9 nutrtion of joints bones

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     Abazar Habibinia, MD, CSDTT, DFN

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    Structure of a Joint:

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    Joint pain results from:

    1) Damage to cartilage as in Osteoarthritis(OA). 

    Damage to synovial membrane as in Rheumatoid Arthritis (RA). 

    2) Decreased synovial Fluid. 

    3) Damage to meniscus (in knees only). 

    4) Injury to surrounding

    ligaments and tendons. 

    6) Deposition of uric acid.

     7) Referral pain.

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    The Joints Are Made of:

    Synovial Fluid:  Cartilage:1) Water

    2) Hyaluronic acid(Hyaluronan)

    1) Gylcosaminoglycans(GAG):

    Glucosamine

    Chondroitin Sulfate

    Dermatan Sulfate

    Keratan Sulfate 

    2) Collagen (Protein):

    Glycine 

    Lysine  Hydroxylysine Proline  Hydroxyproline 

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    Proper Nutrition and Supplementation:

    Reduce pain.

    Decrease inflammation.

    Improve flexibility. Help repair cartilage.

     Accelerate healing process.

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    Decreased Synovial Fluid: 

    Symptoms: Dietary Recommendations:

    Pain

     Joint stiffness Loss of joint flexibility

    Cracking or PoppingSound * 

    1) Drink plenty of water: more than 3liters a day

    2) Hyaluronic acid: 400 mg per day.

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    Cracking or Popping Sound: 

    Decreased synovial fluid

    Negative pressure within the joint

    Release of dissolved gases (mostly Co2)

    Formation of bubbles

    Cracking sound

    *This process is called “cavitation” within the joint. 

    ** No arthritis or other aliments comes from cracking.

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    Damage to Cartilage

    (Osteoarthritis; OA)

    Damage to Synovium

    (Rheumatoid Arthritis; RA)

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    Damage to Cartilage

    (Osteoarthritis; OA)

    Damage to Synovium

    (Rheumatoid Arthritis; RA)

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    Nutritional Advices in OA and RA:

     A) Dietary Recommendations:饮食1) Drink plenty of water.2) Eat more fiber.

    3) Eat more flaxseed and cold water fish (salmon, mackerel).

    4) Eat more of sulfur-rich foods: cabbage, asparagus, garlic, and onion.

    B) Foods to Avoid:

    1) Saturated fats, acidic foods, sugar, high gluten foods, alcohol, caffeine.

    2) Foods high in Omega-6 (sunf lower, corn, sesame, borage, evening prim roseoils).

    3) Foods high in “Solanine”: potatoes, tomatoes, eggplant, and peppers(except black pepper).

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    Foods High in Solanine:

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    Foods High in Solanine:

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    C) Food Supplements:

    Glucosamine: It is an important building block of cartilage.

    Sources:

    *Not exist in significant amount in foods.*Comes mainly as supplement:

    1) Derived from the shells of shrimps, lobster, and crabs.

    2) Made synthetically.

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    Indications of Glucosamine:

    1) Osteoarthritis:a) Reduces inflammation

    b) Relieves pain

    c) Helps repair cartilage

    d) Inhibits joint breakdown.

    2) Strain and Sprains.

    3) Wound healing.

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    Dosage of Glucosamine:

    It comes in two forms: sulfate, and hydrochloride.

    It must be taken 1500 – 2000 mg per day in single dose

    or divided doses for at least 6 weeks. Side Effects and Interactions:

    1) Stomach upset. 

    2) Diarrhea. 

    3) It might cause insulin-resistance, leading to increaseblood sugar. Diabetic people should consult theirdoctors. 

    4) If glucosamine has been stabilized in NaCl, it mightincrease blood pressure. 

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    5) People who have allergy to shrimps could takeglucosamine, as allergy is usually to a protein found in

    the meat part.6) Sulfur is an important part of Glucosamine. Advil andTylenol require sulfation in their metabolism and in factit has been shown to compromise glucosamine synthesis.

    No Glucosamine and Advil or Tylenolat the same time!

     

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    Interaction of Glucosamine with Advil and Tylenol:

     Advil and Tylenol need sulfur for their liver

    metabolism

    Sulfur

    Glucosamine needs sulfur to repair cartilage

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    Chondroitin Sulfate

    1) Naturally found in cartilage and tendons.

    2) Reduces pain and inflammation.

    3) Inhibits joint degradation (breakdown).

    4) Made from cow`s cartilage or shark `s cartilage. 5) The dosage is 1200 mg daily.

    6) Very high dose ( more than 10 grams) may causediarrhea.

    7) Some studies show that it might prevent from heartattack and also kidney stones of oxalate type.

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    Methylsulfonylmethane (MSM)

    1) Naturally found in the body and many foodsespecially green vegetables.

    2) It is a good source of mineral sulfur (sulfur donor).

    3) Reduces inflammation and pain.

    4) Used in combination with Glucosamine.

    5) The dosage is 250 to 500 mg daily.

    6) Has a mild blood-thinning effect.

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    Capsaicin

    Used in the treatment of joint pain and phantom pain. Active component of Chili pepper.Blocks the release of “Substance – P”. 

    Capsaicin 

    Release of Substance – P

    Stimulation of Pain Receptors

    Pain 

    Sensory Nerves

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    Damage to Menisci, Ligaments, and Tendons:

    Foods to Avoid:

    1) Foods high in “Solanine”: tomatoes, potatoes, eggplant, and bell peppers.

    2) Foods high in Omega-6 (sunflower, corn, sesame, borage, evening prim

    rose oils)

    Food Supplements to Suggest:

    1) Omega-3 (high dose reduces inflammation).

    2) OPC- 3 (speeds up healing process).

    3)  Vitamin C (speeds up healing process).

    4) Glucosamine (helps repair and reduces inflammation).5)  Arginine (increases blood flow to the area) in chronic cases.

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    Gout:  Is due to deposition of Uric Acid in the joint.

    Known as “disease of kings” or “rich man`s disease”. 

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    Nutritional Advices in Gout:

     What Do Nutritional Advices Do for People with Gout?

    1) Reduce production of uric acid.

    2) Increase excretion of uric acid from the body.

     3) Prevent from two long term consequences,osteoarthritis and kidney stones.

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    Nutritional Advices in Gout:

    Highly Recommended: Highly Restricted:

     Water, more than 3 liters a day.

    Berries, especially strawberries andblueberries.

    Flaxseed.

    Celery. Fish (salmon, cod, halibut).

    Lime.

    Lemon.

     Vinegar.

    Soy protein.Dairy products (low fat).

    Coffee.

    Beef, Pork, Chicken, Turkey. Fish (sardines, herring, mackerel,

    anchovies). Sweetbreads (animal thymus). Eggs. Beef kidneys. Liver. Brain. Scallops, Shrimps, Mussels. Meat broths and gravies. Beans (legumes). Spinach. Rhubarb. Mushroom.

     Asparagus. Cauliflower. Beer.  Alcohol. Refined sugars.

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    Food Supplementation in Gout:

    1) Omega -3 (reduces inflammation).

    2) OPC- 3 (reduces inflammation and uric acid level).

     3) Folic acid (reduces uric acid level).

    4)  Vitamin C (increases excretion of uric acid via urine).

    5) Nettle tea (increases excretion of uric acid via urine).

    6) Celery extract (reduces uric acid level and inflammation).

    7) Quercetin (reduces uric acid level).

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