adjust your seat…. hafdzi maulanaaang setiawantodia pediatama
TRANSCRIPT
Adjust your seat…
GET READY FOR WELCOMING US…
Assalamualaikum Wr. Wb.
Presented by :
Hafdzi Maulana
Aang Setiawan
Todia Pediatama
ANTI-HYPERTENSIVE AGENT OF CORN SILK EXTRACT AS PREVENTIVE METHOD
IN VASCULAR HYPERTENSIVE DISEASE
[TITLE]
LifestyleRisk Factorx
Background
LifestyleRisk Factor
Vascular HypertensiveDisease
severe
x
1. The Impact of Chronic Disease in Indonesia. Available from : http://www/who/int/chp/chronic_disease_report/en/. 2. Kumar, R., Abbas, A., DeLancey, A., and Malone, E. Robbin and Cotran Pathologic Basis of Disease. ed 8. US. 2010: 529-
585.3. Kasper, Braunwald, Fauci, Hauser, Longo and Jameson. Harrison’s Principles of Internal Medicine. ed 16. US. 2005:
1463-1480.4. Mycek, M.J., Harvey, R.A., and Champe, P.C. Lippincott’s Illustrated Reviews: Pharmacology. ed 2. US. p 157.
Objective
To describe and give basic understanding of corn silk as preventive method in VHD.
Benefit
For future research on providing deeper knowledge for effectiveness of corn silk.
Data Synthesis
Discussion
&
JurnalJurnal
Searching engine
Inclusion
Abstract
Result & Discussion
Keywords :
Output
Analyze
Exclude
Data Synthesis
Jurnal
Corn Silk
•Contain
Hypertension
• Etiology
Corn Silk
Hypertension
1. Taxonomy and Nomenclature of Zea Mays L. 2012; Available from: ttp://www.itis.gov/servlet/SingleRpt/SingleRpt?search_topic=TSN&search_value=422692. Maksimovic, Z., Malencic, D. and Kovacevic, N. (2005) Polyphenol contents and antioxidant activity of Maydis stigma extracts. Bioresource Technology 96, 873-877.
Zea mays
Classification
Morphology
Distribution
Usage
Zea mays or known as corn. From genus Zea L.. Species Zea mays L.(1)
LEAF
EAR
STALK
TASSEL
Corn Silk (maydis Stigma)
COB (kernels)
???
Treatment of Cystits, gout,
nephritis, benign prostatic
hyperplasia (2)
Corn Silk
Hypertension
[25]http://medical-dictionary.thefreedictionary.com/hypertension (10/3/2012)
Hypertension which is unknown cause called primary hypertension (also called essential and idiopathic hypertension), and hypertension which is known cause called secondary hypertension.
[26]Fauci, Anthony., Kasper, Denis., Harrison’s Internal Medicine.Ed.18.USA:McGraw-Hill’s.2009
Classification of Hypertension
[26]
No. Blood Pressure Classification
Systolic Diastolic
1. Normal <120 <80
2. Prehypertension (PH) 120-139 or 80-89
3. Stage 1 hypertension 140-159 or 90-99
4. Stage 2 hypertension ≥160 ≥100
5. Isolated systolic hypertension
≥140 <90
[29,30]
• Moser, Marvin. Heart Book. USA : Yale University. Shijiazhuang Kidney Disease Hospital. http://kidneycn.com (16/03/2012)
Criteria of People in High Risk of Hypertension
Obesity
Improper diet
SmokingLain-lain
Non-pharmacologic[31]
[31]Crawford, Michael. CURRENT Diagnosis & Treatment in CARDIOLOGY. Ed.2. USA: Mac Graw Hill.[32]Antonello, Michele., Montemuro, Domenico., Bolognesi, Massimo., Pasoli, Di Marco., Piva, Anna., Grego, Franco., Sticchi, Danielle., Giuliani, Luisa., Garbisa, Spiridro. and Rossi, Gian Paolo. 2007. Prevention of Hypertension, Cardiovascular Damage & Endothelial Dysfunction with Green Tea Extracts.Italy.[15]Hu Q-L, Deng Z-H. Protective effects of flavonoid from corn silk on oxidative stress induced by exhaustive exercise in mice. African Journal of Biotechnology. 2011;10(16):3163-7.
Non-pharmaco &
Pharmacologic [31]
Green Tea[32] Corn Silk[15]
Treatments
Pharmacologic [31]
Back
High Risk
•Obese •Improper Diet•Diabetes•Smoking, etc.
High blood glucose adipogenesis
High LDL
High cholesterol
Atherosclerosis
Hypertension
Water & Na retention
Flavonoid
Tannic Acid
Fe+ chelating
Flavonoid & Sapponin
Minerals
Discussion
Conclusion
It has several compound and activity as anti-oxidant
agent, anti-inflammation, and anti-hyperlipidemia, that plays as hypertensive agent. Comparing to current preventive method e.g. green tea that works as anti-oxidant, corn silk is more effective to work. It is low-cost, and easy-found.
Further research is considerably recommended in Indonesia. Also, the research in effectiveness of corn silk should be held in future.