanatorio de la Trinidad MitreBuenos Aires, Argentina

Shigefumi FukuiDepartment of Cardiovascular MedicineNational Cerebral and Cardiovascular CentreOsaka, Japan

Sean Patrick Gaine National Pulmonary Hypertension Unit Mater Misericordiae University Hospital Dublin, Ireland

Nazzareno Galiè Department of Experimental, Diagnostic and Specialty Medicine - DIMES Alma Mater Studiorum University of Bologna Bologna, Italy

Simon Gibbs Department of Cardiology Imperial College London and Hammersmith Hospital London, United Kingdom

Enrico Gotti Department of Experimental, Diagnostic and Specialty Medicine - DIMES Alma Mater Studiorum University of Bologna Bologna, Italy

Marc Humbert Department of Pneumology and ICU National Reference Center for Pulmonary Hypertension South Paris University Bicêtre Hospital, Le Kremlin Bicêtre, France

Alessandra Manes Department of Experimental, Diagnostic and Specialty Medicine - DIMES Alma Mater Studiorum University of Bologna Bologna, Italy

Eckhard Mayer Department of Thoracic Surgery Kerckhoff-Klinik Bad Nauheim, Germany

Massimiliano Palazzini Department of Experimental, Diagnostic and Specialty Medicine - DIMES Alma Mater Studiorum University of Bologna Bologna, Italy

Stephan Rosenkranz 3rd Clinic of Internal Medicine and Centre for Molecular Medicine Heart Centre of Cologne University Cologne, Germany

Gérald SimonneauDepartment of Pneumology and ICUNational Reference Center forPulmonary HypertensionSouth Paris UniversityBicêtre HospitalLe Kremlin Bicêtre, France

Olivier Sitbon Department of Pneumology and ICU National Reference Center for Pulmonary Hypertension South Paris University Bicêtre HospitalLe Kremlin Bicêtre, France

Jean-Luc Vachiéry Erasme University Hospital Department of Cardiology Brussels, Belgium

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HypertensionPulmonary

b y c l i n i c a l c a s e s 2 0 1 7

08:30 REGISTRATION

09:15 INTRODUCTION TO THE MEETING OBJECTIVES N. Galiè

09:30 INITIAL COMBINATION THERAPY Chairs: N. Galiè, G. Simonneau

Case # 1 Triple O. Sitbon Case # 2 Double M. Palazzini

11:00 Coffee Break

11:30 THE USE OF PROSTACYCLIN ANALOGUES AND RECEPTORS AGONISTS Chairs: S. Gibbs, O. Sitbon

Case # 1 Oral S. Rosenkranz Case # 2 Parenteral M. Humbert

13:00 Lunch

14:00 ADVANCED CASES AND TRANSPLANTATION Chairs: M. Humbert, J.L. Vachiéry

Case # 1 Sequential triple combination in advanced cases S.P. Gaine

Case # 2 Bridging the patients to lung transplantation C. Aigner

Friday, June 16

PRESENTATION AND EDUCATIONAL STRATEGY

The purpose of the meeting is to discuss interactive clinical cases and present scientific evidence on different topics of pulmonary vascular diseases.Each speaker will present a clinical case which includes multiple choice questions to facilitate the interaction with the audience by individual keypads and collective real-time results. At the end of the discussion the speaker will review briefly the scientific evidence of the key points raised by the clinical case presentation.

15:30 Coffee Break

16:00 CONGENITAL HEART DISEASE AND PULMONARY HYPERTENSION Chairs: G. Bortman, A. Manes

Case # 1 Operable or not operable? D. Bonnet Case # 2 Treat and Repair? R.M.F. Berger

17:30 SUMMARY OF THE DAY N. Galiè

18:00 END OF THE SESSION

08:30 INTRODUCTION AND PRESENTATION OF THE DAY OBJECTIVES N. Galiè

09:00 HOW TO TREAT PH IN LEFT HEART DISEASE AND LUNG DISEASE Chairs: J.A. Barberà, S.P. Gaine Case # 1 Left Heart Disease J.L. Vachiéry Case # 2 Lung Disease J.A. Barberà

10:30 Coffee Break

11:00 HYBRID TREATMENTS IN CHRONIC THROMBOEMBOLIC PULMONARY HYPERTENSION Chairs: S. Fukui, N. Galiè Case # 1 Drugs + BPA E. Gotti Case # 2 PEA + BPA E. Mayer

12:30 Closing remarks N. Galiè

13:00 Lunch

BOLOGNAJune 16-17, 2017

Archiginnasio Palace

Friday, June 16

Saturday, June 17

ITALIAN CME CREDITSItalian CME credits have beenrequested.Provider Italian CME Credits:I&C srl PROVIDER: 5387ID CME ITALIAN CREDITS: 5387-193514CME CREDITS N. 7I&C srl is responsible for the content, the quality and the ethical honesty of the CME activity.The meeting is accredited for physicians, disciplines: Internal Medicine, Cardiology, Diseases Respiratory System, Rheumatology, Cardio Surgery, Thoracic Surgery, Vascular Surgery, General Surgery, Anesthesia and Resuscitation, General Medicine, Allergology and Clinical Immunology, Sport Medicine.The physicians belonging to other disciplines will not get the credits.

The attendance to the meeting is partially on sponsor companies invitation.

METHODOLOGY Residential

COURSE OBJECTIVESClinical, Diagnostic, Therapy, Treatment Path

LEARNING TESTThe credits will be obtained by attending both days of the meeting (90% of attendance), by answering correctly to the 75% of the CME test questions and by filling the CME forms delivered at the meeting.

EUROPEAN CME CREDITS(EACCME)Event code: 15816‘PULMONARY HYPERTENSION BY CLINICAL CASES – 2017’ is accredited by the European Accreditation Council for Continuing Medical Education (EACCME) to provide the following CME activity for medical specialists. The EACCME is an institution of the European Union of Medical Specialists (UEMS), www.uems.net.

The ‘PULMONARY HYPERTENSION BY CLINICAL CASES – 2017’ is designated for a maximum of 9 hours of European external CME credits. Each medical specialist should claim only those hours of credit that he/she actually spent in the educational activity.Through an agreement between the European Union of Medical Specialists and the American Medical Association, physicians may convert EACCME credits to an equivalent number of AMA PRA Category 1 Credits™. Information on the process to convert EACCME credit to AMA credit can be found at www.ama-assn.org/go/internationalcme.Live educational activities, occurring outside of Canada, recognized by the UEMS-EACCME for ECMEC credits are deemed to be Accredited Group Learning Activities (Section 1) as defined by the Maintenance of Certification Program of The Royal College of Physicians and Surgeons of Canada.

EACCME creditsEach medical specialist should claim only those hours of credit that he/she actually spent in the educational activity. The EACCME credit system is based on 1 ECMEC per hour with a maximum of 3 ECMECs for half a day and 6 ECMECs for a full-day event.

European CME credits have been requested for the following disciplines: Internal Medicine, Cardiology, Diseases Respiratory System, Rheumatology, Cardio Surgery, Thoracic Surgery, Vascular Surgery, General Surgery, Anesthesia and Resuscitation, General Medicine, Allergology and Clinical Immunology, Sport Medicine.

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MEETING VENUEArchiginnasio PalaceStabat Mater HallPiazza Galvani 1 – BolognaArchiginnasio Palace is in Bologna downtown.We suggest to park your car in: Staveco Parking (Viale Panzacchi, 10) or Piazza VIII Agosto Parking (10 minutes from the congress venue, walking distance).From the Train Station: bus n. 30 and A

SCIENTIFIC SECRETARIATProf. Nazzareno GalièDirector of the CourseDr. Alessandra ManesDr. Massimiliano PalazziniCenter of Diagnosis and Therapy of Pulmonary Arterial HypertensionDepartment of Experimental, Diagnostic and Specialty Medicine – DIMESAlma Mater StudiorumUniversity of BolognaVia Massarenti, 9 - 40138 BolognaTel. +39 (0)51 6364008 Fax +39 (0)51 344859e-mail: nazzareno.galie@unibo.it

ORGANIZING SECRETARIAT I&C s.r.l. Via A. Costa 202/6 40134 Bologna (Italy)Tel: +39 (0)51 6144004 Fax: +39 (0)51 6142772stefania.parolari@iec-srl.it;giulia.delia@iec-srl.it

With the unrestricted grant of

BOLOGNA

June 16-17, 2017

Archiginnasio Palace