6th MantuaWORKSHOP on

DIABETES MELLITUSand Related Disorders

the future of diabetes care

Mantova (Italy)October 19-22, 2016

ENDOCRINOLOGIA, DIABETOLOGIA E METABOLISMO

UNIVERSITÀ DI VERONA

ACCADEMIA NAZIONALE VIRGILIANADI SCIENZE LETTERE E ARTI

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ChairmanEnzo Bonora (Italy)

Honorary ChairmanMichele Muggeo (Italy)

Scientific CommitteeRiccardo C. Bonadonna (Italy)Ralph A. DeFronzo (USA)Stefano Del Prato (Italy)James B. Meigs (USA)John S. Yudkin (UK)

Scientific SecretariatEndocrinology, Diabetes and MetabolismUniversity and Hospital Trust of VeronaPiazzale Stefani, 1 - 37126 Verona, ItalyTel +39 045 8123110 / Fax +39 045 8027314E-mail: enzo.bonora@univr.it

Organizing SecretariatCOGEST M. & C. Vicolo San Silvestro, 6 - 37122 Verona, ItalyTel +39 045 597940 / Fax +39 045 597265E-mail: cogest@cogest.info - www.cogest.info

Meeting VenueTeatro Scientifico Accademico del BibienaVia dell’Accademia, 47 - Mantova, Italy

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Wednesday, October 19, 2016

14.00 Registration

15.00 Opening Remarks Enzo Bonora (Italy)

SESSION I Chairman: Francesco Giorgino (Italy)

15.30 Brain and metabolic control Bernard Thorens (Switzerland)

16.15 Hormones from non endocrine organs and glucose homeostasis Michael Stumvoll (Germany)

17.00 Coffee break

SESSION II Chairman: Francesco Giorgino (Italy)

17.30 The contribution of gut microbioma Patrice Cani (Belgium)

18.15 Endocrine disruptors in food, drinks and air: environment plays a role Miquel Porta (Spain)

SCIENTIFIC PROGRAMME

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Thursday, October 20, 2016

SESSION III Chairman: Riccardo C. Bonadonna (Italy)

9.00 True origin of type 1 diabetes: opportunities for an effective prevention Paolo Pozzilli (Italy)

9.45 Pathogenesis of type 2 diabetes: octet or more? Ralph A. DeFronzo (USA)

10.30 Coffee break

SESSION IV Chairman: Riccardo C. Bonadonna (Italy)

11.00 Pharmacogenetics for targeted pharmacotherapy in type 2 diabetes Jose C. Florez (USA)

11.45 Human genetics to identify off target effects of diabetes therapies James B. Meigs (USA)

12.30 Lunch

13.30 SPONSORED SYMPOSIUM (non-CME certified)

14.30 FROM GLYCAEMIC VALUES TO RESPONSIBLE DIABETES MANAGEMENT

Chairman: Joerg Weissmann (Germany)

Optimizing therapy with technologies: a different point of view Francesco Giorgino (Italy) Is today diabetes management sustainable? Bernhard Kulzer (Germany)

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Thursday, October 20, 2016

SESSION V Chairman: Angelo Avogaro (Italy)

14.30 Drugs for obesity: just a dream? Luc Van Gaal (Belgium)

15.15 Beyond statins to prevent CVD in diabetes Alberto Zambon (Italy)

16.00 Coffee break

SESSION VI Chairman: Angelo Avogaro (Italy)

16.30 New horizons in SMBG, FGM and CGM Tadej Battelino (Slovenia)

17.15 Telemedicine for a comprehensive shared management Antonio Nicolucci (Italy)

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Friday, October 21, 2016 SESSION VII Chairman: Giorgio Sesti (Italy)

9.00 Back to the future: metformin, suphonylureas and glitazones Andrea Giaccari (Italy)

9.45 Pleiotropic effects of SGLT-2 inhibitors Anna Solini (Italy)

10.30 Coffee break

SESSION VIII Chairman: Giorgio Sesti (Italy)

11.00 True molecular mechanisms of DPP-4 inhibitors Angelo Avogaro (Italy)

11.45 The spectrum of GLP-1 receptor agonists Francesco Giorgino (Italy)

12.30 Lunch

SESSION IX Chairman: Stefano Del Prato (Italy)

14.30 Dual injective treatment is better than one Riccardo C. Bonadonna (Italy)

15.15 New insulins for old and new patients Giorgio Sesti (Italy)

16.00 Coffee break

SESSION X Chairman: Stefano Del Prato (Italy)

16.30 Hypertechnological insulin pumps John C. Pickup (UK)

17.15 Artificial pancreas Daniela Bruttomesso (Italy)

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Saturday, October 22, 2016 SESSION XI Chairman: Paolo Pozzilli (Italy)

9.00 Beta-cell replacement Lorenzo Piemonti (Italy)

9.45 Stem cells for restoring functional beta cell mass in diabetes Daniel Pipeleers (Belgium)

10.30 Coffee break

SESSION XII Chairman: Paolo Pozzilli (Italy)

11.00 Drugs to be Stefano Del Prato (Italy)

11.45 Will best practice in diabetes care be affordable in the future? John S. Yudkin (UK)

12.30 Closing remarks Enzo Bonora (Italy)

13.00 Farewell Lunch

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PARTICIPATIONOnly 200 attendees will be admitted to participate in the Workshop on a “first come, first served” basis.

REGISTRATION FEE

Senior (age ≥ 35 years) € 500,00 Junior (age < 35 years) € 250,00 The registration fee (VAT 22% included) covers:admission to scientific sessions, Workshop kit, certificate of attendance, lunches and coffee breaks (as indicated in the programme), social events (to be defined).

HOW TO REGISTER AT THE WORKSHOPIn order to register at the Workshop, participants are kindly requested to fill in the attached Registration Form.After filling in it, the form should be sent by fax to the Organizing Secretariat COGEST M. & C. (fax 0039 045 597265) or by e-mail (cogest@cogest.info) together with the payment of the fee, according to the instructions indicated below. The Organizing Secretariat will send an official receipt of the payment and further information about the Workshop.

ONLY FOR ITALIAN PARTICIPANTSReserved to Health Personnel working in Italian Public Administrations (Hospitals, Universities, Municipalities etc…)To receive an electronic invoice issued by a Public Administration with the SPLIT PAYMENT method (charging VAT to the public administration) or with VAT EXEMPTION (see art. 10 DPR 633/72 as modified by the art. 14 Law 24/12/1993 n. 537) you are kindly requested to provide compulsory the following information:· Specific request with the fiscal data of the Public Administration and Administration office

contact person (phone and e-mail)· Declaration in writing with all fiscal data of the Public institution where specified that the

employee (name and surname to be indicated) is authorized to attend the event for professional education purpose

· PA code (identifying the Public Administration) - it is a code composed by 6 alphanumeric characters

· Any other information that could facilitate the identification of the payment according to the e-invoicing rules

Once the invoice is issued any change involving a credit note or a new invoice with different heading will be charged € 30,00 + 22% VAT. If the organization does not pay by the beginning of the Workshop, payment has to be made by the participant, who will receive an invoice addressed to the institution.Registration fee can be paid by:- bank transfer in favour of COGEST M&C (a/c n. 000005233961, CIN H, ABI 02008, CAB 11705,

IBAN IT49H0200811705000005233961, BIC SWIFT UNCRITM1M03; UNICREDIT BANCA agency Piazza Bra 26/a, Verona, Italy), specifying the title of the event and the surname of the person for whom the payment is made; copy of the bank receipt must be mailed with the form;

- online payment http://www.cogest.info/congressi/pagamento.php (only for UNICREDIT Account holders and for payments with VISA or MASTERCARD credit cards);

- credit card, filling in the appropriate box in the form (AMERICAN EXPRESS, DINERS). Other forms of payment will not be accepted (postal order, cash, etc.).

GENERAL INFORMATION

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HOTEL ACCOMMODATIONAttendees can be accommodated in hotels located in Mantua at the following special rates (breakfast and VAT included; city tax not included, if requested from the hotel) which are valid until August 20th 2016 (maximum rate):Hotel Double Room Double as Single 4 stars € 160,00 € 130,00 3 stars € 143,00 € 110,00

HOW TO MAKE HOTEL RESERVATION In order to make hotel reservation, participants are kindly requested to fill in the attached Reservation form. The form should be sent by fax to the Organizing Secretariat COGEST M. & C. (fax 0039 045 597265) or by e-mail (cogest@cogest.info). Attendees are kindly requested to send the Reservation Form prior to August 20th 2016; reservation received after this date might not be accepted. Participants will receive a booking confirmation including name and address of the assigned hotel. In order to secure the reservation, the hotel requires a credit card number as guarantee. The card will be charged by the hotel at the time of check-out. The hotel accommodation charge will be invoiced directly by the hotel. A booking fee of € 13,00 will be charged to the credit card and invoiced by COGEST M. & C. BUSINESS & TRAVEL.

CANCELLATION POLICYRegistrationIn case of cancellation by September 21st 2016, 50% of the amount paid will be refunded.In case of cancellation after September 21st 2016, there will be no refund.HotelIn case of cancellation by August 20th 2016, only booking fee will be held.In case of cancellation from August 21st 2016 to August 31st 2016, booking fee and the charge for one night stay will be held.In case of cancellation from September 1st 2016 and in case of no show, the hotel will charge all nights stay on the credit card.

OFFICIAL LANGUAGEThe Workshop will be run in English.

ECM - CME (Continuing Medical Education) - Only for Italian participantsPROVIDER: COGEST M. & C. - COD. 979CME accreditation will be requested to AGENAS for a maximum of 200 medical doctors (specialties: Metabolic Diseases and Diabetology, Endocrinology, Internal Medicine, Geriatrics).

WEATHERThe weather in Mantua in October has an average temperature of 10°/ 20°C.

HOW TO REACH MANTUA (MANTOVA)By air: Verona “Valerio Catullo” Airport, 25 km from Mantua. The airport is well connected by daily flights with Rome, Paris, London, Frankfurt, Munich,

Amsterdam. A public shuttle service is provided by A.P.T. buses (AEROBUS leaving the Airport to the Railway Station “Verona Porta Nuova”. The service runs every 20 minutes and the trip is about 25 minutes long. Verona is connected with Mantua by regional trains (about 45 minutes trip).

By car: Highway A22 (Brennero-Modena), exit Mantua Nord (5 km from the city centre), two hours driving from Milan or Venice (A4 and then A22).

By train: Mantua Railway Station (1 km from the congress venue), two-hour trip from Milan.

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ENDORSEMENT

Regione Lombardia

Provincia di Mantova

Comune di Mantova

Università degli Studi di Verona

Azienda Ospedaliera Universitaria Integrata - Verona

Associazione Medici Diabetologi

Società Italiana di Diabetologia

Società Italiana di Endocrinologia

www.cogest.info/pdf/mantuadiabetesmellitus2016.pdf

1. Delegate InformationREGISTRATION FORM (part 1)

Address for correspondence

Name Job Title

Fax E-mail

Telephone Mobile Tel.

Surname Title (Prof/Dr/Mr/Mrs/Ms):

Information pertaining to Art. 13 of Legislative Decree 196 / 2003.The personal data will be treated for the purposes of secretarial operations concerning registration for the Workshop and for related services. In this respect, the rights ratified by the Art. 7 of legislative decree 196 / 2003 are guaranteed. Your data will be absolutely not disclosed to any commercial company. Responsible for the data’s treatment is Cogest M. & C. Ltd. – Vic. S. Silvestro n. 6, 37122 Verona (Italy); owner of the treatment is COGEST M. & C.

PRIVACY c Compliance with Italian Legislative Decree 196/2003 on privacy. The data will not be spread or communicated to people or organisations other

than the ones competent for the performance of the requested services. Your authorization for the use of your data is compulsory, without it we will not be able to proceed with the registration operations.

Date ___________________ Signature _______________________________________________________________________c I authorize the use of my registration data for the mailing of informative material by COGEST M. & C. / COGEST M. & C. declares that the data

will not be transmitted to third parties. Date ___________________ Signature _______________________________________________________________________

2. Heading of the invoice for registration fee (required)

Address

E-mail

Institution/Company - Name / Surname

V.A.T. Number Tax Code

4. Payment Information

3. Delegate Registration fees (All prices are in Euros)

Senior (age ≥ 35 years) c e 500,00 (= e 409,84 + 22% V.A.T.)

Junior (age < 35 years) c e 250,00 (= e 204,92 + 22% V.A.T.)

Registration fees include: admission to scientific sessions, Workshop kit, certificate of attendance, lunches and coffee breaks (as indicated in the programme), social events (to be defined).

Information about V.A.T. (Value Added Tax) for invoicing procedures (please read carefully the following information)

c UE private citizens V.A.T. or tax identification NUMBER (required)

For EXTRA UE Institutions or companies V.A.T. is not required. Please be informed that:· UE or EXTRA UE Institutions or Companies are due to pay registration fee V.A.T. excluded; · UE or EXTRA UE private citizens are due to pay registration fee V.A.T. included

c UE Institutions or Companies V.A.T. NUMBER (required)

City CountryProvinceZip Code

Only for Italian participants (CME credits information)CME accreditation will be requested to AGENAS for a maximum of 200 Medical Doctors (specialties: Metabolic Diseases and Diabetology, Endocrinology, Internal Medicine, Geriatrics).

c Medical Doctors specialties: c Metabolic Diseases and Diabetology c Endocrinology c Internal Medicine c Geriatrics

Date and place of birth _________________________ Tax Code - Cod. Fiscale (required)

Payment by Credit Card c Only for Visa and Mastercard Users online payment through COGEST M. & C. web site: following the instructions at: http://www.cogest.info/congressi/pagamento.php c Only for American Express and Diners Users payment with Credit Card: you are kindly requested to fill in this registration form, to sign it and send it by fax to

0039 045 597265. COGEST M. & C. will send you an official receipt for the payment and further organizing information.

Credit card: c AMERICAN EXPRESS c DINERS Expiration Date /

No.

Cardholder’s Name and Surname ______________________________________________________________

Payment by Bank Transfer c Bank transfer in favour of COGEST M. & C. srl, IBAN IT49H0200811705000005233961, BIC SWIFT UNCRITM1M03, on UNICREDIT BANCA, Piazza Bra 26/e, Verona (Italy)

specifying the title of the event and the Surname of the person you are making the payment for. Copy of the bank receipt must be faxed (+39 045 597265) or mailed (cogest@cogest@info) with the form.

Online payment by Bank Transfer only for UNICREDIT Account holdersc http://www.cogest.info/congressi/pagamento.php

6th Mantua WORKSHOP on DIABETES MELLITUS and Related Disordersthe future of diabetes care

Mantova (Italy) - Teatro Scientifico Accademico del Bibiena - October 19-22, 2016

Only for Italian participants: to receive an electronic invoice issued by a Public Administration see the program at page 8 or part 2 of this registration form

City CountryProvinceZip Code

c I authorize Cogest M. & C. BUSINESS & TRAVEL to charge my credit card with the Workshop registration fee e ____________

Signature __________________________________________________________ Date

Special dietary requirement or food intolerance

REGISTRATION FORM (part 2)

Name

Surname

Date of arrival

Date of departure

Cardholder’s name

Cancellation Policy· In case of cancellation by August 20th 2016, only booking fee will be held.

· In case of cancellation from August 21st 2016 to August 31st 2016, booking fee and the charge for one night stay will be held.

· In case of cancellation from September 1st 2016 and in case of no show,

the hotel will charge all nights stay on the credit card.

(the last 3 numbers on the back side of the credit card; the CVV is not requested if the credit card is AMERICAN EXPRESS or DINERS)

Surname/Namec Accompanying person

c AMERICAN EXPRESS c DINERS c VISA c MASTERCARD/EUROCARD

c Other participant in the Workshop

Estimated time of arrival

Estimated time of departure Number of nights

I wish to share the room with:

Expiration Date

CVV Code

No.

Please COMPLETE as guarantee for the hotel and for the payment of booking fees (€ 13,00):

5. Hotel Reservation details

Category 3 stars c n. ______ DOUBLE ROOM maximum rate e 143,00

Category 3 stars c n. ______ DOUBLE AS SINGLE ROOM maximum rate e 110,00

Category 4 stars c n. ______ DOUBLE ROOM maximum rate e 160,00

Category 4 stars c n. ______ DOUBLE AS SINGLE ROOM maximum rate e 130,00

Rates are intended per room, per night, breakfast and VAT included - The hotel accommodation charge will be invoiced directly by the hotel. (City tax, if required, not included).

To receive an electronic invoice issued by a Public Administration with the SPLIT PAYMENT method (charging VAT to the public administration) or with VAT EXEMPTION (see art. 10 DPR 633/72 as modified by the art. 14 Law 24/12/1993 n. 537) you are kindly requested to provide compulsory the following information:· Specific request with the fiscal data of the Public Administration and Administration

office contact person (phone and e-mail)· Declaration in writing with all fiscal data of the Public institution where specified

that the employee (name and surname to be indicated) is authorized to attend the event for professional education purpose

· PA code (identifying the Public Administration) - it is a code composed by 6 alphanumeric characters

· Any other information that could facilitate the identification of the payment according to the e-invoicing rules

RESERVED TO HEALTH PERSONNEL WORKING IN ITALIAN PUBLIC ADMINISTRATIONS (HOSPITALS, UNIVERSITIES, MUNICIPALITIES ETC…)

ONLY FOR ITALIAN PARTICIPANTS:

Information pertaining to Art. 13 of Legislative Decree 196 / 2003.The personal data will be treated for the purposes of secretarial operations concerning registration for the Workshop and for related services. In this respect, the rights ratified by the Art. 7 of legislative decree 196 / 2003 are guaranteed. Your data will be absolutely not disclosed to any commercial company. Responsible for the data’s treatment is Cogest M. & C. Ltd. – Vic. S. Silvestro n. 6, 37122 Verona (Italy); owner of the treatment is COGEST M. & C.

PRIVACY c Compliance with Italian Legislative Decree 196/2003 on privacy. The data will not be spread or communicated to people or organisations other

than the ones competent for the performance of the requested services. Your authorization for the use of your data is compulsory, without it we will not be able to proceed with the registration operations.

Date ___________________ Signature _______________________________________________________________________c I authorize the use of my registration data for the mailing of informative material by COGEST M. & C. / COGEST M. & C. declares that the data

will not be transmitted to third parties. Date ___________________ Signature _______________________________________________________________________

Signature __________________________________________________________ Date

c I authorize Cogest M. & C. BUSINESS & TRAVEL to charge my credit card with € 13,00 as booking fee and the hotel to charge the hotel rate according to the cancel-lation policy indicated in the programme.

6th Mantua WORKSHOP on DIABETES MELLITUS and Related Disordersthe future of diabetes care

Mantova (Italy) - Teatro Scientifico Accademico del Bibiena - October 19-22, 2016