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Alabama Medications Christopher J. Colvin January 2010

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Page 1: Alabama Drugs PPt. - Alabama Department of Public Healthadph.org/ems/assets/AlabamaDrugsPPT.pdf · also be used for Beta or Calcium Channel Blocker OD. ... Antidepressant overdose

Alabama Medications 

Christopher J. ColvinpJanuary 2010

Page 2: Alabama Drugs PPt. - Alabama Department of Public Healthadph.org/ems/assets/AlabamaDrugsPPT.pdf · also be used for Beta or Calcium Channel Blocker OD. ... Antidepressant overdose

Activated CharcoalActivated Charcoal

• Used to absorb toxins ingestedUsed to absorb toxins ingested before they can be absorbed in the GI system.

• Contraindicated in AMS patients who cannot control their airway

• On‐line medical direction must be contacted (Category B)

• Adult Dose: 1 g/kg• Side effects: Nausea and Vomiting.Side effects: Nausea and Vomiting. 

Page 3: Alabama Drugs PPt. - Alabama Department of Public Healthadph.org/ems/assets/AlabamaDrugsPPT.pdf · also be used for Beta or Calcium Channel Blocker OD. ... Antidepressant overdose

AdenosineAdenosine

• Slows conduction through the AV S o s co duct o t oug t eNode.

• Used to treat PSVT with or without WPW.

• Contraindications: 2nd or 3rd degree HB, Hypersensitivity, Pregnancy, Coronary Vasodilator, Tegratol.Ad lt D 6 12 12 RIVP• Adult Dose: 6mg, 12mg, 12mg, RIVP. Follow each administration with 20cc flush (CAT B)flush. (CAT B)

Page 4: Alabama Drugs PPt. - Alabama Department of Public Healthadph.org/ems/assets/AlabamaDrugsPPT.pdf · also be used for Beta or Calcium Channel Blocker OD. ... Antidepressant overdose

AlbuterolAlbuterol• Potent bronchodilator used to treat bronchial asthma andtreat bronchial asthma and reversible bronchial spasm.

• Contraindicated in symptomatic y ptachycardia. Watch for significant arrhythmia changes.St t t t if l i• Stop treatment if pulse increases 20bpm, PVC’s develop, or tachyarrhythmias other than y ysinus develop.

• Adult Dose: 2.5mg nebulized. (Cat A)(Cat A)

Page 5: Alabama Drugs PPt. - Alabama Department of Public Healthadph.org/ems/assets/AlabamaDrugsPPT.pdf · also be used for Beta or Calcium Channel Blocker OD. ... Antidepressant overdose

AmiodaroneAmiodarone

• Used in the treatment of life Used t e t eat e t o ethreatening arrhythmias such as v‐fib, pulseless VT. May also be used in h f f ’the treatment of frequent PVC’s under Medical control guidance as a dripdrip.

• May cause bradycardia• Adult dose: 300mg diluted in 30cc• Adult dose: 300mg diluted in 30cc ns, RIVP, followed by two more administrations at 150 mg.g

Page 6: Alabama Drugs PPt. - Alabama Department of Public Healthadph.org/ems/assets/AlabamaDrugsPPT.pdf · also be used for Beta or Calcium Channel Blocker OD. ... Antidepressant overdose

AsprinAsprin

• Inhibits Prostoglandin (ClottingInhibits Prostoglandin (Clotting Factors), used in the treatment of Unstable Angina, AMI’s, and Ischemic Chest Pain.

• Contraindicated in known allergy, GI bleeding, or if pt. has already taken 325mg in 24 hrs.

• Adult Dose: 4 – 81 mg chewable tablets (Cat A)

Page 7: Alabama Drugs PPt. - Alabama Department of Public Healthadph.org/ems/assets/AlabamaDrugsPPT.pdf · also be used for Beta or Calcium Channel Blocker OD. ... Antidepressant overdose

AtropineAtropine

• Primary indication is ysymptomatic bradycardia or asystole. May also be used in the treatment ofthe treatment of Organophosphate or nerve gas poisoning.

• Contraindicated in A‐Fib/Flutter or heart transplant patients.

• Adult Dose: 1mg IV/IO q 3 5• Adult Dose: 1mg IV/IO q 3‐5 min up to 0.04 mg/kg. May also given through ET. (CAT A)

Page 8: Alabama Drugs PPt. - Alabama Department of Public Healthadph.org/ems/assets/AlabamaDrugsPPT.pdf · also be used for Beta or Calcium Channel Blocker OD. ... Antidepressant overdose

Calcium GluconateCalcium Gluconate

• Used for the treatment of hyperkalemic asystole (Typically dialysis pt.) and calcium channel blocker overdoseblocker overdose.

• Contraindicated if possible Digitalis overdose, contact Medical Control to confirm drug taken is calcium channel blocker.

• Adult Dose: 1 2g IVP over two• Adult Dose: 1‐2g IVP over two minutes. (CAT A for Asystole, CAT B for CCB Overdose.)

Page 9: Alabama Drugs PPt. - Alabama Department of Public Healthadph.org/ems/assets/AlabamaDrugsPPT.pdf · also be used for Beta or Calcium Channel Blocker OD. ... Antidepressant overdose

50% Dextrose (D‐50)50% Dextrose (D 50)

• Used for the treatment of blood sugar gless than 70mg/dl or AMS patient where glucometer malfunctions.P ti D 50 ill ti• Precaution: D‐50 will cause tissue necrosis if IV extravasates. Thiamine should precede administration if psuspected alcohol abuse or malnutrition.

• Adult Dose One 50ml amp or 1ml/kg if• Adult Dose: One 50ml amp or 1ml/kg if pt is less than 50kg. (CAT A) 

Page 10: Alabama Drugs PPt. - Alabama Department of Public Healthadph.org/ems/assets/AlabamaDrugsPPT.pdf · also be used for Beta or Calcium Channel Blocker OD. ... Antidepressant overdose

DiazepamDiazepam

• Indicated for the treatment ofIndicated for the treatment of seizures or as a an analgesic prior to cardioversionprior to cardioversion.

• Contraindicated in alcohol use and CNS depression may causeand CNS depression, may cause respiratory depression.

Ad l D 5 10 SIVP (CAT A• Adult Dose: 5‐10 mg SIVP. (CAT A except Cardioversion.)

Page 11: Alabama Drugs PPt. - Alabama Department of Public Healthadph.org/ems/assets/AlabamaDrugsPPT.pdf · also be used for Beta or Calcium Channel Blocker OD. ... Antidepressant overdose

Diphenhydramine (Benadryl)Diphenhydramine (Benadryl)

• Used in the treatment ofUsed in the treatment of Anaphylaxis after the administration of IM Epinephrine.

• Contraindicated if known allergyContraindicated if known allergy exists or for nursing mothers. May cause hypotension.y yp

• Adult Dose: 25‐50mg deep IM or SIVP. (CAT A)( )

Page 12: Alabama Drugs PPt. - Alabama Department of Public Healthadph.org/ems/assets/AlabamaDrugsPPT.pdf · also be used for Beta or Calcium Channel Blocker OD. ... Antidepressant overdose

DopamineDopamine

• Used primarily to treat Used p a y to t eathypotension secondary to cardiogenic shock.

• Contraindicated in hypovolemic shock. Will be i ti t d if i th hinactivated if given through the same IV as Sodium Bicarbonate.Bicarbonate.

• Adult Dose: 2‐40mcg/kg/min (CAT B)( )

Page 13: Alabama Drugs PPt. - Alabama Department of Public Healthadph.org/ems/assets/AlabamaDrugsPPT.pdf · also be used for Beta or Calcium Channel Blocker OD. ... Antidepressant overdose

EpinephrineEpinephrine

• Indicated for all cardiac arrest arrhythmias, anaphylaxis, and asthma in patients under 40.

• Precautions include angina after• Precautions include angina after administration and tachycardia.

• Adult Dose: Cardiac Arrest 1mg ofAdult Dose: Cardiac Arrest 1mg of 1:10,000 q 3‐5 IV or IO, Anaphylaxis 0.3mg IM or SQ of 1:1 000 (CAT A) Adult acute1:1,000. (CAT A) Adult acute asthma 0.3‐0.5 mg 1:1,000 SQ (CAT B)

Page 14: Alabama Drugs PPt. - Alabama Department of Public Healthadph.org/ems/assets/AlabamaDrugsPPT.pdf · also be used for Beta or Calcium Channel Blocker OD. ... Antidepressant overdose

FurosemideFurosemide

• A potent diuretic used to treatA potent diuretic used to treat acute pulmonary edema.

• Contraindicated in• Contraindicated in hypovolemia or hypotension.

Ad l D 20 40 SIVP• Adult Dose: 20‐40mg SIVP over 2 min. (CAT B)

Page 15: Alabama Drugs PPt. - Alabama Department of Public Healthadph.org/ems/assets/AlabamaDrugsPPT.pdf · also be used for Beta or Calcium Channel Blocker OD. ... Antidepressant overdose

GlucagonGlucagon

• Primary indication isPrimary indication is hypoglycemic states where an IV cannot be established. May also be used for Beta or Calcium Channel Blocker OD.

• Precautions include tachycardia and N and V.

• Adult Dose: 1 mg IM, may be repeated once.

Page 16: Alabama Drugs PPt. - Alabama Department of Public Healthadph.org/ems/assets/AlabamaDrugsPPT.pdf · also be used for Beta or Calcium Channel Blocker OD. ... Antidepressant overdose

Hydroxocobalamin (Cyanide Kit)Hydroxocobalamin (Cyanide Kit)

• Indicated for known cyanide d cated o o cya depoisoning or smoke inhalation victims.

• Precautions include allergic reactions.

• Adult Dose: Draw one red top tube before administration. Mix 5g of HydroxocobalaminMix 5g of Hydroxocobalamininto 100cc of NS, give as an infusion over 15 min.

Page 17: Alabama Drugs PPt. - Alabama Department of Public Healthadph.org/ems/assets/AlabamaDrugsPPT.pdf · also be used for Beta or Calcium Channel Blocker OD. ... Antidepressant overdose

LidocaineLidocaine

• Indicated for the treatment of PVC’s, d cated o t e t eat e t o C s,V‐Tach with a pulse, or recurrent V‐Fib/V‐Tach following defibrillation d hand Epinephrine.

• Contraindicated in HR less than 60 or AV bl kAV blocks.

• Adult Dose: Bolus 1.5mg/kg initial followed by 0 75mg/kg for a total offollowed by 0.75mg/kg for a total of 4mg/kg max. 2‐4mg/min infusion to follow conversion.

Page 18: Alabama Drugs PPt. - Alabama Department of Public Healthadph.org/ems/assets/AlabamaDrugsPPT.pdf · also be used for Beta or Calcium Channel Blocker OD. ... Antidepressant overdose

LorazepamLorazepam

• Primary indication for statusPrimary indication for status seizures (SZ longer than 5 min continuously) May also becontinuously). May also be used before cardioversion.

• Do Not Mix with other agents• Do Not Mix with other agents.

• Adult Dose: 1‐2mg SIVP over 2 i (CAT A l hmin. (CAT A unless more than 

2mg is needed.)

Page 19: Alabama Drugs PPt. - Alabama Department of Public Healthadph.org/ems/assets/AlabamaDrugsPPT.pdf · also be used for Beta or Calcium Channel Blocker OD. ... Antidepressant overdose

Magnesium SulfateMagnesium Sulfate

• Indicated in the treatmentIndicated in the treatment of Eclampsia and Polymorphic V‐Tach.

• Precautions: Can lead to hypotension or respiratory arrest.

• Adult Dose: Mix 4g in 250cc bag of NS and infuse over 20 min.

Page 20: Alabama Drugs PPt. - Alabama Department of Public Healthadph.org/ems/assets/AlabamaDrugsPPT.pdf · also be used for Beta or Calcium Channel Blocker OD. ... Antidepressant overdose

Morphine SulfateMorphine Sulfate

• Narcotic analgesic indicated for any severe painNarcotic analgesic indicated for any severe pain or as an adjunct therapy for CHF or Pulmonary Edema.

• Contraindications: known allergy, blood pressure less than 90, or significant respiratory depression.less than 90, or significant respiratory depression. May cause N and V.

• Adult Dose: 4mg IVP initial followed by 2mg untilAdult Dose: 4mg IVP initial followed by 2mg until pain is managed every 3‐5 min to 10 mg max. (CAT A) 2‐4mg IVP for Pulmonary Edema. (CAT B)( ) g y ( )

Page 21: Alabama Drugs PPt. - Alabama Department of Public Healthadph.org/ems/assets/AlabamaDrugsPPT.pdf · also be used for Beta or Calcium Channel Blocker OD. ... Antidepressant overdose

Naloxone (Narcan)Naloxone (Narcan)

• Indicated for the reversal ofIndicated for the reversal of narcotic effects (morphine, codeine, etc).

• Precautions: Pt. is physically dependent on narcotic, Narcanmay cause immediate withdrawal symptoms.

• Adult Dose: 2mg given slowly IV, IM, SQ, or 4mg ET. (CAT A)

Page 22: Alabama Drugs PPt. - Alabama Department of Public Healthadph.org/ems/assets/AlabamaDrugsPPT.pdf · also be used for Beta or Calcium Channel Blocker OD. ... Antidepressant overdose

NitroglycerinNitroglycerin

• Indicated for angina, HTN, g , ,or pulmonary edema.

• Contraindicated in children May causechildren. May cause generalized vasodilationcausing profound BP drop, these effects can be magnified in pt.s taking medication for erectilemedication for erectile disfunction.

• Adult Dose: 0.4mg SL by bl (tablet or spray. (CAT A, 

CAT B for HTN)

Page 23: Alabama Drugs PPt. - Alabama Department of Public Healthadph.org/ems/assets/AlabamaDrugsPPT.pdf · also be used for Beta or Calcium Channel Blocker OD. ... Antidepressant overdose

Nitrous OxideNitrous Oxide

• Indicated for use in generalized pain management.

• Contraindicated in AMS• Contraindicated in AMS, intoxication, head injury, suspected pneumothorax, abdominal pain or distention, COPD.

• Adult Dose: Self• Adult Dose: Self‐administered until pain is relieved.  (CAT B)

Page 24: Alabama Drugs PPt. - Alabama Department of Public Healthadph.org/ems/assets/AlabamaDrugsPPT.pdf · also be used for Beta or Calcium Channel Blocker OD. ... Antidepressant overdose

Ondansetron (Zofran)Ondansetron (Zofran)

• Indicated for Nausea andIndicated for Nausea and Vomiting.

• Contraindications: Known• Contraindications: Known allergy, age less than one monthmonth.

• Adult Dose: 4mg IV or IM. (CAT A)(CAT A)

Page 25: Alabama Drugs PPt. - Alabama Department of Public Healthadph.org/ems/assets/AlabamaDrugsPPT.pdf · also be used for Beta or Calcium Channel Blocker OD. ... Antidepressant overdose

Sodium BicarbonateSodium Bicarbonate

• Used to control arrhythmias ysecondary to TricyclicAntidepressant overdose and acidosis secondary to cardiacacidosis secondary to cardiac arrest.

• Precautions: Too much may result yin alkalosis. May cause cerebral acidosis, particularly pt.s in DKA.

• Adult Dose 1mEq/kg followed by• Adult Dose: 1mEq/kg, followed by 0.5mEq/kg until pulse is restored. (CAT A for cardiac arrest, CAT B for TA overdose.)

Page 26: Alabama Drugs PPt. - Alabama Department of Public Healthadph.org/ems/assets/AlabamaDrugsPPT.pdf · also be used for Beta or Calcium Channel Blocker OD. ... Antidepressant overdose

ThiamineThiamine

• Indicated for malnutritionIndicated for malnutrition or alcoholism in the patient with low bloodpatient with low blood sugar. Administration should precede glucagonshould precede glucagon or D‐50.

• Adult Dose: 100mg IV or• Adult Dose: 100mg IV or IM. (CAT A)

Page 27: Alabama Drugs PPt. - Alabama Department of Public Healthadph.org/ems/assets/AlabamaDrugsPPT.pdf · also be used for Beta or Calcium Channel Blocker OD. ... Antidepressant overdose

VasopressinVasopressin

• Indicated for shock‐Indicated for shockrefractory VF, VT, PEA, or Asystole.

• Contraindications: Children, conscious pt.s.

• Adult Dose: 40 Units IVP, one time dose. (CAT A)