acute inflammation -...
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ACUTE INFLAMMATION
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Characteristic
• Course of disease:short Days--one month
• Changes : Alteration, exudationTissue destruction
• Inflammation cells: major neutrophils
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Serous Inflammation
Fibrinous Inflammation
Suppurative Inflammation
Hemorrhagic Inflammation
TYPES
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Serous inflammationConception : It is characterized by the
outpouring of a watery , relatively protein- poor fluid (effusion). The main content is serum.
Characteristic: Watery, low protein content, derived from blood or lymph fluid.
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•• Site:Site: mucous membrane, serosa, lung, loose connective tissue, skin.
•• Examples: Examples: skin blister resulting from burn, scalding or viral infection, pleural effusion associated with tuberculosis, common cold, etc.
Serous inflammation
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Serous inflammation(Skin blister)
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Serous inflammation
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Conception :It occurs as a consequence of more severe injuries, with greater vascular permeability allowing larger molecules ( fibrinogen ) to pass the endothelial barrier.
Fibrinous Inflammation
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Characteristic: lots of fibrin in the exudate.
Causes: ShigellosisStreptococcus pneumoniasCorynebacterium diphtheriasUremia
Fibrinous Inflammation
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Site :SerosaMucous membrane: Pseudo-membraneLung
Examples: rheumatic pericarditis, dysentery, diphtheria, lobular pneumonia, etc.
Fibrinous Inflammation
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Lobar pneumonia
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Lobar pneumonia
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Fibrinous Inflammation
Special disease:
“cor villosum ” --Fibrinous pericarditis hairy heart
Pseudo-membranous inflammation
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The epicardial surface of the heart shows a shaggy fibrinous exudate.
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Pseudomembranous inflammation:
site: occuring at the surface of mucosa (intestinal mucosa, throat, etc.)
Components : it consists of fibrin, neutrophils, necrotic mucosa epithelial cells and organism.
Fibrinous Inflammation
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pseudomembrane
Bile dyed the membrane yellow-green
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Pseudomembrane
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Resolution
Organization
Fibrinous Inflammation
Outcome
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Purulent / suppurative inflammation
Conception : It is manifested by the presence of large amounts of purulent exudate (pus) consisting of neutrophils, necrotic cells and edema fluid.
Pus composed of: dead and dying neutrophils, liquefied tissue, pyogenic organisms.
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Causes: staphylococci, pneumococcus, gonococci, gram- negative rods, and some nonhemolytic streptococci.
Types:(1) Abscess;(2) Phlegmonous inflammation; (3) Surface purulence(4) Empyema
Purulent / suppurative inflammation
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Abscess:It is a focal collection of pus and typically has a central, largely necrotic region with a surrounding zone of proliferated connective tissue, often companied with vomica formation.
It is often caused by staphylococci
Purulent / suppurative inflammation
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abscess
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Hepatic abscess
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Normal Hepatic abscess
hepatic cord
Sinus
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Outcome of abscessUlcer: a local defect on the surface of skin or
mucosa where an epithelial surface become necrotic and eroded.
Sinus: deep abscess perforated to body surface or body cavity to form a tract with one opening.
Fistula: a tract of pus discharge with more than one opening.
Cavity: a gap formed by necrotic tissue be drainaged from nature tract in visceral organs.
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Sinus
Fistula
form a tract with one opening.
a tract of pus discharge with two opening.
abscess
Anus
Anus
abscess
rectum
rectum
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Conception :Diffuse purulent inflammation process of soft tissue.
Cause: commonly by -hemolytic streptococcus.
Characteristic : Diffuse infiltration of neutrophils. Tissue necrosis is not obvious.
Site: Often occurred in subcutaneous tissue, muscle, appendix.
Phlegmonous inflammation
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phlegmonous appendicitis
Color, size, shape, surface
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Acute phlegmonous appendicitis
Diffuse infiltration of neutrophils
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Myocarditis
Diffuse infiltration of neutrophils
myocyte
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Surface purulence( purulent catarrh )
purulent inflammation of mucosa or surface of tissue.
Purulent / suppurative inflammation
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Purulent catarrh on the surface of meninges
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Purulent meningitis
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Empyema
purulent exudate cannot be effective drainaged and accumulated in body cavity or tract.
Example : intestinal duct, oviduct, gallbladder, thorax.
Purulent / suppurative inflammation
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Characteristic: Marked Hemorrhage, many
blood cells in inflammatory exudate.
Some severe infectious diseases:streptococcal pneumonia, pestis, epidemic hemorrhagic fever, etc.Endemic Hemorrhagic Fever SARS…
Hemorrhagic Inflammation
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Hemorrhagic inflammation