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Page 1: A metalic di- or trivalent transition element An essential ...ocw.usu.ac.id/course/download/1110000100-basic-biology-of-cell-1/bbc... · A metalic di- or trivalent transition element
Page 2: A metalic di- or trivalent transition element An essential ...ocw.usu.ac.id/course/download/1110000100-basic-biology-of-cell-1/bbc... · A metalic di- or trivalent transition element

A metalic di- or trivalent transition element

An essential constituent of hemoglobin and myoglobin → store and transport oxygen

hemoglobin : red blood cell

myoglobin : muscle tissue

Part of various enzyme

Page 3: A metalic di- or trivalent transition element An essential ...ocw.usu.ac.id/course/download/1110000100-basic-biology-of-cell-1/bbc... · A metalic di- or trivalent transition element

• Essential cofactor of :• Oxygen transport• Respiration• Amino acid• Lipid• Alcohol• Vitamin A• Sulfite metabolism• Various other redox reaction

Page 4: A metalic di- or trivalent transition element An essential ...ocw.usu.ac.id/course/download/1110000100-basic-biology-of-cell-1/bbc... · A metalic di- or trivalent transition element
Page 5: A metalic di- or trivalent transition element An essential ...ocw.usu.ac.id/course/download/1110000100-basic-biology-of-cell-1/bbc... · A metalic di- or trivalent transition element
Page 6: A metalic di- or trivalent transition element An essential ...ocw.usu.ac.id/course/download/1110000100-basic-biology-of-cell-1/bbc... · A metalic di- or trivalent transition element
Page 7: A metalic di- or trivalent transition element An essential ...ocw.usu.ac.id/course/download/1110000100-basic-biology-of-cell-1/bbc... · A metalic di- or trivalent transition element

A metallic, divalent transition element

Essential for the activation of numerous genes

Vegetarian, pregnant or breastfeeding women need slightly more

The ‘Macho Mineral ‘the largest quantities of zink in the male human body in the testes ~ testosterone – to produce plentiful healthy, viable

sperm

Page 8: A metalic di- or trivalent transition element An essential ...ocw.usu.ac.id/course/download/1110000100-basic-biology-of-cell-1/bbc... · A metalic di- or trivalent transition element

F U N C T I O N :• Protect nerve and brain tissue• Bolsters the immune system• Essential for healthy growth• Part of enzymes and hormones (such as

insulin)

S O U R C E S :Oysters, other shellfish, eggs and meat

Page 9: A metalic di- or trivalent transition element An essential ...ocw.usu.ac.id/course/download/1110000100-basic-biology-of-cell-1/bbc... · A metalic di- or trivalent transition element
Page 10: A metalic di- or trivalent transition element An essential ...ocw.usu.ac.id/course/download/1110000100-basic-biology-of-cell-1/bbc... · A metalic di- or trivalent transition element

A transition metal

An antioxidant found in enzymes that deactivates free radicals

Assists the body to employ iron

Slowing the aging process by decreasing the incidence of protein glycation → bone loss, high cholesterol, cardiac abnormalities

-People with diabetic → loss of vision

Page 11: A metalic di- or trivalent transition element An essential ...ocw.usu.ac.id/course/download/1110000100-basic-biology-of-cell-1/bbc... · A metalic di- or trivalent transition element

Function

• Essential for energy metabolism (cellular respiration)

• Brain function (neurotransmitter regulation)• Soft tissue and bone (collagen synthesis)• Nutrient metabolism (especially iron)• For antioxidant defense against free radicals

Page 12: A metalic di- or trivalent transition element An essential ...ocw.usu.ac.id/course/download/1110000100-basic-biology-of-cell-1/bbc... · A metalic di- or trivalent transition element

In addition, copper :– promotes the growth of strong bones– promotes the health of nerve tissues– prevents your hair from turning gray

prematurely

Page 13: A metalic di- or trivalent transition element An essential ...ocw.usu.ac.id/course/download/1110000100-basic-biology-of-cell-1/bbc... · A metalic di- or trivalent transition element
Page 14: A metalic di- or trivalent transition element An essential ...ocw.usu.ac.id/course/download/1110000100-basic-biology-of-cell-1/bbc... · A metalic di- or trivalent transition element
Page 15: A metalic di- or trivalent transition element An essential ...ocw.usu.ac.id/course/download/1110000100-basic-biology-of-cell-1/bbc... · A metalic di- or trivalent transition element

A component of the thyroid hormones thyroxin and triiodothyronine

- help regulate cell activities

- essential for protein synthesis

- tissue growth (the formation of healthy nerves and bones)

- reproduction

Page 16: A metalic di- or trivalent transition element An essential ...ocw.usu.ac.id/course/download/1110000100-basic-biology-of-cell-1/bbc... · A metalic di- or trivalent transition element

Deficiency

• A lack of iodine cause :– Spontaneous abortion and birth defects– Impairs irreversibly brain and physical development in the fetus

and young children– Mild to severe mental retardation– Hearing loss– Paralysis leg

– Older children and adult → excessive growth of the thyroid gland (goiter), slows metabolic rate, mental and cardiac function and induces a feeling of fatigue and cold intolerance

Page 17: A metalic di- or trivalent transition element An essential ...ocw.usu.ac.id/course/download/1110000100-basic-biology-of-cell-1/bbc... · A metalic di- or trivalent transition element
Page 18: A metalic di- or trivalent transition element An essential ...ocw.usu.ac.id/course/download/1110000100-basic-biology-of-cell-1/bbc... · A metalic di- or trivalent transition element
Page 19: A metalic di- or trivalent transition element An essential ...ocw.usu.ac.id/course/download/1110000100-basic-biology-of-cell-1/bbc... · A metalic di- or trivalent transition element

A transition metal

Essential for several enzyme to metabolize fat

A necessary partner for Glucose Tolerance Factor (a group of chemical that enables insulin to regulate of glucose utilization)

Cr alone binds to nuclear DNA and increases the number of initiation sites for RNA synthesis

Sources :nut, whole grains, yeast and cheese

Page 20: A metalic di- or trivalent transition element An essential ...ocw.usu.ac.id/course/download/1110000100-basic-biology-of-cell-1/bbc... · A metalic di- or trivalent transition element

A transition metal with potential valences +2, +3 and +7

In glands (pituitary, mammary, pancreas), organs (liver, kidneys, intestines); and bones

Sources :

Whole grains, sweet potatoes, cereal products, fruit and vegetables(spinach), tea

Page 21: A metalic di- or trivalent transition element An essential ...ocw.usu.ac.id/course/download/1110000100-basic-biology-of-cell-1/bbc... · A metalic di- or trivalent transition element

FUNCTION

• An essential constituent of the enzymes thatmetabolize carbohydrates, protein digestion andmetabolism, synthesize fats (cholesterol), biotinfunction, cartilage regeneration and free radicaldefense

• Important for a healthy reproductive system• During pregnancy, manganese speeds the proper

growth of fetal tissue, particularly bones andcartilage

Page 22: A metalic di- or trivalent transition element An essential ...ocw.usu.ac.id/course/download/1110000100-basic-biology-of-cell-1/bbc... · A metalic di- or trivalent transition element

A transition element with valences 2,3,4,5 or 6

Humans need amount of Mo for metabolism protein, sulfite, nucleic acids, aldehydes and taurine

Have a role in function of glucocorticoid hormones and immune defense

Sources : beans, grains, leavy vegetables, milk and cheese

Page 23: A metalic di- or trivalent transition element An essential ...ocw.usu.ac.id/course/download/1110000100-basic-biology-of-cell-1/bbc... · A metalic di- or trivalent transition element
Page 24: A metalic di- or trivalent transition element An essential ...ocw.usu.ac.id/course/download/1110000100-basic-biology-of-cell-1/bbc... · A metalic di- or trivalent transition element

FUNCTION :

• A cofactor for enzymes and proteins with vital importance in :– Antioxidant defense– Thyroid hormones and insulin function– Regulation of cell growth– Maintenance of fertility

Page 25: A metalic di- or trivalent transition element An essential ...ocw.usu.ac.id/course/download/1110000100-basic-biology-of-cell-1/bbc... · A metalic di- or trivalent transition element

- A metallic transition element

- A part of vitamin B12

- Function : -An essential cofactor ~ regulation of translation- A constituent of an oxygen sensor

Page 26: A metalic di- or trivalent transition element An essential ...ocw.usu.ac.id/course/download/1110000100-basic-biology-of-cell-1/bbc... · A metalic di- or trivalent transition element

• A strict vegetarian : Fe, Ca (soybean milk fortified with Ca, orange juice with added Ca)

• Live inland, away from the ocean• A man and a woman• Pregnant and Breast Feeding (Ca, P, Mg,Fe, Zn and Selenium)

• Menopause

Page 27: A metalic di- or trivalent transition element An essential ...ocw.usu.ac.id/course/download/1110000100-basic-biology-of-cell-1/bbc... · A metalic di- or trivalent transition element