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Department of Chemistry

University of Delhi

Delhi

Ashok K Prasad

ashokenzyme@gmail.com

Professor Prasad obtained his PhD degree from University of Delhi in 1990.

He has carried out Postdoctoral Studies at the University of Southern Denmark, Odense & University of Copenhagen, Denmark; Max-Planck-Institute for Molecular

Physiology, Dortmund, Germany and at UMASS, Lowell, USA

His major research interest lies in the areas of

i) Biocatalysis and Biotransformations ii) Polymeric Architecture & Supra-molecular Chemistry

iii) Synthesis of Modified Nucleosides and Bioactive Heterocycles

He has been recipient of

i) Visiting Professor, JAIST, Japan- 2015 – 2017. ii) Visiting Associate Professor, SDU Denmark- 2008 - 2009.

iii) Excellence in Carbohydrate Research by ACCT (India)- 2015

iv) ISCB Award for excellence in Chemical Sciences- 2014 v) Best Paper Award from Trends in Carbohydrate Research- 2012

vi) CRSI Young Scientist Award 2007 vii) DANIDA Fellow (1992-96)

viii) National Meritorious Scholarship holder

Has been Editor / Guest editor of Journals, such as Biochemie; Indian J. Chemistry and Trends in Carbohydrate Research, etc

PUBLICATIONS: 217 Research Papers and 7 International and Indian Patents

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PUBLICATIONS

1. Synthesis of macromolecular systems via lipase catalyzed biocatalytic reactions: applications and future

perspectives.

A Kumar, A Khan, S Malhotra, R Mosurkal, A Dhawan, MK Pandey, BK Singh, AK Prasad, SK Sharma, LA

Samuelson, AK Cholli, C Len, NGJ Richards, J Kumar, R Haag, AC Watterson and VS Parmar

Chem. Soc. Rev., 2016 (Ahead of Print)

2. Chemo-enzymatic synthesis of 3'-O,4'-C-methylene-linked α-L-arabinonucleosides

R Kumar, M Kumar, J Maity and AK Prasad

RSC Advances, 2016, 6, 82432-82438.

3. Coumarin Derivatives as Adjuvants: From In Silico Physicochemical Characterization to In vitro Evaluation

against Gram Positive Bacteria

N Poughat, AK Chillar, AK Prasad, NN Senapati, S Khatri, M Kumar, S Srivastava, R Dabur

Comb. Chem. High Throughput Screen, 2016, 19, 489-496.

4. Hyperbranched glycerol-based core-amphiphilic branched shell nanotransporters for dermal drug delivery

S Stefani, S Hoenzke, JL Cuellar Camacho, L Jose, F Neumann, AK Prasad, S Hedtrich, R Haag and P Servin

Polymer, 2016, 96, 156-166.

5. Synthesis and anti-inflammatory activity evaluation of novel triazolyl-isatin hybrids

PK Sharma, S Balwani, D Mathur, S Malhotra, BK Singh, AK Prasad, C Len, EV Van der Eycken, B Ghosh,

NGJ Richards and VS Parmar

J. Enzyme Inhib. Med. Chem. 2016, 31, 1520-1526.

6. Mitigation of radiation-induced hematopoietic injury by the polyphenolic acetate 7, 8-diacetoxy-4-

methylthiocoumarin in mice

K Venkateswaran, A Shrivastava, PK Agrawal, AK Prasad, N Kalra, PR Pandey, K Manda, HG Raj, VS

Parmar and BS Dwarakanath.

Science Reports, 2016, 6, 37305.

7. Sugar-based novel chiral macrocycles for inclusion applications and chiral recognition.

A Singh, V Khatri, S Malhotra and AK Prasad

Carbohydrate Res. 2016, 421, 25-32.

8. Structure-activity relationship studies of 4-methylcoumarin derivatives as anticancer agents.

R Miri, M Nejati, L Saso, F Khakdan, B Parshad, D Mathur, VS Parmar, ME Bracke, AK Prasad, SK Sharma.

Pharmaceutical Biology, 2016, 54, 105-110.

9. Synthesis of 3'-azido/-amino-xylobicyclonucleosides.

M. Kumar, R Kumar, N Rana, AK Prasad

RSC advances 2016, 6, 17713-17719.

10. Synthesis of β-C-Glycopyranosyl Aldehydes and 2,6-Anhydro-heptitols.

V Khatri, A Kumar, B Singh, S Malhotra and AK Prasad

J. Org. Chem. 2015, 80, 11169–11174.

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11. A general, mild and efficient palladium-catalyzed 2,2,2-trifluoroethoxylation of activated aryl bromides and

bromo-chalcones: bromo-chalcones a new coupling partner in cross-coupling reaction.

T. Rangarajan, K. Devi, Ayushee, AK Prasad and RP Singh

Tetrahedron 2015, 71, 8307-8314.

12. Gapmer Oligonucleotides: Sugar-modified Wings to Antisense Therapeutics.

P Rungta, P Mangla, VK Sharma, SK Singh, A Chauhan, DT Masram, NN Senapati and AK Prasad

Trends Carbo. Res. 2015, 7, 28-43.

13. Biocatalytic route to C-3′-azido/-hydroxy-C-4′-spiro-oxetanoribo-nucleosides.

M. Kumar, VK Sharma, R. Kumar and AK Prasad

Carbohydrate Research 2015, 417, 19-26.

14. Cu(I)-Catalyzed Efficient Synthesis of 2'-Triazolo-nucleoside Conjugates.

D Mathur, N Rana, CE Olsen, VS Parmar and AK Prasad

J. Het. Chem 2015, 52, 701-710.

15. Design and Synthesis of Triazole-Linked xylo-Nucleoside Dimers.

S Srivastava, SK Singh, VK Sharma, P Mangala and AK Prasad

Nucleosides, Nucleotides and Nucleic Acids 2015, 34, 388-399.

16. Synthesis of potential bioactive novel 7-[2-hydroxy-3-(1,2,3-triazol-1-yl)propyloxy]-3-alkyl-4-

methylcoumarins.

A Arya, V Kumar, D Mathur, S Singh, R Brahma, RP Singh, S Singh, GL Sharma, VS Parmar and AK Prasad

J. Het. Chem. 2015, 52, 1-14.

17. Facile Access to 5'-S-(4,4'-Dimethoxytrityl)-2',5'-Dideoxyribo-nucleosides via Stable Disulfide Intermediates.

CSL Reddy, VK Sharma, R. Kumar, A. singh, VS Parmar and AK Prasad

Current protocols in Nucleic Acid Chemistry, 2015, 62, 1-9.

18. Nucleic Acid Based Therapeutics: Harnessing the Specificity.

VK Sharma, P Mangla, P Rungta and AK Prasad

Research Journal of Contemporary Concerns. 2015, 9, 3-8.

19. An Astute Synthesis of Locked Nucleic Acid Monomers.

VK Sharma, P Rungta, V Maikhuri and AK Prasad

Sustainable Chemical Processes 2015, 3, 1-6.

20. Mild and efficient palladium/BrettPhos-catalyzed methoxylation and deuteriomethoxylation of activated aryl

bromides.

TM Rangarajan, R. Brahma, Ayushee, AK Prasad, AK Verma and RP Singh

Tetrahedron Letters, 2015, 56, 2234-2237.

21. Highly Selective Biocatalytic Transesterification Reactions on Aryl 3-hydroxy-2-(hydroxymethyl)-2-

methylpropanoates.

G. Kumar, A. Dhawan, BK Singh, NK Sharma, SK Sharma, AK Prasad, EV Eyken, C. Len, AC Watterson and

VS Parmar

Catalysis Letters, 2015, 145, 919-929.

22. Self-assembly, photoresponsive behavior and transport potential of azobenzene grafted dendronized

polymeric amphiphiles.

M. Kumari, M. Billamboz, E. Leonard, C. Len, C. Bottcher, AK Prasad, R. Haag, SK Sharma

RSC Advances 2015, 5, 48301-48310.

23. Inhibition of Alzheimer’s BACE-1 by 2,6-Dialkyl-4-chromon-3-yl-1,4-dihydropyridin-3,5-dicarboxylates.

N Razzaghi-Asl, N Aggarwal, S Srivastava, VS Parmar, AK Prasad, R Miri, L Saso, O Firuzi

Med. Chem. Res. 2015, 24, 3230-3241.

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24. Anti-Inflammatory and Antioxidant Properties of Piper Species: A Perspective from Screening to Molecular

Mechanisms.

S Kumar, S Malhotra, AK Prasad, EV Van der Eycken, ME Bracke, WG Stetler-Stevenson, VS Parmar and B

Ghosh.

Current Topics in Medicinal Chemistry, 2015, 15, 886-893.

25. The Competence of 7,8-Diacetoxy-4-Methylcoumarin and Other Polyphenolic Acetates in Mitigating the

Oxidative Stress and their Role in Angiogenesis.

R Joshi, S Arora, A Kumar, S Manral, V Rohil, S Goel, N Priya, P Singh, P Ponnan, S Chatterji, BS

Dwarakanath, D Saluja, DS Rawat, AK Prasad, L Saso, E Kohli, AL DePass, ME Bracke, VS Parmar and HG

Raj

Current topics in medicinal chemistry, 2015, 15, 179-86.

26. BrettPhos ligand supported palladium-catalyzed C-O bond formation through an electronic pathway of

reductive elimination: Fluoroalkoxylation of activated aryl halides.

TM Rangarajan, R Singh, R Brahma, K Devi, RP Singh and AK Prasad

Chem. A Eur. J. 2014, 20, 14218-14225.

27. Chemo-enzymatic synthesis of C-4'-spiro-oxetanoribonucleosides.

VK Sharma, M Kumar, D Sharma, CE Olsen and AK Prasad

J. Org. Chem. 2014, 79, 8516-8521.

28. Chemo-enzymatic convergent synthesis of 2'-O,4'-C-methyleneribonucleosides.

VK Sharma, M Kumar, CE Olsen and AK Prasad

J. Org. Chem. 2014, 79, 6336-6341.

29. Synthesis of triazole linked LNA-based nonionic nucleoside dimers using click reaction.

SK Singh, VK Sharma, Kapil Bohra, CE Olsen and AK Prasad

Curr. Org. Chem. 2014, 11, 757-766.

30. Chemo-enzymatic synthesis of bicyclic 3′-azido- and 3′-amino-nucleosides.

M Kumar, VK Sharma, CE Olsen and AK Prasad

RSC Advances 2014, 4, 37231-37235.

31. Nucleic acid therapeutics: Basic concepts and recent developments.

VK Sharma, P Rungta and AK Prasad

RSC Advances 2014, 4, 16618-16631.

32. Effect of acyl chain length on selective biocatalytic deacylation on O-aryl glycosides and separation of anomers.

N Aggarwal, A Arya, D Mathur, S Singh, A Tyagi, R Kumar, N Rana, R Singh and AK Prasad

Bioorg. Chem. 2014, 53, 83-91.

33. Modifications of Cell Signalling and Redox Balance by Targeting Protein Acetylation Using Natural and

Engineered Molecules: Implications in Cancer Therapy.

K Venkateswaran, A Verma, AN Bhatt, PK Agrawala, HG Raj, S Malhotra, AK Prasad, O De Wever, MC

Bracke, L Saso, et al.

Current Topics in Medicinal Chemistry 2014, 14, 2495-2507.

34. Synthesis of sugar-modified triazole-linked nucleoside dimers.

K Bohra, S Srivastava, CE Olsen and AK Prasad

Trends in Carbo. Res. 2014, 6, 27-32.

35. Synthesis of 3'-azido-3'-deoxy-2'-O,4'-C-methylenenucleosides.

VK Sharma, M Kumar, V Maikhuri, A Tyagi and AK Prasad

Trends in Carbo. Res. 2014, 6, 1-6.

36. Novel approach to 3,3-dimethyl-4-morpholino-3,4-dihydrocoumarins via hetero-Diels-Alder reaction.

D Mathur, AK Prasad, ST Cameron and A Jha

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Tetrahedron 2014, 70, 5608-5618.

37. Comparison of protein acetyltransferase action of CRTAase with the prototypes of HAT.

P Ponnan, Prija, A Kumar, Ajit; P Singh, P Gupta, Prachi; R Joshi, M Gaspari, L Saso, AK Prasad, RC Rastogi

and VS Parmar

Scientific World Journal 2014, 578956/1-578956/10,10.

38. Revisiting a protocol for extraction of mycobacterial lipids.

P Singh, G Tyagi, P Khatri, NK Saini, R Pathak, M Varma-Basil, R Sinha, R Tandon, CSL Reddy and AK

Prasad International journal of mycobacteriology 2014, 3, 168-172.

39. Cytotoxic and Radio-sensitizing Effects of Polyphenolic Acetates in a Human Glioma Cell Line (BMG-1).

A Verma, K Venkateswaran, A Farooque, AN Bhatt, N Kalra, A Arya, A Dhawan, MB Arya, HG Raj and AK

Prasad

Current Pharmaceutical Design 2014, 20, 1161-1169.

40. Multi-component one-pot synthesis of novel coumarinyldihydro-pyridines under solvent free conditions.

K Bohra, D Sharma, B Kumar, CE Olsen, VS Parmar and AK Prasad

J. Ind. Chem. Soc. 2013, 90, 1885-1891.

41. One-pot Multi-component Synthesis of Coumarinyldihydro-pyrimidinones via Biginelli Condensation.

A Arya, V Khatri, K Mahiya, CE Olsen and AK Prasad

Curr. Org. Chem. 2013, 10, DOI: 10.2174/15701794113106660075.

42. Chemo-enzymatic synthesis of 3'-deoxy-3'-(4-substitutedtriazol-1-yl)-5-methyluridine.

A Arya, D Mathur, A Tyagi, R Kumar, V Kumar, CE Olsen, RK Saxena and AK Prasad.

Nucleosides, Nucleotides and Nucleic Acids 2013, 32, 646-659.

43. Modified Oligonucleotides: Strides towards Antisense Drugs.

VK Sharma, R Kumar, P Rungta, VS Parmar and AK Prasad

Trends Carbo Res. 2013, 5, 1-7.

44. Design and synthesis of LNA-based mercaptoacetamido-linked nucleoside dimmers.

VK Sharma, SK Singh, K Bohra, LCS Reddy, V Khatri, CE Olsen and AK Prasad

Nucleosides, Nucleotides and Nucleic Acids 2013, 32, 256-272.

45. Economical route for oxidative cleavage of double bond to synthesize taxol side chain.

S Bhatia, S Singh, R Kumar, A Kumar, A, CE Olsen and AK Prasad

Indian J. Chem. Section B 2013, 52, 379-386.

46. Sugar-Modified Mercaptoacetamido-linked Nonionic Nucleoside Dimer.

VK Sharma, A Tyagi, A Singh, P Rungta and AK Prasad

Trends Carb. Res. 2013, 5, 35-42.

47. Stereocontrolled oxidative additions upon 1,4-dihydropyridines: Synthesis of hexahydrofuro[2,3-b[pyridine and

hexahydropyrano[2,3-b]pyridine derivatives.

R Kumar, D Kumar and AK Prasad

Synthetic Communications 2013, 43, 520-536.

48. Calreticulin transacetylase mediated upregulation of thioredoxin by 7,8-diacetoxy-4-methylcoumarin enhances

the antioxidant potential and the expression of vascular endothelial growth factor in peripheral blood

mononuclear cells.

R Joshi, A Kumar, S Manral, R Sinha, S Arora, A Sharma, S Goel, N Kalra, S Chatterji, BS Dwarakanath, DS

Rawat, AL DePass, V Rohila, D Saluja, VS Parmar, AK Prasad and HG Raj.

Chemico-Biological Interactions 2013, 206, 327-336.

49. Synthesis and antimicrobial activity of pyrimidine chalcones.

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R Kumar, J Arora, AK Prasad, N Islam and AK Verma

Med. Chem. Res. 2013, 22, 5624-5631.

50. Ethyl 3',4',5'-trimethoxythionocinnamate modulates NF-κB and Nrf2 transcription factors.

S Kumar, BK Singh, AK Prasad, VS Parmar, S Biswal and B Ghosh

Eur. J. Pharmaco. 2013, 700, 32-41.

51. A novel cinnamate derivative attenuates asthma features and reduces bronchial epithelial injury in mouse

model.

S Kumar, U Mabalirajan, R Rehman, BK Singh, VS Parmar, AK Prasad, S Biswal and B Ghosh

International Immunopharmacology 2013, 15, 150-159.

52. Calreticulin transacetylase mediated upregulation of thioredoxin by 7,8-diacetoxy-4-methylcoumarin enhances

the antioxidant potential and the expression of vascular endothelial growth factor in peripheral blood

mononuclear cells.

R Joshi, A Kumar, S Manral, R Sinha, S Arora, A Sharma, S Goel, N Kalra, S Chatterji, BS Dwarakanath, DS

Rawat, AL Depass, V Rohil, D Saluja, VS Parmar, AK Prasad and HG Raj

Chemico-biological interactions 2013, 206, 327-336.

53. Selective biocatalytic acylation studies on 5-O-(4,4′- Dimethoxytrityl)-2,3-secouridine: An efficient synthesis of

UNA monomer.

SK Singh, LCS Reddy, S Srivastava, CE Olsen, YS Sanghvi, N Langkjær, J Wengel, VS Parmar and AK

Prasad Nucleosides, Nucleotides and Nucleic Acids 2012, 31, 831-840.

54. O-Aryl α,β-d-ribofuranosides: synthesis & highly efficient biocatalytic separation of anomers and evaluation of

their Src kinase inhibitory activity.

RK Sharma, S Singh, R Tiwari, D Mandal, CE Olsen, VS Parmar, K Parang and AK Prasad

Bioorg. Med. Chem. 2012, 20, 6821-6830.

55. Aryl alkyl ketones, benzophenones, desoxybenzoins and chalcones inhibit TNF-α induced expression of ICAM-

1: Structure-activity analysis.

S Kumar, LCS Reddy, Y Kumar, A Kumar, BK Singh, V Kumar, S Malhotra, MK Pandey, R Jain, R

Thimmulappa, SK Sharma, AK Prasad, S Biswal, EV Eycken, AL DePass, SV Malhotra, B Ghosh and VS

Parmar.

Archiv der Pharmazie 2012, 345, 368-377.

56. Design, synthesis and biological activity evaluation of regioisomeric spiro-(indoline-isoxazolidines) in the

inhibition of TNF-α-induced ICAM-1 expression on human endothelial cells.

S Malhotra, S Balwani, A Dhawan, Raunak, Y Kumar, BK Singh, CE Olsen, AK Prasad, VS Parmar and

B Ghosh

Med. Chem. Comm. 2012, 3, 1536-1547.

57. In vitro platelet antiaggregatory properties of 4-methylcoumarins

K MacÁková, Z Řeháková, P Mladěnka, J Karlíčková, T Filipský, M Říha, AK Prasad, VS Parmar, L Jahodář,

P Pávek, R Hrdina and L Saso

Biochimie 2012, 94, 2681-2686.

58. DAMTC regulates cytoskeletal reorganization and cell motility in human lung adenocarcinoma cell line: An

integrated proteomics and transcriptomics approach

A Goel, R Chhabra, S Ahmad, AK Prasad, VS Parmar, B Ghosh and N Saini

Cell Death and Disease 2012, 3, e402.

59. Synthesis and Conformational Analysis of Fluorinated Pipecolic Acids

S Singh, CM Martinez, S Calvet-Vitale, AK Prasad, T Prangé, PI Dalko and H Dhimane

Synlett 2012, 23, 2421-25.

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60. Stereocontrolled oxidative additions upon N-alkyl-1,4-dihydropyridines: Synthesis of hexahydrofuro[2,3-

b]pyridine derivatives

R Kumar, D Kumar and AK Prasad

Indian J. Chem. Sect. B 2012, 51, 1123-1130.

61. Sugar-PEGylated polymers for drug delivery applications

S Bhatia, K Bohra, M Kumar, C Mukesh and AK Prasad

Trends in Carbohydrate Research 2012, 4, 1-9.

62. Calreticulin transacetylase mediated activators of human platelet nitric oxide synthase by acetyl group donor

compounds.

A Kumar, S Sushama, S Manral, S Sinha, R Joshi, U Singh, V Rohil, AK Prasad, VS Parmar and HG Raj.

Nitric Oxide: Biology and Chemistry 2012, 26, 9-19.

63. Biocatalytic Route to Sugar-PEG-Based Polymers for Drug Delivery Applications.

S Bhatia, A Mohr, D Mathur, VS Parmar, R Haag and AK Prasad

Biomacromolecules, 2011, 12, 3487-3498.

64. Biocatalytic Deacylation Studies on Tetra-O-acyl-β-D-xylofuranosyl Nucleosides: Synthesis of xylo-LNA

Monomers.

SK Singh, VK Sharma, K Bohra, CE Olsen and AK Prasad

J. Org. Chem. 2011, 76, 7556-7562.

65. Characterization of 7-amino-4-methylcoumarin as an effective antitubercular agent: structure–activity

relationships.

R Tandon, P Ponnan, N Aggarwal, R Pathak, AS Baghel, G Gupta1, A Arya, M Nath, VS Parmar, HG Raj, AK

Prasad and M Bose

J. Antimicrob. Chemother. 2011, 66, 2543-2555.

66. Characterization of a unique dihydropyrimidinone, ethyl 4-(4_-heptanoyloxyphenyl)-6-methyl-3,4-

dihydropyrimidin-2-one-5-carboxylate, as an effective antithrombotic agent in a rat experimental model. 1316

N Priya, P Singh, S Bhatia, B Medhi, AK Prasad, VS Parmar and HG Raj.

J. Pharma. Pharmacol. 2011, 63, 1175-1185.

67. Chemical constituents of the Genus Prunus and their medicinal properties.

V Poonam, Raunak, G Kumar, LCS Reddy, R Jain, SK Sharma, AK Prasad and VS Parmar

Current Medicinal Chemistry, 2011, 18, 3758-3824.

68. Coumarins as antioxidants.

I Kostova, S Bhatia, P Grigorov, S Balkansky, VS Parmar, AK Prasad and L Saso

Current Medicinal Chemistry, 2011, 18, 3929-3951.

69. Normalization of deranged signal transduction in lymphocytes of COPD patients by the novel calcium channel

blocker H-DHPM.

S Manral, S Bhatia, R Sinha, A Kumar, V Rohil, A Arya, A Dhawan, P Arya, R. Joshi, SC Sreedhara, S

Gangopadhyay, SK Bansal, S. Chatterjee, NK Chaudhury, VK Vijayan, L Saso, VS Parmar, AL DePass, AK

Prasad, HG Raj

Biochimie 2011, 93, 1146-1156.

70. Selective Biocatalytic Aminolysis of (±)-Epichlorohydrin: Synthesis and ICAM-1 Inhibitory Activity of (S)-(+)-

3-Arylamino-1-chloropropan-2-ols.

P Kumar, S Bhatia, A Dhawan, S Balwani, S Sharma, R Brahma, RP Singh, B Ghosh, VS Parmar & AK

Prasad Bioorg. Med. Chem. 2011, 19, 2263-2268.

71. Short- and long-term regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase by a 4-methylcoumarin.

L Trapani, M Segatto, V Simeoni, V Balducci, A Dhawan, VS Parmar, AK Prasad, L Saso, S Incerpi and V

Pallottini.

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Biochimie, 2011, 93(7), 1165-1171.

72. Prevention of benzene-induced genotoxicity in bone marrow and lung cells: Superiority of polyphenolic

acetates to polyphenols.

A Kumar, A Sushama, V Rohil, S Manral, S Gangopadhyay, AK Prasad, HG Raj and VS Parmar.

Archives of Toxicology, 2011, 85(9), 1141-1150.

73. Characterization of protein acyltransferase function of recombinant purified GlnA1 from Mycobacterium

tuberculosis: A moon lighting property.

AS Baghel, R Tandon, G Gupta, A Kumar, RK Sharma, N Aggarwal, A Kathuria, NK Saini, M Bose, AK

Prasad, SK Sharma, M Nath, VS Parmar and HG Raj.

Microbiological Research, 2011, 166(8), 662–672.

74. Protein acyltransferase function of purified calreticulin: The exclusive role of P-domain in mediating protein

acylation utilizing acyloxycoumarins and acetyl CoA as the acyl group donors.

P Singh, P Ponnan, N Priya, TK Tyagi, S Krishnan, M Gaspari, G Cuda, P Joshi, JK Gambhir, D Saluja, AK

Prasad, L Saso, RC Rastogi, VS Parmar and HG Raj.

Protein and Peptide Letters, 2011, 18(5), 507-517.

75. Synthesis and biological activity evaluation of N-protected isatin derivatives as inhibitors of ICAM-1 expression

on human endothelial cells.

S Malhotra, S Balwani, A Dhawan, BK Singh, S Kumar, R Thimmulappa, S Biswal, CE Olsen, EV Eycken,

AK Prasad, B Ghosh and VS Parmar.

Med. Chem. Commun. 2011, 2, 743-751.

76. Selective biocatalytic aminolysis of (±)-epicholorohydrin: Synthesis and ICAM-1 inhibitory activity of (S)-(+)-

3-arylamino-1-chloropropan-2-ols.

P Gupta, S Bhatia, A Dhawan, S Balwani, S Sharma, R Brahma, R Singh, B Ghosh, VS Parmar and AK

Prasad.

Bioorg. Med. Chem. 2011, 19, 2263-2268.

77. Oxidative additions with 1,4-dihydropyridines: A one-pot synthesis of 3,4,4a,5,8,8a-Hexahydro-2H-pyrido[3,2-

b][1,4] oxazine derivatives.

R Kumar, S Malik, D Kumar and AK Prasad.

Synthetic Communication, 2011, 41, 2719-2726.

78. Stereocontrolled oxyselenation studies on 1,4-dihydropyridines. Synthesis of trans-2-hydroxy-(or alkoxy)-3-

phenylseleno-1,2,3,4-tetrahydropyridines.

R Kumar, D Kumar, AK Prasad.

Synthetic Communications 2011, 41, 2640-2648.

79. Diastereoselective acetylation studies on 4-C-hydroxymethyl-1,2-O-isopropylidene-3-O-alkyl-b-L-

threopentofuranose: key precursor for biocompatible sugar-PEG copolymers.

D Mathur, K Bohra, S Bhatia, M Kumar, P Verma, RK Saxena, VS Parmar and AK Prasad.

Trends in Carbohydrate Research 2011, 3, 42-50.

80. Potent inhibition of pandemic influenza H1N1 (2009) virus propagation by novel chemically synthesized

compounds.

M Khanna, R Rajput, P Kumar, D Sharma, D Mathur and AK Prasad.

Influenza and Other Respiratory Viruses 2011, 5, 96-99.

81. 7,8-Siacetoxy-4-methylcoumarin induced cell death in human tumor cells is influenced by calreticulin.

A Verma, AN Bhatt, A Farooque, S Khanna, D Khaitan, MB Arya, A Arya, A Dhawan, HG Raj, D Saluja, AK

Prasad, VS Parmar and BS Dwarkanath.

Biochimie 2011, 93, 497-505.

82. Novel natural product-based cinnamates and their thio & thiono analogs as potent inhibitors of cell adhesion

molecules on human endothelial cells.

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S Kumar, BK Singh, P Arya, S Malhotra, R Thimmulappa, AK Prasad, EV Eycken, CE Olsen, AL DePass, S

Biswal, VS Parmar and B Ghosh.

Eur. J. Med. Chem. 2011, 46(11), 5498-5511.

83. Biocatalytic separation of N-7/N-9 guanine nucleosides.

SK Singh, VK Sharma, CE Olsen, J Wengel, VS Parmar and AK Prasad

J. Org. Chem. 2010, 75, 7932-7935.

84. Structure-activity relationship of dihydroxy-4-methylcoumarins as powerful antioxidants: Correlation between

experimental & theoretical data and synergistic effect.

VD Kancheva, L Saso, PV Boranova, A Khan, MK Saroj, MK Pandey, S Malhotra, JZ Nechev, SK Sharma,

AK Prasad, MB Georgieva, C Joseph, AL DePass, RC Rastogi and VS Parmar.

Biochimie 2010, 92, 1089-1100.

85. Antioxidant properties of 4-methylcoumarins in in vitro cell-free systems.

M Giuseppa, T Domenico, BK Singh, AK Prasad, VS Parmar, N Clara, M Ferdinando, S Antonina, C

Mariateresa, F Omidreza and L Saso.

Biochimie 2010, 92, 1101-1107.

86. Advances in biomolecular and medicinal chemistry.

AK Prasad, VS Parmar, HG Raj, D Jore.

Biochimie 2010, 92, v-vi.

87. Derivatives of aryl amines containing the cytotoxic 1,4-dioxo-2-butenyl pharmacophores.

A Jha, C Mukherjee, AK Prasad, VS Parmar, M Vadaparti, U Das, E De Clercq, J Balzarini, JP Stables, A

Shrivastava, RK Sharma and JR Dimmock.

Bioorg. Med. Chem. Lett. 2010, 20, 1510-1515.

88. In vitro interactions of coumarins with iron.

P Mladenka, K Macakova, L Zatloukalova, Z Rehakova, BK Singh, AK Prasad, VS Parmar, L Jahodar, R

Hrdina and L Saso.

Biochimie 2010, 92, 1108-1114.

89. Calreticulin transacetylase catalyzed modification of the TNF-α mediated pathway in the human peripheral

blood mononuclear cells by polyphenolic acetates.

U Singh, A Kumar, R Sinha, S Manral, S Arora, S Ram, RK Mishra, P Gupta, SK. Bansal, AK Prasad, S

Biswal, VS Parmar and HG Raj.

Chemico-Biological Interactions 2010, 185, 263–270.

90. A spectro-electrochemical and chemical study on oxidation of 7,8-dihydroxy-4-methylcoumarin (DHMC) and

some related compounds in aprotic medium.

R Petrucci, L Saso, V Kumar, AK Prasad, SV Malhotra, VS Parmar and G Marrosu.

Biochimie 2010, 92, 1123-1129.

91. 4-Methylcoumarins as antioxidants: Scavenging of peroxyl radicals and inhibition of human low-density

lipoprotein oxidation.

F Natella, B Lorrain, AK Prasad, VS Parmar, L Saso and C Scaccini.

Biochimie 2010, 92, 1147-1152.

92. Novel chemoenzymatic methodology for the regioselective glycine loading on polyhydroxy compounds.

S Malhotra, M Calderon, AK Prasad, VS Parmar and R Haag.

Org. Biomol. Chem. 2010, 8, 2228-2237.

93. Synthesis, Src kinase inhibitory & anticancer activities of substituted 3-(N-alkyl-N-phenylamino)propane-2-ols.

D Sharma, RK Sharma, S Bhatia, R Tiwari, D Mandal, J Lehmann, K Parang, CE Olsen, VS Parmar and AK

Prasad.

Biochimie 2010, 92, 1164-1172.

Akpcv/10

94. Calreticulin transacylase: Genesis, mechanism of action and biological applications.

R Kumari, S Bansal, G Gupta, S Arora, A Kumar, S Goel, P Singh, P Ponnan, N Priya, TK Tyagi, AS Baghel, S

Manral, R Tandon, R Joshi, V Rohil, M Gaspari, E Kohli, YK Tyagi, BS Dwarkanath, D Saluja, S Chatterji, SK

Sharma, AK Prasad, RC Rastogi, HG Raj and VS Parmar.

Biochimie 2010, 92, 1173-1179.

95. β-Sitosterol among other secondary metabolites of Piper galeatum shows inhibition of TNFα-induced cell

adhesion molecule expression on human endothelial cells.

P Gupta, S Balwani, S Kumar, N Aggarwal, M Rossi, S Paumier, F Caruso, P Bovicelli, L Saso, AL DePass,

AK Prasad, VS Parmar and B Ghosh.

Biochimie 2010, 92, 1213-1221.

96. Protein acyltransferase function of purified clareticulin. Part 1: characterization of propionylation of protein

utilizing propoxycoumarin as the propionyl group donor.

P Singh, P Ponnan, S Krishnan, TK Tyagi, N Priya, S Bansal, D Scumaci, M Gaspari, G Cuda, P Joshi, JK

Gambhir, D Saluja, AK Prasad, L Saso, RC Rastogi, VS Parmar and HG Raj

J. Biochemistry 2010, 147, 625-632.

97. Enantioselective biocatalytic reaction on (±)-aryl alkyl ketones with native and modified porcine pancreatic

lipase.

M Husain, V Kumar, R Kumar, NA Shakil, SK Sharma, AK Prasad, CE Olsen, RK Gupta, SV Malhotra, E

Van Der Eycken, AL Depass, K Levon and VS Parmar

Biocat. Biotrans. 2010, 28, 172-184.

98. Prospects for the development of polyphenolic acetate as the potential drug candidate: A review. Compendium

of Bioactive Natural Products Vol. 7: Structural Modifications & Drug Development Bioactive Natural

Products.

HG Raj, A Kumar, R Kumari, S Bansal, P Ponnan, G Gupta, E Kohli, S Arora, AS Baghel, S Goel, R Gulati, U

Singh, R Tandon, D Saluja, BS Dwarakanath, AN Bhat, TK Tyagi, P Singh, N Priya, A Verma, V Rohil, AK

Prasad, A Vij, SK Bansal, VK Vijayan, SC Jain, RC Rastogi and VS Parmar.

Studium Press LLC, USA. 2010.

99. Chemoenzymatic modifications on D-glucose of bicyclonucleosides of therapeutic importance.

RK Sharma, D Mathur, S Singh, Kapil, RK Saxena, VS Parmar and AK Prasad.

Trend. Carbo. Res. 2010, 2, 1-9.

100. Synthesis and hybridization studies of α-configured arabino nucleic acids.

P Gupta, J Maity, G Shakya, AK Prasad, VS Parmar and J Wengal.

Org. Biomol. Chem., 2009, 7, 2389-2401.

101. Differential expression of Aspergillus fumigatus protein in response to treatment with a novel antifungal

compound, diethyl 4-(4-metho’phenyl-2,6-dimethyl-1 ,4-dihydropyridin- 3,5-dicarboxylate.

AK Chillar, V Yadav, A Kumar, M Kumar, VS Parmar, AK Prasad and GL Sharma.

Mycoses 2009, 52, 223-227.

102. Lipase-catalyzed regio- and stereoselective deacylation: Separation of anomers of peracylated α,β-D-

ribofuranosides.

RK Sharma, N Aggarwal, A Arya, CE Olsen, VS Parmar and AK Prasad.

Indian J. Chem. 2009, 48B, 1727-1731.

103. Synthesis and regioselective deacylation studies on peracylated 2′-azido arabino- and ribo-thymine

nucleosides: Towards 5′-O,2′-N-linked oligonucleotides.

D Sharma, A Khandelwal, RK Sharma, S Bhatia, CL Reddy, CE Olsen, J Wengel, VS Parmar and AK Prasad

Indian J. Chem. 2009, 48B, 1712-1720.

104. Specificities of caireticulin transacetylase to acetoxy derivatives of 3-alkyl-4-methylcoumarins: Effect

on the activation of nitric oxide synthase.

A Kathuria, A Gupta, N Priya, P Singh, HG Raj, AK Prasad, VS Parmar and SK Sharma.

Akpcv/11

Bioorg. Med. Chem. 2009, 17, 1550-1556.

105. Synthesis and lipase-catalysed enantioselective acylation studies on ethyl 4-aryl-3,4-dihydropyrimidin-

2(1H)-ones.

AK Prasad, P Arya, S Bhatia, RK Sharma, R Singh, BK Singh,

E Van der Eycken, R Singh, CE Olsen and VS Parmar.

Indian J. Chem. 2009, 48B, 1738-1748.

106. The role of caireticulin transacetylase in the activation of human platelet nitrite reductase by polyphenolic

acetates.

S Arora, YK Tyagi, A Kumar, S Majumder, D Saluja, HG Raj, S Chatterjee, L Saso, AK Prasad and VS

Parmar.

Biological and Pharmaceutical Bulletin 2009, 32, 161-165.

107. Autoacetylation of purified calreticulin transacetylase utilizing acetoxycoumarin as the acetyl group donor.

S Bansal, P Ponnan, HG Raj, ST Weintraub, M Chopra, R Kumari, D Saluja, A Kumar, TK Tyagi, P Singh, AK

Prasad, L Saso, RC Rastogi and VS Parmar.

Applied Biochemistry and Biotechnology 2009, 157, 285-298.

108. Apoptogenic effect of 7,8-diacetoxy-4-methylcoumarin and 7,8-diacetoxy-4-methylthiocoumarin in human lung

adenocarcinoma cell line: Role of NF-kB, Akt, ROS and MAP kinase pathway.

A Goel, AK Prasad, VS Parmar, B Ghosh and N Saini.

Chemico-Biological Interactions 2009, 179, 363-374.

109. Autoacetylation of purified calreticulin transacetylase utilizing acetoxycouma1n as the acetyl group donor.

S Bansal, P Ponnan, HG Raj, ST Weintraub, M Chopra, R Kumari, D Saluja, A Kumar, TK Tyagi, P Singh, AK

Prasad, L Saso, RC Rastogi and VS Parmar.

Applied Biochemistry and Biotechnology 2009, 152, 170-176.

110. Greener Biocatalytic Approach to the Synthesis of Nucleosides and their Precursors.

SK Singh, RK Sharma, J Maity, J Wengel, VS Parmar and AK Prasad

Nucleic Acids Symposium, 2008, 52, 273-274.

111. Antioxidant, antiinflammatory and antiinvasive activities of biopolyphenolics.

S Malhotra, G Shakya, A Kumar, BW Vanhoecke, AL Cholli, HG Raj, L Saso, B Ghosh, ME Bracke, AK

Prasad, S Biswal and VS Parmar.

ARKIVOC 2008 (vi), 119-139.

112. Efficient and selective enzymatic acylation reaction: Separation of furanosyl and pyranosyl nucleosides.

J Maity, G Shakya, S Singh, VT Ravikumar, VS Parmar and AK Prasad.

J. Org. Chem. 2008, 73, 5629-5632.

113. Synthesis and antimicrobial activity of 3-arylamino-1-chloropropan-2-ols.

AK Prasad, P Kumar, A Dhawan, AK Chhillar, D Sharma, V Yadav, M Kumar, HN Jha, CE Olsen, GL

Sharma and VS Parmar.

Bioorg. Med. Chem. Lett., 2008, 18, 2156–2161.

114. Extraction chromatography of lanthanides using N,N,N’,N’-tetraoctyldiglycolamide (TODGA) as the stationary

phase.

M Husain, SA Ansari, PK Mohapatra, RK Gupta, VS Parmar, AK Prasad and VK Manchanda

Desalination, 2008, 229, 294-301

115. Plant Polyphenolics as Anti-Invasive Cancer Agents

ME Bracke, BWA Vanhoecke, L Derycke, S Bolca, S Possemiers, A Heyerick, CV Stevens, DD Keukeleriem,

HT Depypere, W Verstraete, CA Williams, ST McKenna, S Tomar, D Sharma, AK Prasad, AL DePass and VS

Parmar.

Anticancer Agents in Medicinal Chemistry 2008, 8, 171-185.

Akpcv/12

116. Selective Biocatalytic Deacylation Studied on Furanose Triesters: A Novel and Efficient Approach Towards

Bicyclonucleosides.

AK Prasad, N Kalra, Y Yadav, Sunil K Singh, SK Sharma, S Patkar, L Lange, CE Olsen, J Wengel, and VS

Parmar,.

Org. Biomol. Chem. 2007, 5, 3524-3530.

117. E,E,E-1-(4-Arylamino-4-oxo-2-butenoyl)-3,5-bis(arylidene)-4-piperidones: A topographical study of some

novel potent cytotoxins.

A Jha, C Mukherjee, AK Prasad, VS Parmar, E DeClercq, J Balzarini, JP Stables, EK Manavathu, A

Shrivastav, RK Sharma, KH Nienaber, GA Zello and JR Dimmock.

Bioorg. Med. Chem. 2007, 15, 5854-5865.

118. Deacylation Studies on Furanose Triesters Using an Immobilized Lipase: Synthesis of a Key Precursor for

Bicyclonucleosides.

AK Prasad, N Kalra, Y Yadav, R Kumar, SK Sharma, S Patkar, L Lange, J Wengel and VS Parmar

Chem. Commun. 2007, 2616-2617.

119. Novel Selective Biocatalytic Deacylation Studies on Key Precursors for Bicyclonucleosides.

AK Prasad, SK Singh, N Kalra, N Singhal, J Wengel and VS Parmar

Nucleosides, Nucleotides & Nucleic Acids 2007, 26, 1517-1521.

120. Biocatalytic acylation studies on novel 3-aryl-3-hydroxymethyl1-2, 3-dihydo-4H-1-benzopyran-4-ones.

V Kumar, R Kumar, Raunak, Poonam, SK Sharma, AK Prasad, AL Cholli, CE Olsen and VS Parmar.

Indian J. Chem. 2007, 46B, 1501-1510.

121. 7,8-Dihydroxy-4-methylcoumarin induces apoptosis of human lung adenocarcinoma cells by ROS-independent

mitochondrial pathway through partial inhibition of ERK/MAPK signaling.

A Goel, AK Prasad, VS Parmar, B Ghosh and N Saini

FEBS Letters 2007, 581, 2447-2454.

122. A chromone analog inhibits TNF-α induced expression of cell adhesion molecules on human endothelial cells

via blocking NF-κB activation.

S Kumar, BK Singh, AK Pandey, A Kumar, SK Sharma, HG Raj, AK Prasad, E Van der Eycken, VS Parmar

and B Ghosh

Bioorg. Med. Chem. 2007, 15, 2952-2962.

123. Specificities of acetoxy derivatives of coumarins, biscoumarins, chromones, flavones, isoflavones and

xanthones for acetoxy drug: Protein transacetylase

A Kumar, BK Singh, NK Sharma, K Gyanda, SK Jain, YK Tyagi, AS Baghel, M Pandey, SK Sharma, AK

Prasad, SC Jain, RC Rastogi, HG Raj, AC Watterson, EV Eycken and VS Parmar.

Euro. J. Med. Chem. 2007, 42, 447-455.

124. Ellagic acid peracetates is superior to Ellagic acid in the prevention of genotoxicity due to aflatoxin B1 in bone

marrow and lung cells

A Kumar, YK Tyagi, Seema, P Ponnan, V Rohil, AK Prasad, BS Dwarkanath, VS Parmar and HG Raj

J. Pharm. Pharmaco. 2007, 59, 81-86.

119. Antioxidant activity of 4-methylcoumarins. JZ Pedersen, C Oliveria, S Incerpi, V Kumar, AM Fiore, PD Vito,

AK Prasad, SV Malhotra, VS Parmar and L Saso

J. Pharm. Pharmaco. 2007, 59, 1721-1728.

120. Novel selective biocatalytic deacetylation studies on dihydropyrimidinones

AK Prasad, C Mukherjee, SK Singh, R Brahma, R Singh, RK Saxena, CE Olsen and VS Parmar

J. Mol. Cat. B: Enzymatic 2006, 40, 93-100.

121. Extraction chromatographic studies of metal ions using N,N,N’,N’-tetraoctyl diglycolamide as the stationary

phase.

SA Ansari, PN Pathak, M Husain, AK Prasad, VS Parmar and VK Manchanda.

Akpcv/13

Talanta 2006, 68, 1273-1280.

122. Synthesis and lipase-catalyzed resolution studies on novel (+)-2-(2-acetoxyethyl)-4-arylmethyl-3-oxo-3,4-

dihydro-2H-1, 4-benzomazine-6-carboxylates

AK Prasad, C Mukherjee, D Sharma, S Rastogi, A Mangalam, A Jha, CE Olsen, SA Patkar and VS Parmar

J. Mol. Cat. B: Enzymatic 2006, 40 101-110.

123. Extraction of actinides using N,N,N',N'-tetraoctyl diglycolamide (TODGA): a thermodynamic study

SA Ansari, PN Pathak, M. Husain, AK Prasad, VS Parmar, VK Manchanda

Radiochim. Acta 2006, 94, 307-312.

124. Novel function of calreticulin: Characterization of calreticulin as a transacetylase-mediating protein acetylator

independent of acetyl CoA using polyphenolic acetates

HG Raj, R Kumar, Seema, G Gupta, R Kumar, D Saluja, KM Muralidhar, A Kumar, BS Dwarkanath, RC

Rastogi, AK Prasad, SA Patkar, AC Watterson and VS Parmar

Pure Appl. Chem. 2006, 78, 985-992.

125. Microwave-assisted synthesis of antimicrobial dihydropyridines and tetrahydropyrimidin-2-ones: Novel

compounds against aspergillosis

AK Chhillar, P Arya, C Mukherjee, P Kumar, Y Yadav, AK Sharma, V Yadav, J Gupta, R Dabur, HN Jha, AC

Watterson, VS Parmar, AK Prasad and GL Sharma

Bioorg. Med. Chem. 2006, 14, 973-981.

126. Biocatalytic Protecting Group Chemistry on Sugars, Nucleosides and their Analogs

AK Prasad and G Shakya

Biocatalysis: Chemistry and Biology, 2005, 65-81 (ISBN: 81-7736-286-0).

127. Novel Aromatic Ester from Piper longum and Its Analogues Inhibit Expression of Cell Adhesion Molecules on

Endothelial Cells

S Kumar, P Arya, C Mukherjee, BK Singh, N Singh, VS Parmar, AK Prasad and B Ghosh

Biochemistry 2005, 44, 15944-15952.

128. N,N,N’,N’-Tetraoctyl diglycolamide (TODGA): A promising extractant for actinide-partitioning from high-

level waste (HLW).

SA Ansari, PN Pathak, VK Manchanda, M Husain, AK Prasad and VS Parmar.

Solvent Extraction and Ion Exchange 2005, 23, 463-479.

129. Solvent-free biocatalytic amidation of carboxylic avids.

AK Prasad, M Husain, BK Singh, RK Gupta, VK Manchanda, CE Olsen and VS Parmar

Tetrahedron Letters 2005, 46, 4511-4514.

130. Mild, efficient, selective and “green” benzoylation of nucleosides using benzoyl cyanide in ionic liquid.

AK Prasad, V Kumar, J Maity, YS Sanghvi, VT Ravikumar and VS Parmar.

Nucleosides, Nucleotides and Nucleic Acids 2005, 24, 747-751.

131. Novel lipase-catalyzed enantioselective amidation of aliphatic acids

AK Prasad, M Husain, BK Singh, RK Gupta, VK Manchanda, CE Olsen and VS Parmar

Tetrahedron Letters, 2005, 46, 4511-4514.

132. “Green” Methodology for Efficient and Selective Benzoylation of Nucleosides using Benzoyl Cyanide in an

Ionic Liquid

AK Prasad, V Kumar, S Malhotra, VT Ravikumar, YS Sanghvi and VS Parmar

Bioorg. Med. Chem. 2005, 13, 4467-4472.

133. Benzoyl Cyanide: A Mild and Efficient Reagent for Benzoylation of Nucleosides

AK Prasad, V Kumar, J Maity, Z Wang, VT Ravikumar, Y Sanghvi and VS Parmar

Synthetic Communications, 2005, 35, 935–945.

Akpcv/14

134. Investigations toward new lead compounds from medicinally important plants

AK Prasad, V Kumar, P Arya, S Kumar, R Dabur, N Singh, AK Chhillar, GL Sharma, B Ghosh, J Wengel, CE

Olsen and VS Parmar.

Pure and Applied Chemistry 2005, 77, 25-40.

135. Microwave Mediated Synthesis of Spiro-(Indoline-isoxazolidines): Mechanistic Study and Biological Activity

Evaluation

Raunak, V Kumar, S Mukherjee, Poonam, AK Prasad, CE Olsen, SJC Schäffer, SK Sharma,

AC Watterson and

VS Parmar.

Tetrahedron, 2005, 61, 5687–5697.

136. Selective transacylation reactions on 4-aryl-3,4-dihydropyrimidin-2-ones and nucleosides mediated by novel

lipases.

Poonam, AK Prasad, C Mukherjee, G Shakya, GK Meghwanshi, J Wengel, RK Saxena and VS Parmar.

Pure and Applied Chemistry 2005, 77, 237–243.

137. Mechanism of biochemical action of substituted 4-methylcoumarins. Part 11: Comparison of the specificities of

acetoxy derivatives of 4-methylcoumarin and 4-phenylcoumarin to acetoxycoumarins: protein transacetylase

A Kumar, BK Singh, R Tyagi, SK Jain, SK Sharma, AK Prasad, HG Raj, RC Rastogi, AC Watterson and VS

Parmar

Bioorg. Med. Chem. 2005, 13, 4300-4305.

138. Biopolyphenolics as antioxidants: Studies under an Indo-Italian CSIR-CNR project.

MC Foti, SK Sharma, G Shakya, AK Prasad, G Nicolosi, P Bovicelli, B Ghosh, HG Raj, RC Rastogi and VS

Parmar.

Pure and Applied Chemistry 2005, 77, 91-101.

139. Production of a novel alkaline lipase by Fusarium globulosum using neem oil and its applications.

R Gulati, J Isar, V Kumar, AK Prasad, VS Parmar and RK Saxena.

Pure and Applied Chemistry, 2005, 77 251–262.

140. Novel nucleic acid architectures involving locked nucleic acid (LNA) and pyrene residues: Results from an

Indo-Danish collaboration.

BR Babu, Raunak, MD Sørensen, PJ Hrdlicka, S Trikha, AK Prasad, VS Parmar and J Wengel.

Pure and Applied Chemistry, 2005, 77, 319–326.

141. Novel thiocoumarins as inhibitors of TNF-α induced ICAM-1 expression on human umbilical vein endothelial

cells (HUVECs) and microsomal lipid peroxidation.

S Kumar, BK Singh, N Kalra, V Kumar, A Kumar, AK Prasad, HG Raj, VS Parmar and B Ghosh

Bioorg. Med. Chem. 2005, 13, 1605-1613.

142. Candida rugosa lipase-mediated enantioselective acetylation studies on (±)-3-arylmethyl-3-hydroxymethyl-2,3-

dihydro-4H-1-benzopyran-4-ones.

S Trikha, R Kumar, A Dhawan, Poonam, AK Prasad, AL Cholli, CE Olsen, AC Watterson and VS Parmar

Indian Journal of Chemistry, 2005, 44B, 356-365.

143. Synthetic and Biological Activity Evaluation Studies on Novel Isoxazolidines

S Mukherjee, Raunak, A Dhawan, Poonam, AK Prasad, CE Olsen, AL Cholli, W Errington,

HG Raj, AC Watterson and VS Parmar

Indian Journal of Chemistry, 2004, 43B, 2670-2682.

144. 1,4-Dihydroxyxanthone modulates the adhesive property of endothelial cells by inhibiting intercellular adhesion

molecule-1 (ICAM-1), vascular cell adhesion molecule-1 (VCAM-1) and E-selectin

B Madan, AK Prasad, VS Parmar and B Ghosh

Bioorg. Med. Chem. 2004, 12, 1431-1437.

145. Highly efficient and selective biocatalytic acylation studies on triazolylsugars,

A Bhattacharya, AK Prasad, J Maity, Himanshu, Poonam, CE Olsen, RA Gross and VS Parmar

Akpcv/15

Tetrahedron 2003, 59, 10269-10277.

146. Synthesis of novel poly(ethylene glycol) based amphiphilic polymers

K Danprasert, R Kumar, M H-Cheng P Gupta NA Shakil, AK Prasad, VS Parmar and J Kumar,

LA Samuelson, AC Watterson

European Polymer Journal 2003, 39, 1983–1990.

147. Highly Efficient Diastereoselective Biocatalytic Acylation of a Diastereotopic Furanose Diol and Synthesis of

Key Intermediates for Amino Derivatised Bicyclonucleosides

AK Prasad, S Roy, R Kumar, N Kalra, J Wengel,

C E Olsen, AL Cholli, LA Samuelson, J Kumar,

AC Watterson, RA Gross and VS Parmar

Tetrahedron 2003, 59, 1333-1338.

148. Synthetic and Biocatalytic Enantioselective Deacetylation Studies on Novel (+)-5/6/7-Acetoxy-4-aryl-3,4-

dihydrocoumarins

I Singh, AK Prasad, AK Sharma, RK Saxena, CE Olsen, AL Cholli, LA Samuelson, J Kumar,

AC Watterson and VS Parmar

Bioorg. Med. Chem. 2003, 11, 529-538.

149. Synthesis, Characterization and In Vitro Anti-invasive Activity Screening of Polyphenolic and Heterocyclic

Compounds

VS Parmar, NK Sharma, M Husain, AC Watterson, J Kumar, LA Samuelson, AL Cholli, AK Prasad, A

Kumar, S Malhotra, N Kumar, A Jha, A Singh, I Singh, Himanshu, A Vats, NA Shakil, S Trikha, S Mukherjee,

SK Sharma, SK Singh, A Kumar, HN Jha, CE Olsen, CP Stove, ME Bracke and MM Mareel

Bioorg. Med. Chem. 2003, 11, 913-929.

150. Mechanism of Biochemical Action of Substituted 4-Methylbenzopyran-2-ones. Part 10: Identification of the

Inhibitors for the Liver Microsomal Acetoxycoumarin: Protein Transacetylase

HG Raj, I Singh, E Kohli, R Kumari, G Gupta, YK Tyagi, A Kumar, AK Prasad, NK Kaushik, CE Olsen, AC

Watterson and VS Parmar

Bioorg. Med. Chem. 2003, 11, 1015-1019.

151. Naturally occurring aristolactams, aristolochic acids and dioxoaporphines and their biological activities

V Kumar, Poonam, AK Prasad and VS Parmar

Nat. Prod. Rep. 2003, 20, 565-583.

152. Novel biocatalytic esterification reactions on fatty acids: synthesis of sorbitol 1(6) monostearate.

R Gulati, P Arya, B Malhotra, AK Prasad, RK Saxena, J Kumar and AC Watterson.

Arkivoc, 2003, (iii), 159-170.

153. Synthetic, biocatalytic acetylation and anti-tuberculosis activity evaluation studies on (+)-4-alkyl-3,4-dihydro-3-

-hydroxyalkyl-2H-1,3-benzoxazines.

NA Shakil, A Dhawan, NK Sharma, V Kumar, S Kumar, M Bose, HG Raj, CE Olsen, AL Cholli,

LA Samuelson, J Kumar, AC Watterson, VS Parmar and AK Prasad.

Indian Journal of Chemistry, 2003, 42B, 1958-1969.

154. Synthesis of novel heterocyclic compounds: Routes to pyrazolyl 1,2,3-triazoles and their biological activity

evaluation

A Kumar, M Husain, AK Prasad, I Singh, A Vats, NK Sharma, SK Sharma, RK Gupta, CE Olsen,

ME Bracke, RA Gross and VS Parmar

Indian Journal of Chemistry, 2003, 42B, 1950-1957.

155. Conformationally locked Aryl-C-Nucleosides: Synthesis of phosphoramidite monomers and incorporation into

single stranded DNA and LNA (Locked Nucleic Acid)

BR Babu, AK Prasad, S Trikha, N Thorup, VS Parmar and J Wengel

J. Chem. Soc., Perkin Trans. I, 2002, 2509-2519.

Akpcv/16

156. Selective enzymatic epoxidation of dienes: generation of functional enantiomerically enriched diene

monoepoxy monomers.

S Hu, P Gupta, AK Prasad, RA Gross & VS Parmar

Tetrahedron Lett., 2002, 43, , 6763 - 6766.

157. Local Disruption of DNA-base Stacking by Bulky Base Surrogates.

I Singh, W Hecker, AK Prasad, VS Parmar and O Seitz

Chem. Commun. 2002, 500-501.

158. Established of the enzymatic protein acetylation independent of acetyl CoA: recombinant glutatione S-

transferase 3-3 is acetylated by a novel membrane-bound transcetylase using 7,8-diacetoxy-4-methyl coumarin

as the acetyl donor.

E Kholi M Gaspari, HG Raj, VS Parmar, JVD Greef, G Gupta, R Kumri, AK Prasad, S Goel, G Pal, YK Tyagi,

SC Jain, N Ahmad, AC Watterson, CE Olsen

FEBS Lett. 2002, 530, 139-142.

159. Xanthones as Inhibitors of Microsomal Lipid Peroxidation and TNF- Induced ICAM-1 Expression on Human

Umbilical Vein Endothetial cells (HUVECS)

B Madan, I singh, A kumar, AK Prasad, HG Raj, VS Parmar and B Ghosh

Bioorg. Med. Chem. 2002, 10, 3431-3436.

160. Chemical Constituents of Cephalotaxus Species

A Bhattacharya, VS Parmar, SK Sharma, S Trikha, SK Singh and AK Prasad

J. Indian Chem. Soc. 2002, 79, 787-795.

161. Mechanism of Biochemical Action of Substituted 4-Methylbenzopyran-2-ones. Part 9: Comparison of Acetoxy

4-Methylcoumarins and other Polyphenolic acetates Reveal the Specificity to Acetoxy Drug: Protein

Transacetylase for Pyran Carbonyl Group in Proximity to the Oxygen Heteroatom

I Singh, E Kohli, HG Raj, K Gyanda, SK Jain, YK Tyagi, G Gupta, R Kumari, A Kumar, GK Pal, AK Prasad,

RC Rastogi,CE Olsen,SC Jain and VS Parmar

Bioorg. Med. Chem. 2002, 10, 4103-4111.

162. Synthesis and Antiviral Activity Evaluation of Novel 2-Phenyl-4-(D-arabino-4'-cycloaminobutyl) triazoles:

Acyclonucleosides Containing Unnatural Bases

Himanshu, R Tyagi, CE Olsen, W Errington, VS Parmar and AK Prasad

Bioorg. Med. Chem., 2002, 10, 963-968.

163. Novel Lipase-catalysed Highly Selective Acetylation Studies on D-Arabino- and D-Threo-

polyhydroxyalkyltriazoles

AK Prasad, Himanshu, A Bhattacharya, CE Olsen and VS Parmar

Bioorg. Med. Chem. 2002, 10, 947-951.

164. Chemical Transformations on 6-Aryl-3-cyano-4-methylthio-pyran-2(H)-ones: Synthetic and Structural Studies

on Novel N-Phenylpyrazoles and N-Phenylpyrazolylcoumarins

A Kumar, S Malhotra, A Vats, Himanshu, SK Singh, SK Sharma, AK Prasad, W Errington, CE Olsen, SC Jain

and VS Parmar.

Indian J. Chem. 2002, 41B, 360-367.

165. Seminal Findings on a Novel Enzyme: Mechanism of Biochemical Action of 4-Methylcoumarins, Constituents

of Medicinal and Edible Plants

VS Parmar, HG Raj, AK Prasad, SC Jain, CE Olsen and AC Watterson

Biodiversity: Biomolecular Aspect of Biodiversity and Innovative Utilization, Ed. Bilge Sener, Kluwer

Academic Publishers, 2002, 101-108.

166. Comparison of the prevention of aflatoxin-B1-induced genotoxicity by quercetin and quercetin pentaacetate

E Kohli, HG Raj, R Kumari, V Rohil, NK Kaushik, AK Prasad and VS Parmar

Bioorg. Med. Chem. Lett. 2002, 12, 2579-2582.

Akpcv/17

167. Synthesis and Lipase-mediated Stereoselective Deacetylation of (+)-3-Acetoxymethyl -3-alkyl-7-

methoxychroman-4-ones

Poonam, AK Prasad, A Azim, R Kumar, CE Olsen, W Errington, SC Jain and VS Parmar

Tetrahedron 2001, 57, 7395-7402.

168. Lipase-catalysed Chemo- and Enantioselective Acetylation of 2-Alkyl/aryl-3-hydroxypropiophenones

Rajesh Kumar, Abul Azim, Vijayendra Kumar, Sunil K Sharma, Ashok K Prasad, Oliver W Howarth, Carl E

Olsen, Subhash C Jain and Virinder S Parmar

Bioorg. Med. Chem. 2001, 9, 2643-2652.

169. Novel Lipase-catalysed Enantioselective Deacetylation of (+)-5-Acetoxy-3-(4-fluoro-phenyl)-2-

phenylisoxazolidine

S Mukherjee, AK Prasad, VS Parmar and OW Howarth

Bioorg. Med. Chem. Lett. 2001, 11, 2117-2121.

170. Selective Biotransformation Reactions on (+)-Aryl Alkyl Ketones, (+)-Benzoxazines, and D-Arabino- and D-

Threo-hydroxyalkyltriazoles.

Raunak, AK Prasad, NA Shakil, Himanshu and VS Parmar

Pure and Appl. Chem. 2001, 73, 167-174.

171. Biocatalytic Potential of Fusarium globulosum Lipase in Selective Acetylation/Deacetylation Reactions and in

Ester Synthesis

R Gulati, A Bhattacharya, AK Prasad, R Gupta, VS Parmar and RK Saxena.

J. Appl. Microb. 2001, 90, 609-613.

172. Synthetic and Biological Activity Evaluation Studies on Novel 1,3-Diarylpropenones

S Mukherjee, V Kumar, AK Prasad, HG Raj, ME Bracke, CE Olsen, SC Jain and VS Parmar

Bioorg. Med. Chem. 2001, 9, 337-345.

173. Enzymatic Enantioselective Deacetylation Studies on Novel (+)-2,4-Diacetoxyphenyl Alkyl Ketones

NA Shakil, A Singh, AK Prasad, V Kumar, CE Olsen, SC Jain, AL Cholli, AC Watterson and VS Parmar

J. Macromol. Sci.-PAC 2001, A38, 1275-90.

174. Synthetic and Biotransformation Studies on Prochiral Non-proteinogenic Amino Acid: Diethyl -Acetamido, -

Alkylmalonates

A Singh, AK Prasad, W Errington, YN Belokon, KA Kochetkov, RK Saxena, SC Jain and VS Parmar.

Indian J. Chem. 2000, 39B, 10-15.

175. Mass Fragmentation Pattern of (Z)-2-(5-arylpyrazole-3-yl)-3-arylacrylonitriles

VS Parmar, SK Singh, AK Prasad, A Jha, A Kumar and KR Jenning

Indian J. Chem. 2000, 39B, 915-920.

176. Synthesis of E- and Z-Pyrazolylacrylonitriles and their Evaluation as Novel Antioxidants

VS Parmar, A Kumar, AK Prasad, SK Singh, N Kumar, S Mukherjee, HG Raj, S Goel, W Errington and MS

Puar

Bioorg. Med. Chem. 1999, 7, 1425-1436.

177. Enzymatic Regio- and Enantioselective Deacetylation of 2,4-Diacetoxyphenyl Alkyl Ketones

AK Prasad, HN Pati, A Azim and Poonam

Bioorg. Med. Chem. 1999, 7, 1973-1977.

178. Enzyme-catalysed Chemoselective Transesterification Reactions on Hydroxymethylated Phenolic

Compounds

VS Parmar, AK Prasad, HN Pati, R Kumar, A Azim, S Roy and W Errington

Bioorg. Chem. 1999, 27, 119-134.

179. A New Amide, N-Cinnamoylpyrrole from Piper argyrophyllum

S Gupta, A Jha, AK Prasad, VK Rajwanshi, SC Jain, CE Olsen, J Wengel and VS Parmar

Akpcv/18

Indian J. Chem. 1999, 38B, 823-827.

180. Nucleoside Synthesis Mediated by Glycosyl Transferring Enzymes

AK Prasad, Smriti Trikha and VS Parmar

Bioorg. Chem. 1999, 27, 134-154.

181. Lipase-catalysed Selective Deacetylation of Phenolic/Enolic Acetoxy Groups in Peracetylated Benzyl Phenyl

Ketones

VS Parmar, HN Pati, A Azim, R Kumar, Himanshu, KS Bisht, AK Prasad and W Errington

Bioorg. Med. Chem. 1998, 6, 109-118.

182. Synthesis and Anti-invasive Activity of Novel 1,3-Diarylpropenones

VS Parmar, SC Jain, KS Bisht, NK Sharma, Himanshu, S Gupta, AK Prasad, A Jha, Poonam, S Malhotra, SK

Sharma, ME Bracke, W Errington, CE Olsen and J Wengel

Indian J. Chem. 1998, 37B, 628-643.

183. Novel Enzymatic De-esterification Studies on Substituted Polyacetoxybenzamides

VS Parmar, A Kumar, AK Prasad, R Kumar, KS Bisht, Poonam, SC Jain and CE Olsen

J. Indian Chem. Soc. 1998, 75, 810-822.

184. Combinatorial Approach Towards Synthesis of 2',3'-Dideoxynucleosides and Enzyme-catalysed Selective

Hydrolysis of Diethyl Acetamidomalonate and Amides of Polyacetoxy Aromatic Carboxylic Acids

A Kumar, A Singh, R Kumar, AK Prasad, VS Parmar, VI Tararov, YN Belokon, SK Singh and J Wengel

Indian J. Chem. 1997, 36A & B, 507-512.

185. Phytochemistry of the Genus Piper

VS Parmar, SC Jain, KS Bisht, R Jain, P Taneja, A Jha, OD Tyagi, AK Prasad, J Wengel, CE Olsen and PM

Boll

Phytochemistry 1997, 46, 597-673.

186. Novel Chemoselective De-esterification of Esters of Polyacetoxy Aromatic Acids by Lipases

VS Parmar, A Kumar, KS Bisht, S Mukherjee, AK Prasad, SK Sharma, J Wengel and CE Olsen

Tetrahedron 1997, 53, 2163-2176.

187. Enzyme-mediated Protecting Group Chemistry on the Hydroxyl Groups of Nucleosides

AK Prasad and J Wengel

Nucleosides Nucleotides 1996, 15, 1347-1359.

188. Novel Biotransformations on Peracylated Polyphenolics by Lipases Immobilized in Microemulsion-based Gels

and on Carbohydrates by Candida antarctica Lipase

VS Parmar, KS Bisht, HN Pati, NK Sharma, A Kumar, N Kumar, S Malhotra, A Singh, AK Prasad and J

Wengel

Pure and Appl. Chem. 1996, 68, 1309-1314.

189. Resorcinols and Catechols- A Clinical Study of Cross-Sensitivity

PM Boll, AK Prasad, KW Knight

Am. J. Cont. Derm. 1996, 7, 138-142.

190. Neolignans and Alkaloids from Piper argyrophyllum

SK Singh, AK Prasad, CE Olsen, A Jha, SC Jain, VS Parmar and J Wengel

Phytochemistry 1996, 43, 1355-1360.

191. Neolignans, Cyclohexanes and Alkaloids from Piper wightii

PM Boll, AK Prasad, OD Tyagi, J Wengel, CE Olsen, N Kumar, KS Bisht and VS Parmar

Recl. Trav. Chim. Pays-Bas 1995, 115, 9-12.

192. Tri-O-acyl 2-Deoxy-D-ribofuranose: An Effective Enzyme-assisted One-pot Synthesis from 2-Deoxy-D-ribose

and Transformations into 2'-Deoxynucleosides

Akpcv/19

AK Prasad, MD Sorensen, VS Parmar and J Wengel

Tetrahedron Lett. 1995, 36, 6163-6166.

193. Neolignans and a Lignan from Piper clarkii

AK Prasad, OD Tyagi, J Wengel, PM Boll, CE Olsen, KS Bisht, A Singh, A Sarangi, R Kumar, SC Jain and

VS Parmar

Phytochemistry 1995, 39, 655-658.

194. Methylenedioxyphenyl Substituted Compounds from Piper Species as Inhibitors of Liver Microsome-mediated

Aflatoxin B1-DNA Binding in vitro

HG Raj, S Gupta, AK Prasad, PM Boll, J Wengel, G Biswas, SK Singh, NK Sharma, KS Bisht and VS Parmar

Bioorg. Med. Chem. Lett. 1995, 5, 1567-1572.

195. Neolignans from Piper schmidtii and Reassignment of the Structure of Schmiditin

OD Tyagi, AK Prasad, J Wengel, PM Boll, CE Olsen, VS Parmar, NK Sharma, A Jha and KS Bisht

Acta Chem. Scand. 1995, 49, 142-148.

196. Lignans and Neolignans from Stems of Piper wightii

AK Prasad, OD Tyagi, J Wengel, PM Boll, CE Olsen, S Gupta, NK Sharma, KS Bisht and VS Parmar

Tetrahedron 1994, 50, 10579-10586.

197. Benzofuranoid Neolignans from Piper wightii Miq

OD Tyagi, J Wengel, AK Prasad, PM Boll, CE Olsen, HN Pati, KS Bisht and VS Parmar

Acta Chem. Scand. 1994, 48, 1007-1011.

198. Biotransformations in the Regioselective Deacetylation of Polyphenolic Peracetates in Organic Solvents

KS Bisht, OD Tyagi, AK Prasad, NK Sharma, S Gupta and VS Parmar

Bioorg. Med. Chem. 1994, 2, 1015-1020.

199. Lignans and Neolignans from Stems and Fruits of Piper wightii

AK Prasad, OD Tyagi, J Wengel, PM Boll, CE Olsen, NK Sharma, KS Bisht, S Gupta and VS Parmar

Tetrahedron 1994, 50, 2231-2240.

200. Some Recent Isolation Studies from Potential Insecticidal Piper Species

PM Boll, VS Parmar, OD Tyagi, AK Prasad, J Wengel and CE Olsen

Pure and Appl. Chem. 1994, 66, 2339-2342.

201. Lipase-catalysed Selective Deacetylation of Peracetylated Benzopyranones

VS Parmar, AK Prasad, NK Sharma, A Vardhan, HN Pati, SK Sharma and KS Bisht

Chem. Commun. 1993, 27-29.

202. Regioselective Esterification of Diols and Triols with Lipases in Organic Solvents

VS Parmar, R Sinha, KS Bisht, S Gupta, AK Prasad and P Taneja

Tetrahedron 1993, 49, 4107-4116.

203. Regioselective Enzyme-catalysed Deacetylation of Benzyl Phenyl Ketone Peracetates in Organic Solvents

VS Parmar, AK Prasad, NK Sharma, KS Bisht, HN Pati and P Taneja

Bioorg. Med. Chem. Lett. 1993, 3, 585-588.

204. Potential Applications of Enzyme-mediated Transesterifications in the Synthesis of Bioactive Compounds

VS Parmar, AK Prasad, NK Sharma, KS Bisht, R Sinha and P Taneja

Pure and Appl. Chem. 1992, 64, 1135-1139.

205. Regioselective Deacylation of Polyacetoxy Aryl-methyl Ketones by Lipases in Organic Solvents

VS Parmar, AK Prasad, NK Sharma, SK Singh, HN Pati and S Gupta

Tetrahedron 1992, 48, 6495-6498.

Akpcv/20

206. Lipase-catalysed Transesterifications using 2,2,2-Trifluoroethyl Butyrate: Effect of Temperature on Rate of

Reaction and Enantioselectivity

VS Parmar, AK Prasad, PK Singh and S Gupta

Tetrahedron: Asymmetry 1992, 3, 1395-1398.

207. New Antibacterial Tetratricontanol Derivatives from Agave americana L

VS Parmar, HN Jha, AK Gupta, AK Prasad and S Gupta

Tetrahedron 1992, 48, 1281-1284.

208. Agamanone, A Flavanone from Agave americana

VS Parmar, HN Jha, AK Gupta and AK Prasad

Phytochemistry 1992, 31, 2567-2568.

209. Regioselective Hydrolysis of Polyacetoxy Aromatic Ketones with Lipases in Organic Solvents

VS Parmar, CH Khanduri, OD Tyagi, AK Prasad, S Gupta, KS Bisht, HN Pati and NK Sharma

Indian J. Chem. 1992, 31B, 925-929.

210. Enzyme-mediated Hydrolytic Studies on Aminophenol Diacetates

VS Parmar, AK Prasad, OD Tyagi, S Gupta, R Sinha, S Gupta, A Chauhan and NA Shakil

Indian J. Chem. 1992, 31B, 903-905.

211. Synthesis of Isoflavanones from Isoflavones by Reduction with Sodium Hydrogen Telluride

AC Jain, NK Sharma and AK Prasad

Indian J. Chem. 1991, 30B, 290-291.

212. Synthesis of Amorilin (Euchrenone a3) and 5,7-Dihydroxy-6",6"-dimethyl-6,8-di-C-prenylpyrano [2",3",3',4']-

flavanone

AC Jain and AK Prasad

Indian J. Chem. 1990, 29B, 525-528.

213. Synthesis of Natural Triisopentenylated Flavanone, Euchrenone a2

AC Jain and AK Prasad

Proc. Indian Acad. Sci. 1989, 101, 467-472.

214. Synthesis of Naturally Occurring Pongagallone A, Pongagallone B and their Analogues

AC Jain and AK Prasad

Indian J. Chem. 1989, 28B, 193-194.

215. Synthesis of Naturally Occurring 6,7-Dimethoxy-3',4'-methylenedioxyisoflavanone and Its Analogues

AC Jain and AK Prasad

Indian J. Chem. 1988, 27B, 622-624.

216. Synthesis of Natural (+)-Dihydrocladrin, (+)-Homoferreirin and Related Isoflavanones

AC Jain, OD Tyagi and AK Prasad

Proc. Indian Acad. Sci. 1988, 100, 45-52.

217. Synthesis of 7,8-Dioxygenated Isoflavanones

AC Jain and AK Prasadr Indian J. Chem. 1987, 26B, 1143-1147.

Akpcv/21

PATENTS: 7

1. Regioselective Acylation of Nucleosides Ashok K Prasad, Virinder S Parmar, Rajendra K Saxena and Gaurav

Shakya, PCT: WO2011 / 030353 (International PCT Application No. PCT/IN2010/000594).

2. Regioselective Acylation of Nucleosides Ashok K Prasad, Virinder S Parmar, Rajendra K Saxena and Gaurav

Shakya, Indian Patent Application No. 1885/DEL/2009.

3. Dihydropyrimidinone compounds for the treatment of cardiovascular diseases and process for preparing the

same VS Parmar, HG Raj and Ashok K Prasad International Patent Application No. PCT/IN2009/000344.

4. Coumarin Compounds for the treatment of Cardiovascular diseases and a process for preparing the same VS

Parmar, HG Raj, SC Jain and Ashok K Prasad International Patent Application No. PCT/IN2009/000359.

5. Dihydropyrimidinone compounds for the treatment of cardiovascular diseases and process for preparing the

same VS Parmar, HG Raj and Ashok K Prasad Indian Patent Application 1414/DEL/2008.

6. Coumarin Compounds for the treatment of Cardiovascular diseases and a process for preparing the same VS

Parmar, HG Raj, SC Jain and Ashok K Prasad Indian Patent Application 1495/DEL/2008.

7. Coumarin Compounds for the Treatment of Mycobacterial Infections. Virinder S Parmar, Ashok K Prasad,

Sunil K Sharma, HG Raj, Rashmi Tandon and Mridula Bose International PCT Application No.

PCT/IN2012/000242.