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also from the back surface of the retina with a diffuse and a

punctuate characteristic of autofluorescence [8]. OCT shows

hyper intense granules caused by the occurrence of brush

border appearance in the area which fits with the outer

segments of photoreceptors and outer segments which were

widely scattered in subretinal space and over RPE due to the

prolonged serous detachment especially after 6wk[9-11].

In our study, our aim was to discuss and compare the fundus

FAF and OCT findings of acute or chronic CSCR cases.

SUBJECTS AND METHODS

Medical records of 40 acute and 60 chronic CSCR cases that

had been diagnosed between June 2010 and October 2011 in

Retina Department of Ulucanlar Eye Research Hospital, were

reviewed. CSCR had been diagnosed on the basis of clinical

findings, color fundus photography, fluorescein angiography

(FA) leakage pattern and OCT. All study procedures were

conducted in accordance with the Declaration of Helsinki,and informed consent was obtained from all the participants.

Our presentation was approved by Ethics Committee of

Ankara University, school of medicine.

All of the cases had a complete ophthalmological

examination. Also their color fundus photography, FAF

(488 nm) with Heidelberg Retina Angiograph 2 (HRA 2 ,

Heidelberg engineering, Germany), FA (KOVA imaging

systems, Japan) and spectral-domain OCT (SD-OCT)

(Heidelberg Engineering, Heidelberg, Germany) findings in

the initial and follow-up visits were also reviewed.

Cases were divided into acute and chronic-recurrent CSCR

according to the duration of decreased visual acuity (VA),

clinical findings of CSCR and focal leakage on FA. Acute

cases were defined as: duration of decreased VA, clinical

findings (ophthalmoscopically visible neurosensory

detachment) and FA findings (focal leakage)

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Figure 1 Images of a case with acute CSCR A: Color fundus photography of an acute CSCR 37-year-old male case shows serous

detachment; B,C: FA of the same case shows hyper-fluorescence at the leakage site which begins at the 35th second and increases in late

phases; D: Horizontal section of OCT of the same case shows serous detachment with distinct border but without any changes in the outer

segments of photoreceptors and serous fluid; E: Fundus autofluorescence photography reveals hypo-autofluorescence in the serous

detachment area with distinct borders and also hypo-autofluorescence at the leakage site in FA surrounded by iso-autofluorescence area of

normal retina.

Figure 2 Images of a case with chronic CSCR A: Color fundus photography of a 45-year-old chronic CSCR case shows yellowish-white

precipitates in macular area and RPE atrophy; B: The late phases of FA of the same case shows patchy hyper-fluorescence due to diffuse

leakage just above fovea and a window defect due to RPE atrophy at the leakage site; C: Horizontal section of OCT shows resorbed serous

detachment and precipitations over RPE; D: FAF photography shows scattered hyper-autofluorescence in the area of resorbed serous

detachment.

autofluorescence in FAF (Figure 2D). Figure 2C shows

horizontal section of macular OCT and it is difficult to say

that it shows resorbed serous detachment definitely. But a

shallow serous detachment under fovea and some

irregularities of RPE and atrophic regions can be seen but not

so clearly. Shallow serous detachment associated with CSCR

FAF and OCT in central serous chorioretinopathy

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mottled hyper-autofluorescence in 36% of their cases after

resorbtion of RD like in 37.5% of our cases (Figure 2D).

OCT is also a useful diagnostic tool in CSCR. Matsumoto[22] demonstrated the elongation of outer segments of

photoreceptors and narrowing of the outer nuclear layer in

OCT. In Kon [10] study, OCT showed, yellow hyper

reflective subretinal and intraretinal precipitations not only in

the posterior of RD but also within the RD. Dinc [17]

demonstrated hyper reflective foci in OCT which were

associated with hyperautofluorescent regions in FAF

photography. In our study, we also observed hyper reflective

foci in acute and chronic CSCR both in serous detachment

area and posterior of RD in OCT which was in accordance

with hyperautofluorescent regions in FAF.

This report emphasizes the importance of OCT and FAF

findings in addition to clinical ophthalmic examination not

only in the diagnosis but also in discrimination of differentstages of CSCR. As some changes occur in the leakage point

of RPE and serous RD area in time, acute and chronic CSCR

cases show different clinical and imaging characteristics. At

that point, the results of FA, FAF and OCT support and

complement each other and they can help the clinicians not

only in diagnosis and follow-up but also in planning their

cases treatments perfectly.

ACKNOWLEDGEMENTS

Conflicts of Interest: Teke MY,None; Elgin U, None;

Nalcacioglu-Yuksekkaya P,None;Sen E,None; Ozdal P,

None;Ozturk F,None.

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