4 hypertensive kids in 45 minutes. name: anthony age: 6 sex: male place: allergy clinic bp: 145/87
TRANSCRIPT
4 Hypertensive Kidsin 45 Minutes
Name: Anthony
Age: 6
Sex: Male
Place: Allergy Clinic
BP: 145/87
Name: Chris
Age: 17
Sex: Male
Place: Inpatient
BP: 180/115
Name: Brittiney
Age: 13
Sex: Female
Place: Clinic
BP: 125/78
Name: Caleb
Age: 3
Sex: Male
Place: Phone Call
BP: 118/75
Caleb
AnthonyBrittiney
Chris
The Fourth Task Force Report on Pediatric High Blood Pressure
6 Questions
• Does the child really have high blood pressure?
• Do I have time to ask any more questions?• Why does the child have high blood
pressure? • Does the child have other risk factors? • What has high blood pressure already
done to the child's body? • What should we do about it?
6 Questions
• Does the child really have high blood pressure?
• Do I have time to ask any more questions?• Why does the child have high blood
pressure? • Does the child have other risk factors? • What has high blood pressure already
done to the child's body? • What should we do about it?
Blood Pressure Measurement Technology is in the Dark Ages.
Confirm all blood pressure readings before acting.
It’s a Pain in the A** to Detect HTN
Equipment is inherently flawed, hard to findOr gives inaccurate readings if not used right.
It’s a Pain in the A** to Detect HTN
Spurious elevations are common
It’s a Pain in the A** to Detect HTN
Not everyone has a BP reading.
It’s a Pain in the A** to Detect HTN
Mild Hypertension takes weeks to confirm
It’s a Pain in the A** to Detect HTN
Norms for Pediatric BP are found in a 4-D table
It’s a Pain, But you Got to Do it
http://www.statcoder.com/growthcharts.htm
Normal
< 90% le
Pre-Hypertension
90-95% le
Stage 1 Hypertension95% to 5 mm above 99%le
Stage 2 Hypertension> 5 mm above 99%le
Hypertension is Common
02468
101214161820
Hypertension Asthma
%
Caleb118/75
Anthony145/87
Brittiney125/78
Chris180/115
161 cm (72%le)
95% BP = 126/8290% BP = 122/78
114 cm (75%le)
168 cm (16%le)
98 cm (64%le)
95% BP = 113/7499% BP = 120/82
95% BP = 133/8599% BP = 141/93
95% BP = 110/6799% BP = 118/75
Recognizing or ruling out a hypertensive emergency is the 1st
order of business in any hypertension evaluation.
6 Questions
• Does the child really have high blood pressure?
• Do I have time to ask any more questions?• Why does the child have high blood
pressure? • Does the child have other risk factors? • What has high blood pressure already
done to the child's body? • What should we do about it?
Is this an Emergency?
Hypertensive Emergency
Elevated Blood Pressure with symptoms of end-organ damage
Hypertensive Urgency
A high BP that makes you uncomfortable
Hypertensive Emergencies
• Drop the Blood Pressure no more than 10%
• Use short acting IV medications– IV Labetolol– IV Hydralazine– IV Nicardipine drip
• Start small and then escalate your dose
• Get the patient to a PICU
Chris
Chest Pain and a splitting headache
Labetolol and hydralazine given on the floor – no effect. Nicardipine drip in PICU. BP 150s/80s by noon.
6 Questions
• Does the child really have high blood pressure?
• Do I have time to ask any more questions?• Why does the child have high blood
pressure? • Does the child have other risk factors? • What has high blood pressure already
done to the child's body? • What should we do about it?
School Age Teenager
Chronic UTIs
GlomerularDisease
RenovascularDisease
Aortic Coarctation
Essential Hypertension
Essential Hypertension
GlomerularDisease
RenovascularDisease
Other Causes of Pediatric Hypertension that you still think about• Inpatients
– Increased ICP– Pain– Iatrogenic steroid-induced
• Uncommon outpatient causes– Endocrine causes (Cushing, Pheo)– Pre-eclampsia
The Younger the Patient with Hypertension,
the More Likely you’ll find a Cause
Rule of Thumb #1
The Higher the Blood Pressure,
the more likely there’s a cause
Rule of Thumb #2
Symptoms to Ask About
History
UAC as a newborn
UTIs or febrile illnesses
Medications
Supplements
Family History
Physical
Arm & Leg BPs
A
B
C
What’s Normal?
1. A = B = C
2. A = B > C
3. A = B < C
4. A > B > C
What’s Normal?
1. A = B = C
2. A = B > C
3. A = B < C
4. A > B > C
Eye Grounds
Heart Findings
Listen for a Bruit
Skin
CALMs of NF-1Acanthosis Nigricans
Skin
Labs & Imaging
Pre-Hypertension
Lipids Fasting Glucose Echocardiogram Retinal Exam
Young Stage 1 or Stage 2
Renin CatecholaminesAngiogram Urine Steroids
+
Teenager Stage 1
RFP Urinalysis Renal Ultrasound+
Pre-Hypertension
Lipids Fasting Glucose Echocardiogram Retinal Exam
LVH on an echocardiogram is the most common end-organ manifestation in pediatric hypertension
Essential hypertension almost always occurs with other risk factors
Teenager Stage 1
RFP Urinalysis Renal Ultrasound
Quantitate any abnormal urine protein
There’s no normal creatinine in pediatrics, but there is a normal GFR.
Renal vessel doppler are of questionable value.
Young Stage 1 or Stage 2
Renin CatecholaminesAngiogram Urine Steroids
Plasma renin is usually uninterpretable.
Elevated urine catecholamines are usually transient and not subtle.
Don’t bother with MRAs or nuclear scans; the gold standard is an angiogram.
Caleb
Category of HTN: Young Stage 1History & Symptoms: NonePhysical: NormalLabs: NormalImaging:
Echo: Mild LVHU/S: Left kidney < RightAngio: Normal
Brittiney
Category of HTN: Pre-HypertensionHistory & Symptoms: SnoresPhysical: Elevated BMI ~ 98%le
Labs: Fasting BG 121Imaging:
Echo: NormalU/S: Normal
Life-style changes
Give a TV target of 2 hours per day or less
Write a prescription for PE
DASH diet (http://www.nhlbi.nih.gov/)
Surveillance
Lipids, Blood Sugars, Weight, Urine Protein
Ambulatory Blood Pressure Monitor (ABPM)
Ambulatory Blood Pressure Monitor
Anthony
Category of HTN: Young Stage 2History & Symptoms: Intermittent headaches
Physical: Single Café au LaitLabs: NormalImaging:
Echo: Moderate LVHU/S: NormalAngio:
Chris
Category of HTN: Teenager Stage 2History & Symptoms: Transplant;
On a dripPhysical: TachycardicLabs: Creatinine 1.7Imaging:
U/S:
Chris
Hydronephrosis, Ureteral obstruction
Blood pressure dramatically better (off drips) after nephrostomy
6 Questions
• Does the child really have high blood pressure?
• Do I have time to ask any more questions?• Why does the child have high blood
pressure? • Does the child have other risk factors? • What has high blood pressure already
done to the child's body? • What should we do about it?
7 Classes of Anti-hypertensives
• Diuretics• Beta-blockers IV labetolol• Central Alpha-Blockers• Calcium Channel Blockers nicardipine
drip• ACE Inhibitors• Direct Vasodilators IV hydralazine• Angiotensin Receptor Blockers• Peripheral Blockers
Take Home Points
• Report the percentile of Blood Pressure on Any BP you get
• Recognize a hypertensive emergency
• Refer to the 4th Task Force Report or your local pediatric nephrologist once you recognize a high blood pressure