19th iof advanced training course on osteoporosis · 3 08h00 - 08h40 registration 08h40 - 08h45...

Hôtel Lyon Métropole

February 2-4, 2010

Lyon, France

www.iofbonehealth.org/ltc2010

19th IOF Advanced Training Course on Osteoporosis

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• Lectures are 20 to 30 minutes, followed by 10 to 15 minutes of discussion.• Roundtable sessions address oral and written questions from the audience.• Meet-the-Professor sessions are informal discussions between small groups of

participants and a faculty member over lunch.

Teaching Faculty

S. BOONENDivision of Geriatric Medicine & Centre for Metabolic Bone DiseasesUniversity Hospitals LeuvenLeuven, BE

E.V. McCLOSKEYWHO Collaborating Centre for Metabolic Bone DiseasesUniversity of SheffieldSheffield, UK

M.L. BOUXSEINDepartment of Orthopedic SurgeryHarvard Medical SchoolBoston, US

M.R. McCLUNGOregon Osteoporosis CentrePortland, US

C. COOPERMRC Epidemiology Resource CentreUniversity of SouthamptonSouthampton, UK

S.E. PAPAPOULOSDepartment of Endocrinology & Metabolic DiseasesLeiden University Medical CentreLeiden, NL

W.H. DEREAmgen Inc.Uxbridge, UK

J.Y. REGINSTERDepartment of Public Health, Epidemiology & Health EconomicsUniversity of LiègeLiège, BE

J.A. KANISWHO Collaborating Centre for Metabolic Bone DiseasesUniversity of SheffieldSheffield, UK

R. RIZZOLIDivision of Bone DiseasesDepartment of Rehabilitation & Geriatrics Geneva University HospitalsGeneva, CH


February 2-4, 2010Hôtel Lyon Métropole • Lyon, France Course Leader Socrates E. Papapoulos

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08h00 - 08h40 Registration

08h40 - 08h45 Opening remarks S.E. Papapoulos

08h45 - 10h45 Discussion leader J.A. Kanis

08h45 - 09h30 Bone structure, function and strength M.L. Bouxsein

▪ organization and composition of bone▪ bone modeling and remodeling▪ bone cells▪ overview of histomorphometry▪ determinants of bone strength

09h30 - 10h15 Pathophysiology of bone loss R. Rizzoli

▪ bone growth and bone loss▪ changes in microarchitecture▪ molecular mechanisms▪ hormonal regulation▪ nutritional influence▪ roles of cytokines

10h15 - 10h45 Definition, epidemiology and social aspects of osteoporosis J.A. Kanis

▪ the clinical picture of patients with osteoporotic fractures▪ pattern of fracture incidence with age and sex▪ morbidity and mortality related to fractures

10h45 - 11h15 Coffee break

11h15 - 12.45 Discussion leader M.L. Bouxsein

11h15 - 11h45 Measurement of bone mass by DXA R. Rizzoli

▪ precision and accuracy, technical issues▪ lumbar spine, hip: which site to measure for which patient for

diagnosis and monitoring▪ total body bone mineral and soft tissue measurement: assessment of

fat and lean body mass, application to clinical trials

11h45 - 12h15 Biochemical markers of bone turnover M.R. McClung

▪ markers of formation and resorption▪ advantages and limitations of markers▪ technical and practical aspects of assays▪ markers in phase I to phase III trials of anti-osteoporotic agents▪ role of markers in the management of the osteoporosis patient▪ markers of bone quality

12h15 - 12h45 New imaging techniques for assessing bone quality and strength M.L. Bouxsein

▪ QCT▪ high resolution MRI and pQCT to assess microarchitecture▪ finite-element analysis▪ use in clinical practice▪ use in clinical trials

12h45 - 14h00 LunchMeet-the-Professor

14h00 - 15h30 Discussion leader M.R. McClung

14h00 - 14h30 What is an osteoporotic fracture? C. Cooper

▪ high/low energy fractures▪ relationship to BMD and gradients of risk▪ vertebral deformities: what is normal and abnormal?▪ which technique of vertebral morphometry to use for clinical trials in

osteoporosis?▪ clinical relevance of vertebral deformities▪ underdiagnosis of vertebral deformities▪ role of DXA

Tuesday February 2, 2010

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14h30 - 15h00 Assessment of fracture risk J.A. Kanis

▪ validity of risk factors▪ meta-analysis of risk factors▪ fracture probability

15h00 - 15h30 Biomechanics of age-related fractures M.L. Bouxsein

▪ interaction between skeletal loading and fracture etiology▪ implications for fracture prevention strategies

15h30 - 16h00 Roundtable Diagnostic tools and strategies for osteoporosis J.A. Kanis chairmanM.L. BouxseinR. Rizzoli


16h30 - 18h00 Discussion leader E.V. McCloskey

16h30 - 17h00 Nonpharmacological management of osteoporosis R. Rizzoli

▪ exercise▪ nutrition▪ rehabilitation▪ prevention of falls▪ kyphoplasty/vertebroplasty▪ specific measures in the elderly

17h00 - 17h30 Osteoporosis in men M.R. McClung

▪ fracture incidence in males▪ pathogenesis▪ diagnosis threshold for BMD▪ treatment

17h30 - 18h00 Corticosteroid-induced osteoporosis S. Boonen

▪ effect of corticosteroids on bone, intestine and kidney▪ epidemiology of corticosteroid-induced fractures▪ prevention and treatment: what really works?▪ recommendations to prevent corticosteroid-induced fractures

08h30 - 10h00 Discussion leader C. Cooper

08h30 - 08h45 What is the International Osteoporosis Foundation? P. McKenney

08h45 - 09h15 Calcium, vitamin D and its metabolites in osteoporosis S. Boonen

▪ calcium and vitamin D insufficiency as key determinants of fracture risk▪ calcium and fracture risk▪ definition, epidemiology and consequences of vitamin D deficiency▪ which vitamin D and how much to take?▪ the role of vitamin D supplementation in the elderly▪ clinical trials of vitamin D derivatives in osteoporosis: a critical review

09h15 - 10h00 Anabolic bone agents J.Y. Reginster

▪ the role of PTH in the treatment of osteoporosis: effects on bone mass (trabecular and cortical bone), bone turnover and fractures

▪ the role of strontium ranelate in the treatment of osteoporosis: ef-fects on bone mass (trabecular and cortical bone), bone turnover and fractures

10h00 - 10h30 Roundtable What is the role of general health program (including exercise) and of intervention on a peak bone mass for the prevention of osteoporosis?

R. Rizzoli chairmanM.R. McClungS. Boonen


Wednesday February 3, 2010

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11h00 - 12.45 Discussion leader S.E. Papapoulos

11h00 - 11h30 Hormone replacement therapy C. Cooper

▪ which oestrogen and progestin to use? ▪ effects on bone mass and fractures▪ nonskeletal effects (coronary heart disease, breast cancer, Alzheimers)

11h30 - 12h15 Clinical use of SERMs and other estrogen analogs E.V. McCloskey

▪ SERMs. concept of mechanism of action. effects on bone loss and fractures. effects on lipid metabolism and cardiovascular system. safety profile including breast and endometrium

▪ other oestrogen-like substances

12h15 - 12h45 Roundtable Hormonal intervention in osteoporosis C. Cooper chairmanJ.A. KanisE.V. McCloskey

12h45 - 14h15LunchMeet-the-Professor

14h15 - 15h45 Discussion leader R. Rizzoli

14h15 - 14h35 Bisphosphonates: pharmacology and safety S.E. Papapoulos

▪ pharmacology, pharmacokinetics, toxicology ▪ safety of bisphosphonates

14h35 - 15h15 Clinical use of bisphosphonates in postmenopausal osteoporosis E.V. McCloskey

▪ critical review of clinical trials ▪ efficacy on vertebral and nonvertebral fractures ▪ intermittent bisphosphonates

15h15 - 15h45 Other antiresorptive drugs and combined therapy J.Y. Reginster

▪ calcitonin▪ denosumab▪ combination/sequential therapy of antiresorptive and bone forming agents

15h45 - 16h15 Roundtable Non-hormonal intervention in osteoporosis S.E. Papapoulos chairmanE.V. McCloskeyJ.Y. Reginster


16h45 - 17h45 Discussion leader S. Boonen

16h45 - 17h15 Perspectives in the treatment of osteoporosis S.E. Papapoulos

▪ future antiresorptives▪ future anabolics

17h15 - 17h45 Tumoral bone disease E.V. McCloskey

▪ pathophysiology of bone metastases▪ pathogenesis of tumoral hypercalcemia of malignancy▪ role of adjuvant therapy with inhibitors of bone resorption

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08h30 - 09h30 Discussion leader W.H. Dere

08h30 - 09h00 Clinical guidelines for the diagnosis and treatment of osteoporosis J.A. Kanis

▪ diagnostic thresholds and strategies (WHO report)▪ therapeutic strategies▪ IOF vs. NOF guidelines▪ health economic implications

09h00 - 09h30 Design of intervention studies in osteoporosis S.E. Papapoulos

▪ which control group: placebo or reference treatment?▪ clinical criteria for selection of patients▪ choice of endpoints in preventive and curative treatment trials▪ sample size and power for comparing two or more treatments (type I,

II and III error)▪ good clinical practice

09h30 - 12h00 Discussion leader J.Y. Reginster

09h30 - 10h15 Health economics in the context of osteoporosis W.H. Dere

▪ the cost/benefit ratio of treatment▪ the economical impact of targeting intervention to patients with low

bone mass▪ economical evaluation of new drugs: methodology and endpoints


10h45 - 11h30 Registration of new drugs for osteoporosis

- FDA guidelines- CHMP guidelines

▪ registration requirements: which criteria for efficacy?▪ U.S. compared to European guidelines

W.H. DereJ.Y. Reginster

11h30 - 12h00 Development of a new drug in osteoporosis: from bench to marketing

W.H. Dere

12h00 - 12h10 Closing remarks S.E. Papapoulos

Thursday February 4, 2010

Programme valid as of October 20, 2009. IOF reserves the right to modify the programme, unilaterally and without notice.

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February 2-4, 2010Hôtel Lyon Métropole • Lyon, France

Training Course Registration FormEarly-bird registration deadline December 18, 2009 Registration deadline January 15, 2010Space is limited to 250 participants • Reserve your place now

Registrations will only be accepted with the return of full contact details of the delegate and registration payment. Please visit http://www.iofbonehealth.org/ltc2010 for online registration or for the editable PDF which can be e-mailed to IOF Nyon at [email protected] or faxed to +41 22 994 0101.

CME ACCREDITATIONThe International Osteoporosis Foundation is accredited by the European Accreditation Council for Con-tinuing Medical Education (EACCME) to provide the following CME activity for medical specialists. The EACCME is an institution of the European Union of Medical Specialists (UEMS), www.uems.net.

The 19th IOF Advanced Training Course on Osteoporosis is designated for a maximum of (or ‘for up to’) 15 hours of European external CME credits. Each medical specialist should claim only those hours of credit that he/she actually spent in the educational activity.

EACCME credits are recognized by the American Medical Association towards the Physician’s Recogni-tion Award (PRA). To convert EACCME credit to AMA PRA category 1 credit, contact the AMA.

Title Prof Dr Mr Mrs Ms Sex Male Female Nationality

First Name Family Name

Organization

Business Address

City State/Province Postal Code

Country Telephone Fax

E-mail

YOUR PROFILEPlease check the appropriate boxes below to indicate your profile

clinician scientistdoctor in general hospital or affiliate doctor in private practice or private hospitaldoctor or professor in university trainee or fellowindustry other

TRAINING COURSE REGISTRATION FEES

Until Dec 18, 2009 From Dec 19, 2009 to Jan 15, 2010

Sponsored* delegate E 985 E 1080

Non-sponsoredº delegate E 690 E 755

* Sponsored delegate any attendee whose registration, hotel and travel is underwritten or reimbursed by Industryº Non-sponsored delegate any attendee whose registration, hotel and/or travel is not underwritten or reimbursed by Industry

Registration fees do not include lunches and coffee breaks. This will be charged by the hotel or included in the accommodation package.

continued on next page ¦

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PAYMENT DETAILS TO AMIANDO AG, ON BEHALF OF IOFPayment(s)shouldbemadeinEuros(€).WeareunabletoacceptpersonalchequesandEurocheques.Pleaseindicatebelowwhichmethodofpaymentyouareusing.

Creditcard (statement will indicate Amiando AG)

AmericanExpress Visa MasterCard

Card# Expirydate KPN*

Cardholder’sname Signature

*Thecreditcardverificationnumber(KPN)isknownasCVV(CardVerificationValue)byVisaInternationalandasCVC(CardVerificationCode)byEurocard/MastercardandVisaCards.Thesenumberscanbefoundeitheronthereversesideofthecreditcardoronthefrontofthecardinthemiddleoftheright-handside.

Bank transfer (must include all bank charges)

Account holder Amiando AG • Tumbliengerstr. 23, DE-80 337 Munich, GermanyOn behalf of International Osteoporosis Foundation • 9 rue Juste-Olivier, CH-1260 Nyon, SwitzerlandBank Dresner Bank AG Paris • 5 boulevard de la Madeleine, FR-75 001 Paris, FranceBank code 11263 Account # 2003144 00EUAgency (guichet) 00001 Key (Clé RIB) 89SWIFT/BIC DRESFRPXXXX IBAN FR47 1126 3000 0120 0314 400 EU89

• pre-registration number and invoice will be sent to your e-mail address within 5 working days of reception by fax or email of editable PDF

• please mention your first and family name, IOF TC Lyon 2010 and invoice n° on the bank transfer

AIRPORT BUS TRANSFERDoyouwishtoreserveaseatonthecomplimentaryshuttlebustoLyonSt.Exupéryairportat12:30onThursday,February4,2010attheendofthecourse?

Yes No

VISA ATTESTATION REQUESTVisaAttestationwillonlybesentonrequesttofullypaidandregisteredparticipants.Tocheckwhetheryouneedavisa,pleasevisitwww.diplomatie.gouv.fr

PleasecheckthisboxifyourequireaVisaAttestationLetter

CANCELLATION AND NAME CHANGE POLICIES•ForcancellationsreceivedinwritingbyJanuary15,2010thecourseregistrationfeewillberefundedwithadeduction

of20%fromthisamountforadministrativecharges.•ThecourseregistrationfeewillnotberefundedforcancellationsreceivedafterJanuary16,2010.•Anadministrativefeeof60€willbechargedforanamechangeafterDecember19,2009.

GENERAL TERMS AND CONDITIONSThiscoursewillbelimitedto250participants.Applicationswillbeacceptedona‘first-paid,first-served’basis.Youwillreceiveacceptanceandconfirmationbye-mail.

IntheeventualitythattheIOFAdvancedTrainingCourseonOsteoporosiscannotbeheldorwillhavetobechangedduetoeventsbeyondthecontroloftheIOF(forcemajeureincluding,withoutlimitation,naturaldisasters,actsofGod,war,terrorismoranyactsoromissionsofthirdparties)orduetoeventswhicharenotattributabletowrongfulintentorgrossnegligenceoftheIOF,theIOFcannotbeheldliablebyparticipantsforanydamagesorcostsorlossincurred,suchastransportationcosts,hoteloraccommodationcosts,financialloss,etc.

Underthesecircumstances,theIOFreservestherighttoeitherholdtheentireregistrationfeeandtouseitforafutureIOFEvent,ortoreimbursetheregistrationfeeafterthedeductionofthecostsalreadyincurredfortheorganisationoftheIOFTrainingCourseandwhichcouldnotberecoveredfromthirdparties.

TheIOFreservestherighttomodifytheprogramme,unilaterallyandwithoutnotice.

TheIOFisnotresponsibleforanybodilyormaterialdamagesustainedbyparticipantsduringtheIOFAdvancedTrainingCourseonOsteoporosis,whichisnotdirectlythefaultoftheIOF.Eachparticipantisresponsibleforhisorherowninsuranceforsuchevents.

AnylitigationstemmingfromtheabovecontractwillbetriedinNyon,SwitzerlandwheretheSwisslawisexclusivelyapplicable.

IacceptthetermsandconditionsoftheIOFAdvancedTrainingCourseonOsteoporosisandherebyauthoriseIOFviaAmiandoAGtoreceivemyTrainingCourseregistrationpaymenttotheIOFbankaccount,ortodebitmycreditcardaccountforthetotalamountdue.IalsoconsenttoIOFdebitingorcreditingmycreditcardaccountwiththeamountofanysubsequentchange(s)totheitemsbooked.

Signature Date


M M Y Y

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Accommodation and Course MealsThe International Osteoporosis Foundation (IOF) has reserved a number of rooms at the Hôtel Lyon Métropole (4*), where the Advanced Training Course is held, and at the secondary downtown Boscolo Hôtel (4*). Please note that room charges are not included in the Advanced Training Course registration fee.

The hotel package includes either two or three nights between February 1-4, 2010 and covers accommodation, breakfast, and for registered participants, coffee breaks and lunches during the Training Course. The city tax of € 1.65 per person, per night is in addition. Pre-Stay (prior to Feb 1) and Post-Stay (from Feb 4) are possible upon request and availability at below quoted rates on a bed and breakfast basis (B&B) only. Rates are shown for standard rooms. Rates for other types of rooms (superior, deluxe, junior suites, etc.) are available upon request.

For your convenience, hotel requests can be made through IOF at the same time as the Advanced Training Course registration. The IOF cannot guarantee the rate nor the availability of the hotel rooms for participants registering after December 18, 2009 and assignment to either Métropole or Boscolo Hotels will be made on a ‘first-come, first-served’ basis.

Due to enhanced online security measures, the IOF cannot capture electronically credit card payment information to be submitted to a third party (Hôtel Métropole as a coordinating hotel).

Participants who do not need accommodation must still pay an amount of € 138 to cover lunches and coffee breaks.

No accommodation required • E 138 for conference lunches and coffee breaks will be charged by the Hôtel Lyon Métropole

MEALSDo you require a vegetarian meal at lunch?

Yes No

Other special diet/allergy

ACCOMMODATIONI am requesting, based on a ‘first-come, first-served’ basis

Hôtel Lyon Métropole (course venue) Boscolo Hôtel (downtown)85, quai Joseph Gillet 11, rue GroléeFR-69 004 Lyon, France FR-69 002 Lyon, FranceT + 33 4 72 10 44 44 T +33 4 72 40 45 45www.lyonmetropole.com www.boscolohotels.com

A complimentary shuttle bus will be available between the secondary downtown Hôtel Boscolo and the Hôtel Lyon Métropole.

Arrival date Departure date Number of nights

Twin room (2 beds) request King size bed request

If double/twin use, sharing with

First Name Family Name

Non-smoking request

tick appropriate option

2 nights Package

(including room, breakfast, conference package & Vat)

3 nights Package

(including room, breakfast, conference package & Vat)

B&B Pre-stay (Prior to FeB 1)B&B Post-stay (From FeB 4)(including bed, breakfast & Vat)

single occupancy E 584 E 764 E 180 per night for night(s)

double/twin occupancy* E 614 E 809 E 195 per night for night(s)Excluding € 1.65 city tax per night, per person • Inclusive of French VAT (19.6% in 2009) • All rates are quoted in Euros (€)

* Double/twin occupancy rate is meant for an accompanying person not participating to the Training Course

Hotel parking (at cost)

D D M M Y Y D D M M Y Y


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PAYMENT DETAILS TO HOTELPayment(s)shouldbemadeinEuros(€)andmadeouttotheHôtelLyonMétropole(coordinatoroftheaccommoda-tion).ThehotelsareunabletoacceptpersonalchequesandEurocheques.Pleaseindicatebelowwhichmethodofpaymentyouareusing,ifdifferentfromcourseregistration.

Creditcard AmericanExpress Visa MasterCard

Card# Expirydate KPN*

Cardholder’sname Signature

Bank transfer (must include all bank charges)

ACCOMMODATION TEMPORARY CONFIRMATION

Once the IOF has transferred your request, the Hôtel Lyon Métropole (coordinating hotel) will contact you within 5 business days with a temporary accommodation confirmation (against availability) that will be validated once you have submitted proof of financial guarantee directly to the hotel as:

▪ either a credit card number guarantee faxed or e-mailed back to the Hôtel Lyon Métropole (coordinating hotel); or

▪ a proof that a bank transfer has been requested with your bank and has been forwarded directly to the Hôtel Lyon Métropole (coordinating hotel).

Your temporary accommodation confirmation will be held for a maximum of 10 working days. The Coordinating Hotel reserves the right to cancel the pre-reservation, in case the payment by bank transfer for the hotel deposit is not received in their account within the given 10 working days or a credit card number as a payment guarantee has not been submitted within that same time period.The IOF will only act as a customer service intermediary between the hotels and the participants. The IOF will not bear any liability, nor financial responsibility towards the hotels, nor the participants. The IOF will not directly debit any deposit or penalty payments from your credit card for your hotel booking.

HOTEL CANCELLATION POLICY• ForcancellationsreceivedbyJanuary15,2010thehotelfeewillberefundedwithadeductionof20%.• ForcancellationsreceivedfromJanuary16,2010,thefullamountwillnotberefunded.

IacceptthetermsandconditionsoftheHotelandherebyauthorisethepre-selectedhoteltoreceivemyaccom-modationpaymenttotheHotelbankaccount,ortodebitmycreditcardaccountforthetotalamountdue.IalsoconsenttotheHoteldebitingorcreditingmycreditcardaccountwiththeamountofanysubsequentchange(s)totheitemsbooked.

FirstName FamilyName

Signature Date

For quicker service and up to date information, please register online at http://www.iofbonehealth.org/ltc2010

M M Y Y

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About IOFThe International Osteoporosis Foundation (IOF) is a non-governmental umbrella organization dedicated to the worldwide fight against osteoporosis, the disease known as “the silent epi-demic”. IOF’s members – committees of scientific researchers, patient, medical and research societies and industry representatives from around the world – share a common vision of a world without osteoporotic fractures. Launched in 1998 with the merger of the European Foundation for Osteoporosis (EFFO, founded in 1987) and the International Federation of Societies on Skel-etal Diseases, IOF now represents 193 societies in 92 locations.

IOF Mission and GoalsMission

▪ increase awareness and understanding of osteoporosis▪ support national osteoporosis societies in order to maximize their effectiveness▪ motivate people to take action to prevent, diagnose and treat osteoporosis

Goals▪ nurture and enlarge the IOF network of member societies worldwide▪ promote medical innovation and improved care▪ expand IOF partnerships with organizations working on similar or complementary issues and projects

▪ lobby for policy change in all countries so that diagnosis and treatment of osteoporosis be-comes routine

IOF EventsIOF looks forward to welcoming you to upcoming events:

▪ IOF WCO-ECCEO10 in Florence, Italy from May 5-8, 2010▪ ECCEO11-IOF WCO in Valencia, Spain from March 23-26, 2011▪ IOF Osteoporosis Diagnosis Courses with densitometry certification – held at various times and locations throughout the world

Visit the IOF website www.iofbonehealth.org to find out more about these and other events

Osteoporosisis a serious, disabling disease which affects millions of people around the world. With the number of sufferers expected to increase, osteoporosis poses a significant challenge to all health care professionals. The International Osteoporosis Foundation promotes research and trains medical professionals so that they are better equipped to handle this growing ‘epidemic’.

The IOF Advanced Training Course on Osteoporosisis taught in English by an internationally renowned faculty, providing a concise and practical overview of the latest knowledge on the physiology, epidemiology, diagnosis and management of osteoporosis. This course, held annually in Lyon since 1991, trains up to 250 international participants.

CME AccreditationThe International Osteoporosis Foundation is accredited by the European Accreditation Council for Continuing Medical Education (EACCME) to provide the following CME activity for medical specialists. The EACCME is an institution of the European Union of Medical Specialists (UEMS), www.uems.net.

The 19th IOF Advanced Training Course on Osteoporosis is designated for a maximum of (or ‘for up to’) 15 hours of European external CME credits. Each medical specialist should claim only those hours of credit that he/she actually spent in the educational activity.

EACCME credits are recognized by the American Medical Association towards the Physician’s Recognition Award (PRA). To convert EACCME credit to AMA PRA category 1 credit, contact the AMA.

The venueis centrally located in Lyon, one of France’s largest and most interesting cities. It is in Lyon and only in Lyon that:

▪ you can walk through 2000 years of history, stroll through the different neighbourhoods chosen by UNESCO as a part of World Heritage, and see everything from Roman architecture to today’s boldest creations;

▪ the museums cover very different specialities: silk, cinematography, fine arts, the French resistance, and sometimes surprising themes;

▪ you can succumb to the charm of a calm evening, by dining on a boat cruising gently on the Rhone and the Saone down to their confluence;

▪ you can taste cuisine from the world over, from the traditional Lyon “bouchons” to the most original “brasseries”, or savour the gourmet delights of Lyon’s multi-starred restaurants.

Quote from the Lyon Tourist Office www.lyon-france.com

International Osteoporosis Foundation9 rue Juste-Olivier • CH-1260 Nyon • SwitzerlandT. +41 22 994 01 00 • F. +41 22 994 01 [email protected] • www.iofbonehealth.org

Design and layout Gilberto Domingues Lontro IOFPhotos Tristan Deschamps Lyon Tourism Office

©2009 International Osteoporosis Foundation Printed on 100% recycled paper, with vegetable inks 09

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