a clinical study on aya bringaraja karpam in veluppu noi

8/11/2019 A Clinical Study on Aya Bringaraja Karpam in Veluppu Noi

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M

S.Vol.XX, No. 1-2, (1999) pp. 83-88

t'VJJ

7*

' C M l C A L S T U D Y

tin Mi

BRINGARAJA

KARPAM IN

VELUPPU

NOI

m-

K. Ganapathiraman

1

, J. Annathai

2

and K. Sivaprakasam

3

(Received on 2-11-99)

clinical study on Ay a Bringaraja

im in the treatment ofVeluppu Noi

inducted in I.P.D. level. A total

Herof 321VeluppuNoi patients were

ted with the trial drug A y a Bringaraja

m at a dose of260mgs.three timesa

to evolveits therape utic efficacy.

Periodical assessment and routine

oratory investigations such as Hb ,

PCV, MC V, urine and motion

inations were also carriedout. It has

observed that the Ranjaka Pitham

pihala Pitham have been mainly

I in VeluppuNo i patients. The trial

|gives a significant effect in the

ition of Veluppu Noi (A condition

or less similar in the hypochronic

icrocyticanaemia).

IK; *

i p :

Introduction

Veluppu Noi (anaemia) is one among

tbe common d iseases, which predominently

seai in most of the people. Though the

VeluppuNoi (anaemia) is a symptom ofa

disease as per modern aspect, the ancient

Siddhars included it as a disease in their

texts. In which, explains that this disease

also occurs due to Karma and it is also

called asKarma Noi.

In this clinical study it has been

observed that the

Ranjaka Pitham

and

Anala Pitham have been mainly affected

due to extrinsic and intrinsic factors. A

total number of 321 cases in both sexes

were studied in I.P.D . level. In a sequential

study

Aya B ringaraja Karpam

was taken

upfo r the clinical trial to evolve the efficacy

of the drug in Veluppu Noi.

Materials and Methods

A total number of 321

Veluppu Noi

patients were studied in I.P.D. level. Both

male and female patients having

low

I. Research Officer

|L Asst. Rese arch Off icer

Assistant Director

begional Res earch Institute (Siddha ), Central Coun cil for Resea rch in Ayurveda and Siddha, G ovt.

barmacy (Ups) Indira Nagar, Pondicheny-6

83


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K. GANAPATHERAMAN, et al.

percentage of heamoglobin between 40%

and 60 % were admitted for the study,

laboratory findings were recorded before

and after treatment.

The patients were kept for observation

on the first day and they were given

Megana tha Mathirai was administred and

in the next day m orning with hot water a t

empty stomach according to the patient's

condition as a purgative. The patients who

were suffering from worms infestation were

given

Murukkan VithaiMathirai.

The trial drugAy a Bringaraja Karpam

260 mgs. was administred three times a

day with honey. During the course of

treatment patients werecarefullyexamined

and symptomatic treatment were also given.

Ordinary Indian diet was given containing

egg, meat, green vegetables and fruits.

Clinical progress was assesed by the

periodical laboratory investigation.

Results and observation :

In this clinical study it has been

observed that the various aspect such as

sex, age, Prakruthi, symptom wise

distribution, etc. The details of studies

given below in (Tables 1 to 7).

Table 1

Sex distribution in 321 cases of

Vellupu Noi

Sex

Number of patients

Male

Female

119

202

Table 2

Distribution of 321 case of VellupuNc

in different age groups 1

Age group

Number of

(age in years)

patients ^

10-20

-ii

106

21-30

63

31-40

53 1

i-i

41-50

56

51-60 42

60 andabove 1 J

Table 3

Classification of

Prakruthi

in 321 cases

of Vellupu Noi J

Prakruthi Num ber of

patient v

Valha Udal

Pitha Udal

Kaba Udal

Thontha Udal

80

102

78

41

{

4

Table 4

Duration of illness in 321

Vellupu Noi

case

i .w;

4

Duration

(in months)

Number of

patient

T

0 1

1-4

5-8

9-12

More than1 year

8

49

96

80

88

m

j j

iU


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CLINICAL ST UD Y Obi Y BRING R J KARPAM W V LUPPUNOI

3 * Table 5

wise classification of 321 cases

1

of VellupuNoi

Liii

Number of

patient

57

111

110

42

1

Table 6

W&M J..

if Duration of treatment in 321

V n ; Vellupu Noi cases

it,

Number of

cases

'{'I


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K. GANAPATHIRAMAN, et al.

improvement was noted in the patients.

The results are given at (Table-8).

Discussion

An attempt

has

been made in the present

study about the various aspects of the

Veluppu

Noi

from the view point of Siddha

concept. The trial drug

Ay a Bringaraja

Karpam has been taken up to evolve its

efficacy in the treatment ofVeluppuNoi,

which was prepared by IMPCO PS, Adayar-

Chennai, having the combination of herbs

and minerals. It w as also noticed, that there

were more number ofPitha Udalpatients,

in present study. The efficacy of the

treatment shows significantly well in

conformity with clinical observation of

signs and symptoms. Out of321patients

122 complete relief, 125 moderate relief,

11 mild relief and 63 patients had left

against medical advice. In this study the

mean haemoglobin valuewas48.7% before

treatment and 72.6% after treatment.

It was observed that more number of

patients had pallor of the skin due to

derangement of Pirasaka Pitham and

Ranjaka Pitham. These two factors are

mainly responsible for the colour of the

skin and

blood.

Since the

Ranjaka Pitham

is in the stomach it gives red colour to the

absorbed food material suchasRasaby the

intestine. Pirasaka and Ranjaka Pitham

have also been found affected in this

condition.

301

patients had loss of appetite due to

impairment of

Analapitham,

which, helps

in the digestion of food.

120 cases had dyspnoea on exerticjj

due to derangement of Pram V ^ f ^

oxygen. All the 131 patients had kg

number of red blood corpuscles who.ag

responsible to carry oxygen to van.

parts of the body. As the R .B.C . a re less

Veluppu Noipatients, the transportation

oxygen is considerably reduced which

inturn leads to dyspnoea.

On observation of SevenUdalDhathus

that a l l pat ien ts were subjected to

defficieney of

Rasa Dhathu

and

Raktha

Dhathu.

The deficiency of

RakthaDhathu

was found out through the signs pallorof

the skin, eye and nail beds. It was also

confirmed by the laboratory findings

t h

the all patients showed low percentage,

HB and RBC.

When the digestion is impaired,

is less possibility fo r the forma tion ofRasa

Dhathu. Rasa DhathuandRakthaDhathu

are the basic factors for the formation of

other Dhathu. The Raktha Dhathu takes

place a vital role in

Veluppu Noi.

Conclusion

In this study it is observed the

malnutrition is the main cau se f orVeluppn\

Noi. Poor socio economic conditions and

f-

excess bleeding during the menstrual cycle,

frequent delivery and worm in festationare,-

seen to be the m ain causative fac tors of his??

disease. The clinical study was made in-

various aspects with relevant factors. Thg

/S:

characteristic of

Raktha Dhathu

and

Rasa

Dhathu

aiid- its fo rm atio n hav e been


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[CLINICAL STUDY

ON Y BRING R J KARPAM I

N

VALUPPUNOI

plained in Siddha aspects. In this study

found that more female patients

|affected than males. The e fficacy of

i

treatment is well in conformity with the

ion of clinicalsignsand symptoms.

therapeutic value ofAya Bringaraja

irpamwas also assessed. T he results are

at (Table 8).

Acknowledgement

The authors are very grateful to the

Director, Central Council for Research in

Ayurveda and Siddha, New Delhi for his

encouragement & financial assistance.

Authors also thanks to Sh. V. R ajendran,

UDC and Sh. George Joseph, GDA for

their secretarial assistance.

REFERENCES

if

lyan, C. S.

h

r, Kuppu Samy &

lyan, C.S.

ludaliar, Kuppu Samy

rnga Velu, M.

Yugimuni

1975 Agasthiar Paripooranam400, P. 47 &

48, Rathina Nay ak K ar and Sons.

1953 SiddhaMaruthu Vanga Page 50 to 58

& 60 , Churukkam, G ovt. Press. Tamil

Nadu.

1966 Siddha VaidyaThiratha

3rd,

Edn., Page

234, Shunmuga Nande Book shop

1954 Siddha Maruthuvam, P. 263 & 269,

Govt. Press, Tam il Nadu.

1967 NoiNadal NoiMudalNadal, Part II, P.

201-202, Govt, press, Tamil Nadu.

1969

Yugimnivar Viadya Chinthamani

, P.

112 &. 114, B. Rathina Nayak Kar &

Sons.

87


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K. GANAPATHTRAMAN, et al.

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a clinical study on aya bringaraja karpam in veluppu noi

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